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Cancer Chemotherapy and Pharmacology
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1. Alternative dosing regimens for atezolizumab: right dose, wrong frequency
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Tác giả
Daniel A. Goldstein, Mark J. Ratain.
1. The thioredoxin system and cancer therapy: a review
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Tác giả
Fariba Mohammadi, Arash Soltani.
1. Nanoparticle albumin-bound paclitaxel: a big nano for the treatment of gastric cancer
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Tác giả
G. Roviello, F. U. Conter, E. Mini, D. Generali.
1. The role of thioredoxin system in cancer: strategy for cancer therapy
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Tác giả
Jin-Jing Jia, Wen-Shuo Geng, Zhan-Qi Wang, Lei Chen.
1. Cancer immunotherapy: the art of targeting the tumor immune microenvironment
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Tác giả
Jesse Lopes da Silva.
1. Chemotherapy and cognition: comprehensive review on doxorubicin-induced chemobrain
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Tác giả
Sara Emad El-Agamy, Amal Kamal Abdel-Aziz.
1. Clinically relevant concentrations of lidocaine inhibit tumor angiogenesis through suppressing VEGF/VEGFR2 signaling
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Tác giả
Jin Gao, Huimin Hu, Xuesong Wang.
1. Regorafenib regressed a doxorubicin-resistant Ewing’s sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model
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Tác giả
Kentaro Miyake, Tasuku Kiyuna, Kei Kawaguchi.
1. SPP1 inhibition improves the cisplatin chemo-sensitivity of cervical cancer cell lines
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Tác giả
Xing Chen, Dongsheng Xiong, Liya Ye, Huichun Yang.
1. Prophylactic effect of scopolamine butylbromide, a competitive antagonist of muscarinic acetylcholine receptor, on irinotecan-related cholinergic syndrome
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Tác giả
Hirotoshi Iihara, Hironori Fujii, Chiaki Yoshimi.
1. Toll-like receptor/interleukin-1 domain innate immune signalling pathway genetic variants are candidate predictors for severe gastrointestinal toxicity risk following 5-fluorouracil-based chemotherapy
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Tác giả
Samantha K. Korver, Rachel J. Gibson.
1. Awakening the “guardian of genome”: reactivation of mutant p53
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Tác giả
Akshay Binayke, Sarthak Mishra, Prabhat Suman.
2. Dihydropyrimidine dehydrogenase in the metabolism of the anticancer drugs
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Tác giả
Vinay Sharma, Sonu Kumar Gupta, Malkhey Verma.
2. Prodrugs as drug delivery system in oncology
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Tác giả
J. Delahousse, C. Skarbek, A. Paci.
2. Resistance mechanisms and potent-targeted therapies of ROS1-positive lung cancer
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Tác giả
Annie Roys, Xing Chang, Yang Liu, Xiaobo Xu.
2. Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review
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Tác giả
Marie Lindhard Madsen, Hanne Due, Niels Ejskjær.
2. The role of apoptosis defects in malignant mesothelioma pathogenesis with an impact on prognosis and treatment
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Tác giả
Vasiliki Galani, Anna Varouktsi.
2. Uveal melanoma: physiopathology and new in situ-specific therapies
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Tác giả
E. B. Souto, A. Zielinska, M. Luis, C. Carbone.
2. d,l-Methadone does not improve radio- and chemotherapy in glioblastoma in vitro
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Tác giả
Henry Oppermann, Martina Matusova, Annegret Glasow.
2. Re-challenge of afatinib after 1st generation EGFR-TKI failure in patients with previously treated non-small cell lung cancer harboring EGFR mutation
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Tác giả
Ou Yamaguchi, Kyoichi Kaira, Atsuto Mouri.
2. Blockade of integrin β3 signals to reverse the stem-like phenotype and drug resistance in melanoma
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Tác giả
Xiaoxia Zhu, Xiaohua Tao, Wei Lu, Yang Ding.
2. Self-targeted knockdown of CD44 improves cisplatin sensitivity of chemoresistant non-small cell lung cancer cells
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Tác giả
Yu Hua Quan, Ji-Young Lim, Byeong Hyeon Choi.
2. 6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability
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Tác giả
Shengnan Du, Jeffrey G. Sarver.
2. Autophagy and its potent modulators from phytochemicals in cancer treatment
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Tác giả
Chao-Yue Sun, Qian-Yu Zhang, Guang-Juan Zheng.
3. A reliable method to determine which candidate chemotherapeutic drugs effectively inhibit tumor growth in patient-derived xenografts (PDX) in single mouse trials
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Tác giả
Derek Gordon, David E. Axelrod.
3. Polymorphisms of genes encoding drug transporters or cytochrome P450 enzymes and association with clinical response in cancer patients: a systematic review
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Tác giả
Inthuorn Kulma, Kanyarat Boonprasert.
3. Current status of nanomedicine in the chemotherapy of breast cancer
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Tác giả
A. I. Fraguas-Sánchez, C. Martín-Sabroso.
3. Cytochrome P450 3A4, 3A5, and 2C8 expression in breast, prostate, lung, endometrial, and ovarian tumors: relevance for resistance to taxanes
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Tác giả
Maarten van Eijk, René J. Boosman.
3. Moxetumomab pasudotox-tdfk for relapsed/refractory hairy cell leukemia: a review of clinical considerations
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Tác giả
Carmen F. Nobre, Matthew J. Newman, Anne DeLisa.
3. Platinum-free interval affects efficacy of following treatment for platinum-refractory or -resistant ovarian cancer
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Tác giả
Mayumi Kobayashi-Kato, Mayu Yunokawa, Seiko Bun.
3. A phase I study of gemcitabine + dasatinib (gd) or gemcitabine + dasatinib + cetuximab (GDC) in refractory solid tumors
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Tác giả
Niharika B. Mettu, Donna Niedzwiecki.
3. Potential drug–drug interactions and nephrotoxicity in hematopoietic stem cell transplant adult recipients during bone marrow transplantation unit stay
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Tác giả
Lydia Sanchez, Astrid Bacle, Thierry Lamy.
3. Upregulation of MTA1 expression by human papillomavirus infection promotes CDDP resistance in cervical cancer cells via modulation of NF-κB/APOBEC3B cascade
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Tác giả
Qiu-ping Jia, Chang-you Yan, Xue-rong Zheng.
3. A phase II trial of the effect of perindopril on hand–foot skin reaction (HFSR) incidence and severity in patients receiving regorafenib for refractory mCRC
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Tác giả
Barbara L. Melosky, Howard John Lim.
3. Role of the HDAC6/STAT3 pathway in regulating PD-L1 expression in osteosarcoma cell lines
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Tác giả
Ajimu Keremu, Abudusaimi Aimaiti, Zhilin Liang.
3. Population pharmacokinetics of FOLFIRINOX: a review of studies and parameters
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Tác giả
Laure Deyme, Dominique Barbolosi.
