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Bioorganic Chemistry
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Volume 91, October 2019, Hidden issue
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1. Editorial Board
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2. Issue TOC
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3. Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors
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Galina F. Makhaeva, Natalia A. Elkina, Evgeny V. Shchegolkov, Natalia P. Boltneva, ... Rudy J. Richardson.
4. Chemo-sensitizing activity of natural cadinanes from Heterotheca inuloides in human uterine sarcoma cells and their in silico interaction with ABC transporters
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José Luis Rodríguez-Chávez, Carlos A. Méndez-Cuesta, Teresa Ramírez-Apan, Verónica Egas, ... Guillermo Delgado.
5. Bioactivatable reductive cleavage of azobenzene for controlling functional dumbbell oligodeoxynucleotides
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Tác giả
Huajun Lei, Mengwu Mo, Yujian He, Ya Wu, ... Li Wu.
6. An efficient method for the synthesis of novel derivatives 4-{5-[4-(4-amino-5-mercapto-4H-[1,2,4]triazol-3-yl)-phenyl]-3-trifluoromethyl-pyrazol-1-yl}-benzenesulfonamide and their anti-inflammatory potential
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Tác giả
Ghulam Mustafa, Andrea Angeli, Muhammad Zia-ur-Rehman, Nosheen Akbar, ... Claudiu T. Supuran.
7. Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of phthalimide-sulfonylurea hybrids as PPARγ and SUR agonists
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Tác giả
Mohamed Ayman El-Zahabi, Eman R. Elbendary, Faida H. Bamanie, Mohamed F. Radwan, ... Ibrahim H. Eissa.
8. Flavonols and 4-thioflavonols as potential acetylcholinesterase and butyrylcholinesterase inhibitors: Synthesis, structure-activity relationship and molecular docking studies
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Tác giả
Ehsan Ullah Mughal, Amina Sadiq, Jamshaid Ashraf, Muhammad Naveed Zafar, ... Chaudhary Omer Javed.
9. Anti-inflammatory and antiproliferative prenylated carbazole alkaloids from Clausena vestita
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Yan-Ping Liu, Shi Hu, Yun-Yao Liu, Ming-Ming Zhang, ... Yan-Hui Fu.
10. Optimization of a single HPLC-PDA method for quantifying Metformin, Gliclazide, Pioglitazone, Dapagliflozin, Empagliflozin, Saxagliptin, Linagliptin and Teneligliptin using central composite design
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Ravi Kant, Ramesh Babu Bodla, Garima Kapoor, Rubina Bhutani.
11. One-step immobilization and purification of genetic engineering CBD fusion EndoS on cellulose for antibodies Fc-glycan remodeling
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Kai Zhao, Feng Tang, Wei Shi, Haofei Hong, ... Zhimeng Wu.
12. Revealing synergistic mechanism of multiple components in Stauntonia brachyanthera Hand.-Mazz. for gout by virtual screening and system pharmacological approach
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Qiong-qiong Hua, Ying Liu, Cai-hong Liu, Li Liu, Da-li Meng.
13. Ureidobenzenesulfonamides as efficient inhibitors of carbonic anhydrase II
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Immo Serbian, Philipp Schwarzenberger, Anne Loesche, Sophie Hoenke, ... René Csuk.
14. Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells
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Kunal Nepali, Mei-Hsiang Lin, Min-Wu Chao, Sheng-Jhih Peng, ... Jing-Ping Liou.
15. Synthesis of new arylhydrazide bearing Schiff bases/thiazolidinone: α-Amylase, urease activities and their molecular docking studies
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Fazal Rahim, Muhammad Taha, Hayat Ullah, Abdul Wadood, ... Mohammed Gollapalli.
16. Phytoscreening of Vochysiaceae species: Molecular identification by HPLC-ESI-MS/MS and evaluating of their antioxidant activity and inhibitory potential against human α-amylase and protein glycation
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R.R. Franco, A.B. Justino, M.M. Martins, C.G. Silva, ... F.S. Espindola.
17. 2,5-Disubstituted thiadiazoles as potent β-glucuronidase inhibitors; Synthesis, in vitro and in silico studies
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Muhammad Taha, Noor Barak Almandil, Umer Rashid, Muhammad Ali, ... Khalid Mohammed Khan.
18. The 5-hydrazino-3-methylisothiazole-4-carboxylic acid, its new 5-substituted derivatives and their antiproliferative activity
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Izabela Jęśkowiak, Marcin Mączyński, Justyna Trynda, Joanna Wietrzyk, Stanisław Ryng.
19. Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands
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Katarzyna Szczepańska, Tadeusz Karcz, Agata Siwek, Kamil J. Kuder, ... Katarzyna Kieć-Kononowicz.
20. Utilization of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidinone as a cap moiety in design of novel histone deacetylase inhibitors
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Mamdouh F.A. Mohamed, Bahaa G.M. Youssif, Montaser Sh. A. Shaykoon, Mostafa H. Abdelrahman, ... Gamal El-Din A. Abuo-Rahma.
21. Synthesis, in-vitro α-glucosidase inhibition, antioxidant, in-vivo antidiabetic and molecular docking studies of pyrrolidine-2,5-dione and thiazolidine-2,4-dione derivatives
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Fida Hussain, Zeeshan Khan, Muhammad Saeed Jan, Sajjad Ahmad, ... Abdul Sadiq.
22. Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors
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Niccolò Chiaramonte, Silvia Bua, Andrea Angeli, Marta Ferraroni, ... Maria Novella Romanelli.
23. Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities
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Khaled R.A. Abdellatif, Wael A.A. Fadaly, Yaser A. Mostafa, Dana M. Zaher, Hany A. Omar.
24. Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties
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Fatoş Erdemir, Duygu Barut Celepci, Aydın Aktaş, Yetkin Gök, ... İlhami Gulçin.
25. Synthesis, physicochemical and biological evaluation of tacrine derivative labeled with technetium-99m and gallium-68 as a prospective diagnostic tool for early diagnosis of Alzheimer’s disease
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Ewa Gniazdowska, Przemysław Koźmiński, Paweł Halik, Marek Bajda, ... Paweł Szymański.
26. Design, synthesis and biological evaluation of trinary benzocoumarin-thiazoles-azomethines derivatives as effective and selective inhibitors of alkaline phosphatase
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Pervaiz Ali Channar, Hina Irum, Abid Mahmood, Ghulam Shabir, ... Jamshed Iqbal.
27. Designing of promising medicinal scaffolds for Alzheimer’s disease through enzyme inhibition, lead optimization, molecular docking and dynamic simulation approaches
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Mubashir Hassan, Muhammad Athar Abbasi, Aziz-ur-Rehman, Sabahat Zahra Siddiqui, ... Arif Malik.
28. Water soluble thioglycosylated BODIPYs for mitochondria targeted cytotoxicity
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Praseetha E. Kesavan, Vijayalakshmi Pandey, Md Kausar Raza, Shigeki Mori, Iti Gupta.
29. Tyrosol from marine Fungi, a novel Quorum sensing inhibitor against Chromobacterium violaceum and Pseudomonas aeruginosa
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Aiping Chang, Shiwei Sun, Li Li, Xiaoyun Dai, ... Hu Zhu.
30. Design, synthesis, biological and in silico evaluation of coumarin-hydrazone derivatives as tubulin targeted antiproliferative agents
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Pilli Govindaiah, Naresh Dumala, Irshad Mattan, Paramjit Grover, M. Jaya Prakash.
31. Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities
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Hae Min So, Jae Sik Yu, Zarha Khan, Lalita Subedi, ... Ki Hyun Kim.
32. Design, synthesis and biological evaluation of 4-aminoquinoline-guanylthiourea derivatives as antimalarial agents
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Shweta Bhagat, Minhajul Arfeen, Gourav Das, Mridula Ramkumar, ... Prasad V. Bharatam.
33. Arylboronate prodrugs of doxorubicin as promising chemotherapy for pancreatic cancer
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Charles Skarbek, Silvia Serra, Hichem Maslah, Estelle Rascol, Raphaël Labruère.
34. N-substituted noscapine derivatives as new antiprotozoal agents: Synthesis, antiparasitic activity and molecular docking study
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Kosar Babanezhad Harikandei, Peyman Salehi, Samad Nejad Ebrahimi, Morteza Bararjanian, ... Ahmed Al-Harrasi.
35. Mechanistic studies on Pyrobaculum calidifontis porphobilinogen synthase (5-aminolevulinic acid dehydratase)
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Naseema Azim, Qurratulann Afza Gardner, Naeem Rashid, Muhammad Akhtar.
36. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors
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Du-Chao Zhou, Yu-Ting Lu, Yan-Wen Mai, Chen Zhang, ... Zhi-Shu Huang.
37. A solid-phase method for synthesis of dimeric and trimeric ligands: Identification of potent bivalent ligands of 14-3-3σ
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Yeongju Lee, Brian Chung, Daseul Ko, Hyun-Suk Lim.
38. Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines
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Bilgesu Onur Sucu, Ozgecan Savlug Ipek, Sukran Ozdatli Kurtulus, Busra Emine Yazici, ... Mustafa Guzel.
