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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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1. Editorial Board
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2. Type 1 diabetes induces cognitive dysfunction in rats associated with alterations of the gut microbiome and metabolomes in serum and hippocampus
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Hongchang Gao, Qiaoying Jiang, Hui Ji, Jie Ning, ... Hong Zheng.
2. Publisher's note
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2. Protein arginine methyltranferase-1 induces ER stress and epithelial-mesenchymal transition in renal tubular epithelial cells and contributes to diabetic nephropathy
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Yin-Yin Chen, Xiao-Fei Peng, Guo-Yong Liu, Jin-Song Liu, ... Li-Yu He.
2. Cholesterol metabolism, pancreatic β-cell function and diabetes
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Carla Perego, Lorenzo Da Dalt, Angela Pirillo, Alessandra Galli, ... Giuseppe D. Norata.
2. Post-translational modifications in brain health and disease
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Sónia C. Correia, Cristina Carvalho, Susana Cardoso, Paula I. Moreira.
2. Genetics and Epigenetics in Aging and Longevity: Myths and Truths
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Jun Ren, Yingmei Zhang.
2. Corrigendum to “MLL3 enhances the transcription of PD-L1 and regulates anti-tumor immunity” [Biochim. Biophys. Acta, Mol. Basis Dis. 1865 (2) (Feb 1, 2019) 454–463]
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Wei Xiong, Huanghao Deng, Changkun Huang, Cong Zeng, ... Liang Zhu.
2. Preface - Animal models in liver disease
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Peter Fickert, Martin Wagner.
2. The power of metabolism — Linking energy supply and demand with cardiac contractile function
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Michael Schwarzer, Torsten Doenst, Christine Des Rosiers, Jan F.C. Glatz.
2. Prognostic molecular markers in pediatric liver disease – Are there any?
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Jon Nielsen, Vibeke Brix Christensen, Lise Borgwardt, Allan Rasmussen, ... Mette Skalshøi Kjær.
2. Cause or casualty: The role of mitochondrial DNA in aging and age-associated disease
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E. Sandra Chocron, Erin Munkácsy, Andrew M. Pickering.
2. Reviewer Acknowledgement
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3. G-MDSC-derived exosomes attenuate collagen-induced arthritis by impairing Th1 and Th17 cell responses
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Dongwei Zhu, Jie Tian, Xinyu Wu, Min Li, ... Shengjun Wang.
3. Heparan sulfate proteoglycans: The sweet side of development turns sour in mucopolysaccharidoses
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Valeria De Pasquale, Luigi Michele Pavone.
3. FMO3 and its metabolite TMAO contribute to the formation of gallstones
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Yaoyao Chen, Zhenkun Weng, Qian Liu, Wentao Shao, ... Zhaoyan Jiang.
3. Molecular and cellular bases of diabetes: Focus on type 2 diabetes mouse model-TallyHo
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Kavya Tamarai, Jasvinder Singh Bhatti, P. Hemachandra Reddy.
3. Functions and dysfunctions of nitric oxide in brain
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Pol Picón-Pagès, Joan Garcia-Buendia, Francisco J. Muñoz.
3. Genetic and epigenetic regulation of human aging and longevity
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Brian J. Morris, Bradley J. Willcox, Timothy A. Donlon.
3. Corrigendum to “Activation of bradykinin B2 receptor induced the inflammatory responses of cytosolic phospholipase A2 after the early traumatic brain injury.” [Biochem. Biophys. Acta Mol. Basis Dis. 1864/9 Pt B (2018) 2957–2971]
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Honglu Chao, Liang Fan, Lin Zhao, Yinlong Liu, ... Jing Ji.
3. Anatomy of rodent and human livers: What are the differences?
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Nutmethee Kruepunga, Theodorus B.M. Hakvoort, Jill P.J.M. Hikspoors, S. Eleonore Köhler, Wouter H. Lamers.
3. Impact of exercise training on cardiovascular disease and risk
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Volker Adams, Axel Linke.
3. Impact of advanced glycation end products (AGEs) signaling in coronary artery disease
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Marinos Kosmopoulos, Dimitrios Drekolias, Phaedon D. Zavras, Christina Piperi, Athanasios G. Papavassiliou.
3. Periodontitis and mechanisms of cardiometabolic risk: Novel insights and future perspectives
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Francisco Mesa, Antonio Magan-Fernandez, Giuseppa Castellino, Roberta Chianetta, ... Manfredi Rizzo.
3. Role of autophagy in inherited metabolic and endocrine myopathies
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Ying Tan, Yan Gong, Maolong Dong, Zhaohui Pei, Jun Ren.
4. Multi-omics studies in cellular models of methylmalonic acidemia and propionic acidemia reveal dysregulation of serine metabolism
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Arianna Franca Anzmann, Sneha Pinto, Veronica Busa, James Carlson, ... Hilary J. Vernon.
4. IDH2 deficiency impairs cutaneous wound healing via ROS-dependent apoptosis
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Sung Hwan Kim, Jeen-Woo Park.
4. Sulforaphane protects against ethanol-induced apoptosis in neural crest cells through restoring epithelial-mesenchymal transition by epigenetically modulating the expression of Snail1
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Yihong Li, Fuqiang Yuan, Ting Wu, Lanhai Lu, ... Shao-yu Chen.
4. Mitophagy and mitochondrial integrity in cardiac ischemia-reperfusion injury
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Mingjie Yang, Becky S. Linn, Yingmei Zhang, Jun Ren.
4. Post-translational histone modifications and their interaction with sex influence normal brain development and elaboration of neuropsychiatric disorders
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G. Singh, V. Singh, J.S. Schneider.
4. Conserved signaling pathways genetically associated with longevity across the species
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Abdul Haseeb Khan, Zhiwen Zou, Yang Xiang, Shenghan Chen, Xiao-Li Tian.
4. TRPC channels: Regulation, dysregulation and contributions to chronic kidney disease
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Stuart E. Dryer, Hila Roshanravan, Eun Young Kim.
4. Genetically modified mouse models to study hepatic neutral lipid mobilization
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Guenter Haemmerle, Achim Lass.
4. Dietary nitrate's effects on exercise performance in heart failure with reduced ejection fraction (HFrEF)
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Vinaya Mulkareddy, Susan B. Racette, Andrew R. Coggan, Linda R. Peterson.
4. Zebrafish disease models in hematology: Highlights on biological and translational impact
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Daniela Zizioli, Marina Mione, Marco Varinelli, Michele Malagola, ... Domenico Russo.
4. Acute pancreatic beta cell apoptosis by IL-1β is responsible for postburn hyperglycemia: Evidence from humans and mice
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Jun Li, Jie Xu, Xinghua Qin, Hongyan Yang, ... Feng Gao.
4. The role of obesity in inflammatory bowel disease
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Roxane Kreuter, Miriam Wankell, Golo Ahlenstiel, Lionel Hebbard.
5. Glycolysis dependent lactate formation in neutrophils: A metabolic link between NOX-dependent and independent NETosis
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Deepika Awasthi, Sheela Nagarkoti, Samreen Sadaf, Tulika Chandra, ... Madhu Dikshit.
5. Salubrinal enhances eIF2α phosphorylation and improves fertility in a mouse model of Classic Galactosemia
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B. Balakrishnan, A. Siddiqi, J. Mella, A. Lupo, ... K. Lai.
5. Exacerbated intestinal inflammation in P2Y6 deficient mice is associated with Th17 activation
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Mabrouka Salem, Mohammed-Amine El Azreq, Julie Pelletier, Bernard Robaye, ... Jean Sévigny.
5. A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene
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Lars R. Jensen, Lillian Garrett, Sabine M. Hölter, Birgit Rathkolb, ... Andreas W. Kuss.
