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Bioorganic Chemistry
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Volume 83 Pages 1-610 (March 2019)
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1. Editorial Board
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2. Issue TOC
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3. Bioactive monoterpene indole alkaloids from Nauclea officinalis
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Yan-Ping Liu, Qing-Long Liu, Xiang-Lin Zhang, Hai-Yuan Niu, ... Yan-Hui Fu.
4. Novel hybrids of benzothiazole-1,3,4-oxadiazole-4-thiazolidinone: Synthesis, in silico ADME study, molecular docking and in vivo anti-diabetic assessment
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Tác giả
Rubina Bhutani, Dharam Pal Pathak, Garima Kapoor, Asif Husain, Md. Azhar Iqbal.
5. New iridal-type triterpenoid derivatives with cytotoxic activities from Belamcanda chinensis
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Tác giả
Jiayuan Li, Gang Ni, Li Li, Yanfei Liu, ... Dequan Yu.
6. Biology-oriented drug synthesis (BIODS), in vitro urease inhibitory activity, and in silico study of S-naproxen derivatives
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Tác giả
Ghulam Mohiuddin, Khalid Mohammed Khan, Uzma Salar, Kanwal, ... Shahnaz Perveen.
7. Synthesis of new pyrazoles and pyrozolo [3,4-b] pyridines as anti-inflammatory agents by inhibition of COX-2 enzyme
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Tác giả
Lamia W. Mohamed, Mohamed A. Shaaban, Ashraf F. Zaher, Shimaa M. Alhamaky, Ayman M. Elsahar.
8. Synthesis of novel N-(1,3-thiazol-2-yl)benzamide clubbed oxadiazole scaffolds: Urease inhibition, Lipinski rule and molecular docking analyses
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Tác giả
Muhammad Athar Abbasi, Hussain Raza, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, ... Sung-Yum Seo.
9. bioNMR-based identification of natural anti-Aβ compounds in Peucedanum ostruthium
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Alessandro Palmioli, Sara Bertuzzi, Ada De Luigi, Laura Colombo, ... Cristina Airoldi
Nội dung
10. Design, synthesis, structural characterization and in vitro evaluation of new 1,4-disubstituted-1,2,3-triazole derivatives against glioblastoma cells
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Veronica D. da Silva, Bruna M. de Faria, Eduardo Colombo, Lucas Ascari, ... Camilla D. Buarque
Nội dung
11. Trichosanhemiketal A and B: Two 13,14-seco-13,14-epoxyporiferastanes from the root of Trichosanthes kirilowii Maxim
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Tác giả
Manh Tuan Ha, Thanh Nam Phan, Jeong Ah Kim, Won Keun Oh, ... Byung Sun Min.
Nội dung
12. Design, synthesis and molecular modeling study of certain VEGFR-2 inhibitors based on thienopyrimidne scaffold as cancer targeting agents
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Tác giả
Amna Ghith, Khairia M. Youssef, Nasser S.M. Ismail, Khaled A.M. Abouzid.
13. α-Pyrones, secondary metabolites from fungus Cephalotrichum microsporum and their bioactivities
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He Zhu, Dawei Li, Qingsong Yan, Yue An, ... Yixuan Zhang.
13. α-Pyrones, secondary metabolites from fungus Cephalotrichum microsporum and their bioactivities
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He Zhu, Dawei Li, Qingsong Yan, Yue An, ... Yixuan Zhang.
14. Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells
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Soo-Yeon Ahn, Mun Seok Jo, Dahae Lee, Seon-Eun Baek, ... Ki Hyun Kim
15. 2-Aryl-quinazolin-4(3H)-ones as an inhibitor of leishmania folate pathway: In vitro biological evaluation, mechanism studies and molecular docking
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Angel H. Romero, Noris Rodríguez, Henry Oviedo.
16. Preparation, characterization and in vitro activity of a docetaxel–albumin conjugate
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Jing Gao, Shougang Jiang, Xuewei Zhang, Yujie Fu, Zhiguo Liu.