4. A prospective phase I multicentre randomized cross-over pharmacokinetic study to determine the effect of food on abiraterone pharmacokinetics
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Tác giả
Floor J. E. Lubberman, Guillemette E. Benoist.
4. Exposure–response analysis to inform the optimal dose of veliparib in combination with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer patients
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Tác giả
Silpa Nuthalapati, Sven Stodtmann.
4. Population pharmacokinetics of trabectedin in adolescent patients with cancer
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Tác giả
Italo Poggesi, Belén Valenzuela, Daniele Ouellet.
4. Application of time-dependent modeling for the exposure–efficacy analysis of ceritinib in untreated ALK-rearranged advanced NSCLC patients
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Tác giả
Yvonne Y. Lau, Wen Gu, Yu-Yun Ho, Ying Hong.
4. Priming with GM-CSF instead of G-CSF enhances CAG-induced apoptosis of acute monocytic leukemia cells in vitro
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Tác giả
Meiqing Lei, Limin Liu, Depei Wu.
4. Sunitinib in pediatric patients with advanced gastrointestinal stromal tumor: results from a phase I/II trial
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Tác giả
Arnauld C. Verschuur, Viera Bajčiová.
4. Placental growth factor is a predictive biomarker for ramucirumab treatment in advanced gastric cancer
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Tác giả
Makoto Natsume, Takaya Shimura, Hiroyasu Iwasaki.
4. Pharmacokinetics, absorption, metabolism, and excretion of [14C]ivosidenib (AG-120) in healthy male subjects
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Tác giả
Chandra Prakash, Bin Fan, Syed Altaf, Sam Agresta.
4. Analysis of SPARC and TUBB3 as predictors for prognosis in esophageal squamous cell carcinoma receiving nab-paclitaxel plus cisplatin neoadjuvant chemotherapy: a prospective study
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Tác giả
Lei Gong, Weimin Mao, Qixun Chen, Youhua Jiang.
4. Randomized phase II trial of the prophylactic use of celecoxib for the prevention of oxaliplatin-related peripheral vascular pain in Capeox (YCOG1205)
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Tác giả
Yusuke Suwa, Jun Watanabe, Mitsuyoshi Ota.
4. Pharmacokinetics of liposomal curcumin (Lipocurc™) infusion: effect of co-medication in cancer patients and comparison with healthy individuals
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Tác giả
Gordon T. Bolger, Albert Licollari, Amin Tan.
4. Clinical and in vitro studies of the correlation between MGMT and the effect of streptozocin in pancreatic NET
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Tác giả
Susumu Hijioka, Keiichiro Sakuma, Masahiro Aoki.
5. Enhancing intratumoral biodistribution and antitumor activity of nab-paclitaxel through combination with a vascular disrupting agent, combretastatin A-4-phosphate
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Tác giả
Meng Gao, Dongjian Zhang, Nan Yao, Qiaomei Jin.
5. Optimal dose of sunitinib for long-term treatment in Japanese patients with renal cell carcinoma
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Tác giả
Yuto Yamada, Yuta Ohno, Yu Kato, Ryo Kobayashi.
5. Celastrol enhances TRAIL-induced apoptosis in human glioblastoma via the death receptor pathway
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Tác giả
Zhe Cha, Jianzhang Cheng, Hui Xiang, Jingjing Qin.
5. Electrophysiologic evaluation of facial nerve functions after oxaliplatin treatment
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Tác giả
Oznur Yigit, Mavis Emel Kulak Kayikci.
5. Ineligibility for the PACIFIC trial in unresectable stage III non-small cell lung cancer patients
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Tác giả
Kazutaka Hosoya, Daichi Fujimoto, Hayato Kawachi.
5. Resistance models to EGFR inhibition and chemotherapy in non-small cell lung cancer via analysis of tumour size dynamics
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Tác giả
Hitesh B. Mistry, Gabriel Helmlinger.
5. Outcomes of preoperative S-1 and docetaxel combination chemotherapy in patients with locally advanced gastric cancer
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Tác giả
Takashi Kosaka, Hirotoshi Akiyama, Hiroshi Miyamoto.
5. Gefitinib exposure and occurrence of interstitial lung disease in Japanese patients with non-small-cell lung cancer
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Tác giả
Toshio Kawata, Mitsuo Higashimori, Yohji Itoh.
5. Encapsulation of a new quinoxaline derivative in PLGA alters the pattern of its anticancer potency and induces apoptosis
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Tác giả
Entsar A. Saad, Heba M. Waly.
5. Severe hypersensitivity reactions to platinum compounds post-pressurized intraperitoneal aerosol chemotherapy (PIPAC): first literature report
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Tác giả
Matthieu Siebert, Mohammad Alyami, Frederic Mercier.
5. Knockdown of long non-coding HOTAIR enhances the sensitivity to progesterone in endometrial cancer by epigenetic regulation of progesterone receptor isoform
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Tác giả
B Shuqi Chi, Yan Liu, Xing Zhou, Dilu Feng.
5. Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy
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Tác giả
Jacob Nersting, Stine Nygaard Nielsen.
6. Skin platinum deposition in colorectal cancer patients following oxaliplatin-based therapy
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Tác giả
Yanshuo Cao, Qing Chang, Wenjiang Zhang.
6. Population pharmacokinetics of siltuximab: impact of disease state
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Tác giả
Mina Nikanjam, Jin Yang, Edmund V. Capparelli.
6. Species-specific optimization of PEG~SN-38 prodrug pharmacokinetics and antitumor effects in a triple-negative BRCA1-deficient xenograft
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Tác giả
Shaun D. Fontaine, Byron Hann, Ralph Reid.
6. BRAF mutation status might contribute an effect on both disease-free and overall survival in stage III cutaneous melanomas treated with intermediate dose interferon-alpha
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Tác giả
Faruk Tas, Kayhan Erturk.
6. Neoadjuvant chemotherapy in patients with advanced endometrial cancer
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Tác giả
Olivia R. Khouri, Melissa K. Frey, Fernanda Musa.
6. Monomethyl auristatin E-conjugated anti-EGFR antibody inhibits the growth of human EGFR-positive non-small cell lung cancer
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Tác giả
Zhuanglin Li, Mingxue Wang, Deling Yu, Wenting Luo.
6. First-in-human study to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of the anti-CD27L antibody-drug conjugate AMG 172 in patients with relapsed/refractory renal cell carcinoma
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Tác giả
Christophe Massard, Jean-Charles Soria.
6. SCMCIE94: an intensified pilot treatment protocol known to be associated with cure in CD 56-negative non-pelvic isolated Ewing sarcoma (EWS) is also associated with no early relapses in non-metastatic extremity EWS
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Tác giả
Ian Joseph Cohen, Helen Toledano, Jerry Stein.
6. Molecular targeting of HER2-overexpressing biliary tract cancer cells with trastuzumab emtansine, an antibody–cytotoxic drug conjugate
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Tác giả
Yoriko Yamashita-Kashima, Yasushi Yoshimura.