5. The impact of histone post-translational modifications in neurodegenerative diseases
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Samantha N. Cobos, Seth A. Bennett, Mariana P. Torrente.
5. Genetic regulation of longevity and age-associated diseases through the methionine sulfoxide reductase system
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Derek B. Oien, Jackob Moskovitz.
5. Cartilage biomechanics: A key factor for osteoarthritis regenerative medicine
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D. Martínez-Moreno, G. Jiménez, P. Gálvez-Martín, G. Rus, J.A. Marchal.
5. Animal models to study bile acid metabolism
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Jianing Li, Paul A. Dawson.
5. Application of Magnetic Resonance Spectroscopy in metabolic research
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Tineke van de Weijer, Vera B. Schrauwen-Hinderling.
5. Hepatic mTOR-AKT2-Insig2 signaling pathway contributes to the improvement of hepatic steatosis after Roux-en-Y Gastric Bypass in mice
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Qinling Pan, Tingfeng Qin, Yuan Gao, Shaojian Li, ... Geyang Xu.
5. Effect of alcohol on the interleukin 6-mediated inflammatory response in a new mouse model of acute-on-chronic liver injury
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Ersin Karatayli, Rabea A. Hall, Susanne N. Weber, Steven Dooley, Frank Lammert.
5. Bile acids and glucocorticoid metabolism in health and disease
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Verena Theiler-Schwetz, Alex Zaufel, Hansjörg Schlager, Barbara Obermayer-Pietsch, ... Gernot Zollner.
6. Chronic inhibition of chemokine receptor CXCR2 attenuates cardiac remodeling and dysfunction in spontaneously hypertensive rats
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Yun-Long Zhang, Chi Geng, Jie Yang, Jiao Fang, ... Ying Liu.
6. Elimination of KLK5 inhibits early skin tumorigenesis by reducing epidermal proteolysis and reinforcing epidermal microstructure
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Georgios Pampalakis, Eleni Zingkou, Lucas Kaklamanis, Magda Spella, ... Georgia Sotiropoulou.
6. Peli1 induction impairs cardiac microvascular endothelium through Hsp90 dissociation from IRE1α
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Qianwen Zhao, Jie Yang, Hao Chen, Jiantao Li, ... Yuehua Li.
6. The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response
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A.M. Merlot, G.M. Porter, S. Sahni, E.G. Lim, ... D.R. Richardson.
6. The role of posttranslational modifications of α-synuclein and LRRK2 in Parkinson's disease: Potential contributions of environmental factors
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Edward Pajarillo, Asha Rizor, Jayden Lee, Michael Aschner, Eunsook Lee.
6. Roles of long noncoding RNAs in aging and aging complications
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Ling Jin, Qirui Song, Weili Zhang, Bin Geng, Jun Cai.
6. Lysosome motility and distribution: Relevance in health and disease
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Juan Esteban Oyarzún, Jonathan Lagos, Mary Carmen Vázquez, Cristian Valls, ... Silvana Zanlungo.
6. Outside the liver box: The gut microbiota as pivotal modulator of liver diseases
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Annika Wahlström.
6. A pilot study of exercise-induced changes in mitochondrial oxygen metabolism measured by a cellular oxygen metabolism monitor (PICOMET)
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Philipp Baumbach, Charles Neu, Steffen Derlien, Michael Bauer, ... Sina M. Coldewey.
6. Ligation of CD180 contributes to endotoxic shock by regulating the accumulation and immunosuppressive activity of myeloid-derived suppressor cells through STAT3
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Guanjun Dong, Xiaoying Yao, Fenglian Yan, Hui Zhang, ... Huabao Xiong.
6. Pharmacologic IL-6Rα inhibition in cholangiocarcinoma promotes cancer cell growth and survival
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Florian Kleinegger, Eva Hofer, Christina Wodlej, Nicole Golob-Schwarzl, ... Johannes Haybaeck.
6. mTOR inhibitor INK128 attenuates systemic lupus erythematosus by regulating inflammation-induced CD11b+Gr1+ cells
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Guoping Shi, Dan Li, Xiaojing Li, Jing Ren, ... Yayi Hou.
7. Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF-β and MAPK signaling pathways
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Wuliji Saiyin, Lili Li, Hua Zhang, Yongbo Lu, Chunlin Qin.
7. Vibrational spectroscopy-based quantification of liver steatosis
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E. Szafraniec, S. Tott, E. Kus, D. Augustynska, ... M. Baranska.
7. Directed elimination of senescent cells attenuates development of osteoarthritis by inhibition of c-IAP and XIAP
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Wang Peilin, Teng Songsong, Zhuang Chengyu, Cui Zhi, ... Yi Chengqing.
7. MICAL2 is expressed in cancer associated neo-angiogenic capillary endothelia and it is required for endothelial cell viability, motility and VEGF response
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Ivana Barravecchia, Sara Mariotti, Angela Pucci, Francesca Scebba, ... Debora Angeloni
7. Post-translational modifications of Parkinson's disease-related proteins: Phosphorylation, SUMOylation and Ubiquitination
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Stella C. Junqueira, Eduarda G.Z. Centeno, Kevin A. Wilkinson, Helena Cimarosti.
7. MicroRNA-216a promotes M1 macrophages polarization and atherosclerosis progression by activating telomerase via the Smad3/NF-κB pathway
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Shujun Yang, Jian Li, Yu Chen, Shuyuan Zhang, ... Weili Zhang.
7. Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”), a condition that significantly impairs the quality of life of many cancer survivors
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Xiaojia Ren, Diana Boriero, Luksana Chaiswing, Subbarao Bondada, ... D. Allan Butterfield.
7. Liver diseases in the dish: iPSC and organoids as a new approach to modeling liver diseases
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Romina Fiorotto, Mariangela Amenduni, Valeria Mariotti, Luca Fabris, ... Mario Strazzabosco.
7. The role of mitochondria in sepsis-induced cardiomyopathy
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Giacomo Stanzani, Michael R. Duchen, Mervyn Singer.
7. LYN, a key mediator in estrogen-dependent suppression of osteoclast differentiation, survival, and function
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Shubhangi Gavali, Manoj Kumar Gupta, Bhavna Daswani, Mohan R. Wani, ... M. Ikram Khatkhatay.
7. Neuronal ceroid lipofuscinosis related ER membrane protein CLN8 regulates PP2A activity and ceramide levels
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Babita Adhikari, Bhagya De Silva, Joshua A. Molina, Ashton Allen, ... Stella Y. Lee.
7. Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice
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Natalia Presa, Robin D. Clugston, Susanne Lingrell, Samuel E. Kelly, ... Jelske N. van der Veen.
8. mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation
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Koki Abe, Toshiyuki Yano, Masaya Tanno, Takayuki Miki, ... Tetsuji Miura.
8. Adenovirus 36 improves glycemic control and markers of Alzheimer's disease pathogenesis
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V. Hegde, M. Vijayan, S. Kumar, Md Akheruzzaman, ... P.H. Reddy.
8. The regulation of NDRG2 expression during ATLL development after HTLV-1 infection
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Tomonaga Ichikawa, Shingo Nakahata, Masahiro Fujii, Hidekatsu Iha, ... Kazuhiro Morishita
8. Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21
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Christine J. Pol, Nina M. Pollak, Michael J. Jurczak, Effimia Zacharia, ... Konstantinos Drosatos.
8. Acetylation as a major determinant to microtubule-dependent autophagy: Relevance to Alzheimer's and Parkinson disease pathology
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A.R. Esteves, A.M. Palma, R. Gomes, D. Santos, ... S.M. Cardoso.
