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Mechanisms of Ageing and Development
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1. Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories
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Jaana van Gastel, Huan Cai, Wei-Na Cong, Wayne Chadwick, ... Stuart Maudsley.
1. Interferons: A molecular switch between damage and repair in ageing and Alzheimer’s disease
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Tác giả
N. Gorlé, R.E. Vandenbroucke.
1. Spelunking the biology of frailty
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Alice E. Kane, Susan E. Howlett.
1. Biology of frailty: Implications for clinical pharmacology and drug therapy in frail older people
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Sarah N. Hilmer, Harry Wu, Meggie Zhang.
1. Geroprotectors: A role in the treatment of frailty
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A.U. Trendelenburg, A.C. Scheuren, P. Potter, R. Müller, I. Bellantuono.
1. Cell cycle arrest in replicative senescence is not an immediate consequence of telomere dysfunction
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M.Shamim Nassrally, Ashley Lau, Katherine Wise, Noah John, ... Robert F. Brooks.
1. Retraction notice to
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Qi Zhu, Linsheng Huang, Jian Zhu, Jianquan Lu, Huanlong Qin.
1. Where ageing goes nowadays: Mechanisms, pathways, biomarkers and anti-ageing strategies
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Efstathios S. Gonos, Niki Chondrogianni, Aleksandra Mladenovic Djordjevic.
2. NF-κB signaling in skin aging
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Yujia Wang, Lian Wang, Xiang Wen, Dan Hao, ... Xian Jiang.
2. Feed-forward loop between body composition, strength and performance in older adults
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Arindam RoyChoudhury, Thuy-Tien L. Dam, Chenghuiyun Xu, Jonathan H. Diah, ... Linda P. Fried.
2. Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice
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Allen Herbst, Austin N. Hoang, Wendy Woo, Debbie McKenzie, ... Jonathan Wanagat.
2. Role of frailty in the assessment of cognitive functioning
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Marco Canevelli, Matteo Cesari, Riccardo Raganato, Federica Trentin, ... Giuseppe Bruno.
2. Age and frailty as risk factors for the development of osteoarthritis
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Melissa S. O’Brien, Jason J. McDougall.
2. Comparative analysis of the gut microbiota in centenarians and young adults shows a common signature across genotypically non-related populations
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Ngangyola Tuikhar, Santosh Keisam, Rajendra Kumar Labala, Imrat, ... Kumaraswamy Jeyaram.
2. Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview
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Babatunde Fariyike, Quante Singleton, Monte Hunter, William D. Hill, ... Sadanand Fulzele.
2. Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics
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Martin S. Denzel, Louis R. Lapierre, Hildegard I.D. Mack.
3. Changes of the coronary arteries and cardiac microvasculature with aging: Implications for translational research and clinical practice
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Francesco Piccirillo, Myriam Carpenito, Giuseppe Verolino, Camilla Chello, ... Antonio Nenna.
3. Telomere length and physical performance among older people—The Helsinki Birth Cohort Study
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Max J. Åström, Mikaela B. von Bonsdorff, Mia-Maria Perälä, Minna K. Salonen, ... Johan G. Eriksson.
3. When will my mouse die? Life span prediction based on immune function, redox and behavioural parameters in female mice at the adult age
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Irene Martínez de Toda, Carmen Vida, Luis Sanz San Miguel, Mónica De la Fuente.
3. Attenuation of frailty in older adults with mesenchymal stem cells
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Victoria Florea, Luiza Bagno, Angela C. Rieger, Joshua M. Hare.
3. The impact of physical activity and sedentary behaviors on frailty levels
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Dustin Scott Kehler, Olga Theou.
3. Functional genomics of dietary restriction and longevity in yeast
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Sergio E. Campos, Alexander DeLuna.
3. Circular RNA involvement in aging: An emerging player with great potential
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Hongcai Cai, Yamin Li, Jean Damascene Niringiyumukiza, Ping Su, Wenpei Xiang.
3. Oxaloacetate decarboxylase FAHD1 – a new regulator of mitochondrial function and senescence
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Solmaz Etemad, Michèle Petit, Alexander K.H. Weiss, Andre Schrattenholz, ... Pidder Jansen-Dürr.
4. Extracellular vesicles as an emerging tool for the early detection of Alzheimer’s disease
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Tao-Ran Li, Xiao-Ni Wang, Can Sheng, Yu-Xia Li, ... Ying Han.
4. Classical monocytes from older adults maintain capacity for metabolic compensation during glucose deprivation and lipopolysaccharide stimulation
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Johnathan R. Yarbro, Brandt D. Pence.
4. Selective brain neuronal and glial losses without changes in GFAP immunoreactivity: Young versus mature adult Wistar rats
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Leonardo D. Diene, Zaquer S.M. Costa-Ferro, Silvia Barbosa, Bruna Bueno Milanesi, ... Léder L. Xavier.
