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Current Opinion in Toxicology
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1. Systems biology approaches to interpreting genomic data
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Twan van den Beucken.
1. Organs-on-Chips: a new paradigm for safety assessment of drug-induced thrombosis
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Patrick Ng, Chaitra Belgur, Sonalee Barthakur, Andries D. van der Meer, ... Riccardo Barrile.
1. Supporting systems science through in silico applications: A focus on informing metabolic mechanisms Jeremy
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A. Leonard.
1. A pragmatic approach for human risk assessment of chemical mixtures
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Julie Boberg, Marianne Dybdahl, Annette Petersen, Ulla Hass, ... Anne Marie Vinggaard.
1. Mechanisms of chromium-induced toxicity
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Thomas Liborio DesMarias, Max Costa.
1. Editorial Board
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2. Omics-based input and output in the development and use of adverse outcome pathways
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Mathieu Vinken.
2. Off-target drug effects on platelet function: Protecting an Achilles heel of drug development
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James D. McFadyen, Himawan Fernando, Karlheinz Peter.
2. Human in vitro models of nonalcoholic fatty liver disease
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Fabrice A. Müller, Shana J. Sturla.
2. Chemical risk assessment based on in vitro and human biomonitoring data: A case study on thyroid toxicants
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Hanna K.L. Johansson, Julie Boberg, Marianne Dybdahl, Marta Axelstad, Anne Marie Vinggaard.
2. Inorganic arsenic: a nongenotoxic threshold carcinogen
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Samuel M. Cohen, Lora L. Arnold, Joyce S. Tsuji.
2. Editorial overview on Oxidative Toxicology: From molecules to cells to tissues
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Dimitrios Kouretas, Aristidis S. Veskoukis, James R. Roede, Aristidis M. Tsatsakis.
3. Use of genome editing tools in environmental health research
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Julia E. Rager, Celeste Carberry, Rebecca C. Fry.
3. Microphysiological systems in the evaluation of hematotoxicities during drug development
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Eva-Maria Dehne, Annika Winter, Uwe Marx.
3. Public data sources to support systems toxicology applications
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Allan Peter Davis, Jolene Wiegers, Thomas C. Wiegers, Carolyn J. Mattingly.
3. Regulatory use and acceptance of alternative methods for chemical hazard identification
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Patience Browne, Nathalie Delrue, Anne Gourmelon.
3. Impact of electronic cigarette aerosols on pregnancy and early development
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Marcus Orzabal, Jayanth Ramadoss.
3. Influence of genetic polymorphism on pesticide-induced oxidative stress
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Chiara Costa, Edoardo Miozzi, Michele Teodoro, Concettina Fenga.
4. Next-generation sequencing data for use in risk assessment
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Bruce Alexander Merrick.
4. Drug-induced thrombocytopenia: mechanisms and relevance in preclinical safety assessment
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Padma Kumar Narayanan, Scott Henry, Nianyu Li.
4. Networks at the nexus of systems biology and the exposome
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Vrinda Kalia, Dean P. Jones, Gary W. Miller.
4. The virtual human in chemical safety assessment
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Aldert H. Piersma, Jan van Benthem, Janine Ezendam, Yvonne CM. Staal, Anne S. Kienhuis.
4. Polychlorinated biphenyls and nonalcoholic fatty liver disease
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Banrida Wahlang, Josiah E. Hardesty, Jian Jin, K. Cameron Falkner, Matthew C. Cave.
4. Oxidative stress and its biomarkers in microalgal ecotoxicology
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K.S. Pikula, A.M. Zakharenko, V. Aruoja, K.S. Golokhvast, A.M. Tsatsakis.
5. Genomic tools for environmental epigenetics and implications for public health
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Bambarendage P.U. Perera, Laurie K. Svoboda, Dana C. Dolinoy.
5. Methods for measurement of platelet function in the assessment of nonclinical drug safety and implications for translatability
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David Ledieu, Serge Côté.
5. Confidence in metabolite identification dictates the applicability of metabolomics to regulatory toxicology
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Julia M. Malinowska, Mark R. Viant.
5. Paradigm shift in safety assessment using new approach methods: The EU-ToxRisk strategy
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R. Graepel, B. Ter Braak, S.E. Escher, C. Fisher, ... B. van de Water.
5. Toxicant and teratogenic effects of prenatal alcohol
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Amanda H. Mahnke, Amy M. Adams, Andrew Z Wang, Rajesh C. Miranda.
5. Biogenic aldehyde-mediated mechanisms of toxicity in neurodegenerative disease
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Brianna S. Cagle, Rachel A. Crawford, Jonathan A. Doorn.
6. Toxicogenomic applications in risk assessment at Health Canada
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Carole L. Yauk, Carmen Cheung, Tara S. Barton-Maclaren, Sherri Boucher, ... Cindy L.A. Woodland.