8. Aldehyde dehydrogenase 2 deficiency promotes atherosclerotic plaque instability through accelerating mitochondrial ROS-mediated vascular smooth muscle cell senescence
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Hong Zhu, Zeng Wang, Zhen Dong, Cong Wang, ... Yingmei Zhang.
8. Excitotoxicity, neuroinflammation and oxidant stress as molecular bases of epileptogenesis and epilepsy-derived neurodegeneration: The role of vitamin E
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Patrizia Ambrogini, Pierangelo Torquato, Desirée Bartolini, Maria Cristina Albertini, ... Francesco Galli.
8. Animal models of NAFLD from the pathologist's point of view
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Helmut Denk, Peter M. Abuja, Kurt Zatloukal.
8. Sphingosine-1-phosphate promotes barrier-stabilizing effects in human microvascular endothelial cells via AMPK-dependent mechanisms
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Sophie Dennhardt, Karl R. Finke, Andrea Huwiler, Sina M. Coldewey.
8. Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway
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Yi-Ming Li, Jing Zhang, Lian-Jiu Su, John A. Kellum, Zhi-Yong Peng.
8. SCUBE1-enhanced bone morphogenetic protein signaling protects against renal ischemia-reperfusion injury
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Wei-Ju Liao, Heng Lin, Ching-Feng Cheng, Shuk-Man Ka, ... Ruey-Bing Yang.
8. Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism
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Maria Raffaella Greco, Emeline Bon, Rosa Rubino, Lorenzo Guerra, ... Rosa Angela Cardone.
9. Identification of novel TGF-β regulated genes with pro-migratory roles
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Tác giả
Qi Liu, Nicholas Borcherding, Peng Shao, Huojun Cao, ... Hank Heng Qi.
9. Structure-toxicity relationships of saturated and unsaturated free fatty acids for elucidating the lipotoxic effects in human EndoC-βH1 beta-cells
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T. Plötz, A.S. von Hanstein, B. Krümmel, A. Laporte, ... S. Lenzen.
9. Critical role of the endogenous renin-angiotensin system in maintaining self-renewal and regeneration potential of epidermal stem cells
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Xuan Liao, Jing Xiao, Sheng-Hong Li, Li-Ling Xiao, ... Hong-Wei Liu.
9. METTL14 is essential for β-cell survival and insulin secretion
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Tác giả
Jun Liu, Guanzheng Luo, Juan Sun, Lili Men, ... Decheng Ren.
9. Differences in structure and function between human and murine tau
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Félix Hernández, Raquel Cuadros, Ivanna Ollá, Carlos García, ... Jesús Avila.
9. eNOS S-nitrosylation mediated OxLDL-induced endothelial dysfunction via increasing the interaction of eNOS with β‑catenin
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Tác giả
Wan Wang, Dan Wang, Chuiyu Kong, Shuangyue Li, ... Yong Ji.
9. RhoC/ROCK2 promotes vasculogenic mimicry formation primarily through ERK/MMPs in hepatocellular carcinoma
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Tác giả
Ji-Gang Zhang, Dan-Dan Zhang, Ying Liu, Juan-Ni Hu, ... Gao-Lin Liu.
9. Animal models of NAFLD from a hepatologist's point of view
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Tác giả
Daniel Jahn, Stefan Kircher, Heike M. Hermanns, Andreas Geier.
9. Mitochondrial quality control in the cardiac system: An integrative view
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Virgilio J.J. Cadete, Goutham Vasam, Keir J. Menzies, Yan Burelle.
9. Sphk2−/− mice are protected from obesity and insulin resistance
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Tác giả
Shwetha Ravichandran, Brian S. Finlin, Philip A. Kern, Sabire Özcan.
9. The deficiency of macrophage erythropoietin signaling contributes to delayed acute inflammation resolution in diet-induced obese mice
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Tác giả
Bangwei Luo, Zhishang Wang, Zhiyuan Zhang, Zigang Shen, Zhiren Zhang.
9. Epigenetic upregulation and functional role of the mitochondrial aspartate/glutamate carrier isoform 1 in hepatocellular carcinoma
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Tác giả
Vittoria Infantino, Francesco Dituri, Paolo Convertini, Anna Santarsiero, ... Vito Iacobazzi.
10. Neutrophil gelatinase-associated lipocalin (NGAL) is localised to the primary cilium in renal tubular epithelial cells - A novel source of urinary biomarkers of renal injury
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Hilary Cassidy, Jennifer Slyne, Michael Higgins, Robert Radford, ... Craig Slattery.
10. Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways
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Tác giả
Jia Li, Yang Zhao, Paul Coleman, Jinbiao Chen, ... Jennifer R. Gamble.
10. The good side of inflammation: Staphylococcus aureus proteins SpA and Sbi contribute to proper abscess formation and wound healing during skin and soft tissue infections
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Tác giả
Cintia D. Gonzalez, Camila Ledo, Eliana Cela, Inés Stella, ... Marisa I. Gómez.
10. The db mutation improves memory in younger mice in a model of Alzheimer's disease
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Le Zhang, Sun-Ok Fernandez-Kim, Tina L. Beckett, Dana M. Niedowicz, ... Jeffrey N. Keller.
10. Phosphoproteomics of Alzheimer disease brain: Insights into altered brain protein regulation of critical neuronal functions and their contributions to subsequent cognitive loss
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Tác giả
D. Allan Butterfield.
10. Endothelial cell senescence in aging-related vascular dysfunction
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Tác giả
Guanghong Jia, Annayya R. Aroor, Cassie Jia, James R. Sowers.
10. Hypothalamic expression of the atypical chemokine receptor ACKR2 is involved in the systemic regulation of glucose tolerance
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Milena Fioravante, Bruna Bombassaro, Albina F. Ramalho, Rodrigo F. de Moura, ... Licio A. Velloso.
10. Animal models of cholestasis: An update on inflammatory cholangiopathies
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Valeria Mariotti, Massimiliano Cadamuro, Carlo Spirli, Romina Fiorotto, ... Luca Fabris.
10. Multiple recycling routes: Canonical vs. non-canonical mitophagy in the heart
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Tác giả
Alexandra Moyzis, Åsa B. Gustafsson.
10. SIRT1 activation by SRT1720 attenuates bone cancer pain via preventing Drp1-mediated mitochondrial fission
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Ming-Yue Li, Jie-Qiong Ding, Qiong Tang, Miao-Miao Hao, ... Hai-Li Zhu.
10. Asthma alleviates obesity in males through regulating metabolism and energy expenditure
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Xiaomin Song, Bolun Li, Haoran Wang, Xuan Zou, ... Jing Wang.
10. Nr5a1-Cre-mediated Tspo conditional knockout mice with low growth rate and prediabetes symptoms – A mouse model of stress diabetes
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Tác giả
Jinjiang Fan, Enrico Campioli, Vassilios Papadopoulos.
11. Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice
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Vik Meadows, Lindsey Kennedy, Laura Hargrove, Jennifer Demieville, ... Heather Francis.
11. Role of endothelin receptor type A on catecholamine regulation in the olfactory bulb of DOCA-salt hypertensive rats: Hemodynamic implications
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María J. Guil, Mercedes I. Schöller, Luis R. Cassinotti, Vinicia C. Biancardi, ... Marcelo S. Vatta.
11. The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver
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Tina Hörbelt, Birgit Knebel, Pia Fahlbusch, David Barbosa, ... Jorg Kotzka.
11. Lipopolysaccharide and interferon-γ team up to activate HIF-1α via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells
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Iván Parra-Izquierdo, Irene Castaños-Mollor, Javier López, Cristina Gómez, ... Carmen García-Rodríguez.
11. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry
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Tác giả
Andrea Renee Kelley, Stephan B.H. Bach, George Perry.
