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Medical Hypotheses

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1. Editorial Board

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1. Editorial Board

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1. Editorial Board

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1. Editorial Board

Tác giả

1. Editorial Board

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1. Editorial Board

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1. Editorial Board

Tác giả

2. Selective targeting of signet ring cell adenocarcinomas

Tác giả

Abdullah Olgun.

2. A new understanding of the principles in the management of complex anal fistula

Tác giả

Pankaj Garg.

2. Mental retardation in Down syndrome: Two ways to treat

Tác giả

Pierre P. Kamoun.

2. IL-1 blockers together with colchicine may be administered as first line therapy in familial Mediterranean fever with amyloidosis

Tác giả

Mehmet Engin Tezcan.

2. Publisher's Note

Tác giả

2. The Beehive Theory: Role of microorganisms in late sequelae of traumatic brain injury and chronic traumatic encephalopathy

Tác giả

Leslie C. Norins.

2. Medical hypothesis: Neurodegenerative diseases arise from oxidative damage to electron tunneling proteins in mitochondria

Tác giả

James P. Bennett.

2. Male PCOS equivalent and nutritional restriction: Are we stepping forward?

Tác giả

Federica Di Guardo, Maria Cecilia Cerana, Gisella D'urso, Fortunato Genovese, Marco Palumbo.

2. Hypothesis of the optimal therapeutic effect of transcranial direct current stimulation (tDCS) for psychiatric disorders: Integration of positive cognitive tasks during the neuroplastic process

Tác giả

Shih-Hsien Lin, Yen Kuang Yang.

2. Does the measurement of the difference of resistive indexes in spleen and kidney might be used for characterization of intrarenal tardus parvus phenomenon in chronic kidney disease?

Tác giả

Nordeval Cavalcante Araújo.

2. Expanding the spectrum of causative mutations of Marfan syndrome: Is there a role for the elastin gene?

Tác giả

Nicola Marziliano.

2. Network cultivation, diurnal cortisol and biological ageing: The rejuvenation hypothesis

Tác giả

Julian C.L. Lai, Daryl Y.H. Lee.

3. Adjunctive bradyzoite-directed therapy for reducing complications of congenital toxoplasmosis

Tác giả

Samuel D. Chorlton.

3. Will the long-term use of atropine eye drops in children increase the risk of dry eye?

Tác giả

Feng Zhao, Jing-xue Ma.

3. When an octopus has MS: Application of neurophysiology and immunology of octopuses for multiple sclerosis

Tác giả

Abdorreza Naser Moghadasi.

3. Alteration of scaffold: Possible role of MACF1 in Alzheimer’s disease pathogenesis

Tác giả

Xiaolong Wang, Yangyang Qi, Xin Zhou, Geyang Zhang, Caiyu Fu.

3. Is the endothelial cell responsible for the thrombus core and shell architecture?

Tác giả

Olufemi Emmanuel Kadri, Migle Surblyte, Vishnu Deep Chandran, Roman S. Voronov.

3. A hypothetic role of minocycline as a neuroprotective agent against methylphenidate-induced neuronal mitochondrial dysfunction and tau protein hyper-phosphorylation: Possible role of PI3/Akt/GSK3β signaling pathway

Tác giả

Pegah Salehi, Zhara Yaraei Shahmirzadi, Fatemeh Sadat Mirrezaei, Farima Shirvani Boushehri, Sepideh Safari.

3. Mucociliary transport as a link between chronic rhinosinusitis and trace element dysbalance

Tác giả

Svetlana I. Alekseenko, Anatoly V. Skalny, Olga P. Ajsuvakova, Margarita G. Skalnaya, Alexey A. Tinkov.

3. Are Clostridium difficile toxins nephrotoxic?

Tác giả

Nevio Cimolai.

3. Osteoporosis therapies might lead to intervertebral disc degeneration via affecting cartilage endplate

Tác giả

Zhen Sun, Zhuo-Jing Luo.

3. Myodesis or myoplasty in trans-femoral amputations. What is the best option? An explorative study

Tác giả

Jan H.B. Geertzen, Sanne M. van der Schans, Paul C. Jutte, Joep Kraeima, Rienk Dekker.

3. Aryl hydrocarbon receptor pathway participates in myocardial ischemia reperfusion injury by regulating mitochondrial apoptosis

Tác giả

Beibei Wang, Aijun Xu.

3. Differentiated thyroid cancer: Why does it affect predominantly women during the reproductive period and have higher incidence of mutual association with breast cancer?

Tác giả

Atsushi Kurata.

4. An ulcerated squamous cell carcinoma of the forehead in the artistic heritage of Lam qua

Tác giả

E. Porumb Andrese, C.F. Costea, A.I. Cucu, A. Perciaccante, M.D. Turliuc.

4. Shielding of non-target cells using RNA vectors conferring gene transfer resistance: A strategy to enhance targeting accuracy and reduce side-effects in therapeutic gene delivery

Tác giả

Oleg E. Tolmachov.

4. Serum nitric oxide levels correlate with quality of life questionnaires scores of hypothyroid females

Tác giả

Zoran M. Gluvic, Emina M. Sudar-Milovanovic, Vladimir S. Samardzic, Milan M. Obradovic, Esma R. Isenovic.

4. Sodium-glucose cotransporter 2 inhibition as a potential treatment for idiopathic oedema

Tác giả

Kirin Rambaran, Lexley Pinto Pereira, Surujpal Teelucksingh.

4. A new theory based on possible existence of timing control by intracellular photons in tonically active neurons

Tác giả

Hossein Mofidi, Yashar Sarbaz, Saeed Golmohammadi.

4. Was Blessed Jean Bassand affected by actinic keratoses?

Tác giả

R. Bianucci, N. Kluger, A. Perciaccante, O. Appenzeller, P. Charlier.

4. Removal of DNA adducts

Tác giả

B.K. Puri, C. Ijeh, J.A. Monro.

4. Gluteal muscle inhibition: Consequences of patellofemoral pain?

Tác giả

Neal R. Glaviano, David M. Bazett-Jones, Grant Norte.

4. Memory in the hippocampus

Tác giả

Bompei Yasui.

4. Frontal fibrosing alopecia: A new autoimmune entity?

Tác giả

Juan Esteban Garcia-Robledo, Cristian C. Aragón, Ivana Nieto-Aristizábal, Sara Vásquez, Gabriel J. Tobón.

4. Transient immunosuppression during short interruption of HAART: Another key to HIV cure in the “Berlin patient”?

Tác giả

Konstantin V. Suslov.

4. On infusion of high-dose ascorbate in treating cancer: Is it time for N-acetylcysteine pretreatment to enhance susceptibility and to lower side effects?

Tác giả

K. Valachová, I. Juránek, P. Rapta, I. Valent, L. Šoltés.

5. Cannabinoids Δ9-tetrahydrocannabinol and cannabidiol may be effective against methamphetamine induced mitochondrial dysfunction and inflammation by modulation of Toll-like type-4(Toll-like 4) receptors and NF-κB signaling

Tác giả

Fatemeh Majdi, Fereshteh Taheri, Pegah Salehi, Majid Motaghinejad, Sepideh Safari.

5. Sedative depth on neurological outcomes in a juvenile rat model of cardiopulmonary resuscitation

Tác giả

Jing Yuan, Meng-Chang Yang, Meng-Jun Wu, Yong-Sheng Gou.

5. Does a polarization state exist for mast cells in cancer?

Tác giả

Ivan Presta, Annalidia Donato, Paolo Zaffino, Maria Francesca Spadea, Giuseppe Donato.

5. A comprehensive model for the asthma paradox: Is asthma a protective or a risk factor for malignancy?

Tác giả

Soroush Seifirad.

5. The hypertension advantage and natural selection: Since type 2 diabetes associates with co-morbidities and premature death, why have the genetic variants remained in the human genome?

Tác giả

Matthew T. Lewis, Heidi L. Lujan, Robert W. Wiseman, Stephen E. DiCarlo.

5. Frontolimbic affective bias and false narratives from brain disease

Tác giả

Mario F. Mendez.

5. A deep learning-based decision support system for diagnosis of OSAS using PTT signals

Tác giả

Seda Arslan Tuncer, Beyza Akılotu, Suat Toraman.

5. A new proposal of utilizing intraoperative electron radiation therapy on the surface of liver to prevent postoperative liver metastasis of pancreatic cancer

Tác giả

Yiting Dong, Zikuan Song, Yuling Luo, Xuelei Ma.

5. Computer simulation of transfusion with different blood product ratios in modern massive transfusion protocols

Tác giả

Anthony M.-H. Ho, Adrienne K. Ho, Glenio B. Mizubuti.

5. Proposed dual antagonist approach for the prevention and treatment of urinary tract infections caused by uropathogenic Escherichia coli

Tác giả

Rosana Ribić, Tomislav Meštrović, Marijana Neuberg, Goran Kozina.

5. Adiponectin: A potential candidate for treating fibrosis in posterior segment of the eye

Tác giả

Karthikka Palanisamy, Rajiv Raman, Konerirajapuram Natarajan Sulochana, Subbulakshmi Chidambaram.

