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Investigational New Drugs
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Volume 37, October 2019, Issue 5, Pages 799-1116
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1. A novel humanized anti-PD-1 monoclonal antibody potentiates therapy in oral squamous cell carcinoma
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Tác giả
Y. Cai, Fei Wang, Q. Liu, Z. Li, D. Li, Z. Sun.
2. The bispecific anti-CD3 × anti-CD155 antibody mediates T cell immunotherapy for human prostate cancer
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Tác giả
Huijun Zhao, Juan Ma, Ting Lei, Wanru Ma, Man Zhang.
3. Lurbinectedin (PM01183), a selective inhibitor of active transcription, effectively eliminates both cancer cells and cancer stem cells in preclinical models of uterine cervical cancer
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Tác giả
Eriko Yokoi, Seiji Mabuchi, Kotaro Shimura, Naoko Komura.
4. The novel PI3K inhibitor S1 synergizes with sorafenib in non-small cell lung cancer cells involving the Akt-S6 signaling
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Tác giả
Juan Wang, Shumei Ma, Xiuhua Chen, Sanqi Zhang, Zhiyong Wang.
5. Caffeic acid phenethyl ester exerts apoptotic and oxidative stress on human multiple myeloma cells
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Tác giả
Elizabeth Hernandez Marin, Hana Paek, Mei Li, Yesung Ban.
6. The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines
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Tác giả
Malgorzata Kucinska, Helena Mieszczak.
7. A mediator of phosphorylated Smad2/3, evodiamine, in the reversion of TAF-induced EMT in normal colonic epithelial cells
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Tác giả
Wanbin Yang, Xiuli Gong, Xiulian Wang, Chao Huang.
8. A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer
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Tác giả
Weihua Hou, Qingyun Yuan, Xingxing Yuan, Yuxiong Wang, Wei Mo.
9. The availability of drug by liposomal drug delivery
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Tác giả
Evelien A. W. Smits, José A. Soetekouw, Ebel H. E. Pieters.
10. Modulator of the PI3K/Akt oncogenic pathway affects mTOR complex 2 in human adenocarcinoma cells
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Tác giả
Blair P. Curless, Nne E. Uko, Diane F. Matesic.
11. MICONIDINE acetate, a new selective and cytotoxic compound with synergic potential, induces cell cycle arrest and apoptosis in leukemia cells
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Tác giả
Mariana Franzoni Maioral, Natália Marceli Stefanes.
12. MiR-181a, a new regulator of TGF-β signaling, can promote cell migration and proliferation in gastric cancer
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Tác giả
Shaohua Ge, Haiyang Zhang, Ting Deng, Wu Sun, Tao Ning.
13. Screening, identification of prostate cancer urinary biomarkers and verification of important spots
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Tác giả
Huijun Zhao, Xuhong Zhao, Ting Lei, Man Zhang.
14. Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib
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Tác giả
Titto Augustine, Radhashree Maitra, Jinghang Zhang, Jay Nayak.
15. Biodistribution, pharmacokinetics and radioimmunotherapy of 188Re-cetuximab in NCI-H292 human lung tumor-bearing nude mice
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Tác giả
Ya-Jen Chang, Chung-Li Ho, Kai-Hung Cheng, Wan-I Kuo.
16. The rhenium(I)-diselenoether anticancer drug targets ROS, TGF-β1, VEGF-A, and IGF-1 in an in vitro experimental model of triple-negative breast cancers
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Tác giả
Philippe Collery, Vijay Veena, Adhikesavan Harikrishnan.
17. The cellular effects of novel triazine nitrogen mustards in glioblastoma LBC3, LN-18 and LN-229 cell lines
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Tác giả
Rafał Krętowski, Danuta Drozdowska, Beata Kolesińska.
18. In vitro and in vivo cytotoxic activity and human serum albumin interaction for a methoxy-styryl-thiosemicarbazone
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Tác giả
Otávio Augusto Chaves, Isabela S. de Castro.
19. Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma
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Tác giả
Yi Luo, Anqi Zeng, Aiping Fang, Linjiang Song, Chen Fan.
20. Lopinavir-NO, a nitric oxide-releasing HIV protease inhibitor, suppresses the growth of melanoma cells in vitro and in vivo
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Tác giả
Svetlana Paskas, Emanuela Mazzon, Maria Sofia Basile.
21. Modified ingenol semi-synthetic derivatives from Euphorbia tirucalli induce cytotoxicity on a large panel of human cancer cell lines
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Tác giả
Viviane A. O Silva, Marcela N. Rosa, Olga Martinho.
22. Bispecific anti-CD3 x anti-B7-H3 antibody mediates T cell cytotoxic ability to human melanoma in vitro and in vivo
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Tác giả
Juan Ma, Tengfei Shang, Pan Ma, Xin Sun, Jin Zhao, Ximing Sun.
23. The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model
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Tác giả
Narine Ghazaryan, Naira Movsisyan, Joana Catarina Macedo.
24. A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4-targeting antibody carrying auristatin E, in metastatic castration-resistant prostate cancer
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Tác giả
Deaglan McHugh, Mario Eisenberger, Elisabeth I. Heath.
25. A phase I study of ontuxizumab, a humanized monoclonal antibody targeting endosialin, in Japanese patients with solid tumors
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Tác giả
Toshihiko Doi, Takeshi Aramaki, Hirofumi Yasui, Kei Muro.
26. Chemotherapy in pregnancy: exploratory study of the effects of paclitaxel on the expression of placental drug transporters
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Tác giả
Paul Berveiller, Olivier Mir, Séverine A. Degrelle.
27. The drug lag and associated factors for orphan anticancer drugs in Japan compared to the United States
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Tác giả
Hiroki Nakayama, Naoki Matsumaru, Katsura Tsukamoto.
28. Significant differences on submission lag following regulation reform for registration of novel therapeutic drugs in Taiwan
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Tác giả
I-Chen Sun.
29. Human antigen R and drug resistance in tumors
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Tác giả
Fenghai Zhou, Fa Zhang, Chuan Zhou, Mengtian Liang.