6. Dose-dense paclitaxel/carboplatin as neo-adjuvant chemotherapy followed by radical surgery in locally advanced cervical cancer: a prospective phase II study
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Tác giả
Gabriella Ferrandina, Giacomo Corrado.
6. A phase I study of single-agent BEZ235 special delivery system sachet in Japanese patients with advanced solid tumors
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Tác giả
Masanori Toyoda, Koichiro Watanabe, Taro Amagasaki.
6. Mononuclear phagocyte system function and nanoparticle pharmacology in obese and normal weight ovarian and endometrial cancer patients
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Tác giả
Brittney R. Starling, Parag Kumar, Andrew T. Lucas.
7. Phase I trial of belinostat in combination with 13-cis-retinoic acid in advanced solid tumor malignancies: a California Cancer Consortium NCI/CTEP sponsored trial
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Tác giả
Thehang Luu, Paul Frankel, Jan H. Beumer, Dean Lim.
7. Population pharmacokinetics and exposure–overall survival analysis of the transforming growth factor-β inhibitor galunisertib in patients with pancreatic cancer
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Tác giả
Ivelina Gueorguieva, Josep Tabernero, Davide Melisi.
7. A simple ex vivo bioassay for 5-FU transport into healthy buccal mucosal cells
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Tác giả
Kathryn E. Burns, Daniel Allright, David Porter.
7. In vitro evaluation of FL118 and 9-Q20 cytotoxicity and cellular uptake in 2D and 3D different cell models
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Tác giả
Qi Weng, Leilei Zhou, Lihua Xia, Yixin Zheng.
7. SN-38, the active metabolite of irinotecan, inhibits the acute inflammatory response by targeting toll-like receptor 4
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Tác giả
Deysi Viviana Tenazoa Wong.
7. Pharmacokinetics and safety of lobaplatin plus etoposide in Chinese men older than 65 years with extensive-stage small cell lung cancer: a phase II clinical trial
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Tác giả
Jianhua Chen, Bingyang Liu, Fang Zhang, Weiping Cui.
7. LncRNA SNHG16 sponges miR-98-5p to regulate cellular processes in osteosarcoma
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Tác giả
Shian Liao, Shuxing Xing, Yanhui Ma.
7. A study of second-line irinotecan plus cisplatin vs. irinotecan alone in platinum-naïve patients with early relapse of gastric cancer refractory to adjuvant S-1 monotherapy: exploratory subgroup analysis of the randomized phase III TRICS trial
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Tác giả
Kazuhiro Nishikawa, Kenta Murotani.
7. Influence of oral magnesium-containing supplement and antacid administration on hypomagnesemia induced by panitumumab
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Tác giả
Junya Sato, Hiroshi Ishikawa, Rei Tanaka.
7. Low dosage of apatinib monotherapy as rescue treatment in advanced lung squamous cell carcinoma
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Tác giả
Da-xiong Zeng, Wei Lei, Chang-guo Wang.
7. Metastatic or locally advanced breast cancer patients: towards an expert consensus on nab-paclitaxel treatment in HER2-negative tumours—the MACBETH project
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Tác giả
Marina E. Cazzaniga, E. Ciruelos, A. Fabi.
7. Effects of CYP2D6*10 polymorphism on tamoxifen pharmacokinetics in patients with breast cancer in Asia: a meta-analysis
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Tác giả
Yu Bai, Hai-wei Wu, Yan-hua Zhang.
8. Upregulation of miR-519 enhances radiosensitivity of esophageal squamous cell carcinoma trough targeting PI3K/AKT/mTOR signaling pathway
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Tác giả
Yanshan Zhang, Weizuo Chen, Huijuan Wang.
8. Evaluation of the potential for QTc prolongation with avelumab
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Tác giả
Yulia Vugmeyster, Gülseren Güzel, Meliessa Hennessy.
8. Multiple administrations of fluconazole increase plasma exposure to ruxolitinib in healthy adult subjects
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Tác giả
Vassilios Aslanis, Kenichi Umehara, Felix Huth.
8. Pharmacokinetic and exposure–response analysis of pertuzumab in patients with HER2-positive metastatic gastric or gastroesophageal junction cancer
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Tác giả
Whitney P. Kirschbrown, Bei Wang, Ihsan Nijem.
8. Postoperative chemotherapy as adjuvant treatment for endometrioid adenocarcinoma: early stage vs late stage
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Tác giả
Mengmeng Lu, Jiaojiao Zheng, Nana Xu, Han Lin.
8. Population pharmacokinetics of PF-05280014 (a trastuzumab biosimilar) and reference trastuzumab (Herceptin®) in patients with HER2-positive metastatic breast cancer
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Tác giả
Xiaoying Chen, Cheryl Li, Reginald Ewesuedo.
8. The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model
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Tác giả
Takashi Higuchi, Kentaro Miyake, Norihiko Sugisawa.
8. Classification and regression tree-based prediction of 6-mercaptopurine-induced leucopenia grades in children with acute lymphoblastic leukemia
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Tác giả
Shaik Mohammad Naushad, Patchava Dorababu.
8. In vitro and in vivo anticancer effects of two quinoline–platinum(II) complexes on human osteosarcoma models
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Tác giả
Maria Carolina Ruiz, Agustina Resasco.
8. A retrospective study of the CHOP, CHOPE, and CHOPE/G regimens as the first-line treatment of peripheral T-cell lymphomas
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Tác giả
Xuyan Liu, Mingzi Yang, Meng Wu, Wen Zheng, Yan Xie.
8. Population pharmacokinetics and exposure–response assessment of veliparib co-administered with temozolomide in patients with myeloid leukemias
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Tác giả
Renu Singh, Shailly Mehrotra.
8. Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats
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Tác giả
Priyanka Arora, Courtney Huff Adams, Gary Gudelsky.
9. Endothelial nitric oxide synthase c.-813C>T predicts for proteinuria in metastatic breast cancer patients treated with bevacizumab-based chemotherapy
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Tác giả
Stefania Crucitta, Giuliana Restante, Marzia Del Re.
9. Phase I trial of pimasertib monotherapy in Japanese patients with solid tumors and those with hepatocellular carcinoma
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Tác giả
K. Yamazaki, T. Doi, M. Ikeda, T. Okusaka.
9. A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer
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Tác giả
Cody J. Peer, Keith T. Schmidt, Jessica D. Kindrick.
9. Identification of dinactin, a macrolide antibiotic, as a natural product-based small molecule targeting Wnt/β-catenin signaling pathway in cancer cells
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Tác giả
Aehtesham Hussain, Mohd Saleem Dar, Nasima Bano.
9. Second-line FOLFIRI plus ramucirumab with or without prior bevacizumab for patients with metastatic colorectal cancer
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Tác giả
Takeshi Suzuki, Eiji Shinozaki, Hiroki Osumi.
