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Cancer Immunology, Immunotherapy
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1. Autophagy inhibition induces the repolarisation of tumour-associated macrophages and enhances chemosensitivity of laryngeal cancer cells to cisplatin in mice
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Tác giả
Ying Guo, Yufang Feng, Xinhua Cui, Qirong Wang.
1. The prognostic significance of peritumoral tertiary lymphoid structures in breast cancer
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Tác giả
Michael Sofopoulos, Sotirios P. Fortis.
1. Presence of T cells directed against CD20-derived peptides in healthy individuals and lymphoma patients
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Tác giả
Benoit Milcent, Nathalie Josseaume, Quentin Riller.
1. Anti-CAR-engineered T cells for epitope-based elimination of autologous CAR T cells
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Tác giả
Stefanie Koristka, Pauline Ziller-Walter, Ralf Bergmann.
1. Intratumoral plasmacytoid dendritic cells as a poor prognostic factor for hepatocellular carcinoma following curative resection
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Tác giả
Zheng-Jun Zhou, Hao-Yang Xin, Jia Li, Zhi-Qiang Hu.
1. PLAC1: biology and potential application in cancer immunotherapy
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Tác giả
Jafar Mahmoudian, Roya Ghods, Mahboobeh Nazari.
1. Absolute numbers of regulatory T cells and neutrophils in corticosteroid-free patients are predictive for response to bevacizumab in recurrent glioblastoma patients
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Tác giả
Véronique Quillien, Antoine F. Carpentier, Alain Gey.
1. T-cell recognition of non-mutated tumor antigens in healthy individuals: connecting endogenous immunity and tumor dormancy
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Tác giả
Constantin N. Baxevanis.
1. MDSC and beyond: a symposium-in-writing on myeloid cells with immunoregulatory activity by members of the Mye-EUNITER network
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Tác giả
Sven Brandau.
1. Immunotherapy with checkpoint inhibitors in non-small cell lung cancer: insights from long-term survivors
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Tác giả
Ernest Nadal, Bartomeu Massuti, Manuel Dómine.
1. Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade
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Tác giả
Hanna Grauers Wiktorin, Malin S. Nilsson.
1. Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy
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Tác giả
Michele Maio, George Coukos, Soldano Ferrone.
2. Pembrolizumab for anaplastic thyroid cancer: a case study
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Tác giả
Marra Jai Aghajani, Adam Cooper, Helen McGuire.
2. Potential clinical application of tumor-infiltrating lymphocyte therapy for ovarian epithelial cancer prior or post-resistance to chemotherapy
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Tác giả
Donastas Sakellariou-Thompson, Marie-Andrée Forget.
2. Desmoid tumors display a strong immune infiltration at the tumor margins and no PD-L1-driven immune suppression
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Tác giả
Vasiliki Siozopoulou, Elly Marcq, Julie Jacobs.
2. Successful combination therapy of systemic checkpoint inhibitors and intralesional interleukin-2 in patients with metastatic melanoma with primary therapeutic resistance to checkpoint inhibitors alone
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Tác giả
David Rafei-Shamsabadi, Saskia Lehr, Dagmar von Bubnoff.
2. Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
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Tác giả
Nadia Mensali, Marit Renée Myhre, Pierre Dillard.
2. Cryptotanshinone has curative dual anti-proliferative and immunotherapeutic effects on mouse Lewis lung carcinoma
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Tác giả
Shuo Liu, Zhen Han, Anna L. Trivett, Hongsheng Lin.
2. HCT-116 colorectal cancer cells secrete chemokines which induce chemoattraction and intracellular calcium mobilization in NK92 cells
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Tác giả
Noha Mousaad Elemam, Zaidoon Al-Jaderi.
2. Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans
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Tác giả
Anna Przybyla, Ting Zhang, Ruliang Li, Diana R. Roen.
2. Strong antigen-specific T-cell immunity induced by a recombinant human TERT measles virus vaccine and amplified by a DNA/viral vector prime boost in IFNAR/CD46 mice
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Tác giả
Elodie Pliquet, Claude Ruffie, Marie Escande.
2. The correlation and prognostic value of serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death-ligand 1 (sPD-L1) in patients with hepatocellular carcinoma
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Tác giả
Boyang Chang, Tao Huang, Huajun Wei, Lujun Shen.
2. The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth
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Tác giả
Tyler R. McCaw, Mei Li, Dmytro Starenki, Sara J. Cooper.
