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Alzheimer's & Dementia: Translational Research & Clinical Interventions Open access
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Volume 5 In progress (2019)
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1. The effects of information and communication technologies on informal caregivers of persons living with dementia: A systematic review
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Robert J. Lucero, Elizabeth A. Fehlberg, Aditi G.M. Patel, Ragnhildur I. Bjarnardottir, ... Mary Mittelman.
2. A phase 1 clinical trial of the sigma-2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease
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Tác giả
Michael Grundman, Roger Morgan, Jason D. Lickliter, Lon S. Schneider, ... Susan M. Catalano.
3. Amyloid β perturbs elevated heme flux induced with neuronal development
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Tác giả
Chantal Vidal, Kelly Daescu, Keely E. Fitzgerald, Anna Starokadomska, ... Li Zhang.
4. The Alzheimer's disease THErapy with NEuroaid (ATHENE) study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer's disease stable on cholinesterase inhibitors or memantine—A randomized, double-bl
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Tác giả
Christopher L.H. Chen, Purabi Reang Sharma, Boon Yeow Tan, Casuarine Low, Narayanaswamy.
5. Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance research database of Taiwan
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Tác giả
Chee-Jen Chang, Tse-Chih Chou, Chiung-Chih Chang, Ta-Fu Chen, ... Chin-Chang Huang.
6. Plasma exchange for Alzheimer's disease Management by Albumin Replacement (AMBAR) trial: Study design and progress
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Tác giả
Mercè Boada, Oscar López, Laura Núñez, Zbigniew M. Szczepiorkowski, ... Antonio Páez.
7. Effects of the dual orexin receptor antagonist DORA-22 on sleep in 5XFAD mice
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Tác giả
Marilyn J. Duncan, Hannah Farlow, Chairtra Tirumalaraju, Do-Hyun Yun, ... Adam D. Bachstetter.
8. Neuropsychiatric symptoms in patients with dementia and the longitudinal costs of informal care in the Cache County population
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Tác giả
Gail B. Rattinger, Chelsea L. Sanders, Elizabeth Vernon, Sarah Schwartz, ... JoAnn T. Tschanz.
9. No synergistic effect of subtherapeutic doses of donepezil and EVP-6124 in healthy elderly subjects in a scopolamine challenge model
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Tác giả
Anne Catrien Baakman, Ricardo Alvarez-Jimenez, Gordon Loewen, Marieke L. de Kam, ... Geert Jan Groeneveld.
10. Patients with Alzheimer's disease who carry the APOE ε4 allele benefit more from physical exercise
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Tác giả
Camilla Steen Jensen, Anja Hviid Simonsen, Volkert Siersma, Nina Beyer, ... Steen Gregers Hasselbalch.
11. General and domain-specific cognitive reserve, mild cognitive impairment, and dementia risk in older women
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Andrew J. Petkus, Susan M. Resnick, Stephen R. Rapp, Mark A. Espeland, ... Jiu-Chiuan Chen.
12. Differential effects of neurodegeneration biomarkers on subclinical cognitive decline
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Tác giả
Andrew P. Merluzzi, Nicholas M. Vogt, Derek Norton, Erin Jonaitis, ... Barbara B. Bendlin.
13. Pregnancy loss and risk of later dementia: A nationwide cohort study, Denmark, 1977–2017
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Tác giả
Saima Basit, Jan Wohlfahrt, Heather A. Boyd.
14. In vitro degradation of β-amyloid fibrils by microbial keratinase
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Tác giả
Debananda S. Ningthoujam, Saikat Mukherjee, Laishram Jaya Devi, Elangbam Shanta Singh, ... Debashis Mukhopadhyay.
15. Enrichment factors for clinical trials in mild-to-moderate Alzheimer's disease
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Tác giả
Clive Ballard, Alireza Atri, Neli Boneva, Jeffrey L. Cummings, ... Lars Lau Raket.
16. Analysis of dementia in the US population using Medicare claims: Insights from linked survey and administrative claims data
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Tác giả
Yi Chen, Bryan Tysinger, Eileen Crimmins, Julie M. Zissimopoulos.
17. Moderate- to high-intensity exercise does not modify cortical β-amyloid in Alzheimer's disease
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Tác giả
Kristian S. Frederiksen, Karine Madsen, Birgitte B. Andersen, Nina Beyer, ... Ian Law.
18. A 24-week double-blind placebo-controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptoms
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Tác giả
Katy Bernard, Sylvie Gouttefangeas, Sylvie Bretin, Stéphanie Galtier, ... Maria Pueyo.
19. Effects of pioglitazone on mnemonic hippocampal function: A blood oxygen level–dependent functional magnetic resonance imaging study in elderly adults
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Tác giả
Annchen R. Knodt, James R. Burke, Kathleen A. Welsh-Bohmer, Brenda L. Plassman, ... Ahmad R. Hariri.
20. Using data science to diagnose and characterize heterogeneity of Alzheimer's disease
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Tác giả
Ting F.A. Ang, Ning An, Huitong Ding, Sherral Devine, ... Honghuang Lin.
21. Alzheimer's disease drug development pipeline: 2019
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Tác giả
Jeffrey Cummings, Garam Lee, Aaron Ritter, Marwan Sabbagh, Kate Zhong.
22. Alzheimer's disease medication and risk of all-cause mortality and all-cause hospitalization: A retrospective cohort study
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Tác giả
Sandipan Bhattacharjee, Asad E. Patanwala, Wei-Hsuan Lo-Ciganic, Daniel C. Malone, ... William J. Burke.
23. Study protocol of the self-monitoring activity program: Effects of activity on incident dementia
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Tác giả
Hiroyuki Shimada, Sangyoon Lee, Takehiko Doi, Seongryu Bae, ... Hidenori Arai.
