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Experimental Hematology
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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Page IFC
1. Cover 2: Editorial Board
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1. Cover 2: Editorial Boar
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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1. Cover 2: Editorial Board
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2. Metcalf Lecture Award: Applying niche biology to engineer T-cell regenerative therapies
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David T. Scadden.
2. In Memoriam: A Tribute to Esmail Zanjani, 1938–2019
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João Ascensão, Chris Porada, Graça Almeida-Porada, Phil McGlave, Ron Hoffman.
2. Daily light and darkness onset and circadian rhythms metabolically synchronize hematopoietic stem cell differentiation and maintenance: The role of bone marrow norepinephrine, tumor necrosis factor, and melatonin cycles
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Karin Golan, Orit Kollet, Regina P. Markus, Tsvee Lapidot.
2. Biological implications of clonal hematopoiesis
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Tiago C. Luis, Adam C. Wilkinson, Isabel Beerman, Siddhartha Jaiswal, Liran I. Shlush.
2. Expanded potential stem cell media as a tool to study human developmental hematopoiesis in vitro
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Adam C. Wilkinson, David J. Ryan, Iwo Kucinski, Wei Wang, Berthold Gottgens.
2. Are transplantable stem cells required for adult hematopoiesis?
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Helen M. McRae, Anne K. Voss, Tim Thomas.
2. Pediatric leukemia: Moving toward more accurate models
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Thomas Milan, Hera Canaj, Chloe Villeneuve, Aditi Ghosh, Brian T. Wilhelm.
2. Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells
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Kacey L. Guenther, Patali S. Cheruku, Ayla Cash, Richard H. Smith, Andre Larochelle.
2. USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B-cell-mediated immune response in a mouse model
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Yun Hsiao Lin, Michael Forster, Yue Liang, Mansen Yu, Anastasia Nijnik.
2. Introduction
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Gay M. Crooks, Connie Eaves.
2. The case for plerixafor to replace filgrastim as the optimal agent to mobilize peripheral blood donors for allogeneic hematopoietic cell transplantation
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Stephen Couban, Peggy C. Wong, Kirk R. Schultz.
2. A rare subgroup of leukemia stem cells harbors relapse-inducing potential in acute lymphoblastic leukemia
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Daniela Senft, Irmela Jeremias.
3. Small-molecule nicotinamide for ex vivo expansion of umbilical cord blood
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Prioty Islam, Mitchell E. Horwitz.
3. KRasG12D expression in the bone marrow vascular niche affects hematopoiesis with inflammatory signals
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Cindy L. Hochstetler, Yuxin Feng, Mehmet Sacma, Ashley K. Davis, Yi Zheng.
3. Machine learning predicts putative hematopoietic stem cells within large single-cell transcriptomics data sets
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Fiona K. Hamey, Berthold Göttgens.
3. Auer rod-like inclusions in the cytoplasm of B-cell lymphoma cells with bone marrow infiltration
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Zhanxi Gao, Fang Cui, Mei Liu, Yukai Guo, Min Shi.
3. Lineage marker expression on mouse hematopoietic stem cells
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Jinhong Wang, Zixian Liu, Shanshan Zhang, Xiaofang Wang, Hideo Ema.
3. Translational regulation and deregulation in erythropoiesis
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Alexandra Vatikioti, Elena Karkoulia, Marina Ioannou, John Strouboulis.
3. Intracellular cytarabine triphosphate in circulating blasts post-treatment predicts remission status in patients with acute myeloid leukemia
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Elizabeth Anderson, Barbara Rees, Jonathon Hull, Jonathan Heywood, Priyanka Mehta.
3. Activin A contributes to the definition of a pro-oncogenic bone marrow microenvironment in t(12;21) preleukemia
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Federica Portale, Linda Beneforti, Alessandra Fallati, Andrea Biondi, Giovanna D'Amico.
3. DNA damage response-related alterations define the genetic background of patients with chronic lymphocytic leukemia and chromosomal gains
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María Hernández-Sánchez, Ana Eugenia Rodríguez-Vicente, Isabel González-Gascón y Marín, Miguel Quijada-Álamo, Jesús María Hernández-Rivas.
3. Arterial identity of hemogenic endothelium: a key to unlock definitive hematopoietic commitment in human pluripotent stem cell cultures
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Igor I. Slukvin, Gene I. Uenishi.
3. Modeling human RNA spliceosome mutations in the mouse: not all mice were created equal
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Jane Jialu Xu, Monique F. Smeets, Shuh Ying Tan, Meaghan Wall, Carl R. Walkley.