39. Lysosome imaging in cancer cells by pyrene-benzothiazolium dyes: An alternative imaging approach for LAMP-1 expression based visualization methods to avoid background interference
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Chathura S. Abeywickrama, Kaveesha J. Wijesinghe, Robert V. Stahelin, Yi Pang.
40. Ugi efficient synthesis, biological evaluation and molecular docking of coumarin-quinoline hybrids as apoptotic agents through mitochondria-related pathways
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Salman Taheri, Maryam Nazifi, Mahboubeh Mansourian, Leila Hosseinzadeh, Yalda Shokoohinia.
41. Identification of novel peptidomimetics targeting the polo-box domain of polo-like kinase 1
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Zhiyan Li, Zhenguo Zhang, Huiyong Sun, Lili Xu, Cheng Jiang.
42. Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents
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Tác giả
Serdar Burmaoglu, Seyda Ozcan, Sevgi Balcioglu, Melis Gencel, ... Oztekin Algul.
43. Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives
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Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Derya Osmaniye, Serkan Levent, ... Zafer Asım Kaplancıklı.
44. Design, synthesis, anticancer evaluation and docking studies of new pyrimidine derivatives as potent thymidylate synthase inhibitors
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Lamia H.T. Amin, Taghreed Z. Shawer, Abeer M. El-Naggar, Hend M.A. El-Sehrawi.
45. Synthesis and biological evaluation of bergenin-1,2,3-triazole hybrids as novel class of anti-mitotic agents
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P. Pavan Kumar, Bandi Siva, Banoth Venkateswara Rao, G. Dileep Kumar, ... K. Suresh Babu.
46. Antifungal activity and tautomeric cyclization equilibria of formylphenylboronic acids
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Krzysztof M. Borys, Dorota Wieczorek, Kamila Pecura, Jacek Lipok, Agnieszka Adamczyk-Woźniak.
47. Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer’s disease therapy
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Rim Malek, Maciej Maj, Artur Wnorowski, Krzysztof Jóźwiak, ... Lhassane Ismaili.
48. Searching new structural scaffolds for BRAF inhibitors. An integrative study using theoretical and experimental techniques
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Ludmila E. Campos, Francisco M. Garibotto, Emilio Angelina, Jiri Kos, ... Ricardo D. Enriz.
49. Novel steroidal 1,3,4-thiadiazines: Synthesis and biological evaluation in androgen receptor-positive prostate cancer 22Rv1 cells
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Anna S. Komendantova, Alexander M. Scherbakov, Alexander V. Komkov, Viktoriya V. Chertkova, ... Igor V. Zavarzin.
50. Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM)
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Gangireddy Sujeevan Reddy, Ampalam Venkata Snehalatha, Rebecca Kristina Edwin, Kazi Amirul Hossain, ... Manojit Pal.
51. The novel economical synthesis and antimicrobial activity of a trithiocarbonate derivative
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Yahia N. Mabkhot, Jamal M.A. Khaled, Mujeeb A.S. Sultan, Naiyf S.H.A. Alharbi, ... H. Algarni.
52. Labeling of VEGFR1D2 through oxime ligation
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Lucia De Rosa, Rossella Di Stasi, Laura Longhitano, Luca Domenico D'Andrea.
53. New classes of carbazoles as potential multi-functional anti-Alzheimer’s agents
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Niloufar Choubdar, Mostafa Golshani, Leili Jalili-Baleh, Hamid Nadri, ... Mehdi Khoobi.
54. Iizukines C−E from a saline soil fungus Aspergillus iizukae
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Hui-Hui Kang, Mei-Jia Zhong, Li-Ying Ma, Xian-Guo Rong, ... Wei-Zhong Liu.
55. Strategy and validation of a structure-based method for the discovery of selective inhibitors of PAK isoforms and the evaluation of their anti-cancer activity
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Pei-Lu Song, Gang Wang, Yuan Su, Han-Xun Wang, ... Mao-Sheng Cheng.
56. Natural neuroprotective alkaloids from Stephania japonica (Thunb.) Miers
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Tác giả
Jiao Xiao, Tingyu Hao, Gang Chen, Junyu Song, ... Ning Li.
57. Tyrosine-based asymmetric urea ligand for prostate carcinoma: Tuning biological efficacy through in silico studies
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Sagnik Sengupta, Mena Asha Krishnan, Amit Pandit, Premansh Dudhe, ... Venkatesh Chelvam.
58. Synthesis and application of a “turn on” fluorescent probe for glutathione based on a copper complex of coumarin hydrazide Schiff base derivative
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Guangjie He, Xiaobo Hua, Nan Yang, Linlin Li, ... Liguo Ji.