9. A single-center, open-label study investigating the excretion balance, pharmacokinetics, metabolism, and absolute bioavailability of a single oral dose of [14C]-labeled idasanutlin and an intravenous tracer dose of [13C]-labeled idasanutlin in a single co
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Tác giả
Zsuzsanna Pápai, Lin-Chi Chen, Daniel Da Costa.
9. Apatinib for chemotherapy-refractory extensive-stage SCLC: a retrospective study
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Tác giả
Hui Li, Jian Zeng, Xiangyu Jin, Xinmin Yu.
9. Safety assessment of anticancer drugs in association with radiotherapy in metastatic malignant melanoma: a real-life report
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Tác giả
Emmanuelle Couty, Alexis Vallard, Sandrine Sotton.
9. Pharmacokinetic and cytokine profiles of melanoma patients with dabrafenib and trametinib-induced pyrexia
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Tác giả
Hannah Yejin Kim, Janna K. Duong, Maria Gonzalez.
9. Targeted disruption of PI3K/Akt/mTOR signaling pathway, via PI3K inhibitors, promotes growth inhibitory effects in oral cancer cells
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Tác giả
Sadhna Aggarwal, Sarah John, Leena Sapra.
9. Population pharmacokinetic and covariate analyses of intravenous trastuzumab (Herceptin®), a HER2-targeted monoclonal antibody, in patients with a variety of solid tumors
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Tác giả
Angelica L. Quartino, Hanbin Li.
9. Effect of a high-fat meal on the relative bioavailability of H3B-6527, a novel FGFR4 inhibitor, in healthy volunteers
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Tác giả
Nathalie Rioux, Amy Kim, Darrell Nix, Todd Bowser.
10. ABCC11 gene polymorphism as a potential predictive biomarker for an oral 5-fluorouracil derivative drug S-1 treatment in non-small cell lung cancer
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Tác giả
Takehiro Uemura, Tetsuya Oguri, Ken Maeno.
10. Serum microRNA-21 predicted treatment outcome and survival in HER2-positive breast cancer patients receiving neoadjuvant chemotherapy combined with trastuzumab
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Tác giả
Baoquan Liu, Fei Su, Xiaohong Lv, Wenbo Zhang.
10. Identification of pharmacodynamic biomarkers and common molecular mechanisms of response to genotoxic agents in cancer cell lines
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Tác giả
Dong-Joon Min, Yingdong Zhao, Anne Monks.
10. Efficacy and safety of 4-weekly cabazitaxel for castration-resistant prostate cancer: a multi-institutional study
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Tác giả
Masaki Shiota, Motonobu Nakamura, Akira Yokomizo.
10. A panel of serum exosomal microRNAs as predictive markers for chemoresistance in advanced colorectal cancer
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Tác giả
Guoying Jin, Yuhang Liu, Jia Zhang, Zehua Bian.
10. Orally administered salecan ameliorates methotrexate-induced intestinal mucositis in mice
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Tác giả
Yan Gao, Qi Sun, Xiao Yang, Weiling Lu, Yang Zhao.
10. Comparison of palonosetron and granisetron in triplet antiemetic therapy in nonmetastatic breast cancer patients receiving high emetogenic chemotherapy: a multicenter, prospective, and observational study
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Tác giả
Murat Araz, Mustafa Karaagac, Levent Korkmaz.
10. Irinotecan induces enterocyte cell death and changes to muc2 and muc4 composition during mucositis in a tumour-bearing DA rat model
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Tác giả
Daniel Thorpe, Masooma Sultani, Andrea Stringer.
10. Population pharmacokinetics analysis of nivolumab in Asian and non-Asian patients with gastric and gastro-esophageal junction cancers
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Tác giả
Mayu Osawa, Mayumi Hasegawa, Akintunde Bello.
10. Evaluation of the effects of formulation, food, or a proton-pump inhibitor on the pharmacokinetics of glasdegib (PF-04449913) in healthy volunteers: a randomized phase I study
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Tác giả
Naveed Shaik, Brian Hee, Hua Wei, Robert R. LaBadie.
10. Prevalence of TPMT, ITPA and NUDT 15 genetic polymorphisms and their relation to 6MP toxicity in north Indian children with acute lymphoblastic leukemia
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Tác giả
Sanjeev Khera, Amita Trehan, Prateek Bhatia.
10. Phase I study of BNC105P, carboplatin and gemcitabine in partially platinum-sensitive ovarian cancer patients in first or second relapse (ANZGOG-1103)
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Tác giả
Kristina Lindemann, Philip J. Beale, Emma Rossi.
11. Dasatinib attenuates overexpression of Src signaling induced by the combination treatment of veliparib plus carboplatin in triple-negative breast cancer
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Tác giả
Yuliang Sun, Xiaoqian Lin, Jennifer Carlson Aske.
11. Real-world data on initial treatment strategies for older adult patients with endometrial cancer in Japan
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Tác giả
Mayu Yunokawa, Shinsuke Sasada, Yae Takehara.
11. Sunitinib rechallenge in advanced renal cell carcinoma: outcomes of a multicenter retrospective study
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Tác giả
Javier Munárriz, Gaspar Reynés.
11. A phase 1b, multicenter, open-label, dose-finding study of eribulin in combination with carboplatin in advanced solid tumors and non-small cell lung cancer
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Tác giả
Sanjay Goel, Umang Swami, Kirushna Kumar.
11. Safety, tolerability, and pharmacokinetics of anti-EGFRvIII antibody–drug conjugate AMG 595 in patients with recurrent malignant glioma expressing EGFRvIII
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Tác giả
Mark Rosenthal, Richard Curry, David A. Reardon.
11. Treatment with selenium-enriched Saccharomyces cerevisiae UFMG A-905 partially ameliorates mucositis induced by 5-fluorouracil in mice
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Tác giả
Bárbara A. A. Porto, Cinthia F. Monteiro.
11. De-escalated neoadjuvant therapy with nanoparticle albumin-bound paclitaxel and trastuzumab for low-risk pure HER2 breast cancer
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Tác giả
Satoru Tanaka, Nobuki Matsunami, Hirotaka Morishima.
11. Determination of melphalan in human plasma by UPLC–UV method
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Tác giả
Liusheng Huang, Vincent Cheah, Danna Chan.
11. Effect of niraparib on cardiac repolarization in patients with platinum-sensitive, recurrent epithelial ovarian, fallopian tube, and primary peritoneal cancer
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Tác giả
Kathleen Moore, John K. Chan.
11. A window-of-opportunity clinical trial of dasatinib in women with newly diagnosed endometrial cancer
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Tác giả
Linda R. Duska, Gina R. Petroni, Heather Lothamer.
11. A prospective study of a simple algorithm to individually dose high-dose methotrexate for children with leukemia at risk for methotrexate toxicities
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Tác giả
Jennifer H. Foster, Patrick A. Thompson.
