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Bioorganic Chemistry
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Volume 90, September 2019, Hidden issue
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1. Editorial Board
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2. Issue TOC
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3. Discovery of novel indole-based aroylhydrazones as anticonvulsants: Pharmacophore-based design
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Violina T. Angelova, Miroslav Rangelov, Nadezhda Todorova, Miroslav Dangalov, ... Jana Tchekalarova.
4. Novel cytisine derivatives exert anti-liver fibrosis effect via PI3K/Akt/Smad pathway
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Sheng Tang, Yinghong Li, Yunyang Bao, Zhiting Dai, ... Danqing Song.
5. Green synthesis of selenium-N-heterocyclic carbene compounds: Evaluation of antimicrobial and anticancer potential
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Amna Kamal, Mansoureh Nazari V., Muhammad Yaseen, Muhammad Adnan Iqbal, ... Haq Nawaz Bhatti.
6. Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
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Cibele Nicolaski Pedron, Iris Araújo, Pedro Ismael da Silva Junior, Fernanda Dias da Silva, ... Vani Xavier Oliveira Junior.
7. Improving the catalytic efficiency of aldo-keto reductase KmAKR towards t-butyl 6-cyano-(3R,5R)-dihydroxyhexanoate via semi-rational design
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Han Yu, Shuai Qiu, Feng Cheng, Ying-Nan Cheng, ... Yu-Guo Zheng.
8. Cytotoxic and neuroprotective activities of constituents from Alternaria alternate, a fungal endophyte of Psidium littorale
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Jian Xu, Yun-Wei Hu, Wei Qu, Ming-Hua Chen, ... Jie Zhang.
9. Probing the binding mechanism of capecitabine to human serum albumin using spectrometric methods, molecular modeling, and chemometrics approach
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S. Fatemeh Mousavi, Mohammad Hossein Fatemi.
10. New phenolic Mannich bases with piperazines and their bioactivities
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Halise Inci Gul, Mehtap Tugrak, Mustafa Gul, Sertac Mazlumoglu, ... Claudiu T. Supuran.
11. Investigation of potent inhibitors of cholinesterase based on thiourea and pyrazoline derivatives: Synthesis, inhibition assay and molecular modeling studies
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Amara Mumtaz, Abdul Majeed, Sumera Zaib, Shafiq Ur Rahman, ... Jamshed Iqbal.
12. Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase
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Josephine M. Gießel, Immo Serbian, Anne Loesche, René Csuk.
13. Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvement
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Gianfranco Fontana, Maurizio Bruno, Monica Notarbartolo, Manuela Labbozzetta, ... Sergio Rosselli.
14. Exploiting the 7-methylimidazo[1,5-a]pyrazin-8(7H)-one scaffold for the development of novel chemical inhibitors for Bromodomain and Extraterminal Domain (BET) family
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Yifei Yang, Pan Chen, Leilei Zhao, Fangqing Zhang, ... Jinpei Zhou.
15. Design, synthesis of celecoxib-tolmetin drug hybrids as selective and potent COX-2 inhibitors
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Khaled R.A. Abdellatif, Eman K.A. Abdelall, Madlen B. Labib, Wael A.A. Fadaly, Taha H. Zidan.
16. Novel Pyrazoloquinolin-2-ones: Design, synthesis, docking studies, and biological evaluation as antiproliferative EGFR-TK inhibitors
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Mohammed A.I. Elbastawesy, Ashraf A. Aly, Mohamed Ramadan, Yaseen A.M.M. Elshaier, ... Gamal El-Din A Abuo-Rahma.
17. Protective effect of hypoxylonol C and 4,5,4′,5′-tetrahydroxy-1,1′-binaphthyl isolated from Annulohypoxylon annulatum against streptozotocin-induced damage in INS-1 cells
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Dahae Lee, Pilju Choi, Buyng Su Hwang, Taejung Kim, ... Jungyeob Ham.
18. Facile synthesis and antimicrobial activity of CdS-Ag2S nanocomposites
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Tahir Iqbal, Faisal Ali, N.R. Khalid, M. Bilal Tahir, Mohsin Ijaz.
19. Identification of nicotinamide aminonaphthyridine compounds as potent RET kinase inhibitors and antitumor activities against RET rearranged lung adenocarcinoma
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Modi Wang, N. Naganna, Herman O. Sintim.
20. Isolation and characterization of three pairs of indolediketopiperazine enantiomers containing infrequent N-methoxy substitution from the marine algal-derived endophytic fungus Acrostalagmus luteoalbus TK-43
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Jin Cao, Xiao-Ming Li, Ling-Hong Meng, Belma Konuklugil, ... Bin-Gui Wang.
21. Anticancer properties of N-alkyl-2, 4-diphenylimidazo [1, 2-a] quinoxalin-1-amine derivatives; kinase inhibitors
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Zahra Rezaei, Mir Mahdi Didehvar, Mohammad Mahdavi, Homa Azizian, ... Mohsen Amini.
