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Bioorganic Chemistry
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Volume 84, Pages 1-528 (March 2019), Hidden issue
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1. Editorial Board
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2. Issue TOC
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3. Synthesis and antioxidant activity of new lipophilic dihydropyridines
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Diego da Costa Cabrera, Eduarda Santa-Helena, Heloisa P. Leal, Renata Rodrigues de Moura, ... Marcelo G. Montes D'Oca.
4. Anti-melanogenesis potential of a new series of Morita-Baylis-Hillman adducts in B16F10 melanoma cell line
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Emna Ketata, Haitham Elleuch, Aref Neifar, Wafa Mihoubi, ... Ali Gargouri.
5. An alkali tolerant α-l-rhamnosidase from Fusarium moniliforme MTCC-2088 used in de-rhamnosylation of natural glycosides
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Dhirendra Kumar, Sarita Yadav, Sudha Yadava, K.D.S. Yadav.
6. Immobilized Baliospermum montanum hydroxynitrile lyase catalyzed synthesis of chiral cyanohydrins
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Nisha Jangir, Santosh Kumar Padhi.
7. Synthesis and biological evaluation of new pyrazolone Schiff bases as monoamine oxidase and cholinesterase inhibitors
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Fatih Tok, Bedia Koçyiğit-Kaymakçıoğlu, Begüm Nurpelin Sağlık, Serkan Levent, ... Zafer Asım Kaplancıklı.
8. Design, synthesis and cytotoxicity of chimeric erlotinib-alkylphospholipid hybrids
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Md. Maqusood Alam, Ahmed H.E. Hassan, Kun Won Lee, Min Chang Cho, ... Yong Sup Lee.
9. Switching of Trp-214 intrinsic rotamer population in human serum albumin: An insight into the aftermath of embracing therapeutic bioorganic luminophore azapodophyllotoxin into sudlow site I
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Soham Mukherjee, Kapil Ganorkar, Ajay Kumar, Naina Sehra, Sujit Kumar Ghosh.
10. 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inflammatory and analgesic agents with an improved gastric profile: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study
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Asmaa Sakr, Hend Kothayer, Samy M. Ibrahim, Mohamed M. Baraka, Samar Rezq.
11. Repurposing approach identifies new treatment options for invasive fungal disease
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Isis Regina Grenier Capoci, Daniella Renata Faria, Karina Mayumi Sakita, Franciele Abigail Vilugron Rodrigues-Vendramini, ... Bernard Maigret.
12. Biological evaluation and structure activity relationship of 9-methyl-1-phenyl-9H-pyrido[3,4-b]indole derivatives as anti-leishmanial agents
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Penta Ashok, Subhash Chander, Terry K. Smith, Rajnish Prakash Singh, ... Murugesan Sankaranarayanan.
13. Heterocyclic cellular lipid peroxidation inhibitors inspired by the marine antioxidant barettin
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Christophe Labrière, Jeanette H. Andersen, Marte Albrigtsen, Jørn H. Hansen, Johan Svenson.
14. Encapsulation of ciprofloxacin within modified xanthan gum- chitosan based hydrogel for drug delivery
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Demiana H. Hanna, Gamal R. Saad.
15. The first target specific, highly diastereoselective synthesis, design and characterization of pyranoquinolinyl acrylic acid diastereomers as potential α-glucosidase inhibitors
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G. Lavanya, K. Venkatapathy, C.J. Magesh, M. Ramanathan, R. Jayasudha.
16. Novel salicylamide derivatives as potent multifunctional agents for the treatment of Alzheimer's disease: Design, synthesis and biological evaluation
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Qing Song, Yan Li, Zhongcheng Cao, Xiaoming Qiang, ... Yong Deng.
17. 1,3,4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities
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Marwa Ali A. Fathi, Amer Ali Abd El-Hafeez, Dalia Abdelhamid, Samar H. Abbas, ... Mohamed Abdel-Aziz.
18. 1-(2-Hydroxy-5-((trimethylsilyl)ethynyl)phenyl)ethanone based α,β-unsaturated derivatives an alternate to non-sulfonamide carbonic anhydrase II inhibitors, synthesis via Sonogashira coupling, binding analysis, Lipinsk’s rule validation
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Jamaluddin Mahar, Aamer Saeed, Kevin D. Belfield, Fayaz Ali Larik, ... Sung-Yum Seo.
19. Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface
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Giulia Elisa Guimarães Gonçalves, Thiago Rahal Morais, Kaio de Souza Gomes, Thais Alves Costa-Silva, ... Luciano Caseli.