2. β-Adrenergic signaling blocks murine CD8+ T-cell metabolic reprogramming during activation: a mechanism for immunosuppression by adrenergic stress
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Tác giả
Guanxi Qiao, Mark J. Bucsek, Nicolette M. Winder.
3. Regulatory T cells induce CD4− NKT cell anergy and suppress NKT cell cytotoxic function
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Tác giả
Fumie Ihara, Daiju Sakurai, Mariko Takami.
3. Neoadjuvant cisplatin and paclitaxel modulate tumor-infiltrating T cells in patients with cervical cancer
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Tác giả
A. Marijne Heeren, Iske F. van Luijk, Joost Lakeman.
3. Peripheral changes in immune cell populations and soluble mediators after anti-PD-1 therapy in non-small cell lung cancer and renal cell carcinoma patients
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Tác giả
Estefanía Paula Juliá, Pablo Mandó.
3. A VEGFR2–MICA bispecific antibody activates tumor-infiltrating lymphocytes and exhibits potent anti-tumor efficacy in mice
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Tác giả
Yao Xu, Xinrong Zhang, Yong Wang, Mingzhu Pan, Min Wang.
3. Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)
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Tác giả
Despoina Koumantou, Eilon Barnea, Adrian Martin-Esteban.
3. Inhibition of murine hepatoma tumor growth by cryptotanshinone involves TLR7-dependent activation of macrophages and induction of adaptive antitumor immune defenses
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Tác giả
Zhen Han, Shuo Liu, Hongsheng Lin, Anna L. Trivett.
3. Autoimmune genetic risk variants as germline biomarkers of response to melanoma immune-checkpoint inhibition
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Tác giả
Vylyny Chat, Robert Ferguson, Danny Simpson.
3. Imbalances in cellular immunological parameters in blood predetermine tumor onset in a natural mouse model of breast cancer
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Tác giả
Dmitry A. Aronov, Viacheslav V. Zhukov.
3. Adverse events need for hospitalization and systemic immunosuppression in very elderly patients (over 80 years) treated with ipilimumab for metastatic melanoma
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Tác giả
Vaianu Leroy, Emilie Gerard, Caroline Dutriaux.
3. CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions
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Tác giả
Wanghong Hu, Zhenguo Zi, Yanling Jin, Gaoxin Li.
3. INT-HA induces M2-like macrophage differentiation of human monocytes via TLR4-miR-935 pathway
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Tác giả
Boke Zhang, Yan Du, Yiqing He, Yiwen Liu.
3. Sustained efficacy of adjuvant immunotherapy with cytokine-induced killer cells for hepatocellular carcinoma: an extended 5-year follow-up
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Tác giả
Jeong-Hoon Lee, Joon Hyeok Lee, Young-Suk Lim.
4. Combining alpha radiation-based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor-specific long-term immune response
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Tác giả
Vered Domankevich, Adi Cohen, Margalit Efrati.
4. Contribution of Fcγ receptor IIB to creating a suppressive tumor microenvironment in a mouse model
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Tác giả
Yuki Kasahara, Hidekazu Shirota, Sho Umegaki.
4. ANTXR1 (TEM8) overexpression in gastric adenocarcinoma makes the protein a potential target of immunotherapy
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Tác giả
Masoud Sotoudeh, Ramin Shakeri, Sanford M. Dawsey.
4. Morphomolecular analysis of the immune tumor microenvironment in human head and neck cancer
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Tác giả
Mohamed Badr, Korinna Jöhrens, Michael Allgäuer.
4. High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer
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Tác giả
Timo Carpén, Timo Sorsa, Lauri Jouhi.
4. Novel circulating tumor cell-based blood test for the assessment of PD-L1 protein expression in treatment-naïve, newly diagnosed patients with non-small cell lung cancer
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Tác giả
Yen-Lin Chen, Wen-Chien Huang, Feng-Ming Lin.
4. DNA lesions correlate with lymphocyte function after selective internal radiotherapy
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Tác giả
Aglaia Domouchtsidou, Vahé Barsegian, Stefan P. Mueller.
4. Tumor infiltrating mast cells determine oncogenic HIF-2α-conferred immune evasion in clear cell renal cell carcinoma
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Tác giả
Ying Xiong, Li Liu, Yu Xia, Yangyang Qi, Yifan Chen.