11. Associations among regorafenib concentrations, severe adverse reactions, and ABCG2 and OATP1B1 polymorphisms
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Tác giả
Akimitsu Maeda, Kei Irie, Hitoshi Ando.
12. Alternative dosing regimens for atezolizumab: an example of model-informed drug development in the postmarketing setting
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Tác giả
Kari M. Morrissey, Mathilde Marchand, Hina Patel.
12. Dose escalation study of amrubicin and cisplatin with concurrent thoracic radiotherapy for limited-disease small cell lung cancer
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Tác giả
Midori Shimada, Hiroyuki Yamaguchi, Minoru Fukuda.
12. A phase I study of the PARP inhibitor niraparib in combination with bevacizumab in platinum-sensitive epithelial ovarian cancer: NSGO AVANOVA1/ENGOT-OV24
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Tác giả
Mansoor Raza Mirza, Troels K. Bergmann.
12. Spatial memory deficits in mice induced by chemotherapeutic agents are prevented by acetylcholinesterase inhibitors
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Tác giả
Rex M. Philpot, M. Ficken, B. E. Johns.
12. Phase I study of BGT226, a pan-PI3K and mTOR inhibitor, in Japanese patients with advanced solid cancers
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Tác giả
Hironobu Minami, Yutaka Fujiwara, Kei Muro.
12. Clinical characteristics, treatment patterns and outcomes of patients older than 80 years diagnosed with DLBCL in China over a 10-year period
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Tác giả
Zhan Shi, Xi Tang, Qianwen Shen, Jiayan Chen.
12. Equipotent doses of daunorubicin and idarubicin for AML: a meta-analysis of clinical trials versus in vitro estimation
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Tác giả
Sunil Adige, Rena G. Lapidus.
12. Disruption of CTLA-4 expression on peripheral blood CD8 + T cell enhances anti-tumor efficacy in bladder cancer
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Tác giả
Wei Zhang, Long Shi, Zhilong Zhao, Pingping Du.
12. Effect of aprepitant administration on CINV caused by cisplatin multi-day chemotherapy and pharmacokinetics of docetaxel
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Tác giả
Lin Guo, Hao Peng, Hua-Lin Cai, Dan Tang, Hao Hu.
12. Evaluation of the effects of an oral notch inhibitor, crenigacestat (LY3039478), on QT interval, and bioavailability studies conducted in healthy subjects
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Tác giả
Eunice Yuen, Maria Posada, Claire Smith.
12. Murine RAW264.7 cells as cellular drug delivery carriers for tumor therapy: a good idea?
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Tác giả
Huangliang Zheng, Jiaqi Li, Xiang Luo, Cong LI.
12. Regorafenib or rechallenge chemotherapy: which is more effective in the third-line treatment of metastatic colorectal cancer?
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Tác giả
Osman Köstek, Muhammet Bekir Hacıoğlu.
13. JOIN trial: treatment outcome and recovery status of peripheral sensory neuropathy during a 3-year follow-up in patients receiving modified FOLFOX6 as adjuvant treatment for stage II/III colon cancer
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Tác giả
Takayuki Yoshino, Masahito Kotaka.
13. A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients
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Tác giả
Tetsuo Tani, Katsuhiko Naoki, Hiroyuki Yasuda.
13. A drug–drug interaction study to assess the potential effect of acid-reducing agent, lansoprazole, on quizartinib pharmacokinetics
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Tác giả
Jianke Li, Denise Trone, Jeanne Mendell.
13. Genistein combined with FOLFOX or FOLFOX–Bevacizumab for the treatment of metastatic colorectal cancer: phase I/II pilot study
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Tác giả
Sofya Pintova, Sirish Dharmupari, Erin Moshier.
13. Oxaliplatin induces prostaglandin E2 release in vascular endothelial cells
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Tác giả
Satoru Matsunuma, Satoko Handa, Daisuke Kamei.
13. Inter- and intra-patient variability in pharmacokinetics of abiraterone acetate in metastatic prostate cancer
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Tác giả
Malmaruha Arasaratnam, Megan Crumbaker.
13. Investigation of anti-tumor effect of doxorubicin-loaded human serum albumin nanoparticles prepared by a desolvation technique
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Tác giả
Kotaro Kimura, Keishi Yamasaki, Koji Nishi.
13. The PVT1/miR-216b/Beclin-1 regulates cisplatin sensitivity of NSCLC cells via modulating autophagy and apoptosis
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Tác giả
Liangfeng Chen, Xiaobing Han, Zhongzhou Hu.
13. Changes in skeletal muscle area and lean body mass during pazopanib vs sunitinib therapy for metastatic renal cancer
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Tác giả
Osman Köstek, Erdem Yılmaz, Muhammet Bekir Hacıoğlu.
13. Clinical outcomes of oral metronomic vinorelbine in advanced non-small cell lung cancer: correlations with pharmacokinetics and MDR1 polymorphisms
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Tác giả
Milena Gusella, Felice Pasini, Donatella Caruso.
13. Octreotide SC depot in patients with acromegaly and functioning neuroendocrine tumors: a phase 2, multicenter study
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Tác giả
Marianne Pavel, Françoise Borson-Chazot.
13. Dose adjustment of irinotecan based on UGT1A1 polymorphisms in patients with colorectal cancer
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Tác giả
Hironori Fujii, Yunami Yamada, Daichi Watanabe.
14. BATF2 inhibits chemotherapy resistance by suppressing AP-1 in vincristine-resistant gastric cancer cells
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Tác giả
Wei Yang, Sihui Zhao, Bian Wu, Jianbiao Xu.
14. Development of a physiologically based pharmacokinetic model for intravenous lenalidomide in mice
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Tác giả
Jim H. Hughes, Richard N. Upton.
14. Preclinical efficacy of a novel dual PI3K/mTOR inhibitor, CMG002, alone and in combination with sorafenib in hepatocellular carcinoma
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Tác giả
Mi Na Kim, Seung Min Lee, Jin Sung Kim.
14. Incidence of and risk factors for cardiotoxicity after fluorouracil-based chemotherapy in locally advanced or metastatic gastric cancer patients
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Tác giả
Xuan Jin, Yu Bai, Lan Gao, Shikai Wu.
14. A single-arm phase II trial of weekly nanoparticle albumin-bound paclitaxel (nab-paclitaxel) monotherapy after standard of chemotherapy for previously treated advanced non-small cell lung cancer
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Tác giả
Yasuhiro Kato, Yusuke Okuma, Kageaki Watanabe.
14. Olanzapine-containing antiemetic therapy for the prevention of carboplatin-induced nausea and vomiting
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Tác giả
Kazuki Tanaka, Naoki Inui, Masato Karayama.
14. Docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy for patients with cervical esophageal cancer: a single-center retrospective study
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Tác giả
Makoto Sakai, Makoto Sohda, Hideyuki Saito.
14. The impact of genetic polymorphism on CYP19A1 in androgen-deprivation therapy among Japanese men
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Tác giả
Masaki Shiota, Naohiro Fujimoto.
