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Bioorganic Chemistry
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Volume 88, July 2019, Hidden issue
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1. Editorial Board
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2. Issue TOC
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3. Introducing article numbering to Journal of Bioorganic Chemistry
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4. Targeting hepatocellular carcinoma: Synthesis of new pyrazole-based derivatives, biological evaluation, DNA binding, and molecular modeling studies
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Dina M. Omran, Mariam A. Ghaly, Shahenda M. El-Messery, Farid A. Badria, ... Ihsan A. Shehata.
5. Probing the high potency of pyrazolyl pyrimidinetriones and thioxopyrimidinediones as selective and efficient non-nucleotide inhibitors of recombinant human ectonucleotidases
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Hina Andleeb, Shahid Hameed, Syeda Abida Ejaz, Imtiaz Khan, ... Jamshed Iqbal.
6. Identification of novel imidazole flavonoids as potent and selective inhibitors of protein tyrosine phosphatase
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Ling Zhang, Yu Ge, Qing Ming Wang, Cheng-He Zhou.
7. Vieloplains A-G, seven new guaiane-type sesquiterpenoid dimers from Xylopia vielana
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Yangguo Xie, Xianglong Zhong, Yongzhen Xiao, Shenglan Zhu, ... Weidong Zhang.
8. Synthesis and anti-tumor activity of [1,4] dioxino [2,3-f] quinazoline derivatives as dual inhibitors of c-Met and VEGFR-2
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Dengshuai Wei, Haoru Fan, Kun Zheng, Xuemei Qin, ... Liming Hu.
9. Substituted 1,3-dioxoisoindoline-4-aminoquinolines coupled via amide linkers: Synthesis, antiplasmodial and cytotoxic evaluation
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Anu Rani, Jenny Legac, Philip J. Rosenthal, Vipan Kumar.
10. Synthesis, antitumor testing and molecular modeling study of some new 6-substituted amido, azo or thioureido-quinazolin-4(3H)-ones
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Mohamed A. Sabry, Heba A. Ewida, Ghada S. Hassan, Mariam A. Ghaly, Hussein I. El-Subbagh.
11. Glucosamine-6-phosphate synthase inhibiting C3-β-cholesterol tethered spiro heterocyclic conjugates: Synthesis and their insight of DFT and docking study
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Govindasami Periyasami, Subban Kamalraj, Ramanathan Padmanaban, Santhakumar Yeswanth Kumar, ... Ali Aldalbahi.
12. Facile one-pot synthesis, antiproliferative evaluation and structure-activity relationships of 3-amino-1H-indoles and 3-amino-1H-7-azaindoles
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Peng-Cheng Diao, Meng-Jin Hu, Hai-Kui Yang, Wen-Wei You, Pei-Liang Zhao.
13. Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines
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Ann Christin Reiersølmoen, Thomas Ihle Aarhus, Sarah Eckelt, Kristin Gabestad Nørsett, ... Bård Helge Hoff.
14. 6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity
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Yeong-Geun Lee, Hwan Lee, Jin Ah Ryuk, Joo Tae Hwang, ... Nam-In Baek.
15. Hydrazones as novel epigenetic modulators: Correlation between TET 1 protein inhibition activity and their iron(II) binding ability
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Milan Jakubek, Zdeněk Kejík, Robert Kaplánek, Veronika Antonyová, ... Vladimír Král.
16. Synthesis of some new C2 substituted dihydropyrimidines and their electrophysiological evaluation as L-/T-type calcium channel blockers
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Mohamed Teleb, Ola H. Rizk, Fang-Xiong Zhang, Frank R. Fronczek, ... Hesham Fahmy.
17. Virtual screening of active compounds from Artemisia argyi and potential targets against gastric ulcer based on Network pharmacology
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Yue Wang, Yi-wei Sun, Yu-meng Wang, Yan Ju, Da-li Meng.
18. In-silico design and synthesis of N9-substituted β-Carbolines as PLK-1 inhibitors and their in-vitro/in-vivo tumor suppressing evaluation
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Gomathi Priya Jeyapal, Rajendiran Krishnasamy, Carolyn K. Suzuki, Sundararajan Venkatesh, M.J.N. Chandrasekar.
19. Novel eugenol bearing oxypropanolamines: Synthesis, characterization, antibacterial, antidiabetic, and anticholinergic potentials
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Hayriye Genç Bilgiçli, Ali Kestane, Parham Taslimi, Oguz Karabay, ... İlhami Gulçin.
20. Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity
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Yıldız Uygun Cebeci, Hacer Bayrak, Yakup Şirin.