3. Establishment and characterization of immortalized erythroid progenitor cell lines derived from a common cell source
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Ryo Kurita, Koji Funato, Takaaki Abe, Yoshihisa Watanabe, Masahiro Satake.
4. Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion
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Toshinobu Nishimura, Ian Hsu, Daniel C. Martinez-Krams, Yusuke Nakauchi, Adam C. Wilkinson.
4. Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia
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Genta Ishikawa, Naoto Fujiwara, Hadassa Hirschfield, Lilian Varricchio, Anna Rita Migliaccio.
4. Rats provide a superior model of human stress erythropoiesis
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Jingxin Zhang, Yijie Liu, Xu Han, Yang Mei, Peng Ji.
4. Increased platelet function during frailty
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Blanca Hernández, Eduardo Fuentes, Iván Palomo, Marcelo Alarcón.
4. Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche
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Yuko Kato, Li-Bo Hou, Satoru Miyagi, Eriko Nitta, Atsushi Iwama.
4. Fetal hemoglobin and F-cell variance in mobilized CD34+ cell-transplanted rhesus monkeys
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4. Human erythroblasts with c-Kit activating mutations have reduced cell culture costs and remain capable of terminal maturations
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Tyler Couch, Zachary Murphy, Michael Getman, Ryo Kurita, Laurie A. Steiner.
4. Difference in megakaryocyte expression of GATA-1, IL-6, and IL-8 associated with maintenance of platelet counts in patients with plasma cell neoplasm with dysmegakaryopoiesis
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Hyunji Kim, Mi-Kyung Lee, Hye Ryoun Kim.
4. ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts
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Tatsufumi Goto, Kumi Ubukawa, Isuzu Kobayashi, Kotomi Sugawara, Wataru Nunomura.
4. Development of innate immune cells from human pluripotent stem cells
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Davide Bernareggi, Somayeh Pouyanfard, Dan S. Kaufman.
4. Functional interdependence of hematopoietic stem cells and their niche in oncogene promotion of myeloproliferative neoplasms: the 159th biomedical version of “it takes two to tango”
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Huichun Zhan, Kenneth Kaushansky.
4. TCF4 promotes erythroid development
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Florentien E.M. in 't Hout, Jolanda van Duren, Davide Monteferrario, Emma Brinkhuis, Gerwin Huls.
5. Identification of miRNAs from stem cell derived microparticles in umbilical cord blood
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Angeliki Xagorari, Marina Gerousi, Antonia Sioga, Dimitris Bougiouklis, Damianos Sotiropoulos.
5. Methylation age as a correlate for allele burden, disease status, and clinical response in myeloproliferative neoplasm patients treated with vorinostat
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Suzanne McPherson, Graeme Greenfield, Christen Andersen, Jacob Grinfeld, Mary F. McMullin.
5. Modest and nonessential roles of the endocannabinoid system in immature hematopoiesis of mice
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Eva Danner, Frauke Hoffmann, Seo-Youn Lee, Fabian Cordes, Halvard Bonig.
5. CTLA4Ig-based reduced intensity conditioning and donor lymphocyte infusions for haploidentical transplantation in refractory aggressive B-cell lymphoma relapsing after an autograft: Early results from a pilot study
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Sarita Rani Jaiswal, Hema Malini Aiyer, Garima Rawat, Arun Gera, Suparno Chakrabarti.
5. Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia
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Jillian L. Jafek, Arvind Shakya, Pei-Yi Tai, Andrea Ibarra, Dean Tantin.
5. Remission clone in acute myeloid leukemia shows growth advantage after chemotherapy but is distinct from leukemic clone
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Jae-Sook Ahn, TaeHyung Kim, Yeo-Kyeoung Kim, Young-Chang Cho, Dennis Dong Hwan Kim.
5. Lipocalin-2 levels in acute and chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation
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Alexander Hermann, Andreas Winkler, Christopher Paschen, Zoya Kuzmina, Oliver Robak.
5. Indirubin regulates MPL and TNF expression in peripheral blood mononuclear cells from patients with primary immune thrombocytopenia
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Kai Shao, Tengkai Wang, Tiantian Li, Aijun Zhang, Ming Hou.
5. Alternative translation initiation generates the N-terminal truncated form of RUNX1 that retains hematopoietic activity
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Tác giả
Susumu Goyama, Janet Schibler, James C. Mulloy.
5. From pluripotent stem cells to T cells
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Tác giả
Amélie Montel-Hagen, Gay M. Crooks.
5. MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells
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Stefan Radtke, Yan-Yi Chan, Trisha R. Sippel, Hans-Peter Kiem, Anthony Rongvaux.