4. Knockdown of the neuronal gene Lim3 at the early stages of development affects mitochondrial function and lifespan in Drosophila
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Olga Y. Rybina, Mikhail I. Schelkunov, Ekaterina R. Veselkina, Svetlana V. Sarantseva, ... Elena G. Pasyukova.
4. Frailty index as a biomarker of lifespan and healthspan: Focus on pharmacological interventions
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Dushani L. Palliyaguru, Jacqueline M. Moats, Clara Di Germanio, Michel Bernier, Rafael de Cabo.
4. Brain region-specific effects of long-term caloric restriction on redox balance of the aging rat
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Tác giả
Emmanuel Moyse, Madeleine Arsenault, Pierrette Gaudreau, Guylaine Ferland, Charles Ramassamy.
4. Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis
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Zewu Zhu, Weiping Xia, Yu Cui, Feng Zeng, ... Chen Hequn.
4. SOX2 expression diminishes with ageing in several tissues in mice and humans
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Estefania Carrasco-Garcia, Leire Moreno-Cugnon, Idoia Garcia, Consuelo Borras, ... Ander Matheu.
5. Desmoglein-3 acts as a pro-survival protein by suppressing reactive oxygen species and doming whilst augmenting the tight junctions in MDCK cells
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Xiao Li, Usama Sharif Ahmad, Yunying Huang, Jutamas Uttagomol, ... H Wan.
5. Glycoanalysis of the placental membrane glycoproteins throughout placental development
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Dragana Robajac, Romana Masnikosa, Marek Nemčovič, Martina Križáková, ... Olgica Nedić.
5. The synergistic action of phosphate and interleukin-6 enhances senescence-associated calcification in vascular smooth muscle cells depending on p53
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Tác giả
Deping Xu, Fanjun Zeng, Linzi Han, Jun Wang, ... Haisheng Zhou.
5. Emerging senolytic agents derived from natural products
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Wen Li, Lin Qin, Rennan Feng, Guangrong Hu, ... Rongping Zhang.
5. High intensity interval training improves physical performance in aged female mice: A comparison of mouse frailty assessment tools
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Kenneth Ladd Seldeen, Yonas Z. Redae, Ramkumar Thiyagarajan, Reem Nagi Berman, ... Bruce Robert Troen.
5. Transcriptome profiling of human papillary and reticular fibroblasts from adult interfollicular dermis pinpoints the ‘tissue skeleton’ gene network as a component of skin chrono-ageing
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Tác giả
Valérie Haydont, Véronique Neiveyans, Nicolas O. Fortunel, Daniel Asselineau.
5. Apolipoprotein E gene in physiological and pathological aging
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E. Ferri, C. Gussago, M. Casati, D. Mari, ... B. Arosio.
5. The impact of oxidative DNA damage and stress on telomere homeostasis
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Tác giả
Ryan P. Barnes, Elise Fouquerel, Patricia L. Opresko.
6. Neuroglial patterns are shared by cerebella from prion and prion-like disorder affected patients
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Moisés Garcés, M. Isabel Guijarro, Antonia Vargas, Juan J. Badiola, Marta Monzón.
6. Regulation of cellular senescence by retinoid X receptors and their partners
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6. Inflamm-aging microRNAs may integrate signals from food and gut microbiota by modulating common signalling pathways
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Laura Teodori, Ilaria Petrignani, Angelica Giuliani, Francesco Prattichizzo, ... Maria Cristina Albertini.
6. Crucial players in Alzheimer’s disease and diabetes mellitus: Friends or foes?
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Tác giả
AM. Kubis-Kubiak, A. Rorbach-Dolata, A. Piwowar.
6. Sublethal whole-body irradiation causes progressive premature frailty in mice
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Tác giả
Edward Fielder, Melanie Weigand, Julien Agneessens, Brigid Griffin, ... Thomas von Zglinicki.
6. Rodent models of frailty and their application in preclinical research
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Tác giả
Shubham Banga, Stefan D. Heinze-Milne, Susan E. Howlett.
6. Klotho gene polymorphisms are associated with healthy aging and longevity: Evidence from a meta-analysis
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Tác giả
Zewu Zhu, Weiping Xia, Yu Cui, Feng Zeng, ... Chen Hequn.
6. Protein aggregates and proteostasis in aging: Amylin and β-cell function
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Michaela Press, Tobias Jung, Jeannette König, Tilman Grune, Annika Höhn.
7. Ischemic stroke in neonatal and adult astrocytes
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Miren Revuelta, Amaia Elicegui, Leire Moreno-Cugnon, Christoph Bührer, ... Thomas Schmitz.
7. Prognostic networks for unraveling the biological mechanisms of Sarcopenia
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Ana Cernea, Juan Luis Fernández-Martínez, Enrique Juan de Andrés-Galiana, Zulima Fernández-Muñiz, ... Beatriz Caballero.
7. Modulation of frailty syndrome by diet: A review of evidence from mouse studies
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Tác giả
Sarah J. Mitchell, Gareth J. Mitchell, James R. Mitchell.