4. Immune checkpoint inhibitor-induced colitis as a predictor of survival in metastatic melanoma
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Tác giả
Hamzah Abu-Sbeih, Faisal S. Ali, Wei Qiao, Yang Lu.
4. Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model
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Tác giả
Diana Llopiz, Marta Ruiz, Lorea Villanueva.
4. Inhibitory functions of PD-L1 and PD-L2 in the regulation of anti-tumor immunity in murine tumor microenvironment
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Tác giả
Daisuke Umezu, Nana Okada, Yukimi Sakoda, Keishi Adachi.
4. TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression
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Tác giả
Maya Gershkovitz, Tanya Fainsod-Levi, Tamir Zelter.
5. Activated hepatic stellate cells regulate MDSC migration through the SDF-1/CXCR4 axis in an orthotopic mouse model of hepatocellular carcinoma
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Tác giả
Yaping Xu, Fei Fang, Hui Jiao, Xiaohui Zheng.
5. Clinicopathologic significance of human leukocyte antigen class I expression in patients with stage II and III gastric cancer
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Tác giả
Yujun Park, Jiwon Koh, Yoonjin Kwak, Sang-Hoon Ahn.
5. Induction of tumor-specific CD8+ cytotoxic T lymphocytes from naïve human T cells by using Mycobacterium-derived mycolic acid and lipoarabinomannan-stimulated dendritic cells
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Tác giả
Yuji Tomita, Eri Watanabe, Masumi Shimizu.
5. Melanoma-conditioned medium promotes cytotoxic immune responses by murine bone marrow-derived monocytes despite their expression of ‘M2’ markers
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Tác giả
Liam Friel Tremble, Anne C. Moore, Patrick F. Forde.
5. Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model
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Tác giả
Eiichi Ishida, Jina Lee, Jean S. Campbell.
5. Checkpoint blockade immunotherapy enhances the frequency and effector function of murine tumor-infiltrating T cells but does not alter TCRβ diversity
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Tác giả
Lindsey M. Kuehm, Kyle Wolf, John Zahour.
5. Pre-existing autoimmune disease and the risk of immune-related adverse events among patients receiving checkpoint inhibitors for cancer
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Tác giả
Kenneth L. Kehl, Shihao Yang, Mark M. Awad.
5. Melanoma-associated antigen-A and programmed death-ligand 1 expression are associated with advanced urothelial carcinoma
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Tác giả
Izak Faiena, Stephanie H. Astrow, David A. Elashoff.
5. Prognostic value of tumour-infiltrating CD8+ lymphocytes in rectal cancer after neoadjuvant chemoradiation: is indoleamine-2,3-dioxygenase (IDO1) a friend or foe?
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Tác giả
Julia Schollbach, Stefan Kircher, Armin Wiegering.
5. Ex vivo conditioning with IL-12 protects tumor-infiltrating CD8+ T cells from negative regulation by local IFN-γ
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Tác giả
Lin Lin, Patricia Rayman, Paul G. Pavicic Jr.
5. Analysis of tumor-infiltrating CD103 resident memory T-cell content in recurrent laryngeal squamous cell carcinoma
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Tác giả
Jacqueline E. Mann, Joshua D. Smith.
5. CD19+ tumor-infiltrating B-cells prime CD4+ T-cell immunity and predict platinum-based chemotherapy efficacy in muscle-invasive bladder cancer
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Tác giả
Qi Jiang, Qiang Fu, Yuan Chang, Zheng Liu, Junyu Zhang.
6. Identification of prognostic genes in the acute myeloid leukemia immune microenvironment based on TCGA data analysis
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Tác giả
Haimeng Yan, Jianwei Qu, Wen Cao, Yang Liu.
6. Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine
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Tác giả
Caterina Lapenta, Simona Donati, Francesca Spadaro.
6. The BRCA2 mutation status shapes the immune phenotype of prostate cancer
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Tác giả
Maximilian Jenzer, Peter Keß, Cathleen Nientiedt.
6. Safety and efficacy of PD-1 blockade-activated multiple antigen-specific cellular therapy alone or in combination with apatinib in patients with advanced solid tumors: a pooled analysis of two prospective trials
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Tác giả
Lijun Liang, Yixuan Wen, Rong Hu, Lei Wang, Youyou Xia.
6. Reduced CTL motility and activity in avascular tumor areas
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Tác giả
Yoav Manaster, Zohar Shipony, Anat Hutzler.