5. The importance of inhibition of a catabolic pathway of methotrexate metabolism in its efficacy for rheumatoid arthritis

Tác giả

Sarah L. Morgan, Joseph E. Baggott.

6. Quantum nature of consciousness – Double slit diffraction experiment in medicine

Tác giả

Andreja Vujanac, Ivan Srejovic, Vladimir Zivkovic, Nevena Jeremic, Vladimir Jakovljevic.

6. Nutraceutical targeting of TLR4 signaling has potential for prevention of cancer cachexia

Tác giả

Mark F. McCarty, Simon Iloki-Assanga, Lidianys Maria Lewis Lujany.

6. Post traumatic retinal injuries: Does the ocular protective reflex play a crucial role?

Tác giả

Amar Pujari, Rohan Chawla, Harathy Selvan, Ritika Mukhija, Atul Kumar.

6. A pyruvate dehydrogenase complex disorder hypothesis for bipolar disorder

Tác giả

Iain Campbell, Harry Campbell.

6. Detection of microaneurysms using ant colony algorithm in the early diagnosis of diabetic retinopathy

Tác giả

Turab SELÇUK, Ahmet ALKAN.

6. Otoconial loss or lack of otoconia – An overlooked or ignored diagnosis of balance deficits

Tác giả

S.C.A. Hegemann, C.J. Bockisch.

6. Possible participation of colloid antigen 2 and abhormone (IgG with hormone activity) for the etiology of Graves’ disease

Tác giả

Yukio Ochi.

6. Could ornithine supplementation be beneficial to prevent the formation of pro-atherogenic carbamylated low-density lipoprotein (c-LDL) particles?

Tác giả

Bahadir Simsek, Ufuk Çakatay.

6. A post-surgical adjunctive hypoxic therapy for myocardial infarction: Initiate endogenous cardiomyocyte proliferation in adults

Tác giả

Jing-Zhang Wang, Yu-Hua Zhang, Wen-Tao Du, Guang Liu, Xin-Hua Guo.

6. Crocin may be useful to prevent or treatment of alcohol induced neurodegeneration and neurobehavioral sequels via modulation of CREB/BDNF and Akt/GSK signaling pathway

Tác giả

Majid Motaghinejad, Sepideh Safari, Saba Feizipour, Samira Sadr.

6. Prisoner exposure to nature: Benefits for wellbeing and citizenship

Tác giả

John R. Reddon, Salvatore B. Durante.

6. Hypothesis related to the regulation of inducible nitric oxide synthase during carotid endarterectomy

Tác giả

M. Obradovic, N. Bogdanovic, J. Stanimirovic, D. Unic-Stojanovic, E.R. Isenovic.

7. Postmortem vs. neoplastic gene expression: Clues to cancer development and therapy

Tác giả

Michael Bordonaro.

7. Antihistamine agents and pitolisant might be useful for anorexia nervosa

Tác giả

Barbara Scolnick.

7. A potential role of toll-like receptors, IFN-γ and the phosphatidylinositol 3-kinase pathway in the pathogenesis of acquired mediastinal lymphatic malformation

Tác giả

Pradeep Goyal, Sonali Gupta, Priti Soin, Joseph Mattana.

7. Planarity of the spatial QRS loop of vectorcardiogram is a crucial diagnostic and prognostic parameter in acute myocardial infarction

Tác giả

Sayantani Choudhuri, Tania Ghosal, Damodar Prasad Goswami, Arnab Sengupta.

7. The gadolinium hypothesis for fibromyalgia and unexplained widespread chronic pain

Tác giả

Silvia Maria Lattanzio.

7. KAMST – Simple method for patients with migraine screening

Tác giả

Antanas Vaitkus, Raminta Macaitytė, Inga Kiudulaitė.

7. Improving autism perinatal risk factors: A systematic review

Tác giả

Jenna Cheng, Brenda Eskenazi, Felicia Widjaja, José F. Cordero, Robert L. Hendren.

7. The correlative hypotheses between Pitchfork and Kif3a in palate development

Tác giả

Shujin Li, Shan Jin, Chengri Jin.

7. Psychedelic medicine: The biology underlying the persisting psychedelic effects

Tác giả

K.P.C. Kuypers.

7. Depleted uranium induces human carcinogenesis involving the immune and chaperoning systems: Realities and working hypotheses

Tác giả

Francesco Cappello, Alberto J.L. Macario.

7. The reproductive life cycle of cancer: Hypotheses of cell of origin, TP53 drivers and stem cell conversions in the light of the atavistic cancer cell theory

Tác giả

Vladimir F. Niculescu.

7. A potential treatment of low intensity pulsed ultrasound on cavernous nerve injury for erectile dysfunction

Tác giả

Pai-Kai Chiang, Feng-Yi Yang.

8. A combined astrocyte – G-lymphatic model of epilepsy initiation, maintenance and termination

Tác giả

Avinoam Rabinovitch, Ira Aviramd, Yaacov Biton, Doron Braunstein.

8. Amphetamine exposure and dementia – A hypothesis of the long term sequelae of cognitive enhancers based on opponent process theory

Tác giả

Nian-Sheng Tzeng, Yia-Ping Liu.

8. Apnea events in neonatal age: A case report and literature review

Tác giả

Raffaele Falsaperla, Giovanna Vitaliti, Carla Cimino, Stefano Catanzaro, Giovanni Corsello.

8. Dissociative identity as a continuum from healthy mind to psychiatric disorders: Epistemological and neurophenomenological implications approached through hypnosis

Tác giả

Enrico Facco, Laura Mendozzi, Angelo Bona, Achille Motta, Susanna Lipari.

8. Role of leptin as a biomarker for early detection of renal cell carcinoma? No evidence from a systematic review and meta-analysis

Tác giả

Komathi Perumal, Weng Kit Huin, Ning Yi Yap, Teng Aik Ong, Retnagowri Rajandram.

8. Potential role of calcifying nanoparticles in the etiology of multiple sclerosis

Tác giả

Birsen Can Demirdöğen.

8. Emotion recognition through EEG phase space dynamics and Dempster-Shafer theory

Tác giả

Morteza Zangeneh Soroush, Keivan Maghooli, Seyed Kamaledin Setarehdan, Ali Motie Nasrabadi.

8. Skeletal muscle as a protagonist in the pregnancy metabolic syndrome

Tác giả

Raul Narvaez-Sanchez, Juan C. Calderón, Gloria Vega, Maria Camila Trillos, Sara Ospina.

8. Exaggerated arterial curves due to endovascular interventions: Novel concept that describes how curves in the arterial wall affect the formation of neointimal hyperplasia, and explains why the long-term results of endovascular interventions are inferior t

Tác giả

Amr Salem.

8. Is polycystic ovary syndrome a 20th Century phenomenon?

Tác giả

Raymond J. Rodgers, Larisa Suturina, Daria Lizneva, Michael J. Davies, Sarah A. Robertson.

8. Bioengineering application using co-cultured mesenchymal stem cells and preosteoclasts may effectively accelerate fracture healing

Tác giả

Weiduo Hou, Chenyi Ye, Weixu Li, Wei Zhang, Qiang Zheng.

8. Aerobic exercise promotes the expression of ERCC1 to prolong lifespan: A new possible mechanism

Tác giả

Naichun Ji, Wenpeng Zhao, Huiming Qian, Xinyu Yan, Kejing Lao.

9. Towards a new model of understanding – The triple network, psychopathology and the structure of the mind

Tác giả

Bindu Menon.

9. Fluid dynamics approach to airway obstruction

Tác giả

Norihiko Tsuboi, Shotaro Matsumoto, Nao Nishimura, Satoshi Nakagawa, Hisato Kobayashi.

9. Are caffeine’s performance-enhancing effects partially driven by its bitter taste?

Tác giả

Craig Pickering.

9. Is increased plasma TMAO a compensatory response to hydrostatic and osmotic stress in cardiovascular diseases?

Tác giả

M. Ufnal, A. Nowiński.

9. Central hypersensitivity – A model for persistent musculoskeletal pain in inflammatory bowel diseases

Tác giả

Carrie Falling, Simon Stebbings, G David Baxter, Ramakrishnan Mani.

9. Are the antidepressive effects of massage therapy mediated by restoration of impaired interoceptive functioning? A novel hypothetical mechanism

Tác giả

Michael Eggart, Silvia Queri, Bruno Müller-Oerlinghausen.

9. Sarcopenia as a potential cause of chronic hyponatremia in the elderly

Tác giả

Natalia Bertini, Chiara Nicoletti, Braian M. Beker, Carlos G. Musso.

9. A ‘pathogenic needle’ in a ‘commensal haystack’: Genetic virulence signatures of Corynebacterium glucuronolyticum that may drive its infectious propensity for the male urogenital system

Tác giả

Tomislav Meštrović, Jonas Wilson, Sunčanica Ljubin-Sternak, Mario Sviben, Goran Kozina.

9. Pathomechanism of optic nerve avulsion

Tác giả

Amar Pujari, Rohit Saxena, Swati Phuljhele, Karthika Bhaskaran, Pradeep Sharma.