21. Synthesis and in vitro antitumor activity of novel acylspermidine derivative N-(4-aminobutyl)-N-(3-aminopropyl)-8-hydroxy-dodecanamide (AAHD) against HepG2 cells
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Abdulrahman L. Al-Malki, Syed Shoeb Razvi, Furkhan Ahmed Mohammed, Mazin A. Zamzami, ... Said S. Moselhy.
22. Design, synthesis, anticancer evaluation, molecular docking and cell cycle analysis of 3-methyl-4,7-dihydropyrazolo[1,5-a]pyrimidine derivatives as potent histone lysine demethylases (KDM) inhibitors and apoptosis inducers
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Nadia Hanafy Metwally, Mona Said Mohamed, Eman Ali Ragb.
23. Synthesis and molecular docking study of some 3,4-dihydrothieno[2,3-d]pyrimidine derivatives as potential antimicrobial agents
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Omaima G. Shaaban, Doaa A.E. Issa, Alaa A. El-Tombary, Shrouk M. Abd El Wahab, ... Ibrahim A. Abdelwahab.
24. Isolation, identification, and quantification of Pentylcurcumene from Geophila repens: A new class of cholinesterase inhibitor for Alzheimer’s disease
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Umesh Chandra Dash, Satish Kanhar, Anshuman Dixit, Jagnehswar Dandapat, Atish Kumar Sahoo.
25. Phenanthroimidazole derivatives act as potent inducer of autophagy by activating DNA damage pathway
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Hao Zhang, Yue Song, Li Li, Shuang-Yan Zhang, ... Xi-Cheng Wang.
26. Hypoglycemic activity and mechanism of the sulfated rhamnose polysaccharides chromium(III) complex in type 2 diabetic mice
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Han Ye, Zhaopeng Shen, Jiefen Cui, Yujie Zhu, ... Peng Wang.
27. Discovery and development of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as Bcl-2/Mcl-1 inhibitors
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Renshuai Liu, Lulu Liu, Xinying Yang, Hao Fang.
28. Synthesis and systemic toxicity assessment of quinine-triazole scaffold with antiprotozoal potency
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Adarsh Sahu, Ram Kishore Agrawal, RajKishor Pandey.
29. Design, synthesis and photoinduced DNA cleavage studies of [1,2,4]-triazolo[4,3-a]quinoxalin-4(5H)-ones
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Garima Sumran, Ranjana Aggarwal, Ashwani Mittal, Aviral Aggarwal, Amit Gupta.
30. α-bisabolol β-D-fucopyranoside as a potential modulator of β-amyloid peptide induced neurotoxicity: An in vitro & in silico study
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Mahalingam Jeyakumar, Sethuraman Sathya, Soniya Gandhi, Prabhakarrao Tharra, ... Kasi Pandima Devi.
31. Design, synthesis and molecular docking of new N-4-piperazinyl ciprofloxacin-triazole hybrids with potential antimicrobial activity
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Hamada H.H. Mohammed, El-Shimaa M.N. Abdelhafez, Samar H. Abbas, Gamal A.I. Moustafa, ... Gamal El-Din A. Abuo-Rahma.
32. Fluoro-benzimidazole derivatives to cure Alzheimer’s disease: In-silico studies, synthesis, structure-activity relationship and in vivo evaluation for β secretase enzyme inhibition
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Sayyad Ali, Muhammad Hassham Hassan Bin Asad, Soham Maity, Wahid Zada, ... Izhar Hussain.
33. Synthesis and biological evaluation of 3-functionalized 2-phenyl- and 2-alkylbenzo[b]furans as antiproliferative agents against human melanoma cell line
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Halina Kwiecień, Magdalena Perużyńska, Karolina Stachowicz, Katarzyna Piotrowska, ... Marek Droździk.
34. Synthesis of thymol-based pyrazolines: An effort to perceive novel potent-antimalarials
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Dushyant Singh Raghuvanshi, Narsingh Verma, Shiv Vardan Singh, Sonam Khare, ... Arvind Singh Negi.
35. Evaluation of thioamides, thiolactams and thioureas as hydrogen sulfide (H2S) donors for lowering blood pressure
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Ewelina Zaorska, Tomasz Hutsch, Marta Gawryś-Kopczyńska, Ryszard Ostaszewski, ... Dominik Koszelewski.
36. Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers
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Souad A. Elmetwally, Khaled F. Saied, Ibrahim H. Eissa, Eslam B. Elkaeed.
37. Synthesis and evaluation of redox-sensitive gonadotropin-releasing hormone receptor-targeting peptide conjugates
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Yuxuan Dai, Na Yue, Chunxia Liu, Xingguang Cai, ... Hai Qian.
