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Drug Discovery Today
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Volume 24, Issue 9
Pages 1701-1954 (September 2019)
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1. Contents page 1
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Page i
2. Contents page 2
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Page ii
3. Can we use Nature’s Structure-Activity-Relationships to Make Better Drugs?
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Terry Kenakin.
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Pages 1701-1703
4. Standpoint on the priority of TNTs and CNTs as targeted drug delivery systems
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Tác giả
Yasmin Ranjous, Géza Regdon, Klára Pintye-Hódi, Tamás Sovány.
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Pages 1704-1709
5. 2018 in review: FDA approvals of new molecular entities
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Michael S. Kinch, Rebekah H. Griesenauer.
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Pages 1710-1714
6. Incorporating liquid biopsies into treatment decision-making: obstacles and possibilities
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Nick Beije, John W.M. Martens, Stefan Sleijfer.
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Pages 1715-1719
7. Impact of organ-on-a-chip technology on pharmaceutical R&D costs
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Nora Franzen, Wim H. van Harten, Valesca P. Retèl, Peter Loskill, ... Maarten IJzerman.
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Pages 1720-1724
8. Engineering microsystems to recapitulate brain physiology on a chip
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Kenneth Ndyabawe, William S. Kisaalita.
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Pages 1725-1730
9. Oxidative phosphorylation inducers fight pathological angiogenesis
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M.Pilar Bayona-Bafaluy, Olivia Esteban, Javier Ascaso, Julio Montoya, Eduardo Ruiz-Pesini.
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Pages 1731-1734
10. Unbiased data analytic strategies to improve biomarker discovery in precision medicine
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Saifur R. Khan, Yousef Manialawy, Michael B. Wheeler, Brian J. Cox.
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Pages 1735-1748
11. Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application
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Marta F. Simões, Rui M.A. Pinto, Sérgio Simões.
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Pages 1749-1768
12. The current status of pharmacotherapy for the treatment of Parkinson’s disease: transition from single-target to multitarget therapy
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Siew L. Cheong, Stephanie Federico, Giampiero Spalluto, Karl-Norbert Klotz, Giorgia Pastorin .
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Pages 1769-1783
13. Mini-gut: a promising model for drug development
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Yue-Bang Yin, Hugo R. de Jonge, Xin Wu, Yu-Long Yin.
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Pages 1784-1794
14. Data science tools and applications on the way to Pharma 4.0 Valentin
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Steinwandter, Daniel Borchert, Christoph Herwig.
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Pages 1795-1805
15. The human endogenous metabolome as a pharmacology baseline for drug discovery
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Andreu Bofill, Xavier Jalencas, Tudor I. Oprea, Jordi Mestres.
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Pages 1806-1820
16. The role of molecular simulations in understanding the mechanisms of cell-penetrating peptides
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Lauren M. Reid, Chandra S. Verma, Jonathan W. Essex.
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Pages 1821-1835
17. Cancer cell fusion: a potential target to tackle drug-resistant and metastatic cancer cells
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Clara Fernandes, Priyanka Prabhu, Kapil Juvale, Divya Suares, Mayur YC.
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Pages 1836-1844
18. Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
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Elaine D. Gonçalves, Rafael C. Dutra.
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Pages 1845-1853
19. Molecular modeling approaches for the discovery of adenosine A2B receptor antagonists: current status and future perspectives
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Pran Kishore Deb, Balakumar Chandrasekaran, Raghuprasad Mailavaram, Rakesh Kumar Tekade, Abdul Muttaleb Yousef Jaber.
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Pages 1854-1864
20. Physicians in the pharmaceutical industry: their roles, motivations, and perspectives
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Hussein Sweiti, Frank Wiegand, Christoph Bug, Martin Vogel.
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Pages 1865-1870
21. Correlates of time to approval and other clinical development periods
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Christopher D. Breder, Margaret VanHeusen, Lin-Chau Chang.
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Pages 1871-1876
22. Peptide-based protease inhibitors from plants
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Roland Hellinger, Christian W. Gruber.
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Pages 1877-1889
23. Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents
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Hon Liong Soo, Shun Ying Quah, Ibrahim Sulaiman, Sreenivasa Rao Sagineedu.
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Pages 1890-1898
24. Skin metabolism phase I and phase II enzymes in native and reconstructed human skin: a short review
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Siamaque Kazem, Emma Charlotte Linssen, Susan Gibbs.
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Pages 1899-1910
25. Antidepressants and nose-to-brain delivery: drivers, restraints, opportunities and challenges
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Carla Vitorino, Soraia Silva, Joana Bicker, Amílcar Falcão, Ana Fortuna.
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Pages 1911-1923
26. Future unmet medical need as a guiding principle for pharmaceutical R&D
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Matthias Vennemann, Vincent Ruland, Jan-Philip Kruse, Christine Harloff.
Nội dung
Pages 1924-1929
27. Toward a repositioning of the antibacterial drug nifuroxazide for cancer treatment
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Christian Bailly.
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Pages 1930-1936
28. Endothelin-1 traps as a potential therapeutic tool: from diabetes to beyond?
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Arjun Jain, Charles Coffey, Vidhi Mehrotra, Josef Flammer.
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Pages 1937-1942
29. Using molecular-mimicry-inducing pathways of pathogens as novel drug targets
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Anjali Garg, Bandana Kumari, Neelja Singhal, Manish Kumar.
Nội dung
Pages 1943-1952
30. Corrigendum to ‘Drug metabolism and pharmacokinetic strategies for oligonucleotide- and mRNA-based drug development’ Drug Discovery Today 23 (2018) 1733–1745
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Shalini Andersson, Madeleine Antonsson, Marie Elebring, Rasmus Jansson-Löfmark, Lars Weidolf.
Nội dung
Page 1953