6. Systems toxicology meta-analysis—From aerosol exposure to nanotoxicology
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Marja Talikka, Vincenzo Belcastro, Sylvain Gubian, Florian Martin, ... Julia Hoeng.
6. Estimating uncertainty in the context of new approach methodologies for potential use in chemical safety evaluation
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Ly Ly Pham, Thomas Y. Sheffield, Prachi Pradeep, Jason Brown, ... Katie Paul Friedman.
6. Mechanism-based novel antidotes for organophosphate neurotoxicity
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Doodipala Samba Reddy.
6. Toxicant-mediated redox control of proteostasis in neurodegeneration
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Stefanos Aivazidis, Colin C. Anderson, James R. Roede.
7. CRISPR genomic screening informs gene–environment interactions
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Amin Sobh, Chris Vulpe.
7. Embracing systems toxicology at single-cell resolution
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Qiang Zhang, W. Michael Caudle, Jingbo Pi, Sudin Bhattacharya, ... Rory B. Conolly.
7. The use of systems biology in chemical risk assessment
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Alejandro Aguayo-Orozco, Olivier Taboureau, Søren Brunak.
7. Context is King — Questioning the causal role of DNA methylation in environmentally induced changes in gene expression
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Yudhishtar Bedi, Michael C. Golding.
7. Is Nrf2-ARE a potential target in NAFLD mitigation?
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Lu Li, Jingqi Fu, Jing Sun, Dan Liu, ... Jingbo Pi.
8. Integrating gene expression biomarker predictions into networks of adverse outcome pathways
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J. Christopher Corton.
8. A proposal for creating a taxonomy of chemical interactions using concepts from the aggregate exposure and adverse outcome pathways
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Paul Price, Jeremy Leonard.
8. Systems modeling of developmental vascular toxicity
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Katerine S. Saili, Jill A. Franzosa, Nancy C. Baker, Robert G. Ellis-Hutchings, ... Thomas B. Knudsen.
8. Mechanistic considerations for reduced endometrial cancer risk by smoking
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Martin van den Berg, Majorie B.M. van Duursen.
8. Sport nutrition, redox homeostasis and toxicity in sport performance
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Christina Yfanti, Chariklia K. Deli, Kalliopi Georgakouli, Ioannis Fatouros, Athanasios Z. Jamurtas.
9. Ontology-based data integration for advancing toxicological knowledge
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R.R. Boyles, A.E. Thessen, A. Waldrop, M.A. Haendel.
9. Considerations for strategic use of high-throughput transcriptomics chemical screening data in regulatory decisions
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Joshua Harrill, Imran Shah, R. Woodrow Setzer, Derik Haggard, ... Russell S. Thomas.
9. Oxidative toxicology of bleomycin: Role of the extracellular redox environment
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Ayed Allawzi, Hanan Elajaili, Elizabeth F. Redente, Eva Nozik-Grayck.
10. An assessment of environmental health measures in the Deepwater Horizon Research Consortia
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Huaqin Pan, Stephen W. Edwards, Cataia Ives, Hannah Covert, ... Carol M. Hamilton.
10. New approach methodologies for exposure science
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10. Engineered nanomaterials and oxidative stress: Current understanding and future challenges
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Ryan P. Mendoza, Jared M. Brown.
11. Mechanistic integration of exposure and effects: advances to apply systems toxicology in support of regulatory decision-making
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Annie M. Jarabek, David E. Hines.
11. Transforming regulatory safety evaluations using New Approach Methodologies: A perspective of an industrial toxicologist
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Richard A. Becker.
11. Oxidative stress induced by electronic nicotine delivery systems (ENDS): Focus on respiratory system
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Gozde Isik Andrikopoulos, Zoi Zagoriti, Stavros Topouzis, Konstantinos Poulas.
12. Predictive in vitro toxicology screening to guide chemical design in drug discovery
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Julia Johansson, Marie H. Larsson, Jorrit J. Hornberg.
12. Redox metabolism of ingested arsenic: Integrated activities of microbiome and host on toxicological outcomes
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Barbara A. Roggenbeck, Elaine M. Leslie, Seth T. Walk, Edward E. Schmidt.
13. A battery of translational biomarkers for the assessment of the in vitro and in vivo antioxidant action of plant polyphenolic compounds: The biomarker issue
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Aristidis Veskoukis, Efthalia Kerasioti, Alexandros Priftis, Paraskevi Kouka, ... Dimitrios Kouretas.
14. Lipid peroxidation derived reactive aldehydes in alcoholic liver disease
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Tác giả
Hadi Ali, Mohammed A. Assiri, Colin T. Shearn, Kristofer S. Fritz.