17. Design and synthesis of novel quinazolinone-1,2,3-triazole hybrids as new anti-diabetic agents: In vitro α-glucosidase inhibition, kinetic, and docking study
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Mina Saeedi, Maryam Mohammadi-Khanaposhtani, Parvaneh Pourrabia, Nima Razzaghi, ... Tahmineh Akbarzadeh.
18. Synthesis of 1,2,4-triazole-5-on derivatives and determination of carbonic anhydrase II isoenzyme inhibition effects
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Safak Akin, Hasan Ayaloglu, Ergun Gultekin, Ahmet Colak, ... Melike Yildirim Akatin.
19. In vitro activities of a new fluoroquinolone derivative highly active against Chlamydia trachomatis
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Thi Huyen Vu, Nguyet-Thanh Ha-Duong, Alexandra Aubry, Estelle Capton, ... Nawal Serradji.
20. Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors
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Riham F. George, Eman M. Samir, Mennatullah N. Abdelhamed, Hatem A. Abdel-Aziz, Safinaz E-S. Abbas.
Nội dung
21. 4-Substituted benzenesulfonamides featuring cyclic imides moieties exhibit potent and isoform-selective carbonic anhydrase II/IX inhibition
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Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Adel H. Ghiaty, Paola Gratteri, ... Alessio Nocentini.
22. Understanding the cytotoxic effects of new isovanillin derivatives through phospholipid Langmuir monolayers
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Ana C. de Carvalho, Natália Girola, Carlos R. de Figueiredo, André C. Machado, ... Thiago A.M. Veiga.
23. A novel bi-functional chalcone inhibits multi-drug resistant Staphylococcus aureus and potentiates the activity of fluoroquinolones
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Vivek Kumar Gupta, Rashmi Gaur, Atin Sharma, Jawed Akther, ... Ranjana Pathania.
24. Synthesis and 2D-QSAR study of dispiropyrrolodinyl-oxindole based alkaloids as cholinesterase inhibitors
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Tác giả
Aladdin M. Srour, Dina H. Dawood, Mohammed N.A. Khalil, Zienab M. Nofal.
25. Carbazole and hydrazone derivatives as new competitive inhibitors of tyrosinase: Experimental clues to binuclear copper active site binding
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Tác giả
Usman Ghani.
26. Synthesis and evaluation of an AZD2461 [18F]PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant
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Sean W. Reilly, Laura N. Puentes, Alexander Schmitz, Chia-Ju Hsieh, ... Robert H. Mach.
27. New benzimidazothiazole derivatives as anti-inflammatory, antitumor active agents: Synthesis, in-vitro and in-vivo screening and molecular modeling studies
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Tác giả
Mohamed M. El-Kerdawy, Mariam A. Ghaly, Sara A. Darwish, Hatem A. Abdel-Aziz, ... Ghada S. Hassan.
28. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile
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Tác giả
Omneya M. Khalil, Ehab M. Gedawy, Afaf A. El-Malah, Mina E. Adly.
29. Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors
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Zhi-Qiang Cheng, Kong-Kai Zhu, Juan Zhang, Jia-Li Song, ... Hua Zhang.
30. Synthesis, in vitro urease inhibition and molecular docking studies of some novel quinazolin-4(3H)-one derivatives containing triazole, thiadiazole and thiosemicarbazide functionalities
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Tác giả
Emre Menteşe, Gülay Akyüz, Mustafa Emirik, Nimet Baltaş.
31. Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer’s compounds: In vitro and in vivo biological evaluation and docking study
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Tác giả
Zahra Najafi, Mohammad Mahdavi, Mina Saeedi, Elahe Karimpour-Razkenari, ... Tahmineh Akbarzadeh.