9. Surfactant proteins: Role in lacrimal drainage disorders

Tác giả

Mohammad Javed Ali, Friedrich Paulsen.

9. A human mode of intestinal type gastric carcinoma

Tác giả

Shaoqing Lai.

9. Pleiotropic functions of plasmacytoid dendritic cells in the pathogenesis of the rheumatoid arthritis

Tác giả

Semyon V. Kupriyanov, Anton I. Sinitskii.

10. Relating the Diers formetric measurements with the subjective severity of acute and chronic low back pain

Tác giả

Inge Roman, Michiel Luyten, Hendrik Croonenborghs, Grégoire Lason, Frank Comhaire.

10. Have public hospitals outlived their usefulness? Is it possible to assess with health care parameters the impact of public hospitals on major American cities?

Tác giả

Wayne X. Shandera.

10. High lithium levels in tobacco may account for reduced incidences of both Parkinson’s disease and melanoma in smokers through enhanced β-catenin-mediated activity

Tác giả

Thomas Guttuso.

10. Motor repertoire and gray matter plasticity: Is there a link?

Tác giả

Alexandre Jehan Marcori, Victor Hugo Alves Okazaki.

10. A novel approach in the management of hyperhomocysteinemia

Tác giả

Shaiba Sana Qureshi, Jeetendra Kumar Gupta, Ahsas Goyal, Harlokesh Narayan Yadav.

10. The sequencing process generated by the cerebellum crucially contributes to social interactions

Tác giả

Frank Van Overwalle, Mario Manto, Maria Leggio, José María Delgado-García.

10. Structural valve deterioration does not alter tissue valves’ radiopaque landmarks: Implications for valve-in-valve therapy

Tác giả

Réda Belhaj Soulami, Miguel Castro, Pascal Haigron, Jean-Philippe Verhoye.

10. Anti-caries vaccine based on clinical cold-adapted influenza vaccine: A promising alternative for scientific and public-health protection against dental caries

Tác giả

Huixiao Yang, Zhonghai Yan, Zijian Zhang, Adilene Realivazquez, Yi Liu.

10. Mysterious effects of olfactory pathway lesions on intestinal immunodeficiency targeting Peyer’s patches: The first experimental study

Tác giả

Binali Firinci, Ozgur Caglar, Erdem Karadeniz, Ali Ahiskalioglu, Mehmet Dumlu Aydin.

10. Psychosis is an extension of mood swings from the perspective of neuronal plasticity impairments

Tác giả

T. Mizuno, H. Matsumoto, K. Mita, S. Kogauchi, N. Omata.

10. Hypothesis regarding the effects of gonadotropins on the level of free fatty acids and phospholipids in serum and follicular fluid during controlled ovarian stimulation

Tác giả

Milan D. Perovic, Emina M. Sudar-Milovanovic, Ema D. Simonovic, Ivana M. Resanovic, Esma R. Isenovic.

10. β-PVDF based electrospun nanofibers – A promising material for developing cardiac patches

Tác giả

Ratnakar Arumugam, Endu Sekhar Srinadhu, Balanehru Subramanian, Satyanarayana Nallani.

11. A 4-D approach for amelioration of periodontitis

Tác giả

Pooja Jain, M. Aamir Mirza, Zeenat Iqbal.

11. Airborne contamination and surgical site infection: Could a thirty-year-old idea help solve the problem?

Tác giả

Mikael Persson.

11. Fluid dynamics of thoracic cavity venous flow in multiple sclerosis

Tác giả

Trevor Tucker.

11. Molecular biology of autism’s etiology – An alternative mechanism

Tác giả

Gary Steinman, David Mankuta.

11. CD133 receptor mediated delivery of STAT3 inhibitor for simultaneous elimination of cancer cells and cancer stem cells in oral squamous cell carcinoma

Tác giả

Sai Harshini Pindiprolu, Sai Kiran S.S. Pindiprolu.

11. Photogrammetry as an alternative for acquiring digital dental models: A proof of concept

Tác giả

Vitor T. Stuani, Rafael Ferreira, Gustavo G.P. Manfredi, Matheus V. Cardoso, Adriana C.P. Sant'Ana.

11. The 22q11.2 deletion syndrome as a model for idiopathic scoliosis – A hypothesis

Tác giả

Jelle F. Homans, Steven de Reuver, Elemi J. Breetvelt, Jacob A.S. Vorstman, René M. Castelein.

11. A single preoperative pain neuroscience education: Is it an effective strategy for patients with carpal tunnel syndrome?

Tác giả

Rodrigo Núñez-Cortés, César Espinoza-Ordóñez, Paula Pino Pommer, Giselle Horment-Lara, Carlos Cruz-Montecinos.

11. Percolation theory for the recognition of patterns in topographic images of the cortical activity

Tác giả

Francisco Gerson A. de Meneses, Gildário Dias Lima, Monara Nunes, Victor Hugo Bastos, Silmar Teixeira.

11. Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5

Tác giả

B.K. Puri, M.C. Kingston, J.A. Monro.

11. A theory of general intelligence

Tác giả

Hin Wai Lui.

11. The Sudden Infant Death Syndrome mechanism of death may be a non-septic hyper-dynamic shock

Tác giả

Uri Gabbay, Doron Carmi, Einat Birk, David Dagan, Debora Kidron.

12. 3D-printed nerve conduit with vascular networks to promote peripheral nerve regeneration

Tác giả

Jie Tao, Yan He, Shuai Wang, Jian Mao.

12. Why intraperitoneal glucose sensing is sometimes surprisingly rapid and sometimes slow: A hypothesis

Tác giả

Marte Kierulf Åm, Anders Lyngvi Fougner, Reinold Ellingsen, Dag Roar Hjelme, Sverre Christian Christiansen.

12. Fluid dynamics of cerebrospinal venous flow in multiple sclerosis Trevor Tucker.

Tác giả

Trevor Tucker.

12. Could cyanogenic glycoside rich diet cause increased risk for carbamylation-induced protein damage in individuals with chronic inflammatory diseases?

Tác giả

Bahadir Simsek, Ufuk Çakatay.

12. Weight velocity equations with 14–448 days time separated weights should not be used for infants under 3 years of age

Tác giả

Martin J.C. van Gemert, Cornelis M.A. Bruijninckx, H.A. Martino Neumann, Pieter J.J. Sauer, Ton G. van Leeuwen.

12. Spontaneous coronary artery dissection and associated myocardial bridging: Current evidence from cohort study and case reports

Tác giả

Farbod Zahedi Tajrishi, Asrar Ahmad, Adeel Jamil, Sadaf Sharfaei, Gerald Chi.

12. Hypothetical role of gravity in Rapid Eye Movements during sleep

Tác giả

Alain A. Gonfalone.

12. An integrated model of acute exercise on memory function

Tác giả

Paul D. Loprinzi.

12. Could the high consumption of high glycaemic index carbohydrates and sugars, associated with the nutritional transition to the Western type of diet, be the common cause of the obesity epidemic and the worldwide increasing incidences of Type 1 and Type 2 d

Tác giả

Sture Sjöblad.

12. Cellular stress and AMPK links metformin and diverse compounds with accelerated emergence from anesthesia and potential recovery from disorders of consciousness

Tác giả

Jahahreeh Finley.

12. Subcortical visual pathway may be a new way for early diagnosis of glaucoma

Tác giả

Yi Sun, Wenbin Huang, Fei Li, Hao Li, Xiulan Zhang.

12. Reverse phenotype transfer via fecal microbial transplantation in inflammatory bowel disease

Tác giả

Robert Liptak, Barbora Gromova, Martin Maronek, Roman Gardlik.

13. Oxytocin is a principal hormone that exerts part of its effects by active fragments

Tác giả

Kerstin Uvnäs Moberg, Linda Handlin, Kathleen Kendall-Tackett, Maria Petersson.

13. Tubal muscles determine embryo implantation site; prognosis of ectopic pregnancy at chronic functional disorders

Tác giả

Galina A. Pavlova.

13. Possible role of rivoglitazone thiazolidine class of drug as dual-target therapeutic agent for bacterial infections: An in silico study

Tác giả

Yele, Niladri Saha, Afzal Azam Md.

13. The incidence of anxiety may not be correlated with severity of psoriasis: A prospective pilot study

Tác giả

Sebastian Yu, Hung-Pin Tu, Yu-Chi Huang, Cheng-Che E. Lan.

13. The use of Chinese finger trap as a metaphor: A way to promote adherence to medical treatment for chronically ill patients

Tác giả

Ozan Bahcivan.

13. RF9: May it be a new therapeutic option for hypogonadotropic hypogonadism?

Tác giả

Zafer Sahin, Haluk Kelestimur.

13. Can an amino acid-based oral rehydration solution be effective in managing immune therapy-induced diarrhea?

Tác giả

J.D. Hendrie, A. Chauhan, N.R. Nelson, L.B. Anthony.

13. Natural fiber reinforced biodegradable staples: Novel approach for efficient wound closure

Tác giả

P.C. Lalhmangaihzuali, B. Divya Latha, Namdev More, Mounika Choppadandi, Govinda Kapusetti.

13. Is muscle growth a mechanism for increasing strength?

Tác giả

Jeremy P. Loenneke, Scott J. Dankel, Zachary W. Bell, Samuel L. Buckner, Takashi Abe.

13. Cannabis use during pregnancy: Are we at the verge of defining a “fetal cannabis spectrum disorder”?

Tác giả

S. Schreiber, C.G. Pick.

13. Does aerobic exercise induced-analgesia occur through hormone and inflammatory cytokine-mediated mechanisms in primary dysmenorrhea?

Tác giả

Priya Kannan, Kwok-Kuen Cheung, Benson Wui-Man Lau.

13. IGF – Autism prevention/amelioration

Tác giả

Gary Steinman.

14. Baseline of upper teeth: (a) Control organ for spatial navigation? (b) Weak point for misaligned posture and pain?

Tác giả

Anne Kapp, Marianne Paethke, Manfred Baqué, Ruth Nebel.

14. Can curcumin along with chemotherapeutic drug and lipid provide an effective treatment of metastatic colon cancer and alter multidrug resistance?

Tác giả

Chenmala Karthika, Raman Sureshkumar.

14. Eye movement desensitization and reprocessing for post-traumatic stress disorder from the perspective of three-dimensional model of the experiential selfhood

Tác giả

Andrew A. Fingelkurts, Alexander A. Fingelkurts.

14. Lysyl oxidase in oral cancer: Friend or foe?

Tác giả

Gargi S. Sarode, Sachin C. Sarode, Amol R. Gadbail, Shailesh Gondivkar, Shankargouda Patil.

14. Hypoxia inducible factors as mediators of reactive oxygen/nitrogen species homeostasis in physiological normoxia

Tác giả

Jeffrey A. Stuart, Odosa Aibueku, Olivia Bagshaw, Fereshteh Moradi.

14. Fluorine may intensify the mechanisms of polycystic ovary syndrome (PCOS) development via increased insulin resistance and disturbed thyroid-stimulating hormone (TSH) synthesis even at reference levels

Tác giả

Małgorzata Szczuko, Joanna Splinter, Marta Zapałowska-Chwyć, Maciej Ziętek, Dominika Maciejewska.

14. Chaos, mitochondria and type 2 diabetes; does type 2 diabetes arise from a metabolic dysrhythmia?

Tác giả

Richard Baskerville.

14. The olfactory bulb: A link between environmental agents and narcolepsy Isamu Mori.

Tác giả

Isamu Mori.

14. The physical nature of subjective experience and its interaction with the brain

Tác giả

Fredric Schiffer.

14. Field dynamics in atrioventricular activation. Clinical evidence of a specific field-to-protein interaction

Tác giả

Manel Ballester-Rodés, Francesc Carreras-Costa, Teresa Versyp-Ducaju, Montserrat Ballester-Rodés, Davendra Mehta.

14. Density difference between perilymph and endolymph: A new hypothesis for light cupula phenomenon

Tác giả

Chang-Hee Kim, Ngoc Chien Pham.

14. Nodular rheumatoid arthritis (RA): A distinct disease subtype, initiated by cadmium inhalation inducing pulmonary nodule formation and subsequent RA–associated autoantibody generation

Tác giả

D. Murphy, E. Sinha–Royle, K. Bellis, C. Harrington, D. Hutchinson.

15. Collapsibility of the internal jugular veins in the lateral decubitus body position: A potential protective role of the cerebral venous outflow against neurodegeneration

Tác giả

M. Simka, J. Czaja, D. Kowalczyk.

15. Hypothesis: Mechanism of irritable bowel syndrome in inflammatory bowel disease

Tác giả

Yoshiharu Uno.

15. The olfactory bulb: A link between environmental agents and narcolepsy, from the standpoint of autoimmune etiology

Tác giả

Isamu Mori.

15. Dental occlusion as one cause of tinnitus

Tác giả

Jose Luiz Villaça Avoglio.

15. No common denominator: Plant-based diets and treatment-induced neuropathy of diabetes

Tác giả

Maximilian Andreas Storz.

15. A new approach for digestive disease diagnosis: Dynamics of gastrointestinal electrical activity

Tác giả

Roham Mazloom.

15. Are rises in Electro-Magnetic Field in the human environment, interacting with multiple environmental pollutions, the tipping point for increases in neurological deaths in the Western World?

Tác giả

Colin Pritchard, Anne Silk, Lars Hansen.

15. The psycho-periodic cube

Tác giả

Mehmet Emin Ceylan, Alper Evrensel, Aslıhan Dönmez, Barış Önen Ünsalver, Ahmet Mete Çom.

15. Seeing the wood for the trees: A new way to view the human intestinal microbiome and its connection with non-communicable disease

Tác giả

Sohan Jheeta, David Smith.

15. Laparoscopic promontofixation: Where to stop the anterior dissection?

Tác giả

Nassir Habib, Gabriele Centini, Anne-Cecile Pizzoferrato, Charles Bui, Georges Bader.

15. Cancer related fatigue and cancer cachexia are the consequence of endocrine failure caused by persistent stress

Tác giả

Shaoqing Lai.

15. Rheumatoid arthritis revisited

Tác giả

Mika Yrjö Suominen.

16. Predicted economic damage from a quick, simple Alzheimer's disease cure

Tác giả

Leslie C. Norins.

16. Efficacy of low molecular weight heparin in spinal trauma patients after part concentrated screw surgery and its influence on blood parameters and the incidence of deep venous thrombosis

Tác giả

W. Shiqing, M. Shengzhong, Z. Cheng, C. Guangqing, G. Chunzheng.

16. Immunization against environmental chemical carcinogens: Pro and contra

Tác giả

Andrew N. Glushkov, Elena G. Polenok, Stella A. Mun, Lyudmila A. Gordeeva.

16. Broadening the horizon: Integrative pharmacophore-based and cheminformatics screening of novel chemical modulators of mitochondria ATP synthase towards interventive Alzheimer’s disease therapy

Tác giả

Iwuchukwu A. Emmanuel, Fisayo Olotu, Clement Agoni, Mahmoud E.S. Soliman.

16. What is the optimal femur length in a trans-femoral amputation? A mixed method study: Scoping review, expert opinions and biomechanical analysis

Tác giả

Jan H.B. Geertzen, Marloes C. de Beus, Paul C. Jutte, Egbert Otten, Rienk Dekker.

16. Vitiligo and Hashimoto’s thyroiditis: Autoimmune diseases linked by clinical presentation, biochemical commonality, and autoimmune/oxidative stress-mediated toxicity pathogenesis

Tác giả

Dongmei Li, Guanzhao Liang, Richard Calderone, Joseph A. Bellanti.

16. Beneficial effect of sugar-sweetened beverages on the risk of urinary tract infections

Tác giả

Jozef Čonka, Veronika Melišková, Roman Gardlík, Július Hodosy, Ľubomíra Tóthová.

16. Possible role of Thiazolidinedione in the management of Type-II Endometrial Cancer

Tác giả

Kusuma Kumari Garikapati, V.V.V. Ravi Kiran Ammu, Praveen T. Krishnamurthy, Pavan Kumar Chintamaneni, Sai kiran S.S. Pindiprolu.

16. Hypothesis: Can drug-loaded platelets be used as delivery vehicles for blood-brain barrier penetration?

Tác giả

S.M. Kola, P. Kumar, Y.E. Choonara, L.C. du Toit, V. Pillay.

16. Pathomechanism of traumatic indirect choroidal rupture

Tác giả

Amar Pujari, Rohan Chawla, Divya Agarwal, Meghal Gagrani, Atul Kumar.

16. Is the “lactormone” a key-factor for exercise-related neuroplasticity? A hypothesis based on an alternative lactate neurobiological pathway

Tác giả

Renato Sobral-Monteiro-Junior, Pauline Maillot, Valeska Gatica-Rojas, Waldney Roberto M. Ávila, Andréa Camaz Deslandes.

16. Intrathecal cerebrospinal fluid infusion as a potential therapeutic strategy for Alzheimer’s disease

Tác giả

Peter Wostyn, Debby Van Dam, Peter Paul De Deyn.

17. Correction of rotational deformity and restoration of thoracic kyphosis are inversely related in posterior surgery for adolescent idiopathic scoliosis

Tác giả

E. Acaroglu, M. Doany, E. Cetin, R. Castelein.

17. Does high-dose gestational folic acid increase the risk for autism? The birth order hypothesis

Tác giả

Gideon Koren, Sarah Sharman Moser.

17. Peptidase neurolysin is an endogenous cerebroprotective mechanism in acute neurodegenerative disorders

Tác giả

Vardan T. Karamyan.

17. Suggested pathology of systemic exertion intolerance disease: Impairment of the E3 subunit or crossover of swinging arms of the E2 subunit of the pyruvate dehydrogenase complex decreases regeneration of cofactor dihydrolipoic acid of the E2 subunit

Tác giả

Victoria J. Berdikova Bohne, Øyvind Bohne.

