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Investigational New Drugs
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Volume 37, April 2019, Issue 2, Pages 201-400
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1. Methionine gamma lyase from Clostridium sporogenes increases the anticancer effect of doxorubicin in A549 cells and human cancer xenografts
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Tác giả
V. S. Pokrovsky, N. Yu Anisimova, D. Zh Davydov.
2. Dual targeting of bromodomain-containing 4 by AZD5153 and BCL2 by AZD4320 against B-cell lymphomas concomitantly overexpressing c-MYC and BCL2
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Tác giả
Tomoko Takimoto-Shimomura, Taku Tsukamoto, Saori Maegawa.
3. Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells
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Tác giả
Viviane A. O. Silva, Marcela N. Rosa, Vera Miranda-Gonçalves.
4. Alteration of benzo(a)pyrene biotransformation by resveratrol in ApcMin/+ mouse model of colon carcinogenesis
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Tác giả
Ashley C. Huderson, P. V. Rekha Devi, Mohammad S. Niaz.
5. Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types
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Tác giả
Cijo George Vazhappilly, Ekram Saleh, Wafaa Ramadan.
6. The marine natural product Scalarin inhibits the receptor for advanced glycation end products (RAGE) and autophagy in the PANC-1 and MIA PaCa-2 pancreatic cancer cell lines
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Tác giả
Esther Amalia Guzmán, Tara Peterson Pitts, Maria Cristina Diaz.
7. Characterization and phase I study of CLR457, an orally bioavailable pan-class I PI3-kinase inhibitor
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Tác giả
James J. Harding, Todd M. Bauer, Daniel S. W. Tan.
8. A phase Ib study of BGJ398, a pan-FGFR kinase inhibitor in combination with imatinib in patients with advanced gastrointestinal stromal tumor
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Tác giả
Ciara M. Kelly, Alexander N. Shoushtari, Li-Xuan Qin.
9. Phase I study of S-1 plus paclitaxel combination therapy as a first-line treatment in elderly patients with advanced non-small cell lung cancer
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Tác giả
Yusuke Chihara, Koji Date, Yoshizumi Takemura, Nobuyo Tamiya.
10. A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma
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Tác giả
Tycel Phillips, Paul M. Barr, Steven I. Park, Kathryn Kolibaba.
11. A phase I study of the farnesyltransferase inhibitor Tipifarnib in combination with the epidermal growth factor tyrosine kinase inhibitor Erlotinib in patients with advanced solid tumors
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Tác giả
Khalid Jazieh, Julian Molina, Jacob Allred, Jun Yin, Joel Reid.
12. Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer
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Tác giả
Laura W. Goff, Nilofer S. Azad, Stacey Stein.
13. Pazopanib with low fat meal (PALM) in advanced renal cell carcinoma
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Tác giả
Melissa A. Reimers, Maryann M. Shango.
14. Phase I/II study evaluating the safety and clinical efficacy of temsirolimus and bevacizumab in patients with chemotherapy refractory metastatic castration-resistant prostate cancer
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Tác giả
Pedro C. Barata, Matthew Cooney, Prateek Mendiratta.
15. A phase II trial of gemcitabine, S-1 and LV combination (GSL) therapy in patients with advanced pancreatic cancer
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Tác giả
Kei Saito, Hiroyuki Isayama, Yousuke Nakai, Naminatsu Takahara.
16. Efficacy and safety of the combination of metformin, everolimus and exemestane in overweight and obese postmenopausal patients with metastatic, hormone receptor-positive, HER2-negative breast cancer: a phase II study
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Tác giả
Clinton Yam, Francisco J. Esteva, Miral M. Patel.
17. IMRT combined with S-1 concurrent chemoradiotherapy in locally advanced nasopharyngeal carcinoma: a prospective phase II study
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Tác giả
Tao Lv, Yujie Wang, Dan Ou, Peiyao Liu, Songbing Qin.
18. Sarcoid-like reaction mimicking disease progression in an ALK-positive lung cancer patient receiving lorlatinib
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Tác giả
Francesco Facchinetti, Letizia Gnetti, Valeria Balestra.
19. Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model
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Tác giả
Weijing Cai, Ranjala Ratnayake, Michael H. Gerber, Qi-Yin Chen.
20. Long-term adverse event: inflammatory orbitopathy induced by pembrolizumab in a patient with metastatic melanoma
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Tác giả
Charlée Nardin, Sophie Borot, Marie-Astride Beaudoin.
21. Novel N-1 substituted fluoroquinolones inhibit human topoisomerase I activity and exhibit anti-proliferative activity
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Tác giả
Lisa M. Oppegard, Justine L. Delgado, Chaitanya A. Kulkarni.
22. Identification of differentially expressed genes and signaling pathways using bioinformatics in interstitial lung disease due to tyrosine kinase inhibitors targeting the epidermal growth factor receptor
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Tác giả
Yuan Lu, Ang Li, Xiaofeng Lai, Jun Jiang, Lihong Zhang.