59. New phenolic cinnamic acid derivatives as selective COX-2 inhibitors. Design, synthesis, biological activity and structure-activity relationships
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Daniela Ribeiro, Carina Poença, Carla Varela, João Janela, ... Fernanda M.F. Roleira.
60. Design, synthesis and evaluation of phthalazinone thiohydantoin-based derivative as potent PARP-1 inhibitors
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Yi Zhong, Ying Meng, Xi Xu, Lulu Zhao, ... Jinlei Bian.
61. Synthesis of novel (R)-4-fluorophenyl-1H-1,2,3-triazoles: A new class of α-glucosidase inhibitors
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Satya Kumar Avula, Ajmal Khan, Sobia Ahsan Halim, Zahra Al-Abri, ... Ahmed Al-Harrasi.
62. Synthesis, in silico and in vitro studies of new 1,4-dihydropiridine derivatives for antitumor and P-glycoprotein inhibitory activity
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Shirin Mollazadeh, Amirhossein Sahebkar, Fatemeh Kalalinia, Javad Behravan, Farzin Hadizadeh.
63. Bis-coumarins; non-cytotoxic selective urease inhibitors and antiglycation agents
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Uzma Salar, Arsalan Nizamani, Fizza Arshad, Khalid Mohammed Khan, ... M. Iqbal Choudhary.
64. cAMPS derivatives. A minireview over synthetic medicinal chemistry
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Kjell Undheim.
65. Discovery of Michael acceptor containing 1,4-dihydropyridines as first covalent inhibitors of L-/T-type calcium channels
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Hande Aygün Cevher, David Schaller, Maria A. Gandini, Ozan Kaplan, ... Miyase Gözde Gündüz.
66. A combined experimental and computational study on peptide nucleic acid (PNA) analogues of tumor suppressive miRNA-34a
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Valerio Piacenti, Emma Langella, Ida Autiero, John C. Nolan, ... Maria Moccia.
67. Discovery of novel cage-like heterocyclic hybrids as anti-inflammatory agents through the inhibition of nitrite, PGE2 and TNF-α
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Raju Suresh Kumar, Paulrayer Antonisamy, Abdulrahman I. Almansour, Natarajan Arumugam, ... Kang-Beom Kwon.
68. 1,8-Substituted anthraquinones, anthrones and bianthrones as potential non-azole leads against fungal infections
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Murhaf Jalab, Megan E. Critchley, Charlotte M. Taylor, Clare L. Lawrence, Robert B. Smith.
69. Three new cyclopiane-type diterpenes from a deep-sea derived fungus Penicillium sp. YPGA11 and their effects against human esophageal carcinoma cells
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Zhongbin Cheng, Yuanli Li, Wei Xu, Wan Liu, ... Qin Li.
70. New hexalactone derivatives and a pair of new oxaspiro-carbon epimeric glycosides from the fruits of Illicium lanceolatum
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Yang-Lan Liu, Xiao-Jing Wang, Ru-Bing Wang, Mi Li, ... Shuang-Gang Ma.
71. FtsZ inhibitors as a new genera of antibacterial agents
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Swayansiddha Tripathy, Susanta Kumar Sahu.
72. Small molecule HDAC inhibitors: Promising agents for breast cancer treatment
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Meiling Huang, Jian Zhang, Changjiao Yan, Xiaohui Li, ... Rui Ling.
73. The influence of cationic dendrimers on antibacterial activity of phage endolysin against P. aeruginosa cells
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Karol Ciepluch, Barbara Maciejewska, Katarzyna Gałczyńska, Dorota Kuc-Ciepluch, ... Michał Arabski.
74. Chalcone derivatives and their antibacterial activities: Current development
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Tác giả
Man Xu, Piye Wu, Fan Shen, Jiayou Ji, K.P. Rakesh.
75. Design, synthesis and antibacterial activity evaluation of moxifloxacin-amide-1,2,3-triazole-isatin hybrids
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Feng Gao, Lei Ye, Fangong Kong, Gang Huang, Jiaqi Xiao.
76. Anti-inflammatory spiroaxane and drimane sesquiterpenoids from Talaromyces minioluteus (Penicillium minioluteum)
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Chunmei Chen, Weiguang Sun, Xiaorui Liu, Mengsha Wei, ... Yonghui Zhang.
77. Genetic dereplication of Trichoderma hypoxylon reveals two novel polycyclic lactones
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Tác giả
Lin Chen, HongBo Wu, Huan Liu, Erwei Li, ... Wen-Bing Yin.