6. Metabolic remodeling contributes towards an immune-suppressive phenotype in glioblastoma
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Tác giả
Pravin Kesarwani, Antony Prabhu, Shiva Kant.
6. An immunosuppressive macrophage profile attenuates the prognostic impact of CD20-positive B cells in human soft tissue sarcoma
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Tác giả
Panagiotis Tsagozis, Martin Augsten, Yifan Zhang.
6. Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model
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Tác giả
Jamile R. Silva, Natiely S. Sales, Mariângela O. Silva.
6. A potential role for peripheral natural killer cell activity induced by preoperative chemotherapy in breast cancer patients
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Tác giả
Ryungsa Kim, Ami Kawai, Megumi Wakisaka, Yuri Funaoka.
6. Identification and characterization of an alternative cancer-derived PD-L1 splice variant
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Tác giả
Nadia B. Hassounah, Venkat S. Malladi, Yi Huang.
6. Stromal interleukin-33 promotes regulatory T cell-mediated immunosuppression in head and neck squamous cell carcinoma and correlates with poor prognosis
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Tác giả
Yi-hui Wen, Han-qing Lin, Hang Li, Yi Zhao.
6. Serum miRNA-based distinct clusters define three groups of breast cancer patients with different clinicopathological and immune characteristics
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Tác giả
Sotirios P. Fortis, Christoforos K. Vaxevanis.
7. Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma
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Tác giả
Yuexin Xu, Alicia J. Morales, Michael J. Cargill.
7. Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation
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Tác giả
Anthony L. Schwartz, Pulak R. Nath, Michael Allgauer.
7. Gastrin vaccine improves response to immune checkpoint antibody in murine pancreatic cancer by altering the tumor microenvironment
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Tác giả
Nicholas Osborne, Rebecca Sundseth, Julian Burks.
7. An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activation
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Tác giả
Luciano Castiello, Alessandra Zevini, Elisabetta Vulpis.
7. Mouse CD8+NKT-like cells exert dual cytotoxicity against mouse tumor cells and myeloid-derived suppressor cells
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Tác giả
Zhengyuan Li, Yiqing Wu, Chao Wang, Minghui Zhang.
7. Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors
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Tác giả
Katie M. Leick, Joel Pinczewski, Ileana S. Mauldin.
7. Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma
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Tác giả
Kim C. M. Santegoets, Paul R. Gielen, Christian Büll.
7. First-line therapy-stratified survival in BRAF-mutant melanoma: a retrospective multicenter analysis
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Tác giả
Bastian Schilling, Alexander Martens.
7. Mutations resulting in the formation of hyperactive complement convertases support cytocidal effect of anti-CD20 immunotherapeutics
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Tác giả
Anna Felberg, Aleksandra Urban, Anna Borowska.
7. A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression
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Tác giả
Kathleen M. Mahoney, Sachet A. Shukla.
7. Development of CDX-1140, an agonist CD40 antibody for cancer immunotherapy
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Tác giả
Laura A. Vitale, Lawrence J. Thomas, Li-Zhen He.
7. An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells
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Tác giả
Michele Tomasicchio, Lynn Semple, Aliasgar Esmail.
8. Predominance of M2 macrophages in gliomas leads to the suppression of local and systemic immunity
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Tác giả
Aurobind Vidyarthi, Tapan Agnihotri, Nargis Khan.
8. Schwann cells shape the neuro-immune environs and control cancer progression
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Tác giả
German V. Martyn, Galina V. Shurin, Anton A. Keskinov.
8. PTPN3 expressed in activated T lymphocytes is a candidate for a non-antibody-type immune checkpoint inhibitor
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Tác giả
Akiko Fujimura, Kazunori Nakayama, Akira Imaizumi.
8. TNFSF4 (OX40L) expression and survival in locally advanced and metastatic melanoma
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Tác giả
Jason Roszik, Ettai Markovits, Paula Dobosz, Adi Layani.
8. Interferon beta increases NK cell cytotoxicity against tumor cells in patients with nasopharyngeal carcinoma via tumor necrosis factor apoptosis-inducing ligand
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Tác giả
Anna Makowska, Sabrina Franzen, Till Braunschweig.
8. Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma
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Tác giả
Sonja Ludwig, Chang-Sook Hong, Beatrice M. Razzo.