11. Vascular smooth muscle cell senescence and age-related diseases: State of the art
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Tác giả
Chen Chi, Dong-Jie Li, Yu-Jie Jiang, Jie Tong, ... Fu-Ming Shen.
11. Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling
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Tác giả
Justyna Róg, Aleksandra Oksiejuk, Maxime R.F. Gosselin, Wojciech Brutkowski, ... Krzysztof Zabłocki.
11. Animal models for cystic fibrosis liver disease (CFLD)
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Tác giả
Romina Fiorotto, Mariangela Amenduni, Valeria Mariotti, Massimiliano Cadamuro, ... Mario Strazzabosco.
11. The role of mitochondrial cardiolipin in heart function and its implication in cardiac disease
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Tác giả
Jan Dudek, Magnus Hartmann, Peter Rehling.
11. The stability and oncogenic function of LIN28A are regulated by USP28
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Tác giả
Saba Haq, Soumyadip Das, Dong-Ho Kim, Arun Pandian Chandrasekaran, ... Suresh Ramakrishna.
11. Cofactors revisited – Predicting the impact of flavoprotein-related diseases on a genome scale
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Agnieszka B. Wegrzyn, Sarah Stolle, Rienk A. Rienksma, Vítor A.P. Martins dos Santos, ... Maria Suarez-Diez.
11. Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells
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Tác giả
Cecilia Nigro, Alessia Leone, Michele Longo, Immacolata Prevenzano, ... Claudia Miele.
12. Inhibition of peripheral serotonin synthesis by LP533401 and disturbances in calciotropic hormones attenuated excessive osteoblastogenesis with simultaneous improvement of bone mineral status in 5/6 nephrectomized rats
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Tác giả
Dariusz Pawlak, Tomasz Domaniewski, Beata Sieklucka, Magdalena Jakuc, Krystyna Pawlak.
12. Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway
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Tác giả
Yunjian Liu, Hyeong Geug Kim, Edward Dong, Chuanpeng Dong, ... Xiaocheng Charlie Dong.
12. H+-dependent inorganic phosphate transporter in breast cancer cells: Possible functions in the tumor microenvironment
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Tác giả
Marco Antonio Lacerda-Abreu, Thais Russo-Abrahão, Daniela Cosentino-Gomes, Michelle Tanny Cunha Nascimento, ... José Roberto Meyer-Fernandes.
12. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies
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Tác giả
Tiffany S. Pinho, Sónia C. Correia, George Perry, António Francisco Ambrósio, Paula I. Moreira.
12. Combating cellular senescence by sirtuins: Implications for atherosclerosis
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Tác giả
Sai Ma, Li Fan, Feng Cao.
12. The nitrone spin trap 5,5‑dimethyl‑1‑pyrroline N‑oxide binds to toll-like receptor-2-TIR-BB-loop domain and dampens downstream inflammatory signaling
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Tác giả
Marcos D. Muñoz, Lucas J. Gutierrez, Sandrine Delignat, Jules Russick, ... Dario C. Ramirez.
12. Animal models of autoimmune hepatitis
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Tác giả
Urs Christen.
12. Is there an effect of ischemic conditioning on myocardial contractile function following acute myocardial ischemia/reperfusion injury?
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Tác giả
Leanda Stoian, Martina Krüger, Joachim Schmitt, Petra Kleinbongard.
12. Adenosine receptors as a new target for resveratrol-mediated glioprotection
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Tác giả
Larissa Daniele Bobermin, Ricardo Haack Amaral Roppa, André Quincozes-Santos.
12. Evidence of metabolic memory-induced neurodegeneration and the therapeutic effects of glucagon-like peptide-1 receptor agonists via Forkhead box class O
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Tác giả
Song Chen, Qian Tang, Ying Wang, Zheng Xu, ... Xiang-Dong Gao.
12. TLR4 triggered complex inflammation in human pancreatic islets
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Tác giả
Wei He, Osmond Rebello, Rocco Savino, Rosa Terracciano, ... Kathrin Maedler.
13. Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis
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Tác giả
Honit Piplani, Stefanie Marek-Iannucci, Jon Sin, Jean Hou, ... Stephen J. Pandol.
13. Knocking out lca5 in zebrafish causes cone-rod dystrophy due to impaired outer segment protein trafficking
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Tác giả
Zhen Qu, Tinsae Assefa Yimer, Shanglun Xie, Fulton Wong, ... Mugen Liu.
13. Blood-brain barrier dysfunction underlying Alzheimer's disease is induced by an SSAO/VAP-1-dependent cerebrovascular activation with enhanced Aβ deposition
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Tác giả
Montse Solé, María Esteban-Lopez, Biel Taltavull, Cristina Fábregas, ... Mercedes Unzeta.
13. Interplay between NAD+ and acetyl‑CoA metabolism in ischemia-induced mitochondrial pathophysiology
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Tác giả
Nina Klimova, Aaron Long, Susana Scafidi, Tibor Kristian.
13. As time flies by: Investigating cardiac aging in the short-lived Drosophila model
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Tác giả
Anna C. Blice-Baum, Maria Clara Guida, Paul S. Hartley, Peter D. Adams, ... Anthony Cammarato.
13. Tissue plasminogen activator and neuropathy open the blood-nerve barrier with upregulation of microRNA-155-5p in male rats
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Tác giả
Ann-Kristin Reinhold, Shaobing Yang, Jeremy Tsung-Chieh Chen, Liu Hu, ... Heike L. Rittner.
13. Animal models of cholangiocarcinoma
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Tác giả
Emilien Loeuillard, Samantha R. Fischbach, Gregory J. Gores, Sumera Rizvi.
13. Hypoxia-inducible factor 1 signalling, metabolism and its therapeutic potential in cardiovascular disease
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Tác giả
Maria da Luz Sousa Fialho, Amira H. Abd Jamil, George A. Stannard, Lisa C. Heather.
13. Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant
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Tác giả
Toni Giorgino, Davide Mattioni, Amal Hassan, Mario Milani, ... Matteo de Rosa.
13. Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling
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Tác giả
Taylor Richards, Kavindiya Modarage, Charlotte Dean, Aidan McCarthy-Boxer, ... Paraskevi Goggolidou.
13. Metabolomics of Ndufs4−/− skeletal muscle: Adaptive mechanisms converge at the ubiquinone-cycle
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Tác giả
Karin Terburgh, Zander Lindeque, Shayne Mason, Francois van der Westhuizen, Roan Louw.
14. The molecular tweezer CLR01 reduces aggregated, pathologic, and seeding-competent α-synuclein in experimental multiple system atrophy
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Tác giả
Marcos Herrera-Vaquero, Danielle Bouquio, Martin Kallab, Karl Biggs, ... Nadia Stefanova.
14. Maternal obesity impairs fetal mitochondriogenesis and brown adipose tissue development partially via upregulation of miR-204-5p
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Tác giả
Hanning Wang, Yanting Chen, Xueying Mao, Min Du.
14. Reduction in urinary oxalate excretion in mouse models of Primary Hyperoxaluria by RNA interference inhibition of liver lactate dehydrogenase activity
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Tác giả
Kyle D. Wood, Ross P. Holmes, David Erbe, Abigail Liebow, ... John Knight.
14. Post-translational modifications in MeHg-induced neurotoxicity
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Tác giả
Tao Ke, Filipe Marques Gonçalves, Cinara Ludvig Gonçalves, Alessandra Antunes dos Santos, ... Michael Aschner.
14. Identifying the molecular and cellular signature of cardiac dilation following myocardial infarction
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Tác giả
Merry L. Lindsey, Yonggang Ma, Elizabeth R. Flynn, Michael D. Winniford, ... Kristine Y. DeLeon-Pennell.