7. Do sex differences in chronic disease underpin the sex-frailty paradox?
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Tác giả
E.H. Gordon, R.E. Hubbard.
7. Apolipoprotein E gene in physiological and pathological aging
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Tác giả
E. Ferri, C. Gussago, M. Casati, D. Mari, ... B. Arosio.
7. Linker histones and chromatin remodelling complexes maintain genome stability and control cellular ageing
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George Miloshev, Dessislava Staneva, Katya Uzunova, Bela Vasileva, ... Milena Georgieva.
8. Replicative senescence is distinguishable from DNA damage-induced senescence by increased methylation of promoter of rDNA and reduced expression of rRNA
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Tác giả
Reiko Sanokawa-Akakura, Shin Akakura, Elena A. Ostrakhovitch, Siamak Tabibzadeh.
8. Chromosomal instability and pro-inflammatory response in aging
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Tác giả
Monika Barroso-Vilares, Elsa Logarinho.
8. Age-related deficit accumulation and the diseases of ageing
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Tác giả
Kenneth Rockwood, Susan E. Howlett.
8. Resistin: A reappraisal
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Tác giả
E. Acquarone, F. Monacelli, R. Borghi, A. Nencioni, P. Odetti.
8. The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature
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Tác giả
Maria De Luca.
9. Frailty biomarkers in humans and rodents: Current approaches and future advances
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Tác giả
Alice E. Kane, David A. Sinclair.
9. Glycation interferes with natural killer cell function
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Tác giả
Philip Rosenstock, Veronika Bezold, Kaya Bork, Jonas Scheffler, Rüdiger Horstkorte.
9. Role of hypothalamus in aging and its underlying cellular mechanisms
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Tác giả
Keetae Kim, Han Kyoung Choe.
10. Circulating miR-146a in healthy aging and type 2 diabetes: Age- and gender-specific trajectories
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Tác giả
Emanuela Mensà, Angelica Giuliani, Giulia Matacchione, Felicia Gurău, ... Fabiola Olivieri.
10. Tauopathy: A common mechanism for neurodegeneration and brain aging
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Tác giả
Pampa Saha, Nilkantha Sen.
10. To adapt or not to adapt: Consequences of declining Adaptive Homeostasis and Proteostasis with age
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Laura C.D. Pomatto, Patrick Y. Sun, Kelvin J.A. Davies.
11. Astragaloside IV and ferulic acid synergistically promote neurite outgrowth through Nrf2 activation
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Yini Liang, Yu Zou, Chengu Niu, Yingcai Niu.
11. In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution
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Alexandra Barbouti, Konstantinos Evangelou, Ioannis S. Pateras, Alexandra Papoudou-Bai, ... Vassilis G. Gorgoulis.
12. Oxidative stress-induced senescence markedly increases disc cell bioenergetics
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Tác giả
Prashanti Patil, Micol Falabella, Amal Saeed, Dayeong Lee, ... Nam V. Vo.
12. Modelling physical resilience in ageing mice
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Tác giả
Markus Schosserer, Gareth Banks, Soner Dogan, Peter Dungel, ... Ilaria Bellantuono.
13. Prioritized brain selenium retention and selenoprotein expression: Nutritional insights into Parkinson’s disease
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Tác giả
Xiong Zhang, Rong-Pei Liu, Wen-Hsing Cheng, Jian-Hong Zhu.
13. From bed to bench: How in silico medicine can help ageing research
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Marco Viceconti, Enrico Dall’Ara.
14. The ING1a model of rapid cell senescence
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Tác giả
Jessica Bertschmann, Subhash Thalappilly, Karl Riabowol.
15. Major traits of the senescent phenotype of nucleus pulposus intervertebral disc cells persist under the specific microenvironmental conditions of the tissue
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Tác giả
Anastasios Kouroumalis, Eleni Mavrogonatou, Olga D. Savvidou, Panayiotis J. Papagelopoulos, ... Dimitris Kletsas
16. Epigenetic and redox biomarkers: Novel insights from the MARK-AGE study
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Tác giả
Maria Moreno-Villanueva, Alexander Bürkle.
17. Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study
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Tác giả
M. Liset Rietman, Annemieke M.W. Spijkerman, Albert Wong, Harry van Steeg, ... Martijn E.T. Dollé.
18. Clinical and laboratory skin biomarkers of organ-specific diseases
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Tác giả
Christos C. Zouboulis, Eugenia Makrantonaki.
19. Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics
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Tác giả
Valérie Haydont, Bruno A. Bernard, Nicolas O. Fortunel.
20. Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility
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Tác giả
Valérie Haydont, Véronique Neiveyans, Hélène Zucchi, Nicolas O. Fortunel, Daniel Asselineau.
21. Immune signatures associated with mortality differ in elderly populations from different birth cohorts and countries even within northern Europe
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Tác giả
Immune signatures associated with mortality differ in elderly populations from different birth cohorts and countries even within northern Europe.
22. Regulation of metabolic health by essential dietary amino acids
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Tác giả
Cara L. Green, Dudley W. Lamming.