14. A phase Ib dose allocation study of oral administration of lucitanib given in combination with fulvestrant in patients with estrogen receptor-positive and FGFR1-amplified or non-amplified metastatic breast cancer
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Tác giả
M. Campone, T. Bachelot, F. Penault-Llorca.
14. Safety and efficacy of trastuzumab administered as a 30-min infusion in patients with HER2-positive advanced gastric cancer
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Tác giả
Sung Yong Oh, Suee Lee, Seok Jae Huh, Jeeyun Lee.
14. Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion
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Tác giả
Abeer F. Alharbi, Robert A. Kratzke.
14. Pertuzumab, trastuzumab and taxane-based treatment for visceral organ metastatic, trastuzumab-naïve breast cancer: real-life practice outcomes
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Tác giả
Ece Esin, B. Oksuzoglu, A. Bilici, I. Cicin.
15. Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies
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Tác giả
Leonard J. Appleman, Jan H. Beumer, Yixing Jiang.
15. Italian survey on cetuximab-based therapy of elderly patients with metastatic colorectal cancer
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Tác giả
Gerardo Rosati, Raffaele Addeo, Giuseppe Aprile.
15. A two centers study of postoperative adjuvant chemotherapy with S-1 versus SOX/XELOX regimens for gastric cancer after D2 resection: a cohort study
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Tác giả
Song Zheng, Yao Zhou, Yangcheng Sun, Zhen Wang.
15. A high AR:ERα or PDEF:ERα ratio predicts a sub-optimal response to tamoxifen therapy in ERα-positive breast cancer
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Tác giả
Lu Cao, Guomin Xiang, Fang Liu, Cong Xu, Jing Liu.
15. Exposure time versus cytotoxicity for anticancer agents
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Tác giả
David M. Evans, Jianwen Fang, Thomas Silvers.
15. Gemcitabine plus cisplatin versus fluorouracil plus cisplatin as a first-line concurrent chemotherapy regimen in nasopharyngeal carcinoma: a prospective, multi-institution, randomized controlled phase II study
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Tác giả
Xiang-Yun Kong, Jian-Xun Lu, Xin-Wen Yu, Jian Zhang.
15. Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5′-deoxy-5-fluorocytidine, 5′-deoxy-5-fluorouridine, and 5-fluorouracil
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Tác giả
Masae Sekido, Ken-ichi Fujita, Yutaro Kubota.
15. CDA and MTHFR polymorphisms are associated with clinical outcomes in gastroenteric cancer patients treated with capecitabine-based chemotherapy
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Tác giả
Duo Liu, Xiang Li, Xuehua Li, Mingyan Zhang.
15. Folate pathway genetic polymorphisms modulate methotrexate-induced toxicity in childhood acute lymphoblastic leukemia
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Tác giả
Al-Motassem Yousef, Rand Farhad, Daniah Alshamaseen.
15. Pharmacokinetics and bioequivalence of generic and branded abiraterone acetate tablet: a single-dose, open-label, and replicate designed study in healthy Chinese male volunteers
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Tác giả
Chunhua Wang, Chaoying Hu, Dan Gao, Zirun Zhao.
15. Safety of intraperitoneal paclitaxel combined with conventional chemotherapy for colorectal cancer with peritoneal carcinomatosis: a phase I trial
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Tác giả
Koji Murono, Hiroshi Nagata, Kazuhiro Ishimaru.
16. NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells
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Tác giả
Ling Liu, Jingjing Chen, Mengyao Cao, Jiangang Wang.
16. Adverse event profiles of ifosfamide-induced encephalopathy analyzed using the Food and Drug Administration Adverse Event Reporting System and the Japanese Adverse Drug Event Report databases
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Tác giả
Kazuyo Shimada, Shiori Hasegawa, Satoshi Nakao.
16. Pharmacokinetics and safety of erlotinib and its metabolite OSI-420 in infants and children with primary brain tumors
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Tác giả
Samuel J. Reddick, Olivia Campagne, Jie Huang.
16. Assessment of the effect of erdafitinib on cardiac safety: analysis of ECGs and exposure–QTc in patients with advanced or refractory solid tumors
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Tác giả
Elodie Valade, Anne-Gaëlle Dosne, Hong Xie.
16. Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysis
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Tác giả
Aurélie Pétain, Dafang Zhong, Xiaoyan Chen.
16. A phase 2 study to assess the pharmacokinetics and pharmacodynamics of CPX-351 and its effects on cardiac repolarization in patients with acute leukemias
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Tác giả
Tara L. Lin, Laura F. Newell, Robert K. Stuart.
16. Comparison of two different carboplatin and weekly paclitaxel schedule in elderly advanced non-small cell lung cancer patients
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Tác giả
Derya Kıvrak Salim, Tuğba Akın Telli.
16. A novel method to address the association between received dose intensity and survival outcome: benefits of approaching treatment intensification at a more individualised level in a trial of the European Osteosarcoma Intergroup
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Tác giả
Carlo Lancia, Jakob K. Anninga, Matthew R. Sydes.
16. Prognostic impact of polypharmacy and drug interactions in patients with advanced cancer
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Tác giả
Alexander Hoemme, Holger Barth, Manuel Haschke.
16. Anti-liver cancer effect and the mechanism of arsenic sulfide in vitro and in vivo
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Tác giả
Shudan Wang, Chao Zhang, Yumei Li, Ping Li.
16. Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA)
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Tác giả
Nathalie Rioux, Sherri Smith, Manav Korpal.
17. Combined thermo-chemotherapy of cancer using 1 MHz ultrasound waves and a cisplatin-loaded sonosensitizing nanoplatform: an in vivo study
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Tác giả
Rasoul Irajirad, Amirhossein Ahmadi.
17. Prophylactic administration of granulocyte colony-stimulating factor in epirubicin and cyclophosphamide chemotherapy for Japanese breast cancer patients: a retrospective study
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Tác giả
Takumi Sakurada, Sanako Bando, Yoshito Zamami.
17. Efficacy and safety of CT-P6 versus reference trastuzumab in HER2-positive early breast cancer: updated results of a randomised phase 3 trial
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Tác giả
F. J. Esteva, Y. V. Baranau, V. Baryash.
17. Is pathologic tumor regression grade after neo-adjuvant chemotherapy a promising prognostic indicator for patients with locally advanced gastric cancer? A cohort study evaluating tumor regression response
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Tác giả
Xing Xu, Guoliang Zheng, Tao Zhang, Yan Zhao.
17. The effects of lapatinib on cardiac repolarization: results from a placebo controlled, single sequence, crossover study in patients with advanced solid tumors
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Tác giả
Shodeinde A. Coker, Herbert I. Hurwitz.
17. Pharmacokinetics of trastuzumab emtansine (T-DM1) as a single agent or in combination with pertuzumab in HER2-positive breast cancer patients with recurrent or locally advanced metastatic breast cancer
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Tác giả
Dan Lu, Chunze Li, Matthew Riggs, Daniel Polhamus.