32. Rhamnocitrin isolated from Prunus padus var. seoulensis: A potent and selective reversible inhibitor of human monoamine oxidase A
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Tác giả
Seung Cheol Baek, Mi Hyeon Park, Hyung Won Ryu, Jae Pil Lee, ... Hoon Kim.
33. vChemical fabrication of graphene oxide nanosheets attenuates biofilm formation of human clinical pathogens
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Tác giả
Vaikundamoorthy Ramalingam, Sakthivel Raja, Subramaniam Sundaramahalingam, Rajendran Rajaram.
34. Design, synthesis and bioevaluation of tricyclic fused ring system as dual binding site acetylcholinesterase inhibitors
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Saba Tahir Tanoli, Muhammad Ramzan, Abbas Hassan, Abdul Sadiq, ... Umer Rashid.
35. Antileishmanial activity and ultrastructural changes of sesquiterpene lactones isolated from Calea pinnatifida (Asteraceae)
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Tác giả
Lhaís Araújo Caldas, Meire L. Yoshinaga, Marcelo J.P. Ferreira, João H.G. Lago, ... Patricia Sartorelli.
36. Design, synthesis and pharmacological evaluation of some substituted dihydropyrimidines with L-/T-type calcium channel blocking activities
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Tác giả
Mohamed Teleb, Ola H. Rizk, Fang-Xiong Zhang, Frank R. Fronczek, ... Hesham Fahmy.
37. Novel 4-(3-phenylpropionamido), 4-(2-phenoxyacetamido) and 4-(cinnamamido) substituted benzamides bearing the pyrazole or indazole nucleus: synthesis, biological evaluation and mechanism of action
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Demetrio Raffa, Antonella D'Anneo, Fabiana Plescia, Giuseppe Daidone, ... Benedetta Maggio.
38. Discovery of novel quinazolines as potential anti-tubulin agents occupying three zones of colchicine domain
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Wenlong Li, Ying Yin, Wen Shuai, Feijie Xu, ... Shengtao Xu.
39. Design, synthesis and anti-Alzheimer’s activity of novel 1,2,3-triazole-chromenone carboxamide derivatives
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Arezoo Rastegari, Hamid Nadri, Mohammad Mahdavi, Alireza Moradi, ... Mina Saeedi.
39. Design, synthesis and anti-Alzheimer’s activity of novel 1,2,3-triazole-chromenone carboxamide derivatives
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Arezoo Rastegari, Hamid Nadri, Mohammad Mahdavi, Alireza Moradi, ... Mina Saeedi.
40. Synthesis, and anti-proliferative, Pim-1 kinase inhibitors and molecular docking of thiophenes derived from estrone
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Rafat M. Mohareb, Eman M. Samir, Peter A. Halim.
41. Synthesis and carbonic anhydrase inhibitory properties of novel 4-(2-aminoethyl)benzenesulfonamide-dipeptide conjugates
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Hasan Küçükbay, Nesrin Buğday, F. Zehra Küçükbay, Emanuela Berrino, ... Claudiu T. Supuran.
42. Synthesis and biological evaluation of pyrano[4,3-b][1]benzopyranone derivatives as monoamine oxidase and cholinesterase inhibitors
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Koichi Takao, Yuka Kubota, Hitoshi Kamauchi, Yoshiaki Sugita.
43. Design, synthesis, and biological activities of 1-aryl-(3-(2-styryl)phenyl)prop-2-en-1-ones
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Soon Young Shin, Junho Lee, Jihyun Park, Youngshim Lee, ... Yoongho Lim.
44. Novel dauricine derivatives suppress cancer via autophagy-dependent cell death
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Xiaobo Zhou, Yuan Qing Qu, Zhiyuan Zheng, Betty Yuen Kwan Law, ... Li-Ping Bai.
45. Introduction of Z-GP scaffold into procarbazine reduces spermatoxicity and myelosuppression
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Rikang Wang, Chao Zhang, Chaojun Zheng, Huilan Li, ... Heru Chen.