20. Ebsulfur as a potent scaffold for inhibition and labelling of New Delhi metallo-β-lactamase-1 in vitro and in vivo
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Jianpeng Su, Jiayun Liu, Cheng Chen, Yuejuan Zhang, Kewu Yang.
21. Synthesis, molecular modeling and BACE-1 inhibitory study of tetrahydrobenzo[b] pyran derivatives
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Vijaya Bhaskar, Reshma Chowdary, Sheshagiri R. Dixit, Shrinivas D. Joshi.
22. Evaluation of blood-brain barrier penetration and examination of binding to human serum albumin of 7-O-arylpiperazinylcoumarins as potential antipsychotic agents
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Teresa Żołek, Orsolya Dömötör, Kinga Ostrowska, Éva A. Enyedy, Dorota Maciejewska.
23. Synthesis and biological evaluation of 7-(aminoalkyl)pyrazolo[1,5-a]pyrimidine derivatives as cathepsin K inhibitors
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Nejc Petek, Bogdan Štefane, Marko Novinec, Jurij Svete.
24. Discovery of a novel cathepsin inhibitor with dual autophagy-inducing and metastasis-inhibiting effects on breast cancer cells
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Lei Yuan, Jun Liu, Wenhui He, Youmei Bao, ... Enlong Ma.
25. TDP-43 specific reduction induced by Di-hydrophobic tags conjugated peptides
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Na Gao, Yun-Peng Huang, Ting-Ting Chu, Qian-Qian Li, ... Yan-Mei Li.
26. Synthesis and anti-inflammatory activity of sulfonamides and carboxylates incorporating trimellitimides: Dual cyclooxygenase/carbonic anhydrase inhibitory actions
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Alaa A.-M. Abdel-Aziz, Andrea Angeli, Adel S. El-Azab, Mohammed E.A. Hammouda, ... Claudiu T. Supuran.
27. Phenylpropanoids and lignans from Prunus tomentosa seeds as efficient β-amyloid (Aβ) aggregation inhibitors
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Qingbo Liu, Jie Wang, Bin Lin, Zhuo-Yang Cheng, ... Shao-Jiang Song.
28. 3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation
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Giuseppe Floresta, Agostino Cilibrizzi, Vincenzo Abbate, Ambra Spampinato, ... Antonio Rescifina.
29. Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/β-catenin signalling pathway agonists
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Duo-zhi Chen, Bi-juan Yang, Xiao-li He, Shi-rui Fan, ... Xiao-jiang Hao.
30. Artemisianins A-D, new stereoisomers of seco-guaianolide involved heterodimeric [4+2] adducts from Artemisia argyi induce apoptosis via enhancement of endoplasmic reticulum stress
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Gui-Min Xue, Dong-Rong Zhu, Chao Han, Xiao-Bing Wang, ... Ling-Yi Kong.
31. Synthesis, molecular docking and cholinesterase inhibitory activity of hydroxylated 2-phenylbenzofuran derivatives
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Antonella Fais, Amit Kumar, Rosaria Medda, Francesca Pintus, ... Giovanna L. Delogu.
32. New tirucallane triterpenoids from Picrasma quassioides with their potential antiproliferative activities on hepatoma cells
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Wen-Yu Zhao, Jing-Jie Chen, Chun-Xin Zou, Ying-Ying Zhang, ... Shao-Jiang Song.
33. Synthesis and computer-aided analysis of the role of linker for novel ligands of the 5-HT6 serotonin receptor among substituted 1,3,5-triazinylpiperazines
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Dorota Łażewska, Rafał Kurczab, Małgorzata Więcek, Grzegorz Satała, ... Jadwiga Handzlik.
34. Synthesis of 8-hydroxyquinoline glycoconjugates and preliminary assay of their β1,4-GalT inhibitory and anti-cancer properties
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Monika Krawczyk, Gabriela Pastuch-Gawolek, Anna Mrozek-Wilczkiewicz, Michal Kuczak, ... Robert Musiol.
35. The synthesis and anticancer activities of chiral epoxy-substituted chromone analogs
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Hyunji Jo, Seung Hee Seo, Younghwa Na, Youngjoo Kwon.
36. Combined molecular modeling and cholinesterase inhibition studies on some natural and semisynthetic O-alkylcoumarin derivatives
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Ilkay Erdogan Orhan, F. Sezer Senol Deniz, Ramin Ekhteiari Salmas, Serdar Durdagi, ... Serena Fiorito.
37. Multi-target inhibitors against Alzheimer disease derived from 3-hydrazinyl 1,2,4-triazine scaffold containing pendant phenoxy methyl-1,2,3-triazole: Design, synthesis and biological evaluation
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Mahnaz Yazdani, Najmeh Edraki, Rashid Badri, Mehdi Khoshneviszadeh, ... Omidreza Firuzi.