38. Synthesis, antimicrobial, antioxidant, cytotoxic, antiurease and molecular docking studies of N-(3-trifluoromethyl)benzoyl-N′-aryl thiourea derivatives
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Aneela Maalik, Hina Rahim, Muhammad Saleem, Nighat Fatima, ... Amara Mumtaz.
39. Magmenthanes A-H: Eight new meroterpenoids from the bark of Magnolia officinalis var. Biloba
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Chuan Li, Chuang-Jun Li, Jie Ma, Ji-Wu Huang, ... Dong-Ming Zhang.
40. Highly selective carbamate-based butyrylcholinesterase inhibitors derived from a naturally occurring pyranoisoflavone
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Chuanhai Wu, Yan-bei Tu, Ziyuan Li, Yan-fang Li.
41. Design and synthesis of the novel oleanolic acid-cinnamic acid ester derivatives and glycyrrhetinic acid-cinnamic acid ester derivatives with cytotoxic properties
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Rui Wang, Wei Yang, Yiqing Fan, Wim Dehaen, ... Qiyong Huai.
42. Discovery of Baicalin as NDM-1 inhibitor: Virtual screening, biological evaluation and molecular simulation
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Cheng Shi, Jingxiao Bao, Ying Sun, Xinyue Kang, ... Heng Zheng.
43. Synthesis, characterization, anticancer evaluation and mechanisms of cytotoxic activity of novel 3-hydroxy-3-pyrrolin-2-ones bearing thenoyl fragment: DNA, BSA interactions and molecular docking study
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Nenad Joksimović, Jelena Petronijević, Nenad Janković, Dejan Baskić, ... Zorica Bugarčić.
44. Natural urease inhibitors from Aloe vera resin and Lycium shawii and their structural-activity relationship and molecular docking study
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Najeeb Ur Rehman, Ajmal Khan, Ahmed Al-Harrasi, Mohammed Khiat, ... Muhammad Riaz.
45. Exploration of N-alkyl-2-[(4-oxo-3-(4-sulfamoylphenyl)-3,4-dihydroquinazolin-2-yl)thio]acetamide derivatives as anticancer and radiosensitizing agents
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Aiten M. Soliman, Mostafa M. Ghorab.
46. Design, synthesis and molecular docking of 1,4-benzodioxane thiazolidinedione piperazine derivatives as FabH inhibitors
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Juan Sun, Wen He, Han-Yu Liu, Jie Qin, Chun-Lin Ye.
47. Excavating precursors from the traditional Chinese herb Polygala tenuifolia and Gastrodia elata: Synthesis, anticonvulsant activity evaluation of 3,4,5-trimethoxycinnamic acid (TMCA) ester derivatives
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Zefeng Zhao, Yajun Bai, Jing Xie, Xufei Chen, ... Xiaohui Zheng.
48. Synthesis, computational molecular docking analysis and effectiveness on tyrosinase inhibition of kojic acid derivatives
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Gülşah Karakaya, Aslı Türe, Ayşe Ercan, Selin Öncül, Mutlu Dilsiz Aytemir.
49. Multifunctional nanoparticles from albumin for stimuli-responsive efficient dual drug delivery
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Hamed Nosrati, Fatemeh Abhari, Jalil Charmi, Soodabeh Davaran, Hossein Danafar.
50. New perspective on the metabolism of AD-1 in vivo: Characterization of a series of dammarane-type derivatives with novel metabolic sites and anticancer mechanisms of active oleanane-type metabolites
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Meng Ding, Xude Wang, Yumeng Zhang, Weihui Yuan, ... Yuqing Zhao.
51. Evaluation of cytotoxic activity and genotoxicity of structurally well characterized potent cobalt(II) phen–based antitumor drug entities: An in vitro and in vivo approach
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Huzaifa Yasir Khan, Mohd Owais Ansari, G.G.H.A. Shadab, Sartaj Tabassum, Farukh Arjmand.
52. Selective cyclooxygenase inhibition and ulcerogenic liability of some newly prepared anti-inflammatory agents having thiazolo[4,5-d]pyrimidine scaffold
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Rania B. Bakr, Amira A. Ghoneim, Amany A. Azouz.
53. Synthesis and evaluation of Quinoline-3-carbonitrile derivatives as potential antibacterial agents
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Salman A. Khan, Abdullah M. Asiri, Hadi Mussa Basisi, Mohammad Asad, ... Mohmmad Younus Wani.
54. Click chemistry-assisted synthesis of novel aminonaphthoquinone-1,2,3-triazole hybrids and investigation of their cytotoxicity and cancer cell cycle alterations
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Maryam Gholampour, Sara Ranjbar, Najmeh Edraki, Maryam Mohabbati, ... Mehdi Khoshneviszadeh.