8. Heterogeneity of PD-L1 expression and CD8 tumor-infiltrating lymphocytes among subtypes of cutaneous adnexal carcinomas
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Tác giả
Lucie Duverger, Amélie Osio, Bernard Cribier.
8. Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2
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Tác giả
Linh T. Nguyen, Samuel D. Saibil, Valentin Sotov.
8. The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma
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Tác giả
David Agdashian, Mei ElGindi, Changqing Xie.
8. Immune cell infiltration as a biomarker for the diagnosis and prognosis of stage I–III colon cancer
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Tác giả
Rui Zhou, Jingwen Zhang, Dongqiang Zeng, Huiying Sun.
8. The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications for vaccine design
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Tác giả
Matthieu Besneux, Alexander Greenshields-Watson.
8. Recurrent grade 4 panuveitis with serous retinal detachment related to nivolumab treatment in a patient with metastatic renal cell carcinoma
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Tác giả
Wei Wang, Wai-Ching Lam, Ling Chen.
9. Serum very long-chain fatty acid-containing lipids predict response to immune checkpoint inhibitors in urological cancers
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Tác giả
Andreas Mock, Stefanie Zschäbitz, Romy Kirsten.
9. The challenges of adoptive cell transfer in the treatment of human renal cell carcinoma
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Tác giả
Zuzana Strizova, Jirina Bartunkova, Daniel Smrz.
9. Increased indoleamine 2,3-dioxygenase activity and expression in prostate cancer following targeted immunotherapy
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Tác giả
Chris D. Zahm, Laura E. Johnson, Douglas G. McNeel.
9. Tumor-induced peripheral immunosuppression promotes brain metastasis in patients with non-small cell lung cancer
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Tác giả
Yuping D. Li, Jonathan B. Lamano, Jason B. Lamano.
9. Immunity to X-linked inhibitor of apoptosis protein (XIAP) in malignant melanoma and check-point blockade
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Tác giả
Jun Zhou, Jingjing Li, Indira Guleria, Tianqi Chen.
9. An HER2 DNA vaccine with evolution-selected amino acid substitutions reveals a fundamental principle for cancer vaccine formulation in HER2 transgenic mice
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Tác giả
Richard F. Jones, Joyce D. Reyes, Heather M. Gibson.
9. Sirtuin2 enhances the tumoricidal function of liver natural killer cells in a mouse hepatocellular carcinoma model
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Tác giả
Ming Chen, Min Xu, Chengliang Zhu, Hongling Wang.
9. Metronomic cyclophosphamide attenuates mTOR-mediated expansion of regulatory T cells, but does not impact clinical outcome in patients with metastatic renal cell cancer treated with everolimus
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Tác giả
Inge M. Werter, Charlotte M. Huijts.
9. Early objective response to avelumab treatment is associated with improved overall survival in patients with metastatic Merkel cell carcinoma
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Tác giả
Sandra P. D’Angelo, Matthias Hunger, Andrew S. Brohl.
9. Distinct immunological properties of the two histological subtypes of adenocarcinoma of the ampulla of Vater
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Tác giả
Min Hwan Kim, Mi Jang, Hoguen Kim, Woo Jung Lee.
9. Hyperresponsiveness to interferon gamma exposure as a response mechanism to anti-PD-1 therapy in microsatellite instability colorectal cancer
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Tác giả
Wenli Yuan, Deyao Deng, Hongchao Jiang, Changling Tu.
9. Soluble CTLA-4 as a favorable predictive biomarker in metastatic melanoma patients treated with ipilimumab: an Italian melanoma intergroup study
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Tác giả
Maria Pia Pistillo, Vincenzo Fontana, Anna Morabito.
10. Tumor genetic alterations and features of the immune microenvironment drive myelodysplastic syndrome escape and progression
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Tác giả
Paola Montes, Mónica Bernal, Laura N. Campo.
10. Naturally occurring cancers in pet dogs as pre-clinical models for cancer immunotherapy
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Tác giả
Lidia Tarone, Giuseppina Barutello, Selina Iussich.
10. Sirtuin2 enhances the tumoricidal function of liver natural killer cells in a mouse hepatocellular carcinoma model
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Tác giả
Ming Chen, Min Xu, Chengliang Zhu, Hongling Wang.
10. The role of immune infiltrates as prognostic biomarkers in patients with breast cancer
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Tác giả
Constantin N. Baxevanis, Michael Sofopoulos.