14. Deficiency of mouse mast cell protease 4 mitigates cardiac dysfunctions in mice after myocardium infarction
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Tác giả
Yunzhe Wang, Cong-Lin Liu, Wenqian Fang, Xian Zhang, ... Jinying Zhang.
14. Animal models for hepatocellular carcinoma
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Tác giả
Hui Emma Zhang, James M. Henderson, Mark D. Gorrell.
14. PPARα-independent effects of nitrate supplementation on skeletal muscle metabolism in hypoxia
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Tác giả
Katie A. O'Brien, James A. Horscroft, Jules Devaux, Ross T. Lindsay, ... Andrew J. Murray.
14. The HCM-causing Y235S cMyBPC mutation accelerates contractile function by altering C1 domain structure
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Tác giả
Chang Yoon Doh, Jiayang Li, Ranganath Mamidi, Julian E. Stelzer.
14. CXCR6 protects from inflammation and fibrosis in NEMOLPC-KO mice
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Tác giả
Anke Liepelt, Alexander Wehr, Marlene Kohlhepp, Jana C. Mossanen, ... Frank Tacke.
14. A FBN1 3′UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome
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Tác giả
Anna-Maria Siegert, Gerardo García Díaz-Barriga, Anna Esteve-Codina, Miquel Navas-Madroñal, ... Gustavo Egea.
15. Cross-talk between guanidinoacetate neurotoxicity, memory and possible neuroprotective role of creatine
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Tác giả
Eduardo Peil Marques, Fernanda Silva Ferreira, Tiago Marcon Santos, Caroline Acauan Prezzi, ... Angela T.S. Wyse.
15. Adseverin modulates morphology and invasive function of MCF7 cells
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Tác giả
J. Tanic, Y. Wang, W. Lee, N.M. Coelho, ... C.A. McCulloch.
15. COL1A1 C-propeptide mutations cause ER mislocalization of procollagen and impair C-terminal procollagen processing
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Tác giả
Aileen M. Barnes, Aarthi Ashok, Elena N. Makareeva, Marina Brusel, ... Joan C. Marini.
15. Mitochondrial regulation of cardiac aging
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Tác giả
Yuhan Wang, Yujing Li, Chuting He, Bo Gou, Moshi Song.
15. Deficiency of perforin and hCNT1, a novel inborn error of pyrimidine metabolism, associated with a rapidly developing lethal phenotype due to multi-organ failure
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Tác giả
Sandra Pérez-Torras, Aida Mata-Ventosa, Britt Drögemöller, Maja Tarailo-Graovac, ... André B.P. van Kuilenburg.
15. In vitro and in vivo translational models for rare liver diseases
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Tác giả
Sharie J. Haugabook, Marc Ferrer, Elizabeth A. Ottinger.
15. Alternative respiratory chain enzymes: Therapeutic potential and possible pitfalls
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Sina Saari, Geovana S. Garcia, Katharina Bremer, Marina M. Chioda, ... Howard T. Jacobs.
15. Hepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant mice
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Tác giả
Md. Wasim Khan, Medha Priyadarshini, Jose Cordoba-Chacon, Thomas C. Becker, Brian T. Layden.
15. Treg cells depletion is a mechanism that drives microvascular dysfunction in mice with established hypertension
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Tác giả
Eman Radwan, Vishal Mali, Samuel Haddox, Amira El-Noweihi, ... Khalid Matrougui.
15. SREBP-2 aggravates breast cancer associated osteolysis by promoting osteoclastogenesis and breast cancer metastasis
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Tác giả
Zhiwei Jie, Ziang Xie, Wenbin Xu, Xiangde Zhao, ... Shunwu Fan.
16. Characterization of the C584R variant in the mtDNA depletion syndrome gene FBXL4, reveals a novel role for FBXL4 as a regulator of mitochondrial fusion
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Tác giả
Rasha Sabouny, Rachel Wong, Laurie Lee-Glover, Steven C. Greenway, ... Timothy E. Shutt.
16. Global glycosphingolipid analysis in urine and plasma of female Fabry disease patients
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Tác giả
Wendy E. Heywood, Ivan Doykov, Justyna Spiewak, Jenny Hallqvist, ... Albina Nowak.
16. Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells
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Elham Fanaee-Danesh, Chaitanya Chakravarthi Gali, Jelena Tadic, Martina Zandl-Lang, ... Ute Panzenboeck.
16. Double knockout of Akt2 and AMPK predisposes cardiac aging without affecting lifespan: Role of autophagy and mitophagy
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Tác giả
Shuyi Wang, Machender R. Kandadi, Jun Ren.
16. The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion
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Tác giả
Rowan F. van Golen, Megan J. Reiniers, Gerben Marsman, Lindy K. Alles, ... Michal Heger.
16. Animal models of portal hypertension
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Tác giả
P. Königshofer, K. Brusilovskaya, P. Schwabl, T. Reiberger.
16. Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock
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Tác giả
Kumar Subramani, Xiaogang Chu, Marie Warren, Mariah Lee, ... Raghavan Raju.
16. Role of adiponectin as a modulator of testicular function during aging in mice
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Mayank Choubey, Ashutosh Ranjan, Puran S. Bora, Fatima Baltazar, ... Amitabh Krishna.
16. Deficiency of the mitochondrial sulfide regulator ETHE1 disturbs cell growth, glutathione level and causes proteome alterations outside mitochondria
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Tác giả
Navid Sahebekhtiari, Paula Fernandez-Guerra, Zahra Nochi, Jasper Carlsen, ... Johan Palmfeldt.
17. Tetrahydrobiopterin enhances mitochondrial biogenesis and cardiac contractility via stimulation of PGC1α signaling
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Tác giả
Hyoung Kyu Kim, Jouhyun Jeon, In-Sung Song, Hae Jin Heo, ... Jin Han.
17. Cardiomyocyte targeted overexpression of IGF1 during detraining restores compromised cardiac condition via mTORC2 mediated switching of PKCδ to PKCα
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Tác giả
Emeli Chatterjee, Ratul Datta Chaudhuri, Sagartirtha Sarkar.
17. CXCR7 contributes to the aggressive phenotype of cholangiocarcinoma cells
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Tác giả
Alessandra Gentilini, Alessandra Caligiuri, Chiara Raggi, Krista Rombouts, ... Fabio Marra.
17. Diabetic gut microbiota dysbiosis as an inflammaging and immunosenescence condition that fosters progression of retinopathy and nephropathy
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Tác giả
Rosa Fernandes, Sofia D. Viana, Sara Nunes, Flávio Reis.
17. Epstein–Barr virus noncoding RNAs from the extracellular vesicles of nasopharyngeal carcinoma (NPC) cells promote angiogenesis via TLR3/RIG-I-mediated VCAM-1 expression
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Tác giả
Shiyue Cheng, Zhi Li, Junju He, Shujun Fu, ... Lun-Quan Sun.
17. Animal models of drug-induced liver injury
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Tác giả
Mitchell R. McGill, Hartmut Jaeschke.
17. Fatty acids uptake and oxidation are increased in the liver of rats with adjuvant-induced arthritis
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Tác giả
Mariana M.N. Wendt, Monique Cristine de Oliveira, Gabriela B. Franco-Salla, Lorena Santos Castro, ... Jurandir F. Comar.
17. Mutations in glucokinase and other genes detected in neonatal and type 1B diabetes patient using whole exome sequencing may lead to disease-causing changes in protein activity
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Tác giả
Dao-Chen Lin, Chi-Yu Huang, Wei-Hsin Ting, Fu-Sung Lo, ... Yann-Jinn Lee.
