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Drug Discovery Today
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Volume 24, Issue 8
Pages 1425-1700 (August 2019)
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1. Contents page 1
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Nội dung
Page i
2. Contents page 2
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Nội dung
Page ii
3. Ocular drugs and drug delivery systems — Current trends and future perspectives
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Ilva D. Rupenthal, Ann L. Daugherty.
Nội dung
Pages 1425-1426
4. Emerging targets of inflammation and tear secretion in dry eye disease
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Maria Markoulli, Alex Hui.
Nội dung
Pages 1427-1432
5. The gap between the need for novel retinal drug delivery methods, technologies in R&D phase, and approved ocular drug delivery technologies
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Ron Neumann, Dana Barequet.
Nội dung
Pages 1433-1435
6. Potential antiedematous effects of intravitreous anti-VEGF, unrelated to VEGF neutralization
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Francine Behar-Cohen, Marilyn Dernigoghossian, Charlotte Andrieu-Soler, Rinath Levy.
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Pages 1436-1439
7. Protein conjugates and fusion proteins as ocular therapeutics
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Shrenik C. Mehta, Robert F. Kelley, Devin B. Tesar.
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Pages 1440-1445
8. Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties
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Astrid Subrizi, Eva M. del Amo, Viktor Korzhikov-Vlakh, Tatiana Tennikova.
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Pages 1446-1457
9. Depot formulations to sustain periocular drug delivery to the posterior eye segment
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Yosra Agban, Sachin S. Thakur, Odunayo O. Mugisho, Ilva D. Rupenthal.
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Pages 1458-1469
10. Hydrogels for sustained delivery of biologics to the back of the eye
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Debby Chang, Kinam Park, Amin Famili.
Nội dung
Pages 1470-1482
11. Müller cells as a target for retinal therapy
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Joke Devoldere, Karen Peynshaert, Stefaan C. De Smedt, Katrien Remaut.
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Pages 1483-1498
12. Recent advances in the management of diabetic retinopathy
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Nabeela Dulull, Faith Kwa, Narin Osman, Uma Rai.
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Pages 1499-1509
13. Intravitreal nanoparticles for retinal delivery
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Xiaonan Huang, Ying Chau.
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Pages 1510-1523
14. Therapeutic implications of nanomedicine for ocular drug delivery
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Tuo Meng, Vineet Kulkarni, Russell Simmers, Vikram Brar, Qingguo Xu.
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Pages 1524-1538
15. The safety evaluation of long-acting ocular delivery systems
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Evan A. Thackaberry, Florence Lorget, Cindy Farman, Vladimir Bantseev.
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Pages 1539-1550
16. Physiologically based ocular pharmacokinetic modeling using computational methods
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Paul J. Missel, Ramesh Sarangapani.
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Pages 1551-1563
17. Drug delivery systems and novel formulations to improve treatment of rare corneal disease
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Jorge Jimenez, Meera Sakthivel, Kanwal K. Nischal, Morgan V. Fedorchak.
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Pages 1564-1574
18. Poloxamer-based in situ gelling thermoresponsive systems for ocular drug delivery applications
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Karim A. Soliman, K Ullah, A. Shah, David S. Jones, Thakur R.R. Singh.
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Pages 1575-1586
19. Ocular biopharmaceutics: impact of modeling and simulation on topical ophthalmic formulation development
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Hovhannes J. Gukasyan, Shumet Hailu, Thomas K. Karami, Richard Graham.
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Pages 1587-1597
20. Targeting P2X7 receptors as a means for treating retinal disease
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Erica L. Fletcher, Anna Y. Wang, Andrew I. Jobling, Matthew V. Rutar.
Nội dung
Pages 1598-1605
21. Causative glaucoma treatment: promising targets and delivery systems
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Raphael Mietzner, Miriam Breunig.
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Pages 1606-1613
22. Nitric oxide: a drug target for glaucoma revisited
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Gerhard Garhöfer, Leopold Schmetterer.
Nội dung
Pages 1614-1620
23. Modified cells as potential ocular drug delivery systems
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Tatiana Tennikova, Arto Urtti.
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Pages 1621-1626
24. Connexin43 hemichannels: A potential drug target for the treatment of diabetic retinopathy
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Odunayo O. Mugisho, Colin R. Green, Jie Zhang, Monica L. Acosta, Ilva D. Rupenthal.
Nội dung
Pages 1627-1636
25. Drug delivery to retinal photoreceptors
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Erico Himawan, Per Ekström, Matej Buzgo, Pieter Gaillard.
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Pages 1637-1643
26. Combination therapy and co-delivery strategies to optimize treatment of posterior segment neurodegenerative diseases
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Alicia Arranz-Romera, Sergio Esteban-Pérez, David Garcia-Herranz, Alba Aragón-Navas.
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Pages 1644-1653
27. Targeting drug delivery within the suprachoroidal space
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Jae Hwan Jung, J. Jeremy Chae, Mark R. Prausnitz.
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Pages 1654-1659
28. Recent developments in liposomal drug delivery systems for the treatment of retinal diseases
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Andrew J. Urquhart, Anne Z. Eriksen.
Nội dung
Pages 1660-1668
29. Retinal cell regeneration using tissue engineered polymeric scaffolds
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Maria Abedin Zadeh, Mouhamad Khoder, Ali A. Al-Kinani, Husam M. Younes, Raid G. Alany.
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Pages 1669-1678
30. Challenges and opportunities for drug delivery to the posterior of the eye
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Fernando J. Cabrera, Daniel C. Wang, Kartik Reddy, Ghanashyam Acharya, Crystal S. Shin.
Nội dung
Pages 1679-1684
31. Ocular gene therapies in clinical practice: viral vectors and nonviral alternatives
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Thierry Bordet, Francine Behar-Cohen.
Nội dung
Pages 1685-1693
32. Recent advances in intraocular sustained-release drug delivery devices
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Tác giả
Yiqi Cao, Karen E. Samy, Daniel A. Bernards, Tejal A. Desai.
Nội dung
Pages 1694-1700
