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Acta Pharmaceutica Sinica B
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Volume 9, Issue 5
Pages 871-1086 (September 2019)
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1. Table of Contents
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2. Targeting the untargetable KRAS in cancer therapy
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Tác giả
Pingyu Liu, Yijun Wang, Xin Li.
3. Structural simplification: an efficient strategy in lead optimization
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Tác giả
Shengzheng Wang, Guoqiang Dong, Chunquan Sheng.
4. Multifunctional oral delivery systems for enhanced bioavailability of therapeutic peptides/proteins
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Tác giả
Ying Han, Zhonggao Gao, Liqing Chen, Lin Kang, You Han Bae.
5. Inactivation of TFEB and NF-κB by marchantin M alleviates the chemotherapy-driven pro-tumorigenic senescent secretion
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Tác giả
Huanmin Niu, Lilin Qian, Bin Sun, Wenjian Liu, Huiqing Yuan.
6. Synergistic antitumor activity of artesunate and HDAC inhibitors through elevating heme synthesis via synergistic upregulation of ALAS1 expression
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Cai-Ping Chen, Kun Chen, Zhiqi Feng, Xiaoan Wen, Hongbin Sun.
7. Direct interaction of DNMT inhibitors to PrPC suppresses pathogenic process of prion
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Tác giả
Dae-Hwan Kim, Chunyan Ren, Chongsuk Ryou, Jiaojie Li.
8. Improvement in affinity and thermostability of a fully human antibody against interleukin-17A by yeast-display technology and CDR grafting
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Tác giả
Wei Sun, Zhaona Yang, Heng Lin, Ming Liu, Bing Cui.
9. Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes
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Tác giả
Feng Zhou, Jingtian Mei, Xiuguo Han, Hanjun Li, Tingting Tang.
10. Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)
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Tác giả
Xiaokui Huo, Qiang Meng, Changyuan Wang, Yanna Zhu, Kexin Liu.
11. Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1
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Tác giả
AlexanderJ. Trevarton, Yan Zhou, Dehua Yang, Gordon W. Rewcastle, Annette Lasham.
12. Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2
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Tác giả
Lu Chen, Le Chen, Zhiyuan Qin, Jinxiu Lei, Lushan Yu.
13. MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
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Tác giả
Sara Abdelfatah, Angela Berg, Qi Huang, Li Jun Yang, Thomas Efferth.
14. High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care
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Tác giả
Jian Li, Olajide E. Olaleye, Xuan Yu, Weiwei Jia, Chuan Li.
15. Injectable peptide hydrogel as intraperitoneal triptolide depot for the treatment of orthotopic hepatocellular carcinoma
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Xiyue Zhao, Xiaoyu Liu, Pengcheng Zhang, Yiran Liu, Yaping Li.
16. Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer
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Tác giả
Dong Mei, Binlong Chen, Bing He, Haibin Liu, Qiang Zhang.
17. The dimerization of Δ9-tetrahydrocannabinolic acid A (THCA-A)
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Tác giả
Arben Cuadari, Federica Pollastro, Juan D. Unciti-Broceta, Diego Caprioglio, Giovanni Appendino.
18. New era of drug innovation in China
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Tác giả
Xuan Ye, Qingli Wang, Haixue Wang.