46. Neuroprotective effects of triterpenoid saponins from Medicago sativa L. against H2O2-induced oxidative stress in SH-SY5Y cells
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Xue-Gui Liu, Yu-Qiu Sun, Jun Bian, Ting Han, ... Pin-Yi Gao.
47. Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer’s disease
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Tác giả
Juan Wang, Wei Li, Jingfang Qin, Li Wang, ... Huang Tang.
48. Proliferation inhibition of novel diphenylamine derivatives
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Ladislav Janovec, Jana Janočková, Mária Matejová, Eva Konkoľová, ... Mária Kožurková.
49. Potential bioisosteres of β-uracilalanines derived from 1H-1,2,3-triazole-C-carboxylic acids
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Ewa Mironiuk-Puchalska, Włodzimierz Buchowicz, Piotr Grześkowiak, Patrycja Wińska, ... Mariola Koszytkowska-Stawińska.
50. Design, synthesis and in vitro apoptotic mechanism of novel pyrrolopyrimidine derivatives
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Zühal Kilic-Kurt, Filiz Bakar-Ates, Yeliz Aka, Ozgur Kutuk.
51. Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors
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Kuang-Feng Chu, Jen-Shin Song, Chiung-Tong Chen, Teng-Kuang Yeh, ... Jinq-Chyi Lee.
52. Synthesis and biological evaluation of new quinoline derivatives as antileishmanial and antitrypanosomal agents
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Santiago N. Chanquia, Facundo Larregui, Vanesa Puente, Carlos Labriola, ... Guadalupe García Liñares.
53. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents
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Budaganaboyina Prasad, V. Lakshma Nayak, P.S. Srikanth, Mirza Feroz Baig, ... Ahmed Kamal.
54. SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX
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Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Emanuela Berrino, Daniela Vullo, ... Claudiu T. Supuran.
55. Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer’s agents
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Naeimeh Salehi, Bi Bi Fatemeh Mirjalili, Hamid Nadri, Zahra Abdolahi, ... Mehdi Khoobi.
56. Synthesis and evaluation of new 4-oxoquinazolin-3(4H)-yl)benzoic acid and benzamide derivatives as potent antibacterial agents effective against multidrug resistant Staphylococcus aureus
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Srikanth Gatadi, Jitendra Gour, Manjulika Shukla, Grace Kaul, ... Srinivas Nanduri.
57. Synthesis and biological evaluation of new 2,4,6-trisubstituted pyrimidines and their N-alkyl derivatives
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Nuran Kahriman, Vildan Serdaroğlu, Kıvanç Peker, Ali Aydın, ... Nurettin Yaylı.
58. Syntheses, in vitro urease inhibitory activities of urea and thiourea derivatives of tryptamine, their molecular docking and cytotoxic studies
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Kanwal, Majid Khan, Arshia, Khalid Mohammed Khan, ... M. Iqbal Choudhary.
59. Synthesis, characterization, crystal structure of the coordination polymer Zn(II) with thiosemicarbazone of glyoxalic acid and their inhibitory properties against some metabolic enzymes
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Mansura Huseynova, Ajdar Medjidov, Parham Taslimi, Mahizar Aliyeva.
60. Antibacterial activity against drug-resistant microbial pathogens of cytochalasan alkaloids from the arthropod-associated fungus Chaetomium globosum TW1-1
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Weixi Gao, Yan He, Fengli Li, Chenwei Chai, ... Yonghui Zhang.
61. Synthesis and DNA binding profile of monomeric, dimeric, and trimeric derivatives of crystal violet
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Omar Nuñez, Bianca Chavez, Ryan Shaktah, Paola Pereda Garcia, Thomas Minehan.
62. Synthesis of N-benzyl substituted 1,4-imino-l-lyxitols with a basic functional group as selective inhibitors of Golgi α-mannosidase IIb
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Tomáš Klunda, Sergej Šesták, Juraj Kóňa, Monika Poláková.