22. Ultrasound-assisted synthesis of novel chalcone, heterochalcone and bis-chalcone derivatives and the evaluation of their antioxidant properties and as acetylcholinesterase inhibitors
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Efraín Polo, Nicol Ibarra-Arellano, Luis Prent-Peñaloza, Alejandro Morales-Bayuelo, ... Margarita Gutiérrez.
23. Synthesis, molecular docking and kinetic studies of novel quinolinyl based acyl thioureas as mushroom tyrosinase inhibitors and free radical scavengers
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Muhammad Naeem Mustafa, Aamer Saeed, Pervaiz Ali Channar, Fayaz Ali Larik, ... Sung-Yum Seo.
24. Synthesis, modeling and biological evaluation of some pyrazolo[3,4-d]pyrimidinones and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones as anti-inflammatory agents
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Gina N. Tageldin, Tamer M. Ibrahim, Salwa M. Fahmy, Hayam M. Ashour, ... Ibrahim M. Labouta.
25. New potent antifungal triazole alcohols containing N-benzylpiperazine carbodithioate moiety: Synthesis, in vitro evaluation and in silico study
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Yaser Mahmoudi, Hamid Badali, Seyedeh Mahdieh Hashemi, Mahsa Ansari, ... Saeed Emami.
26. Antibacterial activity of 3,3′-dihydroxycurcumin (DHC) is associated with membrane perturbation
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Carlos R. Polaquini, Luana G. Morão, Ana C. Nazaré, Guilherme S. Torrezan, ... Luis O. Regasini.
27. A competent synthesis and efficient anti-inflammatory responses of isatinimino acridinedione moiety via suppression of in vivo NF-κB, COX-2 and iNOS signaling
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Govindasami Periyasami, Paulrayer Antonisamy, Karthikeyan Perumal, Antony Stalin, ... Asma A. Alothman.
28. One-step synthesis of methylene-bridged bis-carbazole and evaluation of its antitumor activity and G-quadruplex DNA binding property
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Gang Li, Haodong Tang, Chuanfeng Liu, Xiaoyu Liao, ... Peng Yang.
29. Synthesis, anti-diabetic evaluation and molecular docking studies of 4-(1-aryl-1H-1, 2, 3-triazol-4-yl)-1,4-dihydropyridine derivatives as novel 11-β hydroxysteroid dehydrogenase-1 (11β-HSD1) inhibitors
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E. Praveenkumar, Nirmala Gurrapu, Prashanth Kumar Kolluri, Vishwanadham Yerragunta, ... N.J.P. Subhashini.
30. Discovery of aromatic amides with triazole-core as potent reversal agents against P-glycoprotein-mediated multidrug resistance
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Qianqian Qiu, Jilan Zhu, Qiutong Chen, Ziqian Jiang, ... Xiaojuan Xu.
31. Extraction, isolation and in vitro evaluation of affinisine from Tabernaemontana catharinensis in human melanoma cells
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Pauline Fagundes Rosales, Adriana Gower, Martha Lucia Ruiz Benitez, Bruna Silveira Pacheco, ... Sidnei Moura.
32. Human neutrophil elastase (HNE) inhibitory polyprenylated acylphloroglucinols from the flowers of Hypericum ascyron
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Zuo Peng Li, Jeong Yoon Kim, Yeong Jun Ban, Ki Hun Park.
33. 6-Substituted purines as ROCK inhibitors with anti-metastatic activity
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Jiří Voller, Lenka Zahajská, Lucie Plíhalová, Jana Jeřábková, ... Miroslav Strnad.
34. Muscle extract of Arothron immaculatus regulates the blood glucose level and the antioxidant system in high-fat diet and streptozotocin induced diabetic rats
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Karunanidhi Kaleshkumar, Rajendran Rajaram, Nambirajan Gayathri, Thilagar Sivasudha, ... Parasuraman Padmanabhan.
35. Dihydrofolate reductase inhibition effect of 5-substituted pyrido[2,3-d]pyrimidines: Synthesis, antitumor activity and molecular modeling study
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Ola A. Abdelaziz, Walaa M. El Husseiny, Khalid B. Selim, Hassan M. Eisa.
36. Synthesis and in vitro anti-tumor activity of carboranyl levodopa
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Yinghuai Zhu, Yongxiang Lin, Narayan S. Hosmane.
37. Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer’s disease
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Gopichand Gutti, Devendra Kumar, Pankaj Paliwal, Ankit Ganeshpurkar, ... Sushil Kumar Singh.
38. Bioactive aporphine alkaloids from the stems of Dasymaschalon rostratum
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Zhangxin Yu, Changri Han, Xiaoping Song, Guangying Chen, Jinxiong Chen.