17. Pharmacokinetic and exploratory exposure–response analysis of pertuzumab in patients with operable HER2-positive early breast cancer in the APHINITY study
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Tác giả
Whitney P. Kirschbrown, Matts Kågedal, Bei Wang.
17. Pharmacokinetics and safety of olaparib tablets as monotherapy and in combination with paclitaxel: results of a Phase I study in Chinese patients with advanced solid tumours
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Tác giả
Peng Yuan, Jianzhong Shentu, Jianming Xu.
17. Cyclophosphamide dose adjustment based on body weight and albuminemia in elderly patients treated with R-mini-CHOP
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Tác giả
E. Baudry, S. Huguet, A. L. Couderc, P. Chaibi.
17. Targeting neratinib-induced diarrhea with budesonide and colesevelam in a rat model
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Tác giả
Kate R. Secombe, Imogen A. Ball, Joseph Shirren.
17. A dose-escalation study of docetaxel, oxaliplatin, and S-1 (DOS) as a first-line therapy for patients with unresectable metastatic gastric cancer
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Tác giả
Yasushi Sato, Tamotsu Sagawa, Hiroyuki Ohnuma.
18. A phase I delayed-start, randomized and pharmacodynamic study of metformin and chemotherapy in patients with solid tumors
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Tác giả
Mohammad Wasif Saif, Shrikar Rajagopal.
18. A phase I study evaluating combined nimotuzumab and neoadjuvant chemoradiotherapy followed by surgery in locally advanced esophageal cancer
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Tác giả
Saichun Qi, Ya Mao, Mingjun Jiang.
18. Pharmacokinetics of thiotepa in high-dose regimens for autologous hematopoietic stem cell transplant in Japanese patients with pediatric tumors or adult lymphoma
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Tác giả
Eisei Kondo, Takashi Ikeda, Hiroaki Goto.
18. The efficacy and safety of nab paclitaxel plus gemcitabine in elderly patients over 75 years with unresectable pancreatic cancer compared with younger patients
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Tác giả
Utako Ishimoto, Akiyoshi Kinoshita, Yuki Hirose.
18. Phase I study of ipatasertib as a single agent and in combination with abiraterone plus prednisolone in Japanese patients with advanced solid tumors
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Tác giả
Toshihiko Doi, Yutaka Fujiwara, Nobuaki Matsubara.
18. Long non-coding RNA GHET1 contributes to chemotherapeutic resistance to Gemcitabine in bladder cancer
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Tác giả
Bo Li, Dalon Xie, Hui Zhang.
18. Modeling long-term tumor growth and kill after combinations of radiation and radiosensitizing agents
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Tác giả
Tim Cardilin, Joachim Almquist, Mats Jirstrand.
18. TGFβ receptor inhibitor galunisertib is linked to inflammation- and remodeling-related proteins in patients with pancreatic cancer
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Tác giả
Davide Melisi, Rocio Garcia-Carbonero.
18. Phase I study of orally administered 14Carbon-isotope labelled-vistusertib (AZD2014), a dual TORC1/2 kinase inhibitor, to assess the absorption, metabolism, excretion, and pharmacokinetics in patients with advanced solid malignancies
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Tác giả
Alexander MacDonald, Graeme Scarfe, Dominic Magirr.
18. Increase in cetuximab-induced skin rash and hypomagnesemia in patients receiving concomitant treatment with proton pump inhibitors (PPIs): a possible drug interaction?
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Tác giả
Mahmoud Abu-Amna, Gil Bar-Sela.
18. Oral administration of irinotecan in patients with solid tumors: an open-label, phase I, dose escalating study evaluating safety, tolerability and pharmacokinetics
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Tác giả
I. Kümler, P. Grundtvig Sørensen, J. Palshof.
19. Cisplatin ototoxicity in children: risk factors and its relationship with polymorphisms of DNA repair genes ERCC1, ERCC2, and XRCC1
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Tác giả
Caner Turan, Mehmet Kantar, Çağdaş Aktan.
19. Pharmacokinetics and safety of neratinib during co-administration with loperamide in healthy subjects
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Tác giả
Kiana Keyvanjah, Blaire Cooke, David Martin.
19. FKBP12 is a predictive biomarker for efficacy of anthracycline-based chemotherapy in breast cancer
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Tác giả
Mingyou Xing, Jun Wang, Qin Yang, Yu Wang.
19. Intrapericardial carboplatin in the management of malignant pericardial effusion in breast cancer: a pilot study
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Tác giả
Mie Kotake, Hisao Imai, Kyoichi Kaira.
19. Predictive factors for the development of diabetes in cancer patients treated with phosphatidylinositol 3-kinase inhibitors
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Tác giả
Gyuri Kim, Myungeun Yoo, Min Hee Hong.
19. Renin–angiotensin system inhibitors for countering proteinuria induced by angiogenesis inhibitors: a retrospective observational analysis
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Tác giả
Toshinori Hirai, Yukari Shuji, Megumi Takiyama.
19. Phase II study to evaluate the efficacy of Trastuzumab in combination with Capecitabine and Oxaliplatin in first-line treatment of HER2-positive advanced gastric cancer: HERXO trial
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Tác giả
Fernando Rivera, C. Romero, P. Jimenez-Fonseca.
19. Pazopanib interacts with irinotecan by inhibiting UGT1A1-mediated glucuronidation, but not OATP1B1-mediated hepatic uptake, of an active metabolite SN-38
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Tác giả
Mariko Iwase, Ken-ichi Fujita, Yuki Nishimura.
19. d-dimer increase: an unfavorable factor for patients with primary liver cancer treated with TACE
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Tác giả
Xujiao Chen, Zhihui Chang, Zhaoyu Liu.
19. Phase 1b trial of nintedanib in combination with bevacizumab in patients with advanced solid tumors
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Tác giả
Ravi Paluri, Ankit Madan, Peng Li, Benjamin Jones.
19. Steroidal dimer by001 inhibits proliferation and migration of esophageal cancer cells via multiple mechanisms
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Tác giả
Sai-Qi Wang, Kai-Rui Zhou, Xiao-Li Shi, Hui-Fang Lv.
20. Population pharmacokinetic analysis of high-dose methotrexate in pediatric and adult oncology patients
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Tác giả
Sonoko Kawakatsu, Mina Nikanjam, Mark Lin, Sonny Le.
20. Downregulation of SRSF3 by antisense oligonucleotides sensitizes oral squamous cell carcinoma and breast cancer cells to paclitaxel treatment
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Tác giả
Yanan Sun, Lingyan Yan, Jihua Guo, Jun Shao.
20. Clinical difference between discontinuation and retreatment with nivolumab after immune-related adverse events in patients with lung cancer
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Tác giả
Atsuto Mouri, Kyoichi Kaira, Ou Yamaguchi.