5. Effect of circadian variation on neutrophil mobilization to the peripheral blood in benign constitutional neutropenia
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João Tadeu Damian Souto Filho, Rodrigo Doyle Portugal, Marcio Nucci.
6. Further assessment of stochastic proliferation and its potential application to hematopoietic scaling across species
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Tác giả
Kenneth F. McCarthy.
6. Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies
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Annarita Scialdone, Somayeh Khazaei, Muhammad Sharif Hasni, Andreas Lennartsson, Kristina Drott.
6. Glycolytic enzyme hexokinase II is a putative therapeutic target in B-cell malignant lymphoma
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Kei Nakajima, Ichiro Kawashima, Megumi Koshiisi, Takuma Kumagai, Keita Kirito.
6. BCR-ABL1 tyrosine kinase inhibitor K0706 exhibits preclinical activity in Philadelphia chromosome-positive leukemia
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Orlando Antelope, Nadeem A. Vellore, Anthony D. Pomicter, Ami B. Patel, Thomas O'Hare.
6. Fetal liver Mll-AF4+ hematopoietic stem and progenitor cells respond directly to poly(I:C), but not to a single maternal immune activation
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Tác giả
Camille Malouf, Katrin Ottersbach.
6. PSC-RED and MNC-RED: Albumin-free and low-transferrin robust erythroid differentiation protocols to produce human enucleated red blood cells
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Tác giả
Emmanuel N. Olivier, Shouping Zhang, Zi Yan, Sandra Suzuka, Eric E. Bouhassira.
6. Chronic graft-versus-host disease and the risk of primary disease relapse: A meta-analysis
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Kittika Poonsombudlert, Jakarin Kewcharoen, Chanavuth Kanitsoraphan, Chattip Prueksapraopong, Nath Limpruttidham.
6. KLF1 mutation E325K induces cell cycle arrest in erythroid cells differentiated from congenital dyserythropoietic anemia patient-specific induced pluripotent stem cells
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Hiroshi Kohara, Taiju Utsugisawa, Chika Sakamoto, Lisa Hirose, Kenzaburo Tani.
6. Compounds targeting class II histone deacetylases do not cause panHDACI-associated impairment of megakaryocyte differentiation
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Tác giả
Damir Simic, Nianli Sang.
6. Disease modeling of bone marrow failure syndromes using iPSC-derived hematopoietic stem progenitor cells
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Mahmoud I. Elbadry, J. Luis Espinoza, Shinji Nakao.
6. CircPAN3 mediates drug resistance in acute myeloid leukemia through the miR-153-5p/miR-183-5p–XIAP axis
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Jin Shang, Wei-Min Chen, Zhi-Hong Wang, Tian-Nan Wei, Wen-Bing Wu.
6. Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression
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Genna M. Luciani, Lihua Xie, David Dilworth, Anne Tierens, Mark D. Minden.
7. Inflammatory cytokines promote clonal hematopoiesis with specific mutations in ulcerative colitis patients
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Christine R.C. Zhang, Darren Nix, Martin Gregory, Matthew A. Ciorba, Grant A. Challen.
7. Elevated serum lncRNA TUG1 levels are a potential diagnostic biomarker of multiple myeloma
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Qingqing Yin, Xianjuan Shen, Xiaopeng Cui, Shaoqing Ju.
7. Immature platelet fraction as a useful marker in the etiological determination of thrombocytopenia
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Imtiaz Ali, Ciaren Graham, Nina C. Dempsey-Hibbert.
7. Evolution patterns of paroxysmal nocturnal hemoglobinuria clone and clinical implications in acquired bone marrow failure
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Yu Lian, Jun Shi, Neng Nie, Zhendong Huang, Yizhou Zheng.
7. Human acute myeloid leukemia blast-derived exosomes in patient-derived xenograft mice mediate immune suppression
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Chang-Sook Hong, Gwenn Danet-Desnoyers, Xiaochuan Shan, Priyanka Sharma, Michael Boyiadzis.
7. Maintenance and enhancement of human peripheral blood mobilized stem/progenitor cell engraftment after ex vivo culture via an HDACi/SALL4 axis (3465)
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Hiro Tatetsu, Myriam Armant, Fei Wang, Chong Gao, Li Chai.
7. Acute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1
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Karina Barbosa, Anagha Deshpande, Bo-Rui Chen, Anwesha Ghosh, Aniruddha J. Deshpande.
7. Transcriptional regulators CITED2 and PU.1 cooperate in maintaining hematopoietic stem cells
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Katharina Mattes, Marjan Geugien, Patrick M. Korthuis, Annet Z. Brouwers-Vos, Hein Schepers.
