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Bioorganic Chemistry
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Volume 82 Pages 1-430 (February 2019)
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1. Editorial Board
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Nội dung
Page i
2. Issue TOC
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Nội dung
Jun He, Jie-kun Xu, Xue-ge Pan, Xian-sheng Ye, ... Wei-ku Zhang
Pages 1-5
3. Unusual cadinane-type sesquiterpene glycosides with α-glucosidase inhibitory activities from the fruit of Cornus officinalis Sieb. et Zuuc.
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Tác giả
Jun He, Jie-kun Xu, Xue-ge Pan, Xian-sheng Ye, ... Wei-ku Zhang.
4. Acridine-based (thio)semicarbazones and hydrazones: Synthesis, in vitro urease inhibition, molecular docking and in-silico ADME evaluation
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Tác giả
Ibanga Okon Isaac, Mariya al-Rashida, Shafiq Ur Rahman, Rima D. Alharthy, ... Jamshed Iqbal.
5. How the surface functionalized nanoparticles affect conformation and activity of proteins: Exploring through protein-nanoparticle interactions
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Tác giả
Sathish Dyawanapelly, Pihu Mehrotra, Goutam Ghosh, Dhanashree D Jagtap, ... Ratnesh Jain.
6. Bioactive staurosporine derivatives from the Streptomyces sp. NB-A13
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Tác giả
Biao Zhou, Zhi-Juan Hu, Hao-Jian Zhang, Jia-Qi Li, ... Zhong-Jun Ma.
7. Identification and Structure–Activity Relationship (SAR) of potent and selective oxadiazole-based agonists of sphingosine-1-phosphate receptor (S1P1)
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Tác giả
Tianqi Liu, Jing Jin, Yonghui Chen, Qiumu Xi, ... Dali Yin.
8. Lead compounds and key residues of ribosomal protein S1 in drug-resistant Mycobacterium tuberculosis
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Tác giả
Yunbao Zhi, Yazhuang Dai, Juanjuan Yang, Shuhua Tan, ... Kejiang Lin.
9. The isolation, absolute configuration and activities of 18(4 → 3)-abeo-abietane lactones from Tripterygium wilfordii
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Tác giả
Lin Ni, Li Li, Yingda Zang, Chuang-jun Li, ... Dong-ming Zhang.
10. Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target
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Tác giả
Tomáš Bříza, Jarmila Králová, Silvie Rimpelová, Martin Havlík, ... Vladimír Král.
11. Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors
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Tác giả
Khaled R.A. Abdellatif, Wael A.A. Fadaly, Gehan M. Kamel, Yaseen A.M.M. Elshaier, Mohammed A. El-Magd.
12. Design, synthesis and biological evaluation of N1-(isoquinolin-5-yl)-N2-phenylpyrrolidine-1,2-dicarboxamide derivatives as potent TRPV1 antagonists
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Tác giả
Mingxiang Gao, Cunbin Nie, Jinyu Li, Beibei Song, ... Hai Qian.
13. 1,2,4-Trisubstituted imidazolinones with dual carbonic anhydrase and p38 mitogen-activated protein kinase inhibitory activity
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Tác giả
Hanan H. Georgey, Fatma M. Manhi, Walaa R. Mahmoud, Nehad A. Mohamed, ... Claudiu T. Supuran.
14. Design, synthesis and biological evaluation of novel ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as potent carbonic anhydrase IX inhibitors
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Tác giả
Nabih Lolak, Suleyman Akocak, Silvia Bua, Claudiu T. Supuran.
15. Design and synthesis of novel potent anticoagulant and anti-tyrosinase pyranopyrimidines and pyranotriazolopyrimidines: Insights from molecular docking and SAR analysis
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Tác giả
Meriem Debbabi, Vijaykumar D. Nimbarte, Samia Chekir, Sarra Chortani, ... Hichem Ben jannet.
16. Six new compounds from the flowers of Chrysanthemum morifolium and their biological activities
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Tác giả
Peng-Fei Yang, Ya-Nan Yang, Zi-Ming Feng, Jian-Shuang Jiang, Pei-Cheng Zhang.
17. Design, and facile synthesis of 1,3 diaryl-3-(arylamino)propan-1-one derivatives as the potential alpha-amylase inhibitors and antioxidants
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Tác giả
Roqia Bashary, Gopal L. Khatik.
18. Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and kinetic studies
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Azhar Abbas, Basharat Ali, Kanwal, Khalid Mohammed Khan, ... Shahnaz Perveen.
19. α-Tocopherol-ascorbic acid hybrid antioxidant based cationic amphiphile for gene delivery: Design, synthesis and transfection
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Venkanna Muripiti, Lohchania Brijesh, Hari Krishnareddy Rachamalla, Srujan Kumar Marepally, ... Srilakshmi V. Patri.
20. Hydrogen sulfide releasing enmein-type diterpenoid derivatives as apoptosis inducers through mitochondria-related pathways
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Tác giả
Fanxing Xu, Xiang Gao, Haonan Li, Shengtao Xu, ... Dahong Li.
21. Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity
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Monika Pospisilova, Martin Andrs, Martina Seifrtova, Radim Havelek, ... Martina Rezacova.
22. Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer’s disease
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Tác giả
Sushant K. Shrivastava, Saurabh K. Sinha, Pavan Srivastava, Prabhash N. Tripathi, ... Rakesh K. Srivastava.
23. Antimicrobial and antibiofilm activity of polyurethane/Hypericum perforatum extract (PHPE) composite
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Tác giả
Okay Nazlı, Tuba Baygar, Çiğdem Elif Demirci Dönmez, Özcan Dere, ... Selçuk Aktürk.
24. Rationally designed molecules for resurgence of cyanide mitigated cytochrome c oxidase activity
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Tác giả
Harpreet Kaur, Palwinder Singh.