24. The relative efficiency of time-to-progression and continuous measures of cognition in presymptomatic Alzheimer's disease
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Tác giả
Dan Li, Samuel Iddi, Paul S. Aisen, Wesley K. Thompson, ... Michael C. Donohue.
25. Promising results from a pilot study to reduce distress in Vietnamese American dementia and memory loss caregivers
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Tác giả
Van M. Ta Park, Vy Ton, Quyen Q. Tiet, Quyen Vuong, ... Dolores Gallagher-Thompson.
26. Magnetic resonance imaging measures of brain atrophy from the EXPEDITION3 trial in mild Alzheimer's disease
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Tác giả
Adam J. Schwarz, Karen L. Sundell, Arnaud Charil, Michael G. Case, ... Eric R. Siemers.
27. Rates of lobar atrophy in asymptomatic MAPT mutation carriers
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Tác giả
Qin Chen, Bradley F. Boeve, Matthew Senjem, Nirubol Tosakulwong, ... Kejal Kantarci
28. Longitudinal analysis of risk factors for dementia based on Mild Cognitive Impairment Screen results and questionnaire responses from healthy Japanese individuals registered in an online database
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Tác giả
Masayo Ogawa, Kazushi Maruo, Daichi Sone, Hiroyuki Shimada, ... Hidehiro Mizusawa.
29. Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials
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Tác giả
J. Scott Andrews, Urvi Desai, Noam Y. Kirson, Miriam L. Zichlin, ... Brandy R. Matthews.
30. Identification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study
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Tác giả
Takuya Yagi, Michio Kanekiyo, Junichi Ito, Ryoko Ihara, ... Ken Aoshima.
31. Focused transcranial ultrasound for treatment of neurodegenerative dementia
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Tác giả
Natalie Eleanor Nicodemus, Sergio Becerra, Taylor P. Kuhn, Hannah R. Packham, ... Sheldon Jordan.
32. Economic impacts of introducing diagnostics for mild cognitive impairment Alzheimer's disease patients
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Tác giả
Raphael Wittenberg, Martin Knapp, Maria Karagiannidou, John Dickson, Jonathan M. Schott.
33. Analyses of natural courses of Japanese patients with Alzheimer's disease using placebo data from placebo-controlled, randomized clinical trials: Japanese Study on the Estimation of Clinical course of Alzheimer's disease
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Tác giả
Mitsunori Watanabe, Yu Nakamura, Yasumasa Yoshiyama, Tatsuo Kagimura, ... Akira Homma.
34. Key factors for the assessment of mobility in advanced dementia: A consensus approach
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Tác giả
Karen Van Ooteghem, Kristin E. Musselman, Avril Mansfield, David Gold, ... Andrea Iaboni.
35. Assessment of need and practice for assistive technology and telecare for people with dementia—The ATTILA (Assistive Technology and Telecare to maintain Independent Living At home for people with dementia) trial.
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Tác giả
Kirsty Forsyth, Catherine Henderson, Lucy Davis, Anusua Singh Roy, ... Robert Howard.
36. Are antidementia drugs associated with reduced mortality after a hospital emergency admission in the population with dementia aged 65 years and older?
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Tác giả
Simona Hapca, Jennifer Kirsty Burton, Vera Cvoro, Emma Reynish, Peter T. Donnan.
37. Chinese herbal medicine Qinggongshoutao for the treatment of amnestic mild cognitive impairment: A 52-week randomized controlled trial
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Tác giả
Jinzhou Tian, Jing Shi, Mingqing Wei, Jingnian Ni, ... Yongyan Wang.
38. Two-period linear mixed effects models to analyze clinical trials with run-in data when the primary outcome is continuous: Applications to Alzheimer's disease
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Tác giả
Guoqiao Wang, Andrew J. Aschenbrenner, Yan Li, Eric McDade, ... Chengjie Xiong.
39. The role of acetylcholinesterase inhibitors such as neostigmine and rivastigmine on chronic pain and cognitive function in aging: A review of recent clinical applications
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Tác giả
Jabril Eldufani, Gilbert Blaise.
40. The protective effects of polyphenols on Alzheimer's disease: A systematic review
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Tác giả
Chiara Colizzi.
41. A model of lipid dysregulation and altered nutrient status in Alzheimer's disease
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Tác giả
Keith Fluegge.
42. From brain collections to modern brain banks: A historical perspective
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Tác giả
Arenn Faye Carlos, Tino Emanuele Poloni, Valentina Medici, Maia Chikhladze, ... Mauro Ceroni.
43. FDA position statement “Early Alzheimer's disease: Developing drugs for treatment, Guidance for Industry”
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Tác giả
Marwan N. Sabbagh, Suzanne Hendrix, John E. Harrison.
44. White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities
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Tác giả
Jessica Alber, Suvarna Alladi, Hee-Joon Bae, David A. Barton, ... Atticus H. Hainsworth.
45. The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease
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Tác giả
Cristina Lopez Lopez, Pierre N. Tariot, Angelika Caputo, Jessica B. Langbaum, ... Eric M. Reiman.
46. Reconsidering frameworks of Alzheimer's dementia when assessing psychosocial outcomes
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Tác giả
Joseph E. Gaugler, Lisa J. Bain, Lauren Mitchell, Jessica Finlay, ... Sheryl Zimmerman.
47. Pharmaceutical company payments to the authors of the Japanese dementia clinical practice guidelines in 2016
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Tác giả
Yuki Shimada, Akihiko Ozaki, Hiroaki Saito, Toyoaki Sawano, Tetsuya Tanimoto.