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Investigational New Drugs
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Volume 37, August 2019, Issue 4, Pages 595-797
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1. The Monocarboxylate transporter inhibitor Quercetin induces intracellular acidification in a mouse model of Glioblastoma Multiforme: in-vivo detection using magnetic resonance imaging
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Tác giả
Mohammed Albatany, Susan Meakin, Robert Bartha.
2. Hexane partition from Annona crassiflora Mart. promotes cytotoxity and apoptosis on human cervical cancer cell lines
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Tác giả
Viviane A. O. Silva, Ana Laura V. Alves, Marcela N. Rosa.
3. Preclinical assessment of histone deacetylase inhibitor quisinostat as a therapeutic agent against esophageal squamous cell carcinoma
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Tác giả
Lei Zhong, Shu Zhou, Rongsheng Tong, Jianyou Shi, Lan Bai.
4. CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia
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Tác giả
Muhammed H. Rahaman, Yingyi Yu, Longjin Zhong, Julian Adams.
5. E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases
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Tác giả
Hani M. Babiker, Sara A. Byron, William P. D. Hendricks.
6. Relationship between expression of XRCC1 and tumor proliferation, migration, invasion, and angiogenesis in glioma
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Tác giả
Peng-jin Mei, Jin Bai, Fa-an Miao, Zhong-lin Li, Chen Chen.
7. A phase I study of the vascular endothelial growth factor inhibitor Vatalanib in combination with Pemetrexed disodium in patients with advanced solid tumors
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Tác giả
Fen Wang, Julian Molina, Daniel Satele, Jun Yin, Vun-Sin Lim.
8. Mass balance, routes of excretion, and pharmacokinetics of investigational oral [14C]-alisertib (MLN8237), an Aurora A kinase inhibitor in patients with advanced solid tumors
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Tác giả
Xiaofei Zhou, Sandeepraj Pusalkar, Swapan K. Chowdhury.
9. First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors
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Tác giả
Elena Elez, Carlos Gomez-Roca, Arturo Soto Matos-Pita.
10. A phase I study of the safety and tolerability of VLX600, an Iron Chelator, in patients with refractory advanced solid tumors
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Tác giả
Kabir Mody, Aaron S. Mansfield, Lalitha Vemireddy.
11. Phase I dose-escalation study of F14512, a polyamine-vectorized topoisomerase II inhibitor, in patients with platinum-refractory or resistant ovarian cancer
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Tác giả
Alexandra Leary, Christophe Le Tourneau, Andrea Varga.
12. A phase 1 trial of Vorinostat in combination with concurrent chemoradiation therapy in the treatment of advanced staged head and neck squamous cell carcinoma
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Tác giả
Theodoros N. Teknos, J. Grecula, A. Agrawal, M. O. Old.
13. Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers
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Tác giả
Lisa Seitz, Lixia Jin, Manmohan Leleti, Devika Ashok.
14. A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors
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Tác giả
David C. Smith, Rashmi Chugh, Amita Patnaik.
15. Apatinib, a novel VEGFR inhibitor plus docetaxel in advanced lung adenocarcinoma patients with wild-type EGFR: a phase I trial
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Tác giả
Jian-Chun Duan, Zhi-Jie Wang, Lin Lin, Jun-Ling Li, Yan Wang.
16. A phase 2, open-label study of brentuximab vedotin in patients with CD30-expressing solid tumors
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Tác giả
Jeffrey P. Sharman, Jennifer J. Wheler, Lawrence Einhorn.
17. Phase II study of avelumab in multiple relapsed/refractory germ cell cancer
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Tác giả
M. Mego, D. Svetlovska, M. Chovanec, M. Rečkova, K. Rejlekova.
18. A phase II study of the orally administered negative enantiomer of gossypol (AT-101), a BH3 mimetic, in patients with advanced adrenal cortical carcinoma
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Tác giả
Hao Xie, Jun Yin, Manisha H. Shah, Michael E. Menefee.
19. Efficacy and safety of lanreotide in Korean patients with metastatic, well-differentiated gastroenteropancreatic-neuroendocrine tumors: a retrospective analysis
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Tác giả
Junho Kang, Changhoon Yoo, Hee-Sang Hwang, Seung-Mo Hong.
20. Cyclodextrin polymers decorated with RGD peptide as delivery systems for targeted anti-cancer chemotherapy
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Tác giả
Maurizio Viale, Rita Tosto, Valentina Giglio.
21. Inhibition of AKT signalling by benzoxazine derivative LTUR6 through the modulation of downstream kinases
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Tác giả
Rejitha Suraj, Jasim Al-Rawi, Christopher Bradley.
22. An orally antitumor chalcone hybrid inhibited HepG2 cells growth and migration as the tubulin binding agent
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Tác giả
Wang Yan, Chen Xiangyu, Li Ya, Wang Yu, Xu Feng.
23. Durable response to the ALK inhibitor alectinib in inflammatory myofibroblastic tumor of the head and neck with a novel SQSTM1–ALK fusion: a case report
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Tác giả
Kazunori Honda, Shigenori Kadowaki, Kyoko Kato, Nobuhiro Hanai.
24. Correction to: A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL
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Tác giả
Jung Jin Hwang, Yong Sook Kim, Taelim Kim, Mi Joung Kim.
25. Correction to: Phase Ib/II study of gemcitabine, nab-paclitaxel, and pembrolizumab in metastatic pancreatic adenocarcinoma
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Tác giả
Glen J. Weiss, Lisa Blaydorn, Julia Beck.