25. In vitro biological evaluation and molecular docking studies of natural and semisynthetic flavones from Gardenia oudiepe (Rubiaceae) as tyrosinase inhibitors
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Tác giả
M.D. Santi, C. Bouzidi, N.S. Gorod, M. Puiatti, ... M.G. Ortega.
26. α-Sulfonamidophosphonates as new anti-mycobacterial chemotypes: Design, development of synthetic methodology, and biological evaluation
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Tác giả
Srikant Bhagat, Metheku Supriya, Satish Pathak, Dharmarajan Sriram, Asit K. Chakraborti.
27. Schiff bases of tryptamine as potent inhibitors of nucleoside triphosphate diphosphohydrolases (NTPDases): Structure-activity relationship
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Tác giả
Kanwal, Khalid Mohammed Khan, Uzma Salar, Saira Afzal, ... Jamshed Iqbal.
28. Imidazole-pyrazole hybrids: Synthesis, characterization and in-vitro bioevaluation against α-glucosidase enzyme with molecular docking studies
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Tác giả
Faryal Chaudhry, Sadia Naureen, Muhammad Ashraf, Mariya Al-Rashida, ... Misbahul Ain Khan.
29. Bioactive scalemic caged xanthones from the leaves of Garcinia bracteata
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Tác giả
Bao-Jun Zhang, Wen-Wei Fu, Rong Wu, Jin-Ling Yang, ... Hong-Xi Xu.
30. NMR fragment-based screening for development of the CD44-binding small molecules
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Marcin Pustuła, Mirosława Czub, Beata Łabuzek, Ewa Surmiak, ... Tad A. Holak.
31. Design, synthesis and biological evaluation of fused naphthofuro[3,2-c] quinoline-6,7,12-triones and pyrano[3,2-c]quinoline-6,7,8,13-tetraones derivatives as ERK inhibitors with efficacy in BRAF-mutant melanoma
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Ashraf A. Aly, Essmat M. El-Sheref, Momtaz E.M. Bakheet, Mai A.E. Mourad, ... Tamer S. Kaoud.
32. Design, synthesis, anti-inflammatory, cytotoxic and cell based studies of some novel side chain analogues of myrrhanones A & B isolated from the gum resin of Commiphora mukul
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Tác giả
Uppuluri Venkata Mallavadhani, Madasu Chandrashekhar, Karri Shailaja, Sistla Ramakrishna.
33. Pyranopyrazoles as efficient antimicrobial agents: Green, one pot and multicomponent approach
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Guda Mallikarjuna Reddy, Jarem Raul Garcia, Grigory V. Zyryanov, Gundala Sravya, Nemallapudi Bakthavatchala Reddy.
34. A deuterohemin peptide protects a transgenic Caenorhabditis elegans model of Alzheimer’s disease by inhibiting Aβ1–42 aggregation
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Tác giả
Jia Xu, Ye Yuan, Ruining Zhang, Yanhui Song, ... Liping Wang.
35. Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activity
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Tác giả
Nevine M.Y. Elsayed, Rabah A.T. Serya, Mai F. Tolba, Marawan Ahmed, ... Khaled A.M. Abouzid.
36. New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity
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Samar H. Abbas, Amer Ali Abd El-Hafeez, Mai E. Shoman, Monica M. Montano, Heba A. Hassan.
37. Resistance modulatory and efflux-inhibitory activities of capsaicinoids and capsinoids
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Sandra Prasch, Alexandra G. Duran, Nuria Chinchilla, José M.G. Molinillo, ... Franz Bucar.
38. New antibacterial and 5-lipoxygenase activities of synthetic benzyl phenyl ketones: Biological and docking studies
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Yesseny Vásquez-Martínez, Claudia Torrent, Giannina Toledo, Francisco Cabezas, ... Carolina Mascayano.
39. Synthesis, characterization, crystal structure of novel bis-thiomethylcyclohexanone derivatives and their inhibitory properties against some metabolic enzymes
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Tác giả
Abdullah Biçer, Parham Taslimi, Gül Yakalı, Ilhami Gülçin, ... Günseli Turgut Cin.
40. Side-chain cleaved phytoecdysteroid metabolites as activators of protein kinase B
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Halima Meriem Issaadi, József Csábi, Tusty-Jiuan Hsieh, Tamás Gáti, ... Attila Hunyadi.
41. 1,2,3-Triazole-based kojic acid analogs as potent tyrosinase inhibitors: Design, synthesis and biological evaluation
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Morteza Ashooriha, Mehdi Khoshneviszadeh, Mahsima Khoshneviszadeh, Seyed Ershad Moradi, ... Saeed Emami.
42. Synthesis of new thiazolo-pyrrolidine–(spirooxindole) tethered to 3-acylindole as anticancer agents
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Mohammad Shahidul Islam, Hussien Mansur Ghawas, Fardous F. El-Senduny, Abdullah Mohammed Al-Majid, ... Assem Barakat.
43. Dioximes: Synthesis and biomedical applications
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Tác giả
Mohamed A. Motaleb, Adli A. Selim.
44. Bioactivity-based analysis and chemical characterization of anti-inflammatory compounds from Curcuma zedoaria rhizomes using LPS-stimulated RAW264.7 cells
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Tae Kyoung Lee, Tuy An Trinh, Seoung Rak Lee, Sil Kim, ... Ki Hyun Kim.
45. 3-Aminobenzenesulfonamides incorporating acylthiourea moieties selectively inhibit the tumor-associated carbonic anhydrase isoform IX over the off-target isoforms I, II and IV
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Tác giả
Tanzeela Abdul Fattah, Silvia Bua, Aamer Saeed, Ghulam Shabir, Claudiu T. Supuran.