20. Rituximab dosing in hematological malignancies: an old question, revisited
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Tác giả
Peter N. Morcos, Axel Boehnke, Nancy Valente.
20. MSI2-TGF-β/TGF-β R1/SMAD3 positive feedback regulation in glioblastoma
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Tác giả
Xingjun Jiang, Jun Tan, Yin Wen, Weidong Liu.
20. Clinical implications of an analysis of pharmacokinetics of crizotinib coadministered with dexamethasone in patients with non-small cell lung cancer
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Tác giả
Swan Lin, Dana J. Nickens, Maulik Patel.
20. Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer
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Tác giả
Roger M. Phillips, Paul M. Loadman, Guru Reddy.
20. Eligibility criteria for phase I clinical trials: tight vs loose?
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Tác giả
Laeeq Malik, David Lu.
20. ABCB1 c.3435C>T polymorphism is associated with platinum toxicity: a preliminary study
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Tác giả
Beatrice De Troia, Davide Dalu, Virginio Filipazzi.
20. The value of serum cystatin C in early evaluation of renal insufficiency in patients undergoing chemotherapy: a systematic review and meta-analysis
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Tác giả
Liyun He, Jine Li, Jinfeng Zhan, Fengming Yi.
20. Exposure–response relationship of olaratumab for survival outcomes and safety when combined with doxorubicin in patients with soft tissue sarcoma
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Tác giả
Robin L. Jones, Gary Mo, John R. Baldwin.
21. Metformin plus first-line chemotherapy versus chemotherapy alone in the treatment of epithelial ovarian cancer: a prospective open-label pilot trial
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Tác giả
Ya Zheng, Jie Zhu, Haiyan Zhang, Yanmei Liu.
21. A phase I study of HER1, HER2 dual kinase inhibitor lapatinib plus the proteasome inhibitor bortezomib in patients with advanced malignancies
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Tác giả
Filipa Lynce, Hongkun Wang, Emanuel F. Petricoin.
21. Prospective, observational practice survey of applied skin care and management of cetuximab-related skin reactions: PROSKIN study
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Tác giả
Sacha I. Rothschild, Daniel Betticher.
21. Correction to: Population pharmacokinetics of PF‑05280014 (a trastuzumab biosimilar) and reference trastuzumab (Herceptin®) in patients with HER2‑positive metastatic breast cancer
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Tác giả
Xiaoying Chen, Cheryl Li, Reginald Ewesuedo.
21. MicroRNA-552 deficiency mediates 5-fluorouracil resistance by targeting SMAD2 signaling in DNA-mismatch-repair-deficient colorectal cancer
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Tác giả
Ping Zhao, Yu-guang Ma, Yang Zhao, Di Liu.
21. Qualitative and quantitative variations in liver function thresholds among clinical trials in cancer: a need for harmonization
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Tác giả
Edwin Wang, Fei Song, Jessica K. Paulus.
21. FLAG vs FLAG-IDA: outcomes in relapsed/refractory acute leukemias
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Tác giả
Muhammad Umer Farooq, Fahad Mushtaq, Anum Farooq.
21. The clinical added value of the addition of anti-CTL-4 to anti-PD-1 alone is questionable and clearly increasing toxicity regarding pivotal studies in the treatment of melanoma and renal carcinoma
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Tác giả
Nicolas Albin, Adrien Monard, Jérémy Lapiere.
21. A successful compartmental approach for the treatment of breast cancer brain metastases
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Tác giả
Thuy T. Nguyen, Eurydice Angeli.
21. Real-world use of sunitinib in Japanese patients with pancreatic neuroendocrine tumors: results from a post-marketing surveillance study
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Tác giả
Kazuo Sato, Yasuharu Toyoshima, Shiho Moriyama.
22. Prevalence of the DPYD variant (Y186C) in Brazilian individuals of African ancestry
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Tác giả
Geraldo Felício Cunha-Junior.
22. Population pharmacokinetics of fedratinib in patients with myelofibrosis, polycythemia vera, and essential thrombocythemia
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Tác giả
Ken Ogasawara, Simon Zhou, Gopal Krishna.
22. An open label phase 1 study evaluation safety, tolerability, and maximum tolerated dose of oral administration of irinotecan in combination with capecitabine
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Tác giả
I. Kümler, R. L. Eefsen, Peter Grundtvig Sørensen.
22. Development of cutaneous squamous cell carcinoma after prolonged exposure to pegylated liposomal doxorubicin and hand–foot syndrome: a newly recognized toxicity
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Tác giả
Daniel F. Pease, Bruce A. Peterson, Scott Gilles.
22. Short-time use of crizotinib as neoadjuvant in ALK-positive non-small cell lung carcinoma can be a chance for resectability
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Tác giả
Saadettin Kilickap, Sevgen Onder, Omer Dizdar.
22. Neoadjuvant chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-RT) for locally advanced esophageal squamous cell carcinoma
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Tác giả
Ken Sasaki, Yasuto Uchikado, Itaru Omoto.
22. Lack of UGT polymorphism association with idasanutlin pharmacokinetics in solid tumor patients
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Tác giả
W. Venus So, Tai-Hsien Ou Yang, Xing Yang.
23. Correction to: Phase II study to evaluate the efficacy of Trastuzumab in combination with Capecitabine and Oxaliplatin in first-line treatment of HER2-positive advanced gastric cancer: HERXO trial
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Tác giả
Fernando Rivera, C. Romero, P. Jimenez-Fonseca.
23. A phase I trial of MK-2206 and hydroxychloroquine in patients with advanced solid tumors
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Tác giả
Janice M. Mehnert, Amanda D. Kaveney.
23. CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors
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Tác giả
Yogesh T. Patel, Abigail Davis, Suzanne J. Baker.
23. Efficacy of immunotherapy, gut microbiota and impact of antibiotic use: are there confounding factors?
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Tác giả
G. Milano.
23. A phase I trial of intraperitoneal nab-paclitaxel in the treatment of advanced malignancies primarily confined to the peritoneal cavity
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Tác giả
Mihaela C. Cristea, Paul Frankel, Timothy Synold.
23. Correction to: Aromatase inhibitor-induced carpal tunnel syndrome: prevalence in daily practice
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Tác giả
Soumaya Labidi, Nesrine Mejri, Houda El Benna.
24. A phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial)
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Tác giả
Jeffrey Melson Clarke, Gerard C. Blobe.
24. Stress resilience and survival among cancer patients: is there any absolute truth?
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Tác giả
Raffaella Mormile.
24. Inflammatory bowel disease associated with the combination treatment of nivolumab and metformin: data from the FDA adverse event reporting system
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Tác giả
Huaqiang Zhou, Jiaqing Liu, Yaxiong Zhang, Li Zhang.
25. A pilot study of first-line olaratumab, doxorubicin and ifosfamide in patients with metastatic soft tissue sarcoma
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Tác giả
Olga Vornicova, Nissim Haim, Gil Bar-Sela.