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Drug Discovery Today
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Volume 24, Issue 2
Pages 361-664 (February 2019)
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1. Contents page 1
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Page i
2. Contents page 2
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Page ii
3. Toward improving drug delivery research in Egypt: Cancer Nanotechnology Research Laboratory (CNRL) as a role model
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Ahmed O. Elzoghby, May S. Freag.
Nội dung
Pages 361-363
4. Trends in interorganizational transactions in personalized medicine development
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Tomohiro Makino, Shintaro Sengoku, Shuichi Ishida, Kota Kodama.
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Pages 364-370
5. Impact of dosing schedule in animal experiments on compound progression decisions
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Chao Chen.
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Pages 371-376
6. Accelerating pharmaceutical structure-guided drug design: a successful model
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Lisa J. Keefe, Vincent S. Stoll.
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Pages 377-381
7. Lost medicines: a longer view of the pharmaceutical industry with the potential to reinvigorate discovery
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Michael S. Kinch, Grant A. Kinch, Rebekah H. Griesenauer.
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Pages 382-389
8. Evolution of commercially available compounds for HTS
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Dmitriy M. Volochnyuk, Sergey V. Ryabukhin, Yurii S. Moroz, Olena Savych.
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Pages 390-402
9. Interplay between hereditary and environmental factors to establish an in vitro disease model of keratoconus
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Subhadeep Roy, Saumya Yadav, Tanushree Dasgupta, Shikha Chawla.
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Pages 403-416
10. Gut reaction: impact of systemic diseases on gastrointestinal physiology and drug absorption
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Grace B. Hatton, Christine M. Madla, Sarit C. Rabbie, Abdul W. Basit.
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Pages 417-427
11. Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets
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Sven Günther, Paolo Fagone, Gaël Jalce, Atanas G. Atanasov.
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Pages 428-439
12. A review of non-invasive insulin delivery systems for diabetes therapy in clinical trials over the past decade
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Najma Easa, Raid G. Alany, Mark Carew, Anil Vangala.
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Pages 440-451
13. Meeting the discovery challenge of drug-resistant infections: progress and focusing resources
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Gordon Dougan, Chris Dowson, John Overington, Next Generation Antibiotic Discovery Symposium Participants.
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Pages 452-461
14. Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation
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Ghazal Nabil, Ketki Bhise, Samaresh Sau, Mohamed Atef.
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Pages 462-491
15. Accomplishments and challenges in stem cell imaging in vivo Rajendran J.C. Bose, Robert F. Mattrey
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Pages 492-504
16. The leukotriene signaling pathway: a druggable target in Alzheimer’s disease
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Johanna Michael, Julia Marschallinger, Ludwig Aigner.
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Pages 505-516
17. Towards the development of human immune-system-on-a-chip platforms
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Alessandro Polini, Loretta L. del Mercato, Adriano Barra, Yu Shrike Zhang.
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Pages 517-525
18. The power of combining phenotypic and target-focused drug discovery
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Ralf Heilker, Uta Lessel, Daniel Bischoff .
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Pages 526-532
19. Microtransplantation of human brain receptors into oocytes to tackle key questions in drug discovery
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Ruud Zwart, Francesca Mazzo, Emanuele Sher.
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Pages 533-543
20. The essentiality of drug targets: an analysis of current literature and genomic databases
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Xiao Ji, Deepak K. Rajpal, Johannes M. Freudenberg .
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Pages 544-550
21. Analysis of solvent-exposed and buried co-crystallized ligands: a case study to support the design of novel protein–protein interaction inhibitors
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Daniela Trisciuzzi, Orazio Nicolotti, Maria A. Miteva, Bruno O. Villoutreix.
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Pages 551-559
22. The future R&D landscape in non-alcoholic steatohepatitis (NASH)
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Darcey Black, Sarah Brockbank, Simon Cruwys, Kim Goldenstein.
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Pages 560-566
23. Application of nanotechnology to improve the therapeutic benefits of statins
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Shahla Korani, Mitra Korani, Samira Bahrami, Thomas P. Johnston.
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Pages 567-574
24. Advances in particle shape engineering for improved drug delivery
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Yiwei Yang, Di Nie, Yuan Liu, Miaorong Yu, Yong Gan.
Nội dung
Pages 575-583
25. Growing synergy of nanodiamonds in neurodegenerative interventions
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Jackson Saraf, Kiran Kalia, Pallab Bhattacharya, Rakesh Kumar Tekade.
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Pages 584-594
26. Strategies for brain-targeting liposomal delivery of small hydrophobic molecules in the treatment of neurodegenerative diseases
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Zi-Ying Wang, Sravan Gopalkrishnashetty Sreenivasmurthy, Ju-Xian Song, Jing-Yi Liu, Min Li.
Nội dung
Pages 595-605
27. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems
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Samuel T. Wilkinson, Gerard Sanacora.
Nội dung
Pages 606-615
28. Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer’s disease
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Jangampalli Adi Pradeepkiran, Arubala P. Reddy, P. Hemachandra Reddy.
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Pages 616-623
29. Advancing nonclinical innovation and safety in pharmaceutical testing
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Elizabeth J. Baker, Nancy A. Beck, Ellen L. Berg, Helene D. Clayton-Jeter.
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Pages 624-628
30. Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors
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Lanlan Jing, Gaochan Wu, Dongwei Kang, Zhongxia Zhou.
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Pages 629-635
31. Recent advances in pharmaceutical dosage forms and devices using additive manufacturing technologies
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Christos I. Gioumouxouzis, Christina Karavasili, Dimitrios G. Fatouros.
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Pages 636-643
32. Essential oils: from prevention to treatment of skin cancer
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P.S. Pavithra, Alka Mehta, Rama S. Verma.
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Pages 644-655
33. Targeting VEGF–neuropilin interactions: a promising antitumor strategy
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Kewen Peng, Ying Bai, Qihua Zhu, Bin Hu, Yungen Xu.
Nội dung
Pages 656-664