10. Lymphocyte-specific kinase expression is a prognostic indicator in ovarian cancer and correlates with a prominent B cell transcriptional signature
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Tác giả
Emily Hinchcliff, Cherie Paquette, Jason Roszik.
10. Peri-operative monocyte count is a marker of poor prognosis in gastric cancer: increased monocytes are a characteristic of myeloid-derived suppressor cells
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Tác giả
Shinya Urakawa, Makoto Yamasaki, Kumiko Goto.
10. Clinicopathological implications of TIM3+ tumor-infiltrating lymphocytes and the miR-455-5p/Galectin-9 axis in skull base chordoma patients
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Tác giả
Jinpeng Zhou, Yang Jiang, Haiying Zhang, Lian Chen.
10. Immune-phenotyping of pleomorphic dermal sarcomas suggests this entity as a potential candidate for immunotherapy
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Tác giả
Sebastian Klein, Cornelia Mauch, Svenja Wagener-Ryczek.
10. A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer
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Tác giả
Martin Sebastian, Andreas Schröder, Birgit Scheel.
10. A pilot study of interferon-alpha-2b dose reduction in the adjuvant therapy of high-risk melanoma
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Tác giả
Lorena P. Suarez-Kelly, Kala M. Levine.
10. The route of administration dictates the immunogenicity of peptide-based cancer vaccines in mice
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Tác giả
Hussein Sultan, Takumi Kumai, Toshihiro Nagato, Juan Wu.
10. Targeting the polarization of tumor-associated macrophages and modulating mir-155 expression might be a new approach to treat diffuse large B-cell lymphoma of the elderly
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Tác giả
Wagner A. Poles, Erika E. Nishi, Mariana B. de Oliveira.
10. Association of IL-36γ with tertiary lymphoid structures and inflammatory immune infiltrates in human colorectal cancer
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Tác giả
Aliyah M. Weinstein, Nicolas A. Giraldo.
11. ISG15 pathway knockdown reverses pancreatic cancer cell transformation and decreases murine pancreatic tumor growth via downregulation of PDL-1 expression
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Tác giả
Julian Burks, Alia Fleury, Sarah Livingston.
11. Adhering to adhesion: assessing integrin conformation to monitor T cells
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Tác giả
Cécile Gouttefangeas, Juliane Schuhmacher.
11. Unlocking the therapeutic potential of primary tumor-draining lymph nodes
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Tác giả
Jossie Rotman, Bas D. Koster, Ekaterina S. Jordanova.
11. Anti-PD-1 therapy combined with chemotherapy in patients with advanced biliary tract cancer
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Tác giả
Danyang Sun, Junxun Ma, Jinliang Wang, Chun Han.
11. Serum PCSK9 levels at the second nivolumab cycle predict overall survival in elderly patients with NSCLC: a pilot study
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Tác giả
Aldo Bonaventura, Francesco Grossi, Federico Carbone.
11. Evaluation of the efficacy of immunotherapy for non-resectable mucosal melanoma
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Tác giả
Antoine Moya-Plana, Ruth Gabriela Herrera Gómez.
11. MHC class-I downregulation in PD-1/PD-L1 inhibitor refractory Merkel cell carcinoma and its potential reversal by histone deacetylase inhibition: a case series
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Tác giả
Selma Ugurel, Ivelina Spassova, Jonas Wohlfarth.
11. Monitoring of patients with metastatic melanoma treated with immune checkpoint inhibitors using PET–CT
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Tác giả
Antonia Dimitrakopoulou-Strauss.
11. How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions
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Tác giả
Annika M. Bruger, Anca Dorhoi, Gunes Esendagli.
11. CD73 expression in normal and pathological human hepatobiliopancreatic tissues
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Tác giả
Amedeo Sciarra, Inês Monteiro, Christine Ménétrier-Caux.
11. Upregulation of tumor PD-L1 by neoadjuvant chemoradiotherapy (neoCRT) confers improved survival in patients with lymph node metastasis of locally advanced rectal cancers
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Tác giả
Shu-Fen Chiang, Chih-Yang Huang, Tao-Wei Ke.
11. Phase I/II clinical trial of a Wilms’ tumor 1-targeted dendritic cell vaccination-based immunotherapy in patients with advanced cancer
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Tác giả
Wen Zhang, Xu Lu, Peilin Cui, Chunmei Piao, Man Xiao.