17. Nod1-mediated lipolysis promotes diacylglycerol accumulation and successive inflammation via PKCδ-IRAK axis in adipocytes
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Tác giả
Aditya Sharma, Chandan K. Maurya, Deepti Arha, Amit K. Rai, ... Akhilesh K. Tamrakar.
18. Oleic acid increases the transcriptional activity of FoxO1 by promoting its nuclear translocation and β-catenin binding in pancreatic β-cells
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Tác giả
Magdalena Jazurek-Ciesiolka, Justyna Janikiewicz, Pawel Dobrzyn, Anna Dziewulska, ... Agnieszka Dobrzyn.
18. Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo
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Tác giả
Bartholomew P. Roland, Kristen R. Richards, Stacy L. Hrizo, Samantha Eicher, ... Michael J. Palladino.
18. Obesity is a common soil for premature cardiac aging and heart diseases - Role of autophagy
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Tác giả
Mingming Sun, Ying Tan, Maimaiti Rexiati, Maolong Dong, Wei Guo.
18. Glaucocalyxin A-induced oxidative stress inhibits the activation of STAT3 signaling pathway and suppresses osteosarcoma progression in vitro and in vivo
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Tác giả
Min Mao, Tao Zhang, Zhuoying Wang, Hongsheng Wang, ... Zhengdong Cai.
18. Down-regulated expression of LINC00518 prevents epithelial cell growth and metastasis in breast cancer through the inhibition of CDX2 methylation and the Wnt signaling pathway
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Tác giả
Hong-Bin Wang, Hong Wei, Jin-Song Wang, Lin Li, ... Zhi-Gao Li.
18. Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide
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Tác giả
Yunxiang Sun, Aleksandr Kakinen, Yanting Xing, Emily H. Pilkington, ... Feng Ding.
18. Paternal hyperglycemia induces transgenerational inheritance of susceptibility to hepatic steatosis in rats involving altered methylation on Pparα promoter
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Tác giả
Xinyu Li, Xiaoqin Shi, Yi Hou, Xuemei Cao, ... Xiaoqiu Xiao.
19. De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia
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Tác giả
Luis A. Cea, Elisa Balboa, Aníbal A. Vargas, Carlos Puebla, ... Juan C. Sáez.
19. Asparaginyl endopeptidase induces endothelial permeability and tumor metastasis via downregulating zonula occludens protein ZO-1
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Tác giả
Lichun Kang, Long Shen, Liqing Lu, Dekun Wang, ... Xiaoyue Tan.
19. Mst1 inhibits Sirt3 expression and contributes to diabetic cardiomyopathy through inhibiting Parkin-dependent mitophagy
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Tác giả
Shanjie Wang, Zhijing Zhao, Yanhong Fan, Mingming Zhang, ... Dongdong Sun.
19. Downregulated lncRNA-MIAT confers protection against erectile dysfunction by downregulating lipoprotein lipase via activation of miR-328a-5p in diabetic rats
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Tác giả
Wei Huo, Yi Hou, Yang Li, Hai Li.
19. Troglitazone activates TRPV1 and causes deacetylation of PPARγ in 3T3-L1 cells
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Tác giả
Vivek Krishnan, Padmamalini Baskaran, Baskaran Thyagarajan.
19. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice
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Tác giả
Chunling Yuan, Xiaoli Guo, Qifan Zhou, Fangyu Du, ... Libo Zou.
20. Liver disease predominates in a mouse model for mild human Zellweger spectrum disorder
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Tác giả
Kevin Berendse, Maxim Boek, Marion Gijbels, Nicole N. Van der Wel, ... Hans R. Waterham.
20. d-Ribose contributes to the glycation of serum protein
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Tác giả
Yao Chen, Lexiang Yu, Yujing Wang, Yan Wei, ... Rongqiao He.
20. Intracellular cholesterol stimulates ENaC by interacting with phosphatidylinositol‑4,5‑bisphosphate and mediates cyclosporine A-induced hypertension
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Tác giả
Yu-Jia Zhai, Ming-Ming Wu, Valerie A. Linck, Li Zou, ... He-Ping Ma.
20. Fibroblast growth factor 21 protects the heart from angiotensin II-induced cardiac hypertrophy and dysfunction via SIRT1
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Tác giả
Santie Li, Zhongxin Zhu, Mei Xue, Xinchu Yi, ... Litai Jin.
20. MLL3 enhances the transcription of PD-L1 and regulates anti-tumor immunity
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Tác giả
Wei Xiong, Huanghao Deng, Changkun Huang, Chong Zen, ... Liang Zhu.
20. KIF14 promotes tumor progression and metastasis and is an independent predictor of poor prognosis in human gastric cancer
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Tác giả
Zhongyin Yang, Chen Li, Chao Yan, Jianfang Li, ... Qinlong Gu.
21. Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: Protection by Melatonin
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Tác giả
Somanathapura K. NaveenKumar, Mahadevappa Hemshekhar, Kempaiah Kemparaju, Kesturu S. Girish.
21. Role of iron metabolism in heart failure: From iron deficiency to iron overload
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Tác giả
Hao Zhang, Pavel Zhabyeyev, Shaohua Wang, Gavin Y. Oudit.
21. Nrf2 deficiency aggravates Angiotensin II-induced cardiac injury by increasing hypertrophy and enhancing IL-6/STAT3-dependent inflammation
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Tác giả
Dandan Chen, Zhe Li, Peiqing Bao, Miao Chen, ... Junmei Ye.
21. Oxidized hemoglobin forms contribute to NLRP3 inflammasome-driven IL-1β production upon intravascular hemolysis
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Tác giả
Benard Bogonko Nyakundi, Andrea Tóth, Enikő Balogh, Béla Nagy, ... Viktória Jeney.
21. Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice
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Tác giả
Elisabeth Jeanclos, Monique Albersen, Rúben J.J. Ramos, Annette Raab, ... Antje Gohla.
22. Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria
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Tác giả
Ya-Long Feng, Hua Chen, Dan-Qian Chen, Nosratola D. Vaziri, ... Ying-Yong Zhao.
22. EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways
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Tác giả
Junghee Lee, Phuong T. Nguyen, Hyun Soo Shim, Seung Jae Hyeon, ... Hoon Ryu .
22. Genetic, structural, and functional analysis of pathogenic variations causing methylmalonyl-CoA epimerase deficiency
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Tác giả
Kathrin Heuberger, Henry J. Bailey, Patricie Burda, Apirat Chaikuad, ... Matthias R. Baumgartner.
22. Atrial natriuretic peptide attenuates endoplasmic reticulum stress in experimental acute pancreatitis
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Tác giả
Ana Paula Courreges, Ana Clara Najenson, Marcelo S. Vatta, Liliana G. Bianciotti.
22. Inhibition of CYP2E1 attenuates myocardial dysfunction in a murine model of insulin resistance through NLRP3-mediated regulation of mitophagy
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Tác giả
Jun Ren, Zhaohui Pei, Xiyao Chen, Melissa J. Berg, ... Yingmei Zhang.
23. IDH2 deficiency exacerbates acetaminophen hepatotoxicity in mice via mitochondrial dysfunction-induced apoptosis
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Tác giả
Hyunjin Kim, Jin Hyup Lee, Jeen-Woo Park.
23. Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish
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Tác giả
Shanglun Xie, Shanshan Han, Zhen Qu, Fei Liu, ... Mugen Liu.
23. Proteoglycan 4 deficiency protects against glucose intolerance and fatty liver disease in diet-induced obese mice
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Tác giả
Joya E. Nahon, Menno Hoekstra, Vanessa van Harmelen, Patrick C.N. Rensen, ... Miranda Van Eck.
23. Galectin-1 attenuates cardiomyocyte hypertrophy through splice-variant specific modulation of CaV1.2 calcium channel
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Tác giả
Jia Fan, Wenyong Fan, Jianzhen Lei, Yingying Zhou, ... Juejin Wang.