17. Ivabradine modulates the autonomic nervous system by affecting the “little brain” of the heart: A hypothesis

Tác giả

Tomas Baka, Fedor Simko.

17. Beta-blockers in non-surgical patients with type A aortic dissection

Tác giả

Shay Brikman, Guy Dori.

17. A great legal scholar of the 18th century with liver cirrhosis and septicemia

Tác giả

R. Bianucci, L. Abenavoli, P. Charlier, D. Lippi, A. Perciaccante.

17. It is time to investigate integrative approaches to enhance treatment outcomes for depression?

Tác giả

Adrian L. Lopresti.

17. Low-intensity current (LIC) stimulation of subcutaneous adipose derived stem cells (ADSCs) – A missing link in the course of LIC based wound healing

Tác giả

Ravindra V. Badhe, Sonali S. Nipate.

17. RISUG® based improved intrauterine contraceptive device (IIUCD) could impart protective effects against development of endometrial cancer

Tác giả

Bhuvaneshwaran Subramanian, Tarun Agarwal, Piyali Basak, Tapas Kumar Maiti, Sujoy K. Guha.

17. Is vitamin D deficiency behind the scenes for high incidence of Giant cell tumor amongst the Indian population? Unraveling the vitamin D – RANKL association

Tác giả

Manit K. Gundavda, Manish G. Agarwal, Rajeev Reddy, Yash Wagh, Vinayak Ghanate.

17. Role of sleep deprivation in the causation of postpartum obsessive-compulsive disorder

Tác giả

Verinder Sharma.

18. Hypothermia-rewarming: A Double-edged sword?

Tác giả

Yi Hou, Yuanyuan Qiao, Ming Xiong, Dajin Zhang, Chenghe Shi.

18. Would acetazolamide inhibit progression of atheromatous vascular calcification?

Tác giả

Malcolm Cochran.

18. Is ulcerative colitis a disease of a dysfunctional microbiota?

Tác giả

Gilles R.G. Monif.

18. The iso-osmo-resistivity theory of digestion

Tác giả

John Andrew Sutton.

18. The biomechanical function of the foot pump in venous return from the lower extremity during the human gait cycle: An expansion of the gait model of the foot pump

Tác giả

Andy Horwood.

18. Recent trend of increasing myopia can be traced to infancy

Tác giả

Koji Matsuda, Keunsik Park.

18. “3M”: Migraine, Microbiota and Melatonin

Tác giả

N. Boutrid, H. Rahmoune.

18. Developmental social vulnerability as the intrinsic origin of psychopathology: A paradigm shift from disease entities to psychiatric derivatives within human diversity

Tác giả

Hirofumi Morioka, Shinji Ijichi, Naomi Ijichi, Yukina Ijichi, Bryan H. King.

18. The consumption of snacks and soft drinks between meals may contribute to the development and to persistence of gastro-esophageal reflux disease

Tác giả

E. Fiorentino.

18. Impact of parenting on the development of chronic diseases in adulthood

Tác giả

Lisa B.E. Shields, Kenneth C. Wilson, Steven T. Hester, Joshua T. Honaker.

18. The importance of ergothioneine synthesis in ancient time by organisms living in oxygen free atmosphere

Tác giả

Katarína Valachová, Mojmír Mach, Michal Dubovický, Ladislav Šoltés.

18. Deciphering the metabolic secret of longevity through the analysis of metabolic response to stress on long-lived species

Tác giả

Philippe de Medina.

19. Hyper-serotonergic state determines onset and progression of idiopathic Parkinson’s disease

Tác giả

Eliseu da Cruz Moreira-Junior.

19. Quantification of randomness (Entropy) as a clinical tool to assess the severity of skin disease

Tác giả

Alina Breslavets, Maksym Breslavets, Neil H. Shear.

19. The possible synergistic action of sex hormones and glucagon-like peptide-1 (GLP-1) agonists on body mass decline in patients with type 2 diabetes mellitus

Tác giả

T. Režić, K. Blaslov, I. Kruljac, D. Rahelić, I.P. Renar.

19. A potential factor in the pathophysiology of lateral epicondylitis: The long sarcomere length of the extensor carpi radialis brevis muscle and implications for physiotherapy

Tác giả

Zilan Bazancir, Tüzün Fırat.

19. ‘The hunger trap hypothesis’: New horizons in understanding the control of food intake

Tác giả

Nazli Aytekin, Banu Godfri, Adam Cunliffe.

19. New idea for hair transplantation to preserve more donor hair follicles

Tác giả

Hsi-An Chen, Jiun-Yit Pan, Chi-Hsiang Chiang, An-Hua Jhang, Wen-Tsao Ho.

19. Is infrared thermography (IRT) a possible tool for the evaluation and follow up of Emery-Dreifuss muscular dystrophy? A preliminary study

Tác giả

A. Cabizosu, N. Carboni, A. Figus, J.M. Vegara-Meseguer, A. Martinez-Almagro Andreo.

19. A hypothesis on paradoxical privileged portal vein metastasis of hepatocellular carcinoma. Can organ evolution shed light on patterns of human pathology, and vice versa?

Tác giả

Vladimir M. Subbotin.

19. Long term drug related remission may encourage drug withdrawal in patients with rheumatoid arthritis

Tác giả

Mehmet Engin Tezcan.

19. A minimally invasive robotic surgery approach to perform totally endoscopic coronary artery bypass on beating hearts

Tác giả

Alireza Alamdar, Shahrzad Hanife, Farzam Farahmand, Saeed Behzadipour, Alireza Mirbagheri.

19. EEG coherence as a diagnostic tool to measure the initial stages of Parkinson Disease

Tác giả

Mariana Gongora, Bruna Velasques, Mauricio Cagy, Silmar Teixeira, Pedro Ribeiro.

19. Activation of the intracellular temperature and ROS sensor membrane protein STIM1 as a mechanism underpinning biological effects of low-level low frequency magnetic fields

Tác giả

Myrtill Simkó, Mats-Olof Mattsson.

20. Medical knowledge integration and “systems medicine”: Needs, ambitions, limitations and options

Tác giả

Felix Tretter, Henriette Löffler-Stastka.

20. Speech-ABR in contralateral noise: A potential tool to evaluate rostral part of the auditory efferent system

Tác giả

Yones Lotfi, Abdollah Moossavi, Mohanna Javanbakht, Soghrat Faghih Zadeh.

20. Clinical and diagnostic features of patients with familial multiple sclerosis

Tác giả

Denas Andrijauskis, Renata Balnyte, Ieva Keturkaite, Antanas Vaitkus.

20. In silico rational design of a novel tetra-epitope tetanus vaccine with complete population coverage using developed immunoinformatics and surface epitope mapping approaches

Tác giả

Samira Bazmara, Mahsa Shadmani, Atefeh Ghasemnejad, Hossein Aghazadeh, Kamran Pooshang Bagheri.

20. Vitamin D supplementation in multiple sclerosis – Can be done something more?

Tác giả

José-Carlos Tutor.

20. Why is running a marathon like giving birth? The possible role of oxytocin in the underestimation of the memory of pain induced by labor and intense exercise

Tác giả

Dominika Farley, Łukasz Piszczek, Przemysław Bąbel.

20. Glaucoma as a dangerous interplay between ocular fluid and cerebrospinal fluid

Tác giả

Peter Wostyn.

20. Brain wave disturbance and cognitive impairment after CPR

Tác giả

Yahya Jand, Mohammad Reza Raoufy, Ahmad Reza Dehpour.

20. Migraine associated with gastrointestinal disorders: A pathophysiological explanation

Tác giả

Majid Talafi Noghani, Hasan Namdar.

20. ATP in red blood cells as biomarker for sepsis in humans

Tác giả

Yixian Li, Juan Zhou, Ian Burkovskiy, Pollen Yeung, Christian Lehmann.

20. Congenital simple hamartoma of the retinal pigment epithelium: What is the probable cause?

Tác giả

Amar Pujari, Divya Agarwal, Rohan Chawla, Vishnu Todi, Atul Kumar.

20. Spatial gradient of bicoid is well explained by Birnbaum-Saunders distribution

Tác giả

Hossein Hassani, Mahdi Kalantari, Zara Ghodsi.

21. Jacqueline du Pré and her alternative diagnosis

Tác giả

Takahiro Mezaki, Kanako Namekawa.

21. Reduced melatonin synthesis in pregnant night workers: Metabolic implications for offspring

Tác giả

P.A. Nehme, F. Amaral, A. Lowden, D.J. Skene, C.R.C. Moreno.

21. Yin and Yang: Why did evolution implement and preserve the circadian rhythmicity?

Tác giả

B. Poljsak, S. Ribarič, I. Milisav.

21. Neutrophil/lymphocyte ratio: Can a non-specific marker of inflammation helps to confirm the inflammatory hypothesis of the serious mental diseases? A case-control study

Tác giả

J.F. Olcina Rodríguez, J. Díaz Fernández, Nieves Orta Mira, E. López-Briz, Fernando Gómez-Pajares.

21. Love is a physiological motivation (like hunger, thirst, sleep or sex)

Tác giả

Enrique Burunat.

