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Bioorganic Chemistry
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Volume 87, Pages 1-900 (June 2019), Hidden issue
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1. Editorial Board
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2. Issue TOC
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Tác giả
Fariba Peytam, Mehdi Adib, Shabnam Mahernia, Mahmoud Rahmanian-Jazi, ... Massoud Amanlou.
3. Isoindolin-1-one derivatives as urease inhibitors: Design, synthesis, biological evaluation, molecular docking and in-silico ADME evaluation
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Tác giả
Fariba Peytam, Mehdi Adib, Shabnam Mahernia, Mahmoud Rahmanian-Jazi, ... Massoud Amanlou.
4. Anti-diabetic potential of Pueraria lobata root extract through promoting insulin signaling by PTP1B inhibition
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Tác giả
Ran Sun, Xinxian Deng, Dongdong Zhang, Fangzhou Xie, ... Lei Fu.
5. Azacoccone E inhibits cancer cell growth by targeting 3-phosphoglycerate dehydrogenase
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Tác giả
Jing Guo, Xiaoxia Gu, Mengzhu Zheng, Yonghui Zhang, ... Hua Li.
6. Cucurbitane-type compounds from Momordica charantia: Isolation, in vitro antidiabetic, anti-inflammatory activities and in silico modeling approaches
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Tác giả
Siddanagouda R. Shivanagoudra, Wilmer H. Perera, Jose L. Perez, Giridhar Athrey, ... Bhimanagouda S. Patil.
7. Tyrosinase inhibition and anti-melanin generation effect of cinnamamide analogues
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Tác giả
Sultan Ullah, Chaeun Park, Muhammad Ikram, Dongwan Kang, ... Hyung Ryong Moon.
8. Development of novel 2-substituted acylaminoethylsulfonamide derivatives as fungicides against Botrytis cinerea
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Tác giả
Minlong Wang, Ying Du, Chunhui Liu, Xinling Yang, ... Xinghai Li.
9. The comparative study of the DNA binding and biological activities of the quaternized dicnq as a dicationic form and its platinum(II) heteroleptic cationic complex
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Tác giả
Ufuk Yıldız, Abdurrahman Şengül, Irfan Kandemir, Füsun Cömert, ... Burak Coban.
10. Synthesis of benzensulfonamides linked to quinazoline scaffolds as novel carbonic anhydrase inhibitors
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Tác giả
Adel S. El-Azab, Alaa A.-M. Abdel-Aziz, Sivia Bua, Alessio Nocentini, ... Claudiu T. Supuran.
11. Synthesis and characterization of novel bromophenols: Determination of their anticholinergic, antidiabetic and antioxidant activities
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Tác giả
Necla Öztaşkın, Rüya Kaya, Ahmet Maraş, Ertan Şahin, ... Süleyman Göksu.
12. Synthesis of compounds having antimicrobial activity from alginate
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Tác giả
Verónica Luque-Agudo, Jesús Albarrán-Velo, Mark E. Light, José M. Padrón, ... M. Victoria Gil.
13. Synthesis and antiproliferative activity of new 2-glyco-3-nitro-2H-chromenes
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Verónica Luque-Agudo, Jesús Albarrán-Velo, Mark E. Light, José M. Padrón, ... M. Victoria Gil.
14. Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells
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Tác giả
Tae Kyoung Lee, Dahae Lee, Seoung Rak Lee, Yoon-Joo Ko, ... Ki Hyun Kim.
15. Synthesis and evaluation of novel α-substituted chalcones with potent anti-cancer activities and ability to overcome multidrug resistance
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Tác giả
Sharon Riaz, Maheen Iqbal, Rahim Ullah, Rida Zahra, ... Rahman Shah Zaib Saleem.
16. Iridoids from Valeriana jatamansi induce autophagy-associated cell death via the PDK1/Akt/mTOR pathway in HCT116 human colorectal carcinoma cells
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Yu-Zhu Tan, Cheng Peng, Chang-Jiang Hu, Hong-Xiang Li, ... Zhi-Xing Cao.
17. Synthesis of CC, CN coupled novel substituted dibutyl benzothiazepinone derivatives and evaluation of their thrombin inhibitory activity
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Tác giả
C.P. Baburajeev, Chakrabhavi Dhananjaya Mohan, Vijay Pandey, Shobith Rangappa, ... Basappa.
18. Synthesis and characterization of new thiosemicarbazones, as potent urease inhibitors: In vitro and in silico studies
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Tác giả
Muhammad Islam, Ajmal Khan, Muhammad Tariq Shehzad, Abdul Hameed, ... Ahmed Al-Harrasi.
19. Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers
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Tác giả
Muhammet Tanc, Matthias Cleenewerck, Ammar Kurdi, Ria Roelandt, ... Pieter Van der Veken.
20. Evaluation of guanylhydrazone derivatives as inhibitors of Candida rugosa digestive lipase: Biological, biophysical, theoretical studies and biotechnological application
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Camilla C. Santana, Edeíldo F. Silva-Júnior, João César N. Santos, Érica E. da S. Rodrigues, ... Luciano Aparecido M. Grillo.
21. Pomalidomide hybrids act as proteolysis targeting chimeras: Synthesis, anticancer activity and B-Raf degradation
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Hong Chen, Feihong Chen, Sinan Pei, Shaohua Gou.
22. Development of a versatile DNMT and HDAC inhibitor C02S modulating multiple cancer hallmarks for breast cancer therapy
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Zigao Yuan, Shaopeng Chen, Chunmei Gao, Qiuzi Dai, ... Yuyang Jiang.
23. Rhamnolipid inspired lipopeptides effective in preventing adhesion and biofilm formation of Candida albicans
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Milos Jovanovic, Jelena Radivojevic, Kevin O'Connor, Stevan Blagojevic, ... Vladimir Savic.
24. Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models
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Tác giả
Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, ... Qiao-Hong Chen.
25. Structure-based design, synthesis and biological evaluation of a newer series of pyrazolo[1,5-a]pyrimidine analogues as potential anti-tubercular agents
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Tác giả
Palmi Modi, Shivani Patel, Mahesh Chhabria.
26. Anticancer and DNA binding studies of potential amino acids based quinazolinone analogs: Synthesis, SAR and molecular docking
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Tác giả
K.P. Rakesh, H.K. Kumara, H.M. Manukumar, D. Channe Gowda.
27. Characterization, quantitation, similarity evaluation and combination with Na+,K+-ATPase of cardiac glycosides from Streblus asper
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Yidan Bai, Wanfang Zhu, Yunhui Xu, Zijian Xie, ... Jie Zhang.
28. Interaction of C20-substituted derivative of pregnenolone acetate with copper (II) leads to ROS generation, DNA cleavage and apoptosis in cervical cancer cells: Therapeutic potential of copper chelation for cancer treatment
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Atif Zafar, Swarnendra Singh, Sabahuddin Ahmad, Saman Khan, ... Imrana Naseem.
29. Inhibition of biofilm formation, quorum sensing activity and molecular docking study of isolated 3, 5, 7-Trihydroxyflavone from Alstonia scholaris leaf against P.aeruginosa
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Tác giả
M. Abinaya, M. Gayathri.
30. Synthesis, molecular docking studies, and antimicrobial evaluation of new structurally diverse ureas
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Tác giả
Mahadev Patil, Anurag Noonikara Poyil, Shrinivas D. Joshi, Shivaputra A. Patil, ... Alejandro Bugarin.
31. Bioassay-guided isolation of antioxidant and α-glucosidase inhibitory constituents from stem of Vigna angularis
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Feng Guo, Shuoyang Zhang, Xiuying Yan, Yuhan Dan, ... Zhiguo Yu.
32. Sulfenamide derivatives can improve transporter-mediated cellular uptake of metformin and induce cytotoxicity in human breast adenocarcinoma cell lines
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Tác giả
Magdalena Markowicz-Piasecka, Johanna Huttunen, Joanna Sikora, Kristiina M. Huttunen.
33. Synthesis of TPEN variants to improve cancer cells selective killing capacity
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Stephanie Schaefer-Ramadan, Maciej Barlog, Jim Roach, Mohammed Al-Hashimi, ... Khaled Machaca.
34. Cytotoxic polyhydroxy serratene triterpenoids from Lycopodium complanatum
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Tác giả
Qiuzhu Dong, Zhenxing Zou, Xiaohui Jia, Xia Yu, ... Kangping Xu.
35. Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells
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Tác giả
Matteo Falsini, Daniela Catarzi, Flavia Varano, Diego Dal Ben, ... Vittoria Colotta.
36. Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer’s disease
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Tác giả
Xiaoyu Zhang, Qing Song, Zhongcheng Cao, Yan Li, ... Yong Deng.
37. Hyperpatulols A–I, spirocyclic acylphloroglucinol derivatives with anti-migration activities from the flowers of Hypericum patulum
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Yang-Yang Liu, Zhen Ao, Qi-Qi Xu, Dong-Rong Zhu, ... Ling-Yi Kong.