12. PD-1+ TIGIT+ CD8+ T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma
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Tác giả
Xiaoli Liu, Mengge Li, Xinhui Wang, Zhibo Dang.
12. CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models
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Tác giả
Bjarne Bogen, Marte Fauskanger, Ole Audun Haabeth.
12. Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapy
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Tác giả
Michael Friedrich, Simon Jasinski-Bergner.
12. Independent expression of circulating and tissue levels of PD-L1: correlation of clusters with tumor metabolism and outcome in patients with non-small cell lung cancer
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Tác giả
Fabio Grizzi, Angelo Castello, Dorina Qehajaj.
12. CTLA-4 antibody ipilimumab negatively affects CD4+ T-cell responses in vitro
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Tác giả
Sandra Rosskopf, Judith Leitner, Gerhard J. Zlabinger.
12. Pembrolizumab as first-line treatment for metastatic uveal melanoma
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Tác giả
Ernesto Rossi, Monica Maria Pagliara, Daniela Orteschi.
12. Age and sex have no impact on expression levels of markers of immune cell infiltration and immune checkpoint pathways in patients with muscle-invasive urothelial carcinoma of the bladder treated with radical cystectomy
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Bradley C. Holland, Akshay Sood, Kristin Delfino.
12. Opposing roles of eosinophils in cancer
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Sonja C. S. Simon, Jochen Utikal, Viktor Umansky.
12. Interactions among myeloid regulatory cells in cancer
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Viktor Umansky, Gosse J. Adema, Jaroslaw Baran.
12. Chronic retroviral infection of mice promotes tumor development, but CD137 agonist therapy restores effective tumor immune surveillance
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Anna Malyshkina, Elisabeth Littwitz-Salomon.
12. Can benign lymphoid tissue changes in 18F-FDG PET/CT predict response to immunotherapy in metastatic melanoma?
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Christos Sachpekidis, Lionel Larribère.
12. Fighting breast cancer stem cells through the immune-targeting of the xCT cystine–glutamate antiporter
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Roberto Ruiu, Valeria Rolih, Elisabetta Bolli.
13. Role of regulatory T cells and checkpoint inhibition in hepatocellular carcinoma
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Bettina Langhans, Hans Dieter Nischalke.
13. Activation of dendritic cells by targeted DNA: a potential addition to the armamentarium for anti-cancer immunotherapy
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Marlene Fyrstenberg Laursen, Emil Kofod-Olsen.
13. T cell engineering for adoptive T cell therapy: safety and receptor avidity
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Elvira D’Ippolito, Kilian Schober, Magdalena Nauerth.
13. A phase II study of the L19IL2 immunocytokine in combination with dacarbazine in advanced metastatic melanoma patients
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Benjamin Weide, Thomas Eigentler, Chiara Catania.
13. Histopathology-based immunoscore predicts recurrence for intrahepatic cholangiocarcinoma after hepatectomy
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Meng-Xin Tian, Yu-Fu Zhou, Wei-Feng Qu, Wei-Ren Liu.
13. Combination of denosumab and immune checkpoint inhibition: experience in 29 patients with metastatic melanoma and bone metastases
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Yenny Angela, Sebastian Haferkamp, Carsten Weishaupt.
13. Systemic and local immunosuppression in patients with high-grade meningiomas
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Yuping D. Li, Dorina Veliceasa, Jason B. Lamano.
13. Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism
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Jingjing Zhu, Pierre-Florent Petit.
13. Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation
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Giada Amodio, Joanna Cichy, Patricia Conde.
13. STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes
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Morten Nørgaard Andersen, Anders Etzerodt.
13. Tumor-infiltrating immune cell subpopulations and programmed death ligand 1 (PD-L1) expression associated with clinicopathological and prognostic parameters in ependymoma
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Soo Jeong Nam, Young-Hoon Kim, Ji Eun Park.
13. The Italian Network for Tumor Bio-Immunotherapy (NIBIT) Foundation: ongoing and prospective activities in immuno-oncology
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Anna Maria Di Giacomo, Alessia Covre.
14. Tumor-associated macrophages expressing galectin-9 identify immunoevasive subtype muscle-invasive bladder cancer with poor prognosis but favorable adjuvant chemotherapeutic response
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Yangyang Qi, Yuan Chang, Zewei Wang, Lingli Chen.
14. Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy
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Timothy T. Spear, Brian D. Evavold, Brian M. Baker.