21. CRISPR/Cas 9 system for the treatment of dilated cardiomyopathy: A hypothesis related to function of a MAP kinase

Tác giả

Jéssica Olivaes, Martín Hernán Bonamino, Melissa Medeiros Markoski.

21. Preclinical signs of Parkinson's disease: A possible association of Parkinson's disease with skin and hair features

Tác giả

Neringa Jucevičiūtė, Indrė Banaitytė, Antanas Vaitkus, Renata Balnytė.

21. Assisted jumping: A possible method of incorporating high-velocity exercise in older populations

Tác giả

James J. Tufano.

21. Tea polyphenols as multi-target therapeutics for Alzheimer’s disease: An in silico study

Tác giả

Muhammed Khairujjaman Mazumder, Shuvasish Choudhury.

21. Notch signaling pathway mediates alveolar bone resorption in apical periodontitis

Tác giả

Aleksandar Jakovljevic, Maja Miletic, Nadja Nikolic, Katarina Beljic-Ivanovic, Jelena Milasin.

21. Association of silicone breast implants and acute renal allograft rejection

Tác giả

N. Basic-Jukic, M. Ratkovic, D. Radunovic, Z. Kastelan.

21. Transferred maternal fatty acids stimulate fetal adipogenesis and lead to neonatal and adult obesity

Tác giả

Andrew J. Szabo.

22. Primal health research in the age of epigenetic clocks

Tác giả

Sylvie Odent, Michel Odent.

22. Toward a cure for lumbar spinal stenosis: The potential of interspinous process decompression

Tác giả

Jon E. Block, William F. Lavelle, Pierce D. Nunley.

22. Refined carbohydrates, phenotypic plasticity and the obesity epidemic

Tác giả

Patrick Bradley.

22. Hypothesis: Compulsive hoarding as an atavism

Tác giả

Sandro René Pinto de Sousa Miguel, Rodrigo Ligabue-Braun.

22. Thiamin and protein folding

Tác giả

Derrick Lonsdale.

22. Cimetidine as a novel adjunctive treatment for early stage Lyme disease

Tác giả

Justin Shemenski.

22. Genetic reprogramming of somatic cells into neuroblasts through a co-induction of the doublecortin gene along the Yamanaka factors: A promising approach to model neuroregenerative disorders

Tác giả

Mahesh Kandasamy, Ajisha Yesudhas, G.P. Poornimai Abirami, Risna Kanjirassery Radhakrishnan, Ludwig Aigner.

22. The near-death experience (NDE) as an inherited predisposition: Possible genetic, epigenetic, neural and symbolic mechanisms

Tác giả

ames Lake.

22. Using extracellular calcium concentration and electric pulse conditions to tune platelet-rich plasma growth factor release and clotting

Tác giả

Allen L. Garner, Andrew L. Frelinger, Anja J. Gerrits, Thomas Gremmel, V. Bogdan Neculaes.

22. 3D in vitro cancerous tumor models: Using 3D printers

Tác giả

Zahra Zahedi-Tabar, Shadab Bagheri-Khoulenjani, Hamid Mirzadeh, Saeid Amanpour.

22. Physiology of aging

Tác giả

Jung Y. Hahr.

22. A hypothetical explanatory sensorimotor model of bilateral limb interference

Tác giả

Michihiro Osumi, Masahiko Sumitani, Yuko Otake, Shu Morioka.

23. A model of human endogenous retrovirus (HERV) activation in mental health and illness

Tác giả

Turhan Canli.

23. Discovery of novel natural flavonoids as potent antiviral candidates against hepatitis C virus NS5B polymerase

Tác giả

Farideh Badichi Akher, Abdolkarim Farrokhzadeh, Pritika Ramharack, Letitia Shunmugam, Mahmoud E.S. Soliman.

23. Rethinking the pragmatic systems biology and systems-theoretical biology divide: Toward a complexity-inspired epistemology of systems biomedicine

Tác giả

Srdjan Kesić.

23. Antenatal study of the Heschl’s gyrus: The first step to understanding prenatal learning

Tác giả

C. López Ramón y Cajal.

23. Penehyclidine hydrochloride on postoperatively cognitive function

Tác giả

X. Hongyu, W. Qingting, S. Xiaoling, Z. Liwu, L. Xin.

23. Corrigendum to ‘Sarcopenia as a potential cause of chronic hyponatremia in the elderly’ [Med. Hypotheses, 127 (2019) 46–48]

Tác giả

Victoria Bertoni, Chiara Nicoletti, Braian M. Beker, Carlos G. Musso.

23. Genomic mosaicism: A neglected factor that promotes variability in asthma diagnosis

Tác giả

Thiago de Bittencourt Buss, Leonardo Mroginski, Gabriel Moojen de Jesus, Sofia Forcellini, José Eduardo Vargas.

23. Does integrated cognitive and balance (dual-task) training improve balance and reduce falls risk in individuals with cerebellar ataxia?

Tác giả

Stanley Winser, Marco Y.C. Pang, Jessica S. Rauszen, Anne Y.Y. Chan, Susan L. Whitney.

23. Development of a semi-quantitative tear film based method for public screening of diabetes mellitus

Tác giả

Brijesh Takkar, Sukhes Mukherjee, Ramesh Chand Chauhan, Pradeep Venkatesh.

23. Aging, metabolic acidosis and renal failure: Interactive accelerating processes

Tác giả

L.A. Frassetto, A. Sebastian.

23. Cerebral arteriovenous malformation venous stenosis is associated with hemodynamic changes at the draining vein-venous sinus junction

Tác giả

Murad Alqadi, Denise Brunozzi, Andreas Linninger, Sepideh Amin-Hanjani, Ali Alaraj.

23. The cause-effect relationship between bone loss and Alzheimer’s disease using statistical modeling

Tác giả

Natalia Loskutova, Amber S. Watts, Jeffrey M. Burns.

24. The effect of supplementation with Scutellaria baicalensis on hepatic function

Tác giả

Basant K. Puri, Nikita White, Jean A. Monro.

24. Inguinal microbiome in patients undergoing an endovascular aneurysm repair: Application of next-generation sequencing of the 16S-23S rRNA regions

Tác giả

B.P. Vierhout, A. Ott, I. Kruithof, G. Wisselink, R.A. Pol.

24. Corrigendum to “Role of leptin as a biomarker for early detection of renal cell carcinoma? No evidence from a systematic review and meta-analysis” [Med. Hypotheses 129 (2019) 1–6]

Tác giả

Komathi Perumal, Weng Kit Huin, Ning Yi Yap, Teng Aik Ong, Retnagowri Rajandram.

24. Mirror self recognition as a product of forward models; implications for delusions of body image and visual neglect

Tác giả

Sean O'Connor.

24. The impact of the ambiguous definition of “month” on pharmacotherapy

Tác giả

Unax Lertxundi, Rafael Hernandez, Juan Medrano.

24. Toll-like receptor 4 (TLR4) as a possible pathological mechanism in hyperglycemia-associated testicular dysfunction

Tác giả

Huda Naas, Amanda Almeida de Oliveira, Tatiana Karpova, Kenia Pedrosa Nunes.

24. Could blood products obtained from patients with familial Mediterranean fever have beneficial or harmful effects?

Tác giả

Salih Kavukcu, Alper Soylu.

24. Possible role of PPAR-γ and COX-2 receptor modulators in the treatment of Non-Small Cell lung carcinoma

Tác giả

V.V.V. Ravi Kiran Ammu, Kusuma Kumari Garikapati, Praveen T. Krishnamurthy, Pavan Kumar Chintamaneni, Sai Kiran S.S. Pindiprolu.

24. Neuromuscular taping reduces blood pressure in systemic arterial hypertension

Tác giả

David Blow, Claudia Celletti, Carmine Berlingieri, Filippo Camerota.

24. Captive uterus syndrome: An unrecognized complication of cesarean sections?

Tác giả

I. Hardy, S. Rousseau.

25. Issues in the interpretation of serum endothelin levels in preeclampsia

Tác giả

Charles G. Coffey.

25. Could there be any merit in lumping primary open-angle glaucoma, idiopathic intracranial hypertension and Meniere’s disease into a novel and discrete category of fluid tension disorders?

Tác giả

A. Moodley, K Van Der Meyden.

25. Elevated plasma RANTES in fibrodysplasia ossificans progressiva – A novel therapeutic target?

Tác giả

Lovorka Grgurević, Ruđer Novak, Vladimir Trkulja, Lejla Ferhatović Hamzić, Marija Santini.

25. How to obtain severe hypoglycemia without causing brain or cardiac damage

Tác giả

Martina Baiardo Redaelli, Alberto Zangrillo, Vanesa Gregorc, Fabio Ciceri, Giovanni Landoni.

25. Dialysis disequilibrium syndrome revisited: Feeling “Disequilibrated” due to inner ear dyshomeostasis?

Tác giả

Chang-Hee Kim, Jung Eun Shin, Jung Hwan Park.

25. Aging: An evolutionary competition between host cells and mitochondria Dun-Xian Tan.

Tác giả

Dun-Xian Tan.