7. Sphingosine-1-phosphate signaling modulates terminal erythroid differentiation through the regulation of mitophagy
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Tác giả
Chong Yang, Michihiro Hashimoto, Quy Xiao Xuan Lin, Darren Qiancheng Tan, Toshio Suda.
7. Application of induced pluripotent stem cells to primary immunodeficiency diseases
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Tác giả
Peter Karagiannis, Shinya Yamanaka, Megumu K. Saito.
7. Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expression
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Saar Shapira, Pia Raanani, Aladin Samara, Arnon Nagler, Galit Granot.
7. Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia
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Yufei Chen, Kenneth L. Jones, Konstantinos Anastassiadis, Andrea Kranz, Patricia Ernst.
8. Yap1 promotes proliferation of transiently amplifying stress erythroid progenitors during erythroid regeneration
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Tác giả
Siyang Hao, Yurika Matsui, Zhi-Chun Lai, Robert F. Paulson.
8. Application of blood and immunodeficiency gene detection in the diagnosis of hemophagocytic lymphohistiocytosis patients
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Tác giả
Wenyuan Mo, Wei Wei, Yan Sun, Yanhong Yang, Zuohua Chi.
8. Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model
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Tác giả
Harit Panda, Nadine Keleku-Lukwete, Ayumi Kuga, Nobuo Fuke, Masayuki Yamamoto.
8. CD97 expression is associated with poor overall survival in acute myeloid leukemia
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Tác giả
Vijaya Pooja Vaikari, Jiawen Yang, Sharon Wu, Houda Alachkar.
8. CD123 CAR T cells for the treatment of myelodysplastic syndrome
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Tác giả
Brett M. Stevens, Wei Zhang, Daniel A. Pollyea, Amanda Winters, Enkhtsetseg Purev.
8. ETV6-RUNX1 interacts with a region in SPIB intron 1 to regulate gene expression in pre-B-cell acute lymphoblastic leukemia
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Tác giả
Li S. Xu, Alyssa Francis, Shereen Turkistany, Devanshi Shukla, Rodney P. DeKoter.
8. Vorinostat synergizes with antioxidant therapy to target myeloproliferative neoplasms
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Tác giả
Bruno A. Cardoso, Teresa L. Ramos, Hélio Belo, Filipe Vilas-Boas, António M. Almeida.
8. Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34+ cells preceding leukemic transformation
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Tác giả
Benjamin Dannenmann, Azadeh Zahabi, Perihan Mir, Benedikt Oswald, Julia Skokowa.
8. Smc3 is required for mouse embryonic and adult hematopoiesis
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Tác giả
Tianjiao Wang, Brandi Glover, Gayla Hadwiger, Christopher A. Miller, John S. Welch.
8. Loss of EfnB1 in the osteogenic lineage compromises their capacity to support hematopoietic stem/progenitor cell maintenance
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Tác giả
Agnieszka Arthur, Thao M. Nguyen, Sharon Paton, Andrew C.W. Zannettino, Stan Gronthos.
9. Erratum to “Engineered humanized bone organs maintain human hematopoiesis in vivo”: [Experimental Hematology 61 (2018) 45–51]
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Kristin Fritsch, Sébastien Pigeot, Xiaomin Feng, Paul E. Bourgine, Hitoshi Takizawa.
9. Modeling malignancies using induced pluripotent stem cells: from chronic myeloid leukemia to hereditary cancers
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Ali Turhan, Adlen Foudi, Jin Wook Hwang, Christophe Desterke, Annelise Bennaceur-Griscelli.
9. MIR-144-mediated NRF2 gene silencing inhibits fetal hemoglobin expression in sickle cell disease
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Biaoru Li, Xingguo Zhu, Christina M. Ward, Athena Starlard-Davenport, Betty S. Pace.
9. Interleukin-18 plays a dispensable role in murine and likely also human bone marrow failure
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Tác giả
Zhijie Wu, Valentina Giudice, Jichun Chen, Wanling Sun, Neal S. Young.
10. Induced pluripotent stem cell modeling of malignant hematopoiesis
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Tác giả
Mark P. Chao, Ravindra Majeti.
10. Targeting cell-bound MUC1 on myelomonocytic, monocytic leukemias and phenotypically defined leukemic stem cells with anti-SEA module antibodies
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Tác giả
Thierry Guillaume, Virginie Dehame, Patrice Chevallier, Pierre Peterlin, Daniel H. Wreschner.
11. Modeling myeloid malignancies with patient-derived iPSCs
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Tác giả
Eirini P. Papapetrou.