38. Xanthenone-based hydrazones as potent α-glucosidase inhibitors: Synthesis, solid state self-assembly and in silico studies
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Qamar-un-Nisa Tariq, Sana Malik, Ajmal Khan, Muhammad Moazzam Naseer, ... Zahid Shafiq.
39. Hydrolases-mediated transformation of oleuropein into demethyloleuropein
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Luca Cariati, Manuela Oliverio, Francesco G. Mutti, Sonia Bonacci, ... Antonio Procopio.
40. Design, synthesis and biological evaluation of novel indole derivatives as potential HDAC/BRD4 dual inhibitors and anti-leukemia agents
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Gaoliang Cheng, Zhi Wang, Jinyu Yang, Yu Bao, ... Dan Liu.
41. N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines
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Jian Zhou, Arvind Negi, Styliana I. Mirallai, Rolf Warta, ... Paul V. Murphy.
42. Design and analysis of EphA2-SAM peptide ligands: A multi-disciplinary screening approach
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Flavia Anna Mercurio, Concetta Di Natale, Luciano Pirone, Daniela Marasco, ... Marilisa Leone.
43. Antiproliferative 3-deoxysphingomyelin analogs: Design, synthesis, biological evaluation and molecular docking of pyrrolidine-based 3-deoxysphingomyelin analogs as anticancer agents
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Ahmed H.E. Hassan, Hye Rim Park, Yoon Mi Yoon, Hye In Kim, ... Yong Sup Lee.
44. Design, synthesis, DNA assessment and molecular docking study of novel 2-(pyridin-2-ylimino)thiazolidin-4-one derivatives as potent antifungal agents
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Nadia Hanafy Metwally, Ibrahim Taha Radwan, Walaa Salah El-Serwy, Mohamed Ahmed Mohamed.
45. Design, synthesis and biological evaluation of novel β-pinene-based thiazole derivatives as potential anticancer agents via mitochondrial-mediated apoptosis pathway
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Yunyun Wang, Chenliang Wu, Qiangjian Zhang, Yu Shan, ... Shifa Wang.
46. Synthesis, ADME, docking studies and in vivo anti-hyperglycaemic potential estimation of novel Schiff base derivatives from octadec-9-enoic acid
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Garima Kapoor, Dharam Pal Pathak, Rubina Bhutani, Asif Husain, ... Md. Azhar Iqbal.
47. Structure-activity relationship of pyrazolo pyrimidine derivatives as inhibitors of mitotic kinesin Eg5 and anticancer agents
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P. Muthuraja, V. Veeramani, S. Prakash, M. Himesh, ... P. Manisankar.
48. Bioactive butylphthalide derivatives from Ligusticum chuanxiong
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Xu Zhang, Zi-ming Feng, Ya-nan Yang, Jian-shuang Jiang, Pei-cheng Zhang.
49. Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity
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Dilan Ozmen Ozgun, Halise Inci Gul, Cem Yamali, Hiroshi Sakagami, ... Claudiu T. Supuran.
50. One-pot four-component synthesis of thiazolidin-2-imines using CuI/ZnII dual catalysis: A new class of acetylcholinesterase inhibitors
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Syeda Aaliya Shehzadi, Imtiaz Khan, Aamer Saeed, Fayaz Ali Larik, ... Sung-Yum Seo.
51. Antibody recognition by a novel microgel photonic crystal
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Na Sai, Zhong Sun, Yuntang Wu, Guowei Huang.
52. Identification of osimertinib (AZD9291) as a lysine specific demethylase 1 inhibitor
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Zhong-Rui Li, Feng-Zhi Suo, Bo Hu, Yan-Jia Guo, ... Hong-Min Liu.
53. Nitric oxide inhibitory limonoids as potential anti-neuroinflammatory agents from Swietenia mahagoni
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Zhaoyu Shi, Lijun An, Xueyuan Yang, Yaru Xi, ... Yuanqiang Guo.
54. Synthesis and identification of novel pyridazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregation
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Syed Usama Bin Farrukh, Ibrahim Javed, Abdul Qayyum Ather, Abdul-Hamid Emwas, ... Rahman Shah Zaib Saleem.
55. Synthesis of a new disulfide Fmoc monomer for creating biologically susceptible linkages in peptide nucleic acid oligomers
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Brandon Campbell, Taylor Hood, Nathaniel Shank.
56. A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies
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Khaled O. Mohamed, Islam Zaki, Ibrahim M. El-Deen, Mohammed K. Abdelhameid.