24. Impaired renal organic anion transport 1 (SLC22A6) and its regulation following acute myocardial infarction and reperfusion injury in rats
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Tác giả
Kungsadal Sirijariyawat, Atcharaporn Ontawong, Siripong Palee, Savitree Thummasorn, ... Chutima Srimaroeng.
24. Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression
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Tác giả
Sergio de Frutos, Alicia Luengo, Andrea García-Jérez, Marco Hatem-Vaquero, ... Laura Calleros.
24. RelA driven co-expression of CXCL13 and CXCR5 is governed by a multifaceted transcriptional program regulating breast cancer progression
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Tác giả
Subir Biswas, Sougata Roy Chowdhury, Gunjan Mandal, Suman Purohit, ... Arindam Bhattacharyya.
24. Early calcium handling imbalance in pressure overload-induced heart failure with nearly normal left ventricular ejection fraction
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Tác giả
Sarah Rouhana, Charlotte Farah, Jerome Roy, Amanda Finan, ... Nassim Fares.
25. Mutations of GADD45G in rabbits cause cleft lip by the disorder of proliferation, apoptosis and epithelial-mesenchymal transition (EMT)
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Tác giả
Yi Lu, Mingming Liang, Quanjun Zhang, Zhiquan Liu, ... Zhanjun Li.
25. Adipocyte MTERF4 regulates non-shivering adaptive thermogenesis and sympathetic-dependent glucose homeostasis
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Tác giả
Anna Castillo, Maria Vilà, Inés Pedriza, Rosario Pardo, ... Josep A. Villena.
25. Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic molecules
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Tác giả
Riyad A. Almaimani, Hussain Almasmoum, Mazen M. Ghaith, Mohamed El-Boshy, ... Bassem Refaat.
25. Protective role of soluble adenylyl cyclase against reperfusion-induced injury of cardiac cells
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Tác giả
Laura Rinaldi, Sofya Pozdniakova, Vignesh Jayarajan, Christian Troidl, ... Yury Ladilov.
26. CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy
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Tác giả
Lifang Yang, Shuyi Wang, Jipeng Ma, Ji Li, ... Jun Ren.
26. Wnt/β-catenin regulates blood pressure and kidney injury in rats
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Tác giả
Liangxiang Xiao, Bo Xu, Lili Zhou, Roderick J. Tan, ... Youhua Liu.
26. Corrigendum to “A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration” [Biochim. Biophys. Acta 1863 (2017) 801–809]
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Tác giả
Víctor López del Amo, Martina Palomino-Schätzlein, Marta Seco-Cervera, José Luis García-Giménez, ... Máximo Ibo Galindo.
27. 5-Lipoxagenase deficiency attenuates L-NAME-induced hypertension and vascular remodeling
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Tác giả
Jia-xiang Chen, Kun-yue Xue, Juan-juan Xin, Xin Yan, ... Wei Jiang.
27. Extent of rescue of F508del-CFTR function by VX-809 and VX-770 in human nasal epithelial cells correlates with SNP rs7512462 in SLC26A9 gene in F508del/F508del Cystic Fibrosis patients
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Tác giả
Arthur Kmit, Fernando Augusto Lima Marson, Stéphanie Villa-Nova Pereira, Adriana Mendes Vinagre, ... Margarida Duarte Amaral.
27. Corrigendum to “Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation” [Biochim. Biophys. Acta, 1862 (2016) 1182–1190]
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Tác giả
F. Bonacina, S.S. Barbieri, L. Cutuli, P. Amadi, ... G.D. Norata.
28. Argonaute-2 is associated to brown adipose tissue activation
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Tác giả
Estelle Roger, Olivier Dumortier, Didier F. Pisani, Nadine Gautier, ... Charlotte Hinault.
28. Lysophosphatidic acid receptor 1 inhibitor, AM095, attenuates diabetic nephropathy in mice by downregulation of TLR4/NF-κB signaling and NADPH oxidase
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Tác giả
Jong Han Lee, Mithun Kumer Sarker, Hojung Choi, Dongyun Shin, ... Hee-Sook Jun.
28. Corrigendum to “Interleukin-1β and tumor necrosis factor-α augment acidosis-induced rat articular chondrocyte apoptosis via nuclear factor-kappaB-dependent upregulation of ASIC1a channel” [Biochimica et Biophysica Acta 1864/1 (2018) 162–177]
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Tác giả
Ren-Peng Zhou, Bei-Bei Dai, Ya-Ya Xie, Xiao-Shan Wu, ... Fei-Hu Chen.
29. Activation of NFKB-JMJD3 signaling promotes bladder fibrosis via boosting bladder smooth muscle cell proliferation and collagen accumulation
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Tác giả
Junyu Lai, Manqing Ge, Sikui Shen, Lu Yang, ... Jianzhong Ai.
29. Treatment with celastrol protects against obesity through suppression of galanin-induced fat intake and activation of PGC-1α/GLUT4 axis-mediated glucose consumption
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Tác giả
Penghua Fang, Biao He, Mei Yu, Mingyi Shi, ... Ping Bo.
30. Human placental GLUT1 glucose transporter expression and the fetal insulin-like growth factor axis in pregnancies complicated by diabetes
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Tác giả
Marcus H. Borges, Janet Pullockaran, Patrick M. Catalano, Marc U. Baumann, ... Nicholas P. Illsley.
30. Impact of apolipoprotein A1- or lecithin:cholesterol acyltransferase-deficiency on white adipose tissue metabolic activity and glucose homeostasis in mice
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Tác giả
Eva Xepapadaki, Giuseppe Maulucci, Caterina Constantinou, Eleni A. Karavia, ... Kyriakos E. Kypreos.
31. l-Carnitine prevents oxidative stress in striatum of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload
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Tác giả
Gilian Guerreiro, Alexandre U. Amaral, Rafael Teixeira Ribeiro, Jéssica Faverzani, ... Carmen Regla Vargas.
31. Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1
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Tác giả
Sumit Sahni, Kyung Chan Park, Zaklina Kovacevic, Des R. Richardson.
32. Novel MicroRNA-455-3p and its protective effects against abnormal APP processing and amyloid beta toxicity in Alzheimer's disease
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Tác giả
Subodh Kumar, Arubala P. Reddy, Xiangling Yin, P. Hemachandra Reddy.
32. FMRpolyG alters mitochondrial transcripts level and respiratory chain complex assembly in Fragile X associated tremor/ataxia syndrome [FXTAS]
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Tác giả
Dhruv Gohel, Lakshmi Sripada, Paresh Prajapati, Kritarth Singh, ... Rajesh Singh.
33. The Smad3-miR-29b/miR-29c axis mediates the protective effect of macrophage migration inhibitory factor against cardiac fibrosis
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Tác giả
Jing-nan Liang, Xiao Zou, Xian-hong Fang, Jin-dong Xu, ... Zhi-xin Shan.
33. SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary
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Tác giả
Giovanna Di Emidio, Silvano Junior Santini, Anna Maria D'Alessandro, Antonella Vetuschi, ... Carla Tatone.
34. Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis
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Tác giả
Tho X. Pham, Minkyung Bae, Mi-Bo Kim, Yoojin Lee, ... Ji-Young Lee.
34. Inhibition of PRMT3 activity reduces hepatic steatosis without altering atherosclerosis susceptibility in apoE knockout mice
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Menno Hoekstra, Joya E. Nahon, Laura M. de Jong, Mara J. Kröner, ... Miranda Van Eck.