38. NO inhibitory phytochemicals as potential anti-inflammatory agents from the twigs of Trigonostemon heterophyllus
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Yaru Xi, Lijun An, Xueyuan Yang, Ziteng Song, ... Yuanqiang Guo.
39. Design, synthesis, and carbonic anhydrase inhibition activity of benzenesulfonamide-linked novel pyrazoline derivatives
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Tác giả
Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Silvia Bua, Alessio Nocentini, ... Claudiu T. Supuran.
40. Organometallic ruthenium(II)-arene complexes with triphenylphosphine amino acid bioconjugates: Synthesis, characterization and biological properties
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Margareta Pernar, Zoran Kokan, Juran Kralj, Zoran Glasovac, ... Srećko I. Kirin.
41. Bioactive terpenoids from Euonymus verrucosus var. pauciflorus showing NO inhibitory activities
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Yuling Yang, Xueyuan Yang, Xuke Zhang, Ziteng Song, ... Yuanqiang Guo.
42. Design and synthesis of mono-and di-pyrazolyl-s-triazine derivatives, their anticancer profile in human cancer cell lines, and in vivo toxicity in zebrafish embryos
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Muhammad Farooq, Anamika Sharma, Zainab Almarhoon, Abudalla Al-Dhfyan, ... Fernando Albericio.
43. Meglumine as a green, efficient and reusable catalyst for synthesis and molecular docking studies of bis(indolyl)methanes as antioxidant agents
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Bakthavatchala Reddy Nemallapudi, Grigory V. Zyryanov, Balakrishna Avula, Mallikarjuna Reddy Guda, ... Sravya Gundala.
44. Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer’s disease
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Giovanni Ribaudo, Paolo Coghi, Enrico Zanforlin, Betty Yuen Kwan Law, ... Vincent Kam Wai Wong.
45. Synthesis and biological evaluation of new bisindole-imidazopyridine hybrids as apoptosis inducers
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Satish Sunkari, Srinivasa Reddy Bonam, A.V. Subba Rao, Sd Riyaz, ... Bathini Nagendra Babu.
46. Introduction of amino moiety enhances the inhibitory potency of 1-tetralone chalcone derivatives against LPS-stimulated reactive oxygen species production in RAW 264.7 macrophages
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Pramila Katila, Aastha Shrestha, Aarajana Shrestha, Ritina Shrestha, ... Eung-Seok Lee.
47. New benzyl pyridinium derivatives bearing 2,4-dioxochroman moiety as potent agents for treatment of Alzheimer’s disease: Design, synthesis, biological evaluation, and docking study
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Marjan Mollazadeh, Maryam Mohammadi-Khanaposhtani, Afsaneh Zonouzi, Hamid Nadri, ... Mohammad Mahdavi.
48. Sulfur, selenium and tellurium containing amines act as effective carbonic anhydrase activators
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Damiano Tanini, Antonella Capperucci, Claudiu T. Supuran, Andrea Angeli.
49. Natural product-based design, synthesis and biological evaluation of 2′,3,4,4′-tetrahydrochalcone analogues as antivitiligo agents
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Hui Zhong, Jia Zhou, Xiao-Hong An, Ying-Rong Hua, ... Jing Shang.
50. Dual targeting of PTP1B and glucosidases with new bifunctional iminosugar inhibitors to address type 2 diabetes
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Xhenti Ferhati, Camilla Matassini, Maria Giulia Fabbrini, Andrea Goti, ... Paolo Paoli.
51. Synthesis, evaluation and docking of novel pyrazolo pyrimidines as potent p38α MAP kinase inhibitors with improved anti-inflammatory, ulcerogenic and TNF-α inhibitory properties
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Kanagasabai Somakala, Sana Tariq, Mohd. Amir.
52. Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene
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Fawzia F. Alblewi, Rawda M. Okasha, Zainab M. Hritani, Hany M. Mohamed, ... Ahmed M. El-Agrody.
53. Multi-target-directed triazole derivatives as promising agents for the treatment of Alzheimer’s disease
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Anupamjeet Kaur, Sukhmani Mann, Amandeep Kaur, Nitesh Priyadarshi, ... Deepti Goyal.
54. Withanolides from Physalis peruviana showing nitric oxide inhibitory effects and affinities with iNOS
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Bangjian Dong, Lijun An, Xueyuan Yang, Xuke Zhang, ... Yuanqiang Guo.
55. Design, synthesis and evaluation of 2-(indolylmethylidene)-2,3-dihydro-1-benzofuran-3-one and 2-(indolyl)-4H-chromen-4-one derivatives as novel monoamine oxidases inhibitors
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Koichi Takao, Shiori U, Hitoshi Kamauchi, Yoshiaki Sugita.
56. Synthesis, biological evaluation and molecular modelling studies of 1,3,7,8-tetrasubstituted xanthines as potent and selective A2A AR ligands with in vivo efficacy against animal model of Parkinson’s disease
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Tác giả
Suman Rohilla, Ranju Bansal, Sonja Kachler, Karl-Norbert Klotz.
57. New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study
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Elwira Chrobak, Monika Kadela-Tomanek, Ewa Bębenek, Krzysztof Marciniec, ... Stanisław Boryczka.
58. Tick-borne flavivirus reproduction inhibitors based on isoxazole core linked with adamantane
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Dmitry A. Vasilenko, Evgenia V. Dueva, Liubov I. Kozlovskaya, Nikolay A. Zefirov, ... Elena B. Averina.
59. Discovery of new inhibitors against both NF-κB and osteoclastogenesis from in-house library with α, β-unsaturated-enone fragment
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Chao Zhao, Dane Huang, Ruyue Li, Jiake Xu, ... Jun Xu.
60. In vitro and in silico studies of novel synthetic ACE-inhibitory peptides derived from Saccharomyces cerevisiae protein hydrolysate
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Mahta Mirzaei, Saeed Mirdamadi, Maliheh Safavi, Mahnaz Hadizadeh.
61. Design and synthesis of novel PARP-1 inhibitors based on pyridopyridazinone scaffold
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Ghada F. Elmasry, Enayat E. Aly, Fadi M. Awadallah, Samir M. El-Moghazy.
62. Unveiling novel diphenyl-1H-pyrazole based acrylates tethered to 1,2,3-triazole as promising apoptosis inducing cytotoxic and anti-inflammatory agents
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Mohemmed Faraz Khan, Tarique Anwer, Afroz Bakht, Garima Verma, ... Mohammad Shaquiquzzaman.
63. 5-Thioxoimidazolidine-2-one derivatives: Synthesis, anti-inflammatory activity, analgesic activity, COX inhibition assay and molecular modelling study
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Marwa A.M.Sh. El-Sharief, Samir Y. Abbas, Ahmed M.Sh. El-Sharief, Nermien M. Sabry, ... Mardia T. El Sayed.
64. Sanggenon O induced apoptosis of A549 cells is counterbalanced by protective autophagy
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Zhong-Rui Li, Ting Ma, Yan-Jia Guo, Bo Hu, ... Hong-Min Liu.
65. Design and synthesis of parthenolide-SAHA hybrids for intervention of drug-resistant acute myeloid leukemia
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Tác giả
Weizhi Ge, Zhongquan Liu, Yu Sun, Tianpeng Wang, ... Quan Zhang.
66. Design, synthesis and evaluation of a novel metal chelator as multifunctional agents for the treatment of Alzheimer’s disease
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Tác giả
Yingying Wang, Yue Yang, Kwon Ho Hong, Yao Ning, ... Jin Cai.
67. Natural flavonoid α-glucosidase inhibitors from Retama raetam: Enzyme inhibition and molecular docking reveal important interactions with the enzyme active site
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Usman Ghani, Mohammad Nur-e-Alam, Muhammad Yousaf, Zaheer Ul-Haq, ... Adnan J. Al-Rehaily.
68. Antioxidant and angiotensin-converting enzyme (ACE) inhibitory activity of thymosin alpha-1 (Thα1) peptide
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Jasmin Kharazmi-Khorassani, Ahmad Asoodeh, Hamid Tanzadehpanah.
69. Design, synthesis and biological evaluation of Helicobacter pylori inosine 5′-monophosphate dehydrogenase (HpIMPDH) inhibitors. Further optimization of selectivity towards HpIMPDH over human IMPDH2
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Chetan P. Shah, Gayathri Purushothaman, Vijay Thiruvenkatam, Sivapriya Kirubakaran, ... Prashant S. Kharkar.
70. Synthesis and biological evaluation of coumarin-1,3,4-oxadiazole hybrids as selective carbonic anhydrase IX and XII inhibitors
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Tác giả
Sridhar Goud Narella, Mohammed Ghouse Shaik, Arifuddin Mohammed, Mallika Alvala, ... Claudiu T. Supuran.
71. Probing the antibacterial and anticancer potential of tryptamine based mixed ligand Schiff base Ruthenium(III) complexes
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Manzoor Ahmad Malik, Md Kausar Raza, Ovas Ahmad Dar, Amadudin, ... Athar Adil Hashmi.
72. Furofuran lignans as a new series of antidiabetic agents exerting α-glucosidase inhibition and radical scarvenging: Semisynthesis, kinetic study and molecular modeling
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Tác giả
Wisuttaya Worawalai, Titiruetai Doungwichitrkul, Warin Rangubpit, Panyakorn Taweechat, ... Preecha Phuwapraisirisan.
73. Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies
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Tác giả
Mahmoud F. Abo-Ashour, Wagdy M. Eldehna, Alessio Nocentini, Hany S. Ibrahim, ... Claudiu T. Supuran.
74. Mechanistic investigation of anthocyanidin derivatives as α-glucosidase inhibitors
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Tác giả
Jang Hoon Kim, Hyo Young Kim, Chang Hyun Jin.
75. Evaluation of angularly condensed diquinothiazines as potential anticancer agents
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Tác giả
Małgorzata Jeleń, Krystian Pluta, Małgorzata Latocha, Beata Morak-Młodawska, ... Dariusz Kuśmierz.
76. Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential
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Ola S. Afifi, Omaima G. Shaaban, Heba A. Abd El Razik, Shams El-Dine A. Shams El-Dine, ... Marwa M. Abu-Serie.
77. Synthesis, biological activity and multiscale molecular modeling studies of bis-coumarins as selective carbonic anhydrase IX and XII inhibitors with effective cytotoxicity against hepatocellular carcinoma
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Belma Zengin Kurt, Aydan Dag, Berna Doğan, Serdar Durdagi, ... Fatih Sonmez.
78. Xanthine oxidase inhibitors from an endophytic fungus Lasiodiplodia pseudotheobromae
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Sanjay Kumar, Amol Dilip Pagar, Furkan Ahmad, Vagish Dwibedi, ... Inder Pal Singh.
79. Benzoxazinone-thiosemicarbazones as antidiabetic leads via aldose reductase inhibition: Synthesis, biological screening and molecular docking study
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Tác giả
Muhammad Tariq Shehzad, Aqeel Imran, Guy Sedar Singor Njateng, Abdul Hameed, ... Jamshed Iqbal.
80. Eight new glycosides with hepatoprotective activity isolated from the aerial parts of Morinda parvifolia
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Tác giả
Xianming Su, Li Li, Hua Sun, Fan Zhang, ... Jie Kang.
81. Fluorescent labeling of ursolic acid with FITC for investigation of its cytotoxic activity using confocal microscopy
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Tác giả
Tatiana S. Frolova, Alla V. Lipeeva, Dmitry S. Baev, Sergey I. Baiborodin, ... Olga I. Sinitsyna.
82. Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones
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Tác giả
Sulunay Parlar, Gozde Sayar, Ayse Hande Tarikogullari, Sumru Sozer Karadagli, ... Ulrike Holzgrabe.
83. Promising anti-inflammatory effects of chalcones via inhibition of cyclooxygenase, prostaglandin E2, inducible NO synthase and nuclear factor κb activities
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Tác giả
Haroon ur Rashid, Yiming Xu, Nasir Ahmad, Yaseen Muhammad, Lisheng Wang.
84. Phenylsulfonyl piperazine bridged [1,3]dioxolo[4,5-g]chromenones as promising antiproliferative and antioxidant agents
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Tác giả
Rahul V. Patel, Bhupendra M. Mistry, Riyaz Syed, Nikhil M. Parekh, Han-Seung Shin.
85. Natural and semisynthetic oxyprenylated aromatic compounds as stimulators or inhibitors of melanogenesis
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Salvatore Genovese, Francesco Epifano, Philippe de Medina, Nicolas Caron, ... Serena Fiorito.
86. Investigation of new quinoline derivatives as promising inhibitors of NTPDases: Synthesis, SAR analysis and molecular docking studies
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Tác giả
Komal Hayat, Saira Afzal, Altaf Saeed, Amna Murtaza, ... Abbas Hassan.
87. Glycopentanolones A-D, four new geranylated quinolone alkaloids from Glycosmis pentaphylla
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Yun-Hyeok Choi, Changon Seo, Wonsik Jeong, Ji Eun Lee, ... Seong Su Hong.
88. Lithocarols A-F, six tenellone derivatives from the deep-sea derived fungus Phomopsis lithocarpus FS508
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Tác giả
Jianlin Xu, Zhaoming Liu, Yuchan Chen, Haibo Tan, ... Weimin Zhang.
