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Investigational New Drugs
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Volume 37, February 2019, Issue 1, Pages 1-199
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1. Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate
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Catherine M. E. Barnett, Natasa Broit, Pei-Yi Yap.
2. Inhibiting IL-2 signaling and the regulatory T-cell pathway using computationally designed peptides
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Tác giả
Tammy Price-Troska, Zhi-Zhang Yang, David Diller.
3. Human acute myeloid leukemia cells express Neurokinin-1 receptor, which is involved in the antileukemic effect of Neurokinin-1 receptor antagonists
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Tác giả
A. Molinos-Quintana, P. Trujillo-Hacha, J. I. Piruat.
4. Copper-tolfenamic acid: evaluation of stability and anti-cancer activity
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Tác giả
Myrna Hurtado, Umesh T. Sankpal, Jaya Chhabra.
5. Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology – phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells
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Tác giả
Mateusz Psurski, Agnieszka Łupicka-Słowik.
6. Immuno-therapeutic potential of Schistosoma mansoni and Trichinella spiralis antigens in a murine model of colon cancer
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Tác giả
Maha M. Eissa, Cherine A. Ismail, Mervat Z. El-Azzouni.
7. Preclinical study of the antitumor effect of sphingosine-1-phosphate receptor 1 antibody (S1PR1-antibody) against human breast cancer cells
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Tác giả
Shujun Xiao, Jian Yang.
8. The poly (ADP-ribose) polymerase inhibitor rucaparib suppresses proliferation and serves as an effective radiosensitizer in cervical cancer
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Tác giả
Mei Tang, Qiuli Liu, Leyuan Zhou, Ling Chen, Xueqing Yang.
9. Two phase I, pharmacokinetic, and pharmacodynamic studies of DFP-10917, a novel nucleoside analog with 14-day and 7-day continuous infusion schedules
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Tác giả
Kamalesh Sankhala, Chris H. Takimoto, Alain C. Mita.
10. Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors
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A Craig Lockhart, Todd M. Bauer, Charu Aggarwal, Carrie B. Lee.
11. A phase Ib study of sonidegib (LDE225), an oral small molecule inhibitor of smoothened or Hedgehog pathway, in combination with docetaxel in triple negative advanced breast cancer patients: GEICAM/2012–12 (EDALINE) study
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Tác giả
Manuel Ruiz-Borrego, Begoña Jimenez, Silvia Antolín.
12. Phase I study of resminostat, an HDAC inhibitor, combined with S-1 in patients with pre-treated biliary tract or pancreatic cancer
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Masafumi Ikeda, Izumi Ohno, Hideki Ueno, Shuichi Mitsunaga.
13. A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma
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Masafumi Ikeda, Manabu Morimoto, Masaomi Tajimi, Koichi Inoue.
14. Phase Ib trial combining capecitabine, erlotinib and bevacizumab in pancreatic adenocarcinoma - REBECA trial
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Christian Dittrich, Robert Königsberg, Martina Mittlböck.
15. Absorption, metabolism, and excretion of the antiemetic rolapitant, a selective neurokinin-1 receptor antagonist, in healthy male subjects
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Zhi-Yi Zhang, Jing Wang, Vikram Kansra, Xiaodong Wang.
16. First-in-human study of the anti-HB-EGF antibody U3-1565 in subjects with advanced solid tumors
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Tác giả
Kathleen N. Moore, Johanna C. Bendell, Patricia M. LoRusso.
17. Phase 1 dose-escalation study of momelotinib, a Janus kinase 1/2 inhibitor, combined with gemcitabine and nab-paclitaxel in patients with previously untreated metastatic pancreatic ductal adenocarcinoma
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Tác giả
Kimmie Ng, Andrew Hendifar, Alexander Starodub, Jorge Chaves.
18. Global trends in the distribution of cancer types among patients in oncology phase I trials, 1991–2015
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Kota Itahashi, Toshio Shimizu, Takafumi Koyama, Shunsuke Kondo….
19. Advanced development of ErbB family-targeted therapies in osteosarcoma treatment
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Wei Wang, Hua-fu Zhao, Teng-fei Yao, Hao Gong.
20. Leptomeningeal recurrence after long-term alectinib therapy for non-small cell lung cancer harboring an EML4-ALK fusion protein
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Tác giả
Takahisa Kawamura, Haruyasu Murakami, Haruki Kobayashi.
21. Antitumor evaluation of novel phenothiazine derivatives that inhibit migration and tubulin polymerization against gastric cancer MGC-803 cells
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Tác giả
Nan Liu, Zhe Jin, Jing Zhang, Jianjun Jin.
22. Acknowledgement of Reviewers 2018
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