55. Structural modifications of 2,3-indolobetulinic acid: Design and synthesis of highly potent α-glucosidase inhibitors
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Elmira F. Khusnutdinova, Anastasiya V. Petrova, Ha Nguyen Thi Thu, Anh Le Thi Tu, ... Oxana B. Kazakova.
56. Synthesis and biological evaluation of flavone-8-acrylamide derivatives as potential multi-target-directed anti Alzheimer agents and investigation of binding mechanism with acetylcholinesterase
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Jeelan Basha Shaik, Daniel Pushparaju Yeggoni, Yelamanda Rao Kandrakonda, Mohan Penumala, ... Damu Gangaiah Amooru.
57. Identification of anti-inflammatory polyketides from the coral-derived fungus Penicillium sclerotiorin: In vitro approaches and molecular-modeling
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Zhaoming Liu, Pei Qiu, Hongju Liu, Jing Li, ... Zhigang She.
58. Novel 9-(2-(1-arylethylidene)hydrazinyl)acridine derivatives: Target Topoisomerase 1 and growth inhibition of HeLa cancer cells
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Md Rafi Haider, Kamal Ahmad, Nadeem Siddiqui, Zulphikar Ali, ... M. Shahar Yar.
59. Dipyridamole inhibits α-amylase/α-glucosidase at sub-micromolar concentrations; in-vitro, in-vivo and theoretical studies
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Sajjad Esmaeili, Sarwar Azizian, Bahareh Shahmoradi, Sajad Moradi, ... Reza Khodarahmi.
60. Design, synthesis and molecular modeling studies on novel moxifloxacin derivatives as potential antibacterial and antituberculosis agents
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Tác giả
Aslı Türe, Necla Kulabaş, Serap İpek Dingiş, Kaan Birgül, ... İlkay Küçükgüzel.
61. Synthesis and identification of quinoline derivatives as topoisomerase I inhibitors with potent antipsoriasis activity in an animal model
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Wen-Jin Zhang, Peng-Hui Li, Min-Cong Zhao, Yao-Hao Gu, ... Zhi-Yun Du.
62. Identification of 10-dehydrooxyglycyuralin E as a selective human estrogen receptor alpha partial agonist
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Nao Saito, Keiko Kawase, Naoya Yamashita, Yingzhan Tang, ... Kiyomitsu Nemoto.
63. Investigation of the interaction between salvianolic acid C and xanthine oxidase: Insights from experimental studies merging with molecular docking methods
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Hongjin Tang, Dongsheng Zhao.
64. Chiral β-lactam-based integrin ligands through Lipase-catalysed kinetic resolution and their enantioselective receptor response
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Giulia Martelli, Paola Galletti, Monica Baiula, Luca Calcinari, ... Daria Giacomini.
65. Synthesis of oxazolidinone from enantiomerically enriched allylic alcohols and determination of their molecular docking and biologic activities
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Ufuk Atmaca, Rüya Kaya, Halide Sedef Karaman, Murat Çelik, İlhami Gülçin.
66. Cisplatin: The first metal based anticancer drug
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Sumit Ghosh.
67. Nimesulide analogues: From anti-inflammatory to antitumor agents
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Mafalda Catarro, João L. Serrano, Susana S. Ramos, Samuel Silvestre, Paulo Almeida.
68. Current development of 5-nitrofuran-2-yl derivatives as antitubercular agents
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Tilal Elsaman, Malik Suliman Mohamed, Magdi A. Mohamed.
69. Naphthalimides in fluorescent imaging of tumor hypoxia – An up-to-date review
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Rashmi Kumari, Dhanya Sunil, Raghumani S. Ningthoujam.
70. Chemical constituents from Vietnamese mangrove Calophyllum inophyllum and their anti-inflammatory effects
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Nguyen Van Thanh, Hyun-Jae Jang, Le Ba Vinh, Kieu Thi Phuong Linh, ... Seo Young Yang.
71. An exhaustive compilation on chemistry of triazolopyrimidine: A journey through decades
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Pankaj Kumar Singh, Shalki Choudhary, Aanchal Kashyap, Himanshu Verma, ... Om Silakari.
72. Discovery of cycloneolignan enantiomers from Isatis indigotica Fortune with neuroprotective effects against MPP+-induced SH-SY5Y cell injury
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Yu-Fei Xi, Si-Fan Liu, Wei Hong, Xiao-Yu Song, ... Shao-Jiang Song.
73. Phytosynthesis of silver nanoparticles using Mangifera indica flower extract as bioreductant and their broad-spectrum antibacterial activity
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Tác giả
Fuad Ameen, P. Srinivasan, T. Selvankumar, S. Kamala-Kannan, ... M. Govarthanan.