14. Conventional CARs versus modular CARs
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Anja Feldmann, Claudia Arndt, Stefanie Koristka.
14. An IL-15-based superagonist ALT-803 enhances the NK cell response to cetuximab-treated squamous cell carcinoma of the head and neck
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Ashley Pinette, Elizabeth McMichael.
14. Comparison of IL-2 vs IL-7/IL-15 for the generation of NY-ESO-1-specific T cells
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Wenjie Gong, Jean-Marc Hoffmann, Sophia Stock, Lei Wang.
14. Characterization of circulating T-, NK-, and NKT cell subsets in patients with colorectal cancer: the peripheral blood immune cell profile
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Daniëlle Krijgsman, Natasja L. de Vries, Anni Skovbo.
14. An alphavirus-based therapeutic cancer vaccine: from design to clinical trial
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Amrita Singh, Georgia Koutsoumpli.
14. MDSCs in infectious diseases: regulation, roles, and readjustment
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Anca Dorhoi, Estibaliz Glaría, Thalia Garcia-Tellez.
14. The effect of everolimus and low-dose cyclophosphamide on immune cell subsets in patients with metastatic renal cell carcinoma: results from a phase I clinical trial
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Charlotte M. Huijts, Sinéad M. Lougheed, Zuhir Bodalal.
14. Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma
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Charlotte M. Huijts, Inge M. Werter, Sinéad M. Lougheed.
14. Fifteenth Meeting of the Network Italiano per la Bioterapia dei Tumori (NIBIT) on Cancer Bio-Immunotherapy, Siena, Italy, October 5–7, 2017
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Michele Maio, Maria Fortunata Lofiego, Carolina Fazio.
15. Histone deacetylase inhibition promotes intratumoral CD8+ T-cell responses, sensitizing murine breast tumors to anti-PD1
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Tyler R. McCaw, Mei Li, Dmytro Starenki, Mingyong Liu.
15. Monocytes reprogrammed with lentiviral vectors co-expressing GM-CSF, IFN-α2 and antigens for personalized immune therapy of acute leukemia pre- or post-stem cell transplantation
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Julia K. Bialek-Waldmann, Michael Heuser, Arnold Ganser.
15. Natural killer cells control metastasis via structural editing of primary tumors in mice
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Batya Isaacson, Ofer Mandelboim.
15. 4th Symposium on Advances in Cancer Immunology and Immunotherapy, November 29–December 1, 2018, Athens, Greece
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Sotirios P. Fortis, Athanasios Kotsakis.
15. First-in-human phase 1 dose-escalating trial of G305 in patients with advanced solid tumors expressing NY-ESO-1
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Amit Mahipal, Samuel Ejadi, Sacha Gnjatic.
15. Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial
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Bas D. Koster, Saskia J. A. M. Santegoets.
15. Modulation of NK cells with checkpoint inhibitors in the context of cancer immunotherapy
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Beatriz Sanchez-Correa, Nelson Lopez-Sejas.
15. Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates
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Luca Cassetta, Espen S. Baekkevold, Sven Brandau.
15. Randomized-controlled phase II trial of salvage chemotherapy after immunization with a TP53-transfected dendritic cell-based vaccine (Ad.p53-DC) in patients with recurrent small cell lung cancer
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Alberto A. Chiappori, Charles C. Williams.
15. A phase I clinical study of a cocktail vaccine of Wilms’ tumor 1 (WT1) HLA class I and II peptides for recurrent malignant glioma
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Akihiro Tsuboi, Naoya Hashimoto, Fumihiro Fujiki.
15. Prediction of neoepitopes from murine sequencing data
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Anne-Mette Bjerregaard, Thomas Kainamura Pedersen.
16. Arginase-1-based vaccination against the tumor microenvironment: the identification of an optimal T-cell epitope
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Evelina Martinenaite, Shamaila Munir Ahmad.
16. “Tumor Immunology Meets Oncology (TIMO) XIV”, May 24–26th 2018, Halle/Saale, Germany
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André Steven, Barbara Seliger.
16. Correction to: Autologous tumor cell vaccination combined with systemic CpG-B and IFN-α promotes immune activation and induces clinical responses in patients with metastatic renal cell carcinoma: a phase II trial
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Bas D. Koster, Saskia J. A. M. Santegoets.
16. Acknowledgements
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16. Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues
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Amedeo Sciarra, Inês Monteiro, Christine Ménétrier-Caux.