39. Discovery of a novel DNA binding agent via design and synthesis of new thiazole hybrids and fused 1,2,4-triazines as potential antitumor agents: Computational, spectrometric and in silico studies
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Marwa H. El-Wakil, Amira F. El-Yazbi, Hayam M.A. Ashour, Mounir A. Khalil, ... Ibrahim M. Labouta.
40. Search for multifunctional agents against Alzheimer’s disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
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Jakub Jończyk, Krzysztof Lodarski, Marek Staszewski, Justyna Godyń, ... Marek Bajda.
41. Design, synthesis and biological evaluation of novel thieno[3,2-d]pyrimidine and quinazoline derivatives as potent antitumor agents
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Hao Hu, Yuhong Dong, Ming Li, Ruxin Wang, ... Yanfang Zhao.
42. 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as inhibitors of full-length RORγt
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Chuyu Lao, Xiaoqing Zhou, Huanpeng Chen, Fengjiao Wei, ... Chuan Bai.
43. Novel 12-hydroxydehydroabietylamine derivatives act as potent and selective butyrylcholinesterase inhibitors
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Anne Loesche, Jana Wiemann, Matthias Rohmer, Wolfgang Brandt, René Csuk.
44. DNA interaction and photodynamic antitumor activity of transition metal mono-hydroxyl corrole
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Yan-Mei Sun, Waseem Akram, Fan Cheng, Ze-Yu Liu, ... Hai-Yang Liu.
45. The green synthesis and molecular docking of novel N-substituted rhodanines as effective inhibitors for carbonic anhydrase and acetylcholinesterase enzymes
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Sinan Bayindir, Cuneyt Caglayan, Muhammet Karaman, İlhami Gülcin.
46. Substituted phenyl[(5-benzyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetates/acetamides as alkaline phosphatase inhibitors: Synthesis, computational studies, enzyme inhibitory kinetics and DNA binding studies
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Zafar Iqbal, Zaman Ashraf, Mubashir Hassan, Qamar Abbas, Erum Jabeen.
47. Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors
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Mehtap Tugrak, Halise Inci Gul, Kenjiro Bandow, Hiroshi Sakagami, ... Claudiu T. Supuran.
48. Triazole substituted metal-free, metallo-phthalocyanines and their water soluble derivatives as potential cholinesterases inhibitors: Design, synthesis and in vitro inhibition study
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Tác giả
Tayfun Arslan, Nezaket Çakır, Turgut Keleş, Zekeriya Biyiklioglu, Murat Senturk.
49. Synthesis, biological evaluation and in silico studies with 4-benzylidene-2-phenyl-5(4H)-imidazolone-based benzenesulfonamides as novel selective carbonic anhydrase IX inhibitors endowed with anticancer activity
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Wagdy M. Eldehna, Mohamed A. Abdelrahman, Alessio Nocentini, Silvia Bua, ... Claudiu T. Supuran.
50. Demethylbellidifolin isolated from Swertia bimaculate against human carboxylesterase 2: Kinetics and interaction mechanism merged with docking simulations
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Tian-Tian Liu, Xiao-Kui Huo, Xiang-Ge Tian, Jia-Hao Liang, ... Xiao-Chi Ma.
51. Synthesis and anticancer activity of bis-benzo[d][1,3]dioxol-5-yl thiourea derivatives with molecular docking study
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Reem A.K. Al-Harbi, Marwa A.M.Sh. El-Sharief, Samir Y. Abbas.
52. Potential chemical transformation of phosphinic acid derivatives and their applications in the synthesis of drugs
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Moaz M. Abdou, Rasha A. El-Saeed.
53. The stilbene derivatives, nucleosides, and nucleosides modified by stilbene derivatives
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Hanna Krawczyk.
54. Synthesis and antitumor activity of three novel ginsenoside M1 derivatives with 3′-ester modifications
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Ke-Ke Li, Xiao-Mei Yan, Zheng-Ning Li, Qiu Yan, Xiao-Jie Gong.
55. Benzoxaboroles as dynamic covalent receptors for bioconjugation and transport of nucleosides and related drugs: Proof of action in HeLa cells
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Cecilia Samaniego Lopez, Jimena H. Martínez, Sofía L. Acebedo, Carla C. Spagnuolo.
56. Identification of chebulinic acid as a dual targeting inhibitor of protein tyrosine phosphatases relevant to insulin resistance
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Sun-Young Yoon, Hyo Jin Kang, Dohee Ahn, Ji Young Hwang, ... Sang J. Chung.
57. (±)-Meliviticines A and B: Rearranged prenylated acetophenone derivatives from Melicope viticina and their antimicrobial activity
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Wei Li, Li Rao, Yu Liu, Qian He, ... Chuan-Rui Zhang.
58. Amino acids conjugated quinazolinone-Schiff’s bases as potential antimicrobial agents: Synthesis, SAR and molecular docking studies
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K.P. Rakesh, H.K. Kumara, B.J. Ullas, J. Shivakumara, D. Channe Gowda.