25. Helminth therapy for autism under gut-brain axis- hypothesis

Tác giả

Celia Arroyo-López.

25. A hypothetical method for calculation of the access point, direction angle and access angle for percutaneous nephrolithotomy

Tác giả

Murat Akand, Ahmet Buyukaslan, Sema Servi, Levent Civcik.

25. Collagenous colitis development occurs after long standing mucosal healing in IBD with TNF-α inhibitors, and could be due to exaggerated healing response from excess TNF-α inhibition

Tác giả

Rahoma E. Saad, Rima Shobar, Ece A. Mutlu.

25. Diets with customary levels of fat from plant origin may reverse coronary artery disease

Tác giả

Albert Sanchez, Alfredo Mejia, Joanie Sanchez, Eric Runte, Randall L. Bivens.

26. Antitumor effects of the electromagnetic resonant frequencies derived from the 1H NMR spectrum of Ph3Sn(Mercaptonicotinic)SnPh3 complex

Tác giả

Ioannis I. Verginadis, Spyridon Ch. Karkabounas, Yannis V. Simos, Anastasia P. Velalopoulou, Angelos M. Evangelou.

26. Toward a closed-loop deep brain stimulation in Parkinson’s disease using local field potential in parkinsonian rat model

Tác giả

Sana Amoozegar, Mohammad Pooyan, Mehrdad Roughani.

26. The sour side of vitamin C might mediate neuroprotective, anticonvulsive and antidepressant-like effects

Tác giả

Udo Bonnet.

26. Parent-child interaction and stimulation in early life can be related to caries in primary dentition? Hypotheses from a life-course approach

Tác giả

Francine dos Santos Costa, Bernardo Antonio Agostini, Helena Silveira Schuch, Marcos Britto Correa, Flávio Fernando Demarco.

26. Using titanium mesh to replace the bone flap during decompressive craniectomy: A medical hypothesis

Tác giả

Junhua Ye, Wenbo Zhang, Min Ye.

26. Hypothesis: Regulation of neuroplasticity may involve I-motif and G-quadruplex DNA formation modulated by epigenetic mechanisms

Tác giả

German Todorov, Catarina Cunha.

26. PRE-binding protein of Plasmodium falciparum is a potential candidate for vaccine design and development: An in silico evaluation of the hypothesis

Tác giả

Bijara Devi Sanasam, Sanjeev Kumar.

26. A unifying hypothesis for delirium and hospital-acquired weakness as synaptic dysfunctions

Tác giả

Adrian A. Jarquin-Valdivia, Reagan J. Major.

26. Can immunization with Bacillus Calmette-Guérin (BCG) protect against Alzheimer’s disease?

Tác giả

Ofer N. Gofrit, Herve Bercovier, Benjamin Y. Klein, Irun R. Cohen, Charles L. Greenblatt.

26. Early-life inflammation pathways trigger a cascade leading to development of atherosclerotic plaque through the “butterfly effect” – An hypothesis

Tác giả

M. Kowara, K. Kasarełło, K. Czarzasta, G. Opolski, A. Cudnoch-Jędrzejewska.

27. Melatonin: A hypothesis regarding its use to treat Wilson disease

Tác giả

Ramaswamy Sharma, Russel J. Reiter, Qiang Ma.

27. Consideration of gravity as a possible etiological factor in amyotrophic lateral sclerosis

Tác giả

Tetsuya Akaishi, Toshiyuki Takahashi, Michiaki Abe, Masashi Aoki, Tadashi Ishii.

27. Can intravesical application of paracetamol benefit the chemotherapy treatment of bladder cancer?

Tác giả

Ersoy Öksüz, Muhammet Serdar Buğday.

27. The hypothetical relation between the degree of stress and auditory cortical evoked potentials in tinnitus sufferers

Tác giả

Abdollah Moossavi, Maryam Sadeghijam, Mahdi Akbari.

27. M2-like cells from the macrophage lineage might play a central role in closure of the embryonic neural tube

Tác giả

Janice Block.

27. An action planning mechanism hypothesis on Broca’s aphasia

Tác giả

Ciro Antunes Medeiros.

27. Nonmelanoma skin cancer killed Mattia Preti (1613–1699), the “Calabrian Knight”

Tác giả

A. Perciaccante, D. Lippi, V. Asensi, A. Coralli, R. Bianucci.

27. Asymmetric sacroiliac joint anatomy in partial lumbosacral transitional variations: Potential impact on clinical testing in sacral dysfunctions

Tác giả

Niladri Kumar Mahato.

27. The Perception Approach: Level of Observer Variability Rating and Fusion Diagnoses

Tác giả

Benedikt Martin, Bruno Märkl.

27. Macrophages hold the key to cancer’s inner sanctum

Tác giả

Gerald L. Wolf.

28. Is “normal tension glaucoma” glaucoma?

Tác giả

Ning Fan, Junkai Tan, Xuyang Liu.

28. Low intensity blood flow restriction exercise: Rationale for a hypoalgesia effect

Tác giả

Luke Hughes, Stephen David Patterson.

28. Is it possible to detect cerebral dominance via EEG signals by using deep learning?

Tác giả

Suat Toraman, Seda Arslan Tuncer, Ferhat Balgetir.

28. Hydrocephalus associated with multiple Tarlov cysts

Tác giả

Mieke Hulens, Wim Dankaerts, Ricky Rasschaert, Frans Bruyninckx, Peter De Mulder.

28. Tetra-linoleoyl cardiolipin depletion plays a major role in the pathogenesis of sarcopenia

Tác giả

Richard D. Semba, Ruin Moaddel, Pingbo Zhang, Christopher E. Ramsden, Luigi Ferrucci.

28. The role of progesterone/estradiol ratio in exploring the mechanism of late follicular progesterone elevation in low ovarian reserve women

Tác giả

Johnny S. Younis.

28. Endometriosis treatment with shock waves: A novel approach

Tác giả

E. Melki.

28. Lateral epicondylalgia: A primary nervous system disorder

Tác giả

Diego Bordachar.

28. Volatility and fluctuations in preferences for Red, Yellow and Blue colours are indicators of personality traits and biological status

Tác giả

George John.

29. Will the polyphenol and adapalene combination be a good strategy on acne vulgaris?

Tác giả

S.K. Janani, Raman Sureshkumar, Sai Surya Nikitha Upadhyayula, Chenmala Karthika, C. Vasanthi.

29. A diet rich in taurine, cysteine, folate, B12 and betaine may lessen risk for Alzheimer’s disease by boosting brain synthesis of hydrogen sulfide

Tác giả

Mark F. McCarty, James H. O'Keefe, James J. DiNicolantonio.

29. Patient characteristics and analgesic efficacy of antiviral therapy in postherpetic neuralgia

Tác giả

Yao-Tsung Lin, Li-Kai Wang, Kuo-Chuan Hung, Zhi-Fu Wu, Jen-Yin Chen.

29. Epithelial-mesenchymal transition induced by MyoD inhibits growth of high metastatic colorectal cancer

Tác giả

Huapeng Sun, Aixia Tian, Jin Zhang, Xiaofeng Liao, Na Zhang.

29. Positive selection of type 2 diabetes genotypes – the glycaemic threshold hypothesis

Tác giả

P.H. Wise.

29. Alzheimer’s disease might depend on enabling pathogens which do not necessarily cross the blood-brain barrier

Tác giả

Janice Block.

29. Magnesium sulfate – An effective agent could delay the progression of fulminant malignant hyperthermia

Tác giả

Xuebing Xu.

29. Obesity and inactivity, not hyperglycemia, cause exercise intolerance in individuals with type 2 diabetes: Solving the obesity and inactivity versus hyperglycemia causality dilemma

Tác giả

Matthew T. Lewis, Heidi L. Lujan, Anne Tonson, Robert W. Wiseman, Stephen E. DiCarlo.

29. Retroperitoneal fibrosis. Steroid treatment response seems to depend on its association to IgG4 related disease

Tác giả

Andrea Soriano Rios, Humberto Paredes, Jorge Hernández-Calleros, Luis Uscanga-Domínguez, Mario Peláez-Luna.

30. Enhancing the efficacy of 5-HT uptake inhibitors in the treatment of attention deficit hyperactivity disorder

Tác giả

Timothy B. Riley, Paul G. Overton.

30. A new approach for brain tumor diagnosis system: Single image super resolution based maximum fuzzy entropy segmentation and convolutional neural network

Tác giả

Eser Sert, Fatih Özyurt, Akif Doğantekin.

30. Gulf War Illnesses are autoimmune conditions caused by the direct effect of the nerve gas prophylaxis drug (pyridostigmine bromide) on anergic immune system lymphocytes

Tác giả

J.I. Moss.

30. A hypothesis regarding how sleep can calibrate neuronal excitability in the central nervous system and thereby offer stability, sensitivity and the best possible cognitive function

Tác giả

J.H. Sture Hansson.

30. Phosphodiesterase 5 inhibitors and adrenal incidentalomas

Tác giả

Ioannis Ilias, Lina Zabuliene.