35. Human steroid sulfatase enhances aerobic glycolysis through induction of HIF1α and glycolytic enzymes
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Sangyun Shin, Yeo-Jung Kwon, Dong-Jin Ye, Hyoung-Seok Baek, ... Young-Jin Chun.
35. Sequence- and seed-structure-dependent polymorphic fibrils of alpha-synuclein
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Goki Tanaka, Tomoyuki Yamanaka, Yoshiaki Furukawa, Naoko Kajimura, ... Nobuyuki Nukina.
36. Warburg-like effect is a hallmark of complex I assembly defects
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Valerie Desquiret-Dumas, Geraldine Leman, Celine Wetterwald, Stephanie Chupin, ... Naig Gueguen.
36. Long non-coding RNA cytoskeleton regulator RNA (CYTOR) modulates pathological cardiac hypertrophy through miR-155-mediated IKKi signaling
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Yuan Yuan, Juan Wang, Qiuxiang Chen, Qingqing Wu, ... Difei Shen.
37. EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel-like factor 5 and β-catenin signaling
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Xuewu Sun, Hai Huang, Xin Pan, Shuoda Li, ... Peihua Shi.
37. Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability
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Zixing Fu, Fang Liu, Chunyue Liu, Beifang Jin, ... Xing Guo.
38. Apoptosis and cell proliferation in proximal tubular cells exposed to apoptotic bodies. Novel pathophysiological implications in cisplatin-induced renal injury
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Coral García-Pastor, Rafael Blázquez-Serra, Ricardo J. Bosch, Francisco J. Lucio Cazaña, Ana B. Fernández-Martínez.
38. Mitochondrial and calcium perturbations in rat CNS neurons induce calpain-cleavage of Parkin: Phosphatase inhibition stabilizes pSer65Parkin reducing its calpain-cleavage
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Hu Wang, Fanny Cheung, Anna C. Stoll, Patricia Rockwell, Maria E. Figueiredo-Pereira.
39. LncRNA GAS5 regulates vascular smooth muscle cell cycle arrest and apoptosis via p53 pathway
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Rui Tang, Xiaohan Mei, Yung-Chun Wang, Xiao-Bing Cui, ... Shi-You Chen.
39. Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice
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Hao Cheng, Tao Qi, Xiaojin Zhang, Qiuyue Kong, ... Zhengnian Ding.
40. Impact of hyperinsulinemia and hyperglycemia on valvular interstitial cells – A link between aortic heart valve degeneration and type 2 diabetes
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Jessica I. Selig, D. Margriet Ouwens, Silja Raschke, G. Hege Thoresen, ... Mareike Barth.
40. NLRX1 regulates TNF-α-induced mitochondria-lysosomal crosstalk to maintain the invasive and metastatic potential of breast cancer cells
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Kritarth Singh, Milton Roy, Paresh Prajapati, Anastasia Lipatova, ... Rajesh Singh.
41. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis
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Hayley Gallagher, Jessica O. Williams, Nele Ferekidis, Alaa Ismail, ... Dipak P. Ramji.
41. Inflammation-dependent ISG15 upregulation mediates MIA-induced dendrite damages and depression by disrupting NEDD4/Rap2A signaling
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Yu Hu, Xiao-Yue Hong, Xi-Fei Yang, Rong-Hong Ma, ... Gong-Ping Liu.
42. BRG1 regulates endothelial-derived IL-33 to promote ischemia-reperfusion induced renal injury and fibrosis in mice
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Li Liu, Lei Mao, Xiaoyan Wu, Teng Wu, ... Yong Xu.
42. Reduced biliverdin reductase-A levels are associated with early alterations of insulin signaling in obesity
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Flavia Agata Cimini, Andrea Arena, Ilaria Barchetta, Antonella Tramutola, ... Eugenio Barone.
43. Mutation in NADPH oxidase 3 (NOX3) impairs SHH signaling and increases cerebellar neural stem/progenitor cell proliferation
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P.C. Mazzonetto, C.B. Ariza, S.G. Ocanha, T.A. de Souza, ... M.A. Porcionatto.
44. Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation
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Bhanupriya Madarampalli, Gerald F.M. Watts, Paul M. Panipinto, Hung N. Nguygen, ... Erika H. Noss.
45. Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis
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Lixian Chen, Tianhao Zhou, Nan Wu, April O'Brien, ... Shannon Glaser.
46. GDF11 exhibits tumor suppressive properties in hepatocellular carcinoma cells by restricting clonal expansion and invasion
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Monserrat Gerardo-Ramírez, Roberto Lazzarini-Lechuga, Sharik Hernández-Rizo, Javier Esteban Jiménez-Salazar, ... Luis E. Gomez-Quiroz.
47. Chemokine (C-C motif) ligand 2 gene ablation protects low-density lipoprotein and paraoxonase-1 double deficient mice from liver injury, oxidative stress and inflammation
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Fedra Luciano-Mateo, Noemí Cabré, Salvador Fernández-Arroyo, Gerard Baiges-Gaya, ... Jorge Joven.
48. Intestinal vitamin D receptor modulates lipid metabolism, adipose tissue inflammation and liver steatosis in obese mice
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Daniel Jahn, Donata Dorbath, Anne-Kristin Schilling, Lisa Gildein, ... Andreas Geier.
49. Dystrobrevin is required postsynaptically for homeostatic potentiation at the Drosophila NMJ
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Salinee Jantrapirom, Wutigri Nimlamool, Piya Temviriyanukul, Somaieh Ahmadian, ... Saranyapin Potikanond.
50. PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles
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Alexander W. Fischer, Kirstin Albers, Christian Schlein, Frederike Sass, ... Joerg Heeren.
51. LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension
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Marius M. Zucker, Lukasz Wujak, Anna Gungl, Miroslava Didiasova, ... Malgorzata Wygrecka.
52. Mitochondrial fusion and maintenance of mitochondrial homeostasis in diabetic retinopathy
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Arul J. Duraisamy, Ghulam Mohammad, Renu A. Kowluru.
53. Mitochondrial ALDH2 protects against lipopolysaccharide-induced myocardial contractile dysfunction by suppression of ER stress and autophagy
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Jiaojiao Pang, Hu Peng, Shuyi Wang, Xihui Xu, ... Jun Ren.
54. Notch-1 decreased expression contributes to leptin receptor downregulation in nasal epithelium from allergic turbinates
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Andreina Bruno, Caterina Di Sano, Francesco Lorusso, Paola Dino, ... Elisabetta Pace.
55. Epigenetic silencing of genes enhanced by collective role of reactive oxygen species and MAPK signaling downstream ERK/Snail axis: Ectopic application of hydrogen peroxide repress CDH1 gene by enhanced DNA methyltransferase activity in human breast cancer
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Nibedita Pradhan, Sabnam Parbin, Swayamsiddha Kar, Laxmidhar Das, ... Samir Kumar Patra.
56. Novel cell line models to study mechanisms and overcoming strategies of proteasome inhibitor resistance in multiple myeloma
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Daniela Brünnert, Marianne Kraus, Thorsten Stühmer, Stefanie Kirner, ... Manik Chatterjee.
57. Reduction of SIRT1 blunts the protective effects of ischemic post-conditioning in diabetic mice by impairing the Akt signaling pathway
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Mingge Ding, Lang Hu, Hongyan Yang, Chao Gao, ... Yan Li.
58. Dietary cholesterol is essential to mast cell activation and associated obesity and diabetes in mice
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Xian Zhang, Qin Huang, Xin Wang, Zhiyong Deng, ... Guo-Ping Shi.
59. Metformin ameliorates endotoxemia-induced endothelial pro-inflammatory responses via AMPK-dependent mediation of HDAC5 and KLF2
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Rui Tian, Ranran Li, Yiyun Liu, Jialin Liu, ... Hongping Qu.
