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Volume 21, Issue 3, May 2019
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1. Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species
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Tác giả
Chuenlei Parng, Michael Bolt, Debra D. Pittman, Teresa Caiazzo.
2. Dissolution Chamber for Small Drug Delivery System in the Periodontal Pocket
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Tác giả
Wei Ren, Michael Murawsky, Terri La Count, Apipa Wanasathop, Xin Hao.
3. CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies
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Tác giả
Jonathan P. Mochel, Stephen C. Ekker, Chad M. Johannes.
4. Bacteriophage PEV20 and Ciprofloxacin Combination Treatment Enhances Removal of Pseudomonas aeruginosa Biofilm Isolated from Cystic Fibrosis and Wound Patients
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Tác giả
Rachel Yoon Kyung Chang, Theerthankar Das, Jim Manos, Elizabeth Kutter.
5. HER3-Targeted Affibodies with Optimized Formats Reduce Ovarian Cancer Progression in a Mouse Xenograft Model
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Tác giả
John S. Schardt, Madeleine Noonan-Shueh, Jinan M. Oubaid.
6. Trial Design and Statistical Considerations on the Assessment of Pharmacodynamic Similarity
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Tác giả
Peijuan Zhu, Chyi-Hung Hsu, Jason Liao, Steven Xu, Liping Zhang.
7. Neutralizing Antibody Assay Development with High Drug and Target Tolerance to Support Clinical Development of an Anti-TFPI Therapeutic Monoclonal Antibody
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Tác giả
Yuhong Xiang, Chuenlei Parng, Katrina Olson, Elena Seletskaia.
8. Mechanisms of CYP3A Induction During Pregnancy: Studies in HepaRG Cells
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Tác giả
Madhav Sachar, Edward J. Kelly, Jashvant D. Unadkat.
9. Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective
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Tác giả
Jinjiang Li, Mary E. Krause, Xiaodong Chen, Yuan Cheng, Weiguo Dai.
10. Theoretical Considerations for Direct Translation of Unbound Liver-to-Plasma Partition Coefficient from In Vitro to In Vivo
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Tác giả
Zhenhong Li, Li Di, Tristan S. Maurer.
11. Simulating the Impact of Elevated Levels of Interleukin-6 on the Pharmacokinetics of Various CYP450 Substrates in Patients with Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorders in Different Ethnic Populations
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Tác giả
Krishna K. Machavaram, Chihiro Endo-Tsukude, Kimio Terao.
12. Effect of Dibasic Calcium Phosphate Incorporation on Cellulose Nanocrystal/Chitosan Hydrogel Properties for the Treatment of Vertebral Compression Fractures
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Tác giả
Soheila Ali Akbari Ghavimi, Ethan S. Lungren, Jessica L. Stromsdorfer.
13. A Receiver Operating Characteristic Framework for Non-adherence Detection Using Drug Concentration Thresholds—Application to Simulated Risperidone Data in Schizophrenic Patients
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Tác giả
Carlos Pérez-Ruixo, Bart Remmerie, Juan José Peréz-Ruixo, An Vermeulen.
14. Pharmacokinetic Properties of Humanized IgG1 and IgG4 Antibodies in Preclinical Species: Translational Evaluation
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Tác giả
Mohammad Tabrizi, Divas Neupane, Sophia E. Elie, Harish Shankaran.
15. Scaling Drug Clearance from Adults to the Young Children for Drugs Undergoing Hepatic Metabolism: A Simulation Study to Search for the Simplest Scaling Method
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Tác giả
E. A. M. Calvier, E. H. J. Krekels, T. N. Johnson, A. Rostami-Hodjegan.
16. Variability Attribution for Automated Model Building
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Tác giả
Moustafa M. A. Ibrahim, Rikard Nordgren, Maria C. Kjellsson.
17. Dissolution Edge Charts for Immediate Release Products and Their Applications: a Simulation Study to Aid the Setting of Specifications
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Tác giả
John Z. Duan.
18. A Reappraisal of Sedimentation Nonideality Coefficients for the Analysis of Weak Interactions of Therapeutic Proteins
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Tác giả
Sumit K. Chaturvedi, Peter Schuck.
19. Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment
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Tác giả
Moustafa M. A. Ibrahim, Sebastian Ueckert, Svetlana Freiberga.
20. A Density-Changing Centrifugation Method for Efficient Separation of Free Drugs from Drug-Loaded Particulate Delivery Systems
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Tác giả
Lu Han, Hongyan Zhan, Xun Sun, Zhi-Rong Zhang, Li Deng.
21. First-Principles and Empirical Approaches to Predicting In Vitro Dissolution for Pharmaceutical Formulation and Process Development and for Product Release Testing
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Tác giả
Nikolay Zaborenko, Zhenqi Shi, Claudia C. Corredor.