30. The vitamin D positive feedback hypothesis of inflammatory bowel diseases

Tác giả

Z. Linneman, C. Reis, K. Balaji, J. Moore, S. Braude.

30. Prolactin and Prolactin-inducible protein (PIP) in the pathogenesis of primary acquired nasolacrimal duct obstruction (PANDO)

Tác giả

Mohammad Javed Ali, Friedrich Paulsen.

30. Urinary volatile metabolomics as a viable alternative diagnostic tool for polycystic ovary syndrome: An exploratory hypothesis

Tác giả

Devaraj Sankarganesh, Udhayaraj Suriyakalaa, Rajamanickam Ramachandran, Shanmugam Achiraman, Jayaraman Angayarkanni.

30. What decides the nature of extraocular muscle injury? The probable mechanism of flap tear and rupture

Tác giả

Amar Pujari, Rohit Saxena, Pradeep Sharma, Swati Phuljhele.

30. Functional duality of ethanol on cancer

Tác giả

Shanshan An, Xiaoxia Li, Man Tang, Sirui Yan, Qiuyun Liu.

31. Enhancing the efficacy of 5-HT uptake inhibitors in the treatment of attention deficit hyperactivity disorder

Tác giả

Timothy B. Riley, Paul G. Overton.

31. CV RISK – A new relative cardiovascular risk score

Tác giả

Dumitru Zdrenghea, Gabriel Guşetu, Mihnea Zdrenghea, Gabriel Cismaru, Dana Pop.

31. Exogenous intrapleural injection of interleukin-27 may improves outcome and prognosis in patients with tuberculous pleural effusion

Tác giả

Yiling Gan, Shuliang Guo, Youming Zhu, Jie Jiang, Yuanrong Tan.

31. Treatment resistance in major depression is correlated with increased plasma levels of neurofilament light protein reflecting axonal damage

Tác giả

Susanne Spanier, Hannah M. Kilian, Dora M. Meyer, Thomas E. Schlaepfer.

31. Is Interleukin-38 a key player cytokine in atherosclerosis immune gene therapy?

Tác giả

Abdolreza Esmaeilzadeh, Shabnam Pouyan, Maryam Erfanmanesh.

31. Carbonic anhydrase enzymes: Likely targets for inhalational anesthetics

Tác giả

H.Z. Ozsoy.

31. Intramuscular injection of collagenase clostridium histolyticum may decrease spastic muscle contracture for children with cerebral palsy

Tác giả

Jason J. Howard, James S. Huntley, H. Kerr Graham, Walter L. Herzog.

32. A potential role of cyclin-dependent kinase inhibitor 1 (p21/WAF1) in the pathogenesis of endometriosis: Directions for future research

Tác giả

Nikolaos Zarkadoulas, Vasilios Pergialiotis, Dimitrios Dimitroulis, Konstantinos Stefanidis, Konstantinos Kontzoglou.

32. Hyperbaric oxygen toxicity in brain: A case of hyperoxia induced hypoglycemic brain syndrome

Tác giả

David F. Wilson, Franz M. Matschinsky.

32. Monoacylglycerol lipase inhibition as potential treatment for interstitial cystitis

Tác giả

Anu Chinnadurai, Geraint Berger, Ian Burkovskiy, Juan Zhou, Christian Lehmann.

32. Activated glycine receptors may decrease endosomal NADPH oxidase activity by opposing ClC-3-mediated efflux of chloride from endosomes

Tác giả

Mark F. McCarty, Simon Iloki-Assanga, Lidianys Maria Lewis Lujan, James J. DiNicolantonio.

32. Hypothesis: Folklore perpetuated expression of moon-associated bipolar disorders in anecdotally exaggerated werewolf guise

Tác giả

Thomas C. Erren, Philip Lewis.

33. Radiotherapy dose painting by circadian rhythm based radiomics

Tác giả

Hamid Abdollahi.

33. Vascular bundle transplantation combined with porous bone substituted scaffold for the treatment of early-stage avascular necrosis of femoral head

Tác giả

Bo Li, Minghui Yang, Lingjia Yu.

33. Hypothesis: Metabolic targeting of 5-aminolevulinate synthase by tryptophan and inhibitors of heme utilisation by tryptophan 2,3-dioxygenase as potential therapies of acute hepatic porphyrias

Tác giả

Abdulla A.-B. Badawy.

33. Was the Last Ice Age dusty climate instrumental in spreading of the three “Celtic” diseases (hemochromatosis, cystic fibrosis and palmar fibromatosis)?

Tác giả

Sven Kurbel.

34. Corrigendum to: “Does high-dose gestational folic acid increase the risk for autism? The birth order hypothesis” [Medical Hypotheses 132 (2019) 109350]

Tác giả

Gideon Koren, Sarah Moser-Sharman.

34. Cytosolic non-vesicular dopamine accumulation as the predominant mechanism for developing non-DOPA responsive parkinsonism in late-stage Huntington disease

Tác giả

Rafael Vincent M. Manalo.

34. Unusual preference of blue clothes in children with congenital cyanotic heart disease (CCHD)

Tác giả

Shagun Shah, Chandrahas T. Deshmukh.

34. May probable cause of hypertension in hypertensive disorders of pregnancy be over expressing tyramine depending deterioration of microbiota composition

Tác giả

Suleyman Aydin, Sefer Ustebay, Yakup Baykus, Rulin Deniz.

35. Tamoxifen and Sulphoraphane for the breast cancer management: A synergistic nanomedicine approach

Tác giả

Bharti Mangla, Yub Raj Neupane, Archu Singh, Kanchan Kohli.

35. Systemic subclinical lymphedema due to obesity as the cause of clinical lymphedema: A new concept

Tác giả

José Maria Pereira de Godoy.

35. Transfused trauma patients have better outcomes when transfused with blood components from young donors

Tác giả

Francesco Amico, Gabrielle Briggs, Zsolt J. Balogh.

36. Is selective protein adsorption on biomaterials a viable option to promote periodontal regeneration?

Tác giả

Ludovica Parisi, Andrea Toffoli, Beatrice Mozzoni, Federico Rivara, Guido M. Macaluso.

36. Physiotherapy in oral submucous fibrosis can increase the malignant potential

Tác giả

Sachin C. Sarode, Gargi S. Sarode, Amol R. Gadbail, Shailesh Gondivkar, Shankargouda Patil.

36. Pathomechanism of iris sphincter tear

Tác giả

Amar Pujari, Divya Agarwal, Aswini Kumar Behera, Karthika Bhaskaran, Namrata Sharma.

37. Pulmonary lymphangioleiomyomatosis: A proposed state of neoplastic senescence

Tác giả

Charles M. Lombard.

37. Versatility of fuzzy logic in chronic diseases: A review

Tác giả

Sunny Thukral, Vijay Rana.

38. Corrigendum to “Hypothesis: Metabolic targeting of 5-aminolevulinate synthase by tryptophan and inhibitors of heme utilisation by tryptophan 2,3-dioxygenase as potential therapies of acute hepatic porphyrias” [Med. Hypotheses 131 (2019) 109314]

Tác giả

A.A.-B. Badawy.

38. The role of endocrine disruptors in ocular surface diseases

Tác giả

Regina C.N. Pontelli, Marília C.O. Souza, Marina Z. Fantucci, Mônica de Andrade, Eduardo M. Rocha.

39. A mechanistic theory explaining hyperferritinaemia in haemophagocytic lymphohistiocytosis

Tác giả

J. Stroud.

40. Heat transfer, entropy and time perception: Toward finding a possible relation between subjective and objective time

Tác giả

Amir Hossein Ghaderi.

41. Is lipoxin A4 an effective treatment on fat embolism syndrome by attenuating pro-inflammatory response?

Tác giả

Hui Zhang, Aizhong Wang, Tao Xu, Junfeng Zhang, Hong Xie.

42. Did Blaise Pascal have autism spectrum disorder and a genetic predisposition for skull deformities?

Tác giả

R. Bianucci, A. Perciaccante, D. Lippi, P. Charlier, O. Appenzeller.

43. Time and geographic clustering of adult patients with unilateral idiopathic sudden sensorineural hearing loss

Tác giả

Sapideh Gilani, Jennifer J. Shin.

44. The potential role of vascular alterations and subsequent impaired liver blood flow and hepatic hypoxia in the pathophysiology of non-alcoholic steatohepatitis

Tác giả

D. van der Graaff, W.J. Kwanten, S.M. Francque.

45. Are the permanent sequelae of Crohn’s disease a failure to treat the gastrointestinal microbiota?

Tác giả

Gilles R.G. Monif.

46. Presence of kynurenic acid in alcoholic beverages – Is this good news, or bad news?

Tác giả

Monika Turska, Rafał Rutyna, Maciej Paluszkiewicz, Paulina Terlecka, Tomasz Plech.

47. Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: A novel evidence-based medical hypothesis

Tác giả

Salah Mohamed El Sayed, Hussam Baghdadi, Nagwa Sayed Ahmed, Hamdi H. Almaramhy, Moutasem Salih Aboonq.

48. Prenatal identification of autism propensity

Tác giả

Gary Steinman.