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Drug Discovery Today
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Volume 24, Issue 11
Pages 2105-2224 (November 2019)
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1. Contents page 1
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Nội dung
Page i
2. Contents page 2
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Page ii
3. The Art of Virtualizing Pharma R&D
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Tác giả
Alexander Schuhmacher, Oliver Gassmann, Michael Kuss, Markus Hinder.
Nội dung
Pages 2105-2107
4. Trapping endothelin-1 to hunt down cardiovascular disease?
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Tác giả
Bernhard Wernly, Christian Jung.
Nội dung
Pages 2108-2110
5. Target 2035: probing the human proteome
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Adrian J. Carter, Oliver Kraemer, Matthias Zwick, Anke Mueller-Fahrnow.
Nội dung
Pages 2111-2115
6. Regulatory sanctions for ethically relevant GCP violations
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Rosemarie de la Cruz Bernabe, Ghislaine J.M.W. van Thiel, Nancy S. Breekveldt, Christine C. Gispen, Johannes J.M. van Delden.
Nội dung
Pages 2116-2119
7. CDx, NGS and regulation: five perspectives from the Pistoia Alliance
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John Wise, Mike Furness, Stewart McWilliams, Simon Patton.
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Pages 2120-2125
8. Pharmacological analysis of CFTR variants of cystic fibrosis using stem cell-derived organoids
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Kevin G. Chen, Pingyu Zhong, Wei Zheng, Jeffrey M. Beekman.
Nội dung
Pages 2126-2138
9. A human-on-a-chip approach to tackling rare diseases
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Camilly P. Pires de Mello, John Rumsey, Victoria Slaughter, James J. Hickman.
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Pages 2139-2151
10. Pharmaceutical applications of cyclotides
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Paola G. Ojeda, Marlon H. Cardoso, Octávio L. Franco.
Nội dung
Pages 2152-2161
11. Reaching for the bright StARs in chemical space
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José L. Medina-Franco, J. Jesús Naveja, Edgar López-López.
Nội dung
Pages 2162-2169
12. Novel insights into the role of urotensin II in cardiovascular disease
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João Pereira-Castro, Carmen Brás-Silva, Ana Patrícia Fontes-Sousa.
Nội dung
Pages 2170-2180
13. PI3K/AKT/mTOR pathway inhibitors in triple-negative breast cancer: a review on drug discovery and future challenges
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Tác giả
Mohammad A. Khan, Vineet K. Jain, Md. Rizwanullah, Javed Ahmad, Keerti Jain.
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Pages 2181-2191
14. Nuclear G-protein-coupled receptors as putative novel pharmacological targets
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Rita Ribeiro-Oliveira, Martin Vojtek, Salomé Gonçalves-Monteiro, Maria Sofia Vieira-Rocha.
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Pages 2192-2201
15. Animal venoms: therapeutic tools for tackling Parkinson’s disease
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Henrique de Oliveira Amaral, Victoria Monge-Fuentes, Andréia Biolchi Mayer, Gabriel Avohay Alves Campos.
Nội dung
Pages 2202-2211
16. Targeted cell delivery for articular cartilage regeneration and osteoarthritis treatment
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Tác giả
Nahid Nasiri, Samaneh Hosseini, Mauro Alini, Ali Khademhosseini, Mohamadreza Baghaban Eslaminejad.
Nội dung
Pages 2212-